GPCRdb

CHEMBL28312

Agent/drug
Bioactivity

CHEMBL28312

SMILES	CCCN(CCCCNC(=O)c1ccccc1OC)C1COc2cccc(OC)c2C1
InChIKey	CZSCSNOFEQMOLJ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	11
Molecular weight (Da)	426.3

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	9.30	9.30	9.30	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	ADA1A	Bovine	Adrenoceptors	A	pIC50	5.52	5.52	5.52	ChEMBL
α_2A	ADA2A	Bovine	Adrenoceptors	A	pIC50	7.00	7.00	7.00	ChEMBL
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pIC50	9.00	9.00	9.00	ChEMBL
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pIC50	6.00	6.00	6.00	ChEMBL
5-HT_2A	5HT2A	Bovine	5-Hydroxytryptamine	A	pIC50	5.40	5.40	5.40	ChEMBL
D₂	DRD2	Bovine	Dopamine	A	pIC50	8.00	8.00	8.00	ChEMBL

Showing 1 to 6 of 6 entries

CHEMBL28312

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.