CHEMBL2435412


SMILES O=C1CCCC2(CCN(c3cnc4ccccc4n3)CC2)N1Cc1c[nH]c2ccccc12
InChIKey OBJJCTFQGWCXGH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.56 6.59 6.63 ChEMBL
OX1 OX1R Human Orexin A pKd 6.69 6.69 6.69 ChEMBL
OX2 OX2R Human Orexin A pKi 7.16 7.25 7.33 ChEMBL
OX2 OX2R Human Orexin A pKd 6.71 6.71 6.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database