pobilukast


SMILES OC(=O)CCS[C@H](c1ccccc1CCCCCCCCc1ccccc1)[C@H](C(=O)O)O
InChIKey PZIFPMYXXCAOCC-JWQCQUIFSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 16
Molecular weight (Da) 458.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CysLT1 CLTR1 Human Leukotriene A pKi 7.1 7.1 7.1 Guide to Pharmacology
CysLT1 CLTR1 Guinea pig Leukotriene A pKi 8.3 8.3 8.3 ChEMBL
CysLT1 CLTR1 Human Leukotriene A pKi 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CysLT1 CLTR1 Human Leukotriene A pIC50 7.89 7.89 7.89 Guide to Pharmacology
CysLT2 CLTR2 Human Leukotriene A pA2 6.2 6.2 6.2 Guide to Pharmacology