CHEMBL2426364


SMILES O=C(c1ccc(C(=O)N2CCC(N3CCCC3)CC2)c(Nc2ccccc2)c1)N1CCC(N2CCCC2)CC1
InChIKey PQOOIERVZAXHBP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 529.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.37 5.37 5.37 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.05 6.05 6.05 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.14 7.14 7.14 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.01 7.01 7.01 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.4 6.4 6.4 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.07 6.07 6.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 5.46 5.46 5.46 ChEMBL