CHEMBL2435407


SMILES O=C1N(Cc2c[nH]c3ccccc23)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey VPARAVFFNOQZEG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.5 6.52 6.54 ChEMBL
OX1 OX1R Human Orexin A pKd 6.43 6.43 6.43 ChEMBL
OX2 OX2R Human Orexin A pKi 7.21 7.37 7.52 ChEMBL
OX2 OX2R Human Orexin A pKd 7.38 7.38 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database