GPCRdb

CHEMBL285843

Agent/drug
Bioactivity

CHEMBL285843

SMILES	NC(CCP(=O)(O)O)C(=O)O
InChIKey	DDOQBQRIEWHWBT-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	4
Rotatable bonds	4
Molecular weight (Da)	183.0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₂	GRM2	Rat	Metabotropic glutamate	C	pKi	5.00	5.00	5.00	PDSP Ki database
mGlu₄	GRM4	Rat	Metabotropic glutamate	C	pKi	6.40	6.40	6.40	PDSP Ki database
mGlu₆	GRM6	Rat	Metabotropic glutamate	C	pKi	6.40	6.40	6.40	PDSP Ki database
mGlu₆	GRM6	Human	Metabotropic glutamate	C	pKi	6.05	6.05	6.05	PDSP Ki database
mGlu₇	GRM7	Human	Metabotropic glutamate	C	pKi	5.00	5.00	5.00	PDSP Ki database
mGlu₈	GRM8	Rat	Metabotropic glutamate	C	pKi	5.57	5.74	5.90	PDSP Ki database
mGlu₈	GRM8	Human	Metabotropic glutamate	C	pKi	6.40	6.40	6.40	PDSP Ki database

Showing 1 to 7 of 7 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₄	GRM4	Human	Metabotropic glutamate	C	pEC50	6.48	6.48	6.48	ChEMBL
mGlu₆	GRM6	Rat	Metabotropic glutamate	C	pEC50	6.00	6.00	6.00	ChEMBL
mGlu₆	GRM6	Human	Metabotropic glutamate	C	pEC50	6.55	6.55	6.55	ChEMBL
mGlu₈	GRM8	Human	Metabotropic glutamate	C	pIC50	8.29	8.29	8.29	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL285843

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.