CHEMBL286565


SMILES COc1cccc(OC)c1OCCNC[C@H]1Oc2ccccc2O[C@@H]1c1ccc(C)cc1
InChIKey UNHGFWKSHHCRHF-JWQCQUIFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Bovine Adrenoceptors A pKi 8.08 8.08 8.08 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 6.72 6.72 6.72 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKi 6.11 6.11 6.11 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.71 6.71 6.71 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.39 7.39 7.39 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.08 6.08 6.08 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database