OLICERIDINE


SMILES COc1ccsc1CNCC[C@@]1(c2ccccn2)CCOC2(CCCC2)C1
InChIKey DMNOVGJWPASQDL-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 8EFB

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 8.22 8.53 8.84 ChEMBL
μ OPRM Human Opioid A pKi 8.09 8.09 8.09 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 5.55 5.55 5.55 ChEMBL
κ OPRK Human Opioid A pEC50 5.85 5.85 5.85 ChEMBL
μ OPRM Human Opioid A pEC50 7.3 8.06 8.74 ChEMBL
NOP OPRX Human Opioid A pEC50 8.13 8.13 8.13 Drug Central