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Ligand source activities (1 row/activity)

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Ligands (move mouse cursor over ligand name to see structure)					Receptor		Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found		Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found

Ligands (move mouse cursor over ligand name to see structure)					Receptor	Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found	Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found
	44439758	91304	None	0	Human	Functional	pEC50	=	8	8.0	1995	2	Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assay	ChEMBL	551	8	6	11	0.6	O=c1c2cc(Cl)ccc2ccn1[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O	10.1016/j.bmcl.2006.09.017
	CHEMBL240201	91304	None	0	Human	Functional	pEC50	=	8	8.0	1995	2	Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assay	ChEMBL	551	8	6	11	0.6	O=c1c2cc(Cl)ccc2ccn1[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O	10.1016/j.bmcl.2006.09.017
	10168108	145391	None	0	Human	Functional	pEC50	=	8	8.0	-	1	Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assay	ChEMBL	575	8	6	11	1.8	O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](c2nc3cc(C(F)(F)F)ccc3s2)[C@H](O)[C@@H]1O	10.1016/j.bmcl.2006.10.038
	CHEMBL391317	145391	None	0	Human	Functional	pEC50	=	8	8.0	-	1	Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assay	ChEMBL	575	8	6	11	1.8	O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](c2nc3cc(C(F)(F)F)ccc3s2)[C@H](O)[C@@H]1O	10.1016/j.bmcl.2006.10.038
	148197	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptorAgonist activity at P2Y2 receptor	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm1016297
	148197.0	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptorAgonist activity at P2Y2 receptor	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm1016297
	1736	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptorAgonist activity at P2Y2 receptor	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm1016297
	4900	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptorAgonist activity at P2Y2 receptor	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm1016297
	CHEMBL221326	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptorAgonist activity at P2Y2 receptor	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm1016297
	DB15919	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptorAgonist activity at P2Y2 receptor	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm1016297
	148197	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cellsAgonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cells	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	148197.0	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cellsAgonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cells	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	1736	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cellsAgonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cells	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	4900	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cellsAgonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cells	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	CHEMBL221326	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cellsAgonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cells	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	DB15919	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cellsAgonist activity at P2Y2 receptor (unknown origin) expressed in human 1321N1 cells	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	1734	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at P2Y2 receptor in human CF/T43 cellsAgonist activity at P2Y2 receptor in human CF/T43 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	3639	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at P2Y2 receptor in human CF/T43 cellsAgonist activity at P2Y2 receptor in human CF/T43 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	6133	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at P2Y2 receptor in human CF/T43 cellsAgonist activity at P2Y2 receptor in human CF/T43 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	CHEMBL336296	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at P2Y2 receptor in human CF/T43 cellsAgonist activity at P2Y2 receptor in human CF/T43 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	DB04005	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at P2Y2 receptor in human CF/T43 cellsAgonist activity at P2Y2 receptor in human CF/T43 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1016/j.bmc.2017.11.043
	148197	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	148197.0	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	1736	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	4900	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	CHEMBL221326	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	DB15919	1438	None	20	Human	Functional	pEC50	=	7	7.0	1	3	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	790	14	10	21	-4.2	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	1734	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	3639	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	6133	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	CHEMBL336296	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	DB04005	3966	None	29	Human	Functional	pEC50	=	7	7.0	1	7	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/jm901450d
	44457427	14863	None	0	Human	Functional	pEC50	=	7	7.0	6	3	Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 receptorAgonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 receptor	ChEMBL	790	14	10	21	-4.2	O=c1ccn([C@H]2O[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n4ccc(=O)[nH]c4=O)[C@H](O)[C@@H]3O)[C@H](O)[C@@H]2O)c(=O)[nH]1	10.1016/s0960-894x(00)00612-0
	CHEMBL1207447	14863	None	0	Human	Functional	pEC50	=	7	7.0	6	3	Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 receptorAgonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 receptor	ChEMBL	790	14	10	21	-4.2	O=c1ccn([C@H]2O[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n4ccc(=O)[nH]c4=O)[C@H](O)[C@@H]3O)[C@H](O)[C@@H]2O)c(=O)[nH]1	10.1016/s0960-894x(00)00612-0
	CHEMBL406266	14863	None	0	Human	Functional	pEC50	=	7	7.0	6	3	Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 receptorAgonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 receptor	ChEMBL	790	14	10	21	-4.2	O=c1ccn([C@H]2O[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n4ccc(=O)[nH]c4=O)[C@H](O)[C@@H]3O)[C@H](O)[C@@H]2O)c(=O)[nH]1	10.1016/s0960-894x(00)00612-0
	1713	520	None	42	Human	Functional	pEC50	=	6	6.0	-9	10	Agonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium levelAgonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium level	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/jm801442p
	5957	520	None	42	Human	Functional	pEC50	=	6	6.0	-9	10	Agonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium levelAgonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium level	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/jm801442p
	91	520	None	42	Human	Functional	pEC50	=	6	6.0	-9	10	Agonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium levelAgonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium level	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/jm801442p
	CHEMBL14249	520	None	42	Human	Functional	pEC50	=	6	6.0	-9	10	Agonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium levelAgonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium level	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/jm801442p
	DB00171	520	None	42	Human	Functional	pEC50	=	6	6.0	-9	10	Agonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium levelAgonist activity at N-terminal HA epitope-tagged human P2Y2 receptor C278S mutant expressed in human 1321N1 cells assessed as increase in intracellular calcium level	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/jm801442p
	57394895	71337	None	0	Human	Functional	pEC50	=	6	6.0	-	1	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as stimulation of PLC-induced [3H]inositol phosphate production after 30 mins by scintillation countingAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as stimulation of PLC-induced [3H]inositol phosphate production after 30 mins by scintillation counting	ChEMBL	412	5	5	7	-0.3	Cc1ccc(-c2cn([C@@H]3O[C@H](CCP(=O)(O)O)[C@@H](O)[C@H]3O)c(=O)[nH]c2=O)cc1	10.1016/j.bmc.2012.02.012
	CHEMBL1957442	71337	None	0	Human	Functional	pEC50	=	6	6.0	-	1	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as stimulation of PLC-induced [3H]inositol phosphate production after 30 mins by scintillation countingAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as stimulation of PLC-induced [3H]inositol phosphate production after 30 mins by scintillation counting	ChEMBL	412	5	5	7	-0.3	Cc1ccc(-c2cn([C@@H]3O[C@H](CCP(=O)(O)O)[C@@H](O)[C@H]3O)c(=O)[nH]c2=O)cc1	10.1016/j.bmc.2012.02.012
	44219764	193372	None	2	Human	Functional	pEC50	=	6	6.0	-	1	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating G protein assessed as inositol phosphate production by scintillation proximity assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating G protein assessed as inositol phosphate production by scintillation proximity assay	ChEMBL	480	7	7	11	-1.9	O=c1ccn([C@@H]2O[C@H](/C=C/P(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1	10.1016/j.bmcl.2009.04.027
	CHEMBL523850	193372	None	2	Human	Functional	pEC50	=	6	6.0	-	1	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating G protein assessed as inositol phosphate production by scintillation proximity assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating G protein assessed as inositol phosphate production by scintillation proximity assay	ChEMBL	480	7	7	11	-1.9	O=c1ccn([C@@H]2O[C@H](/C=C/P(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1	10.1016/j.bmcl.2009.04.027
	1783	3925	None	23	Human	Functional	pEC50	=	5	5.0	-524	7	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cellsAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells	ChEMBL	566	9	9	16	-4.8	OC[C@H]1O[C@H](OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)[C@@H]([C@H]([C@@H]1O)O)O	10.1016/j.bmc.2009.05.024
	8629	3925	None	23	Human	Functional	pEC50	=	5	5.0	-524	7	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cellsAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells	ChEMBL	566	9	9	16	-4.8	OC[C@H]1O[C@H](OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)[C@@H]([C@H]([C@@H]1O)O)O	10.1016/j.bmc.2009.05.024
	CHEMBL375951	3925	None	23	Human	Functional	pEC50	=	5	5.0	-524	7	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cellsAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells	ChEMBL	566	9	9	16	-4.8	OC[C@H]1O[C@H](OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)[C@@H]([C@H]([C@@H]1O)O)O	10.1016/j.bmc.2009.05.024
	DB01861	3925	None	23	Human	Functional	pEC50	=	5	5.0	-524	7	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cellsAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells	ChEMBL	566	9	9	16	-4.8	OC[C@H]1O[C@H](OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)[C@@H]([C@H]([C@@H]1O)O)O	10.1016/j.bmc.2009.05.024
	145968441	163724	None	0	Human	Functional	pEC50	=	5.0	5.0	-	1	Agonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as [3H]-inositol phosphate accumulation measured after 90 mins by anion exchange chromatographic methodAgonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as [3H]-inositol phosphate accumulation measured after 90 mins by anion exchange chromatographic method	ChEMBL	553	9	6	14	-2.0	O=c1nc(N2CCOCC2)ccn1[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O	10.1016/j.bmc.2017.11.043
	CHEMBL4203866	163724	None	0	Human	Functional	pEC50	=	5.0	5.0	-	1	Agonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as [3H]-inositol phosphate accumulation measured after 90 mins by anion exchange chromatographic methodAgonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as [3H]-inositol phosphate accumulation measured after 90 mins by anion exchange chromatographic method	ChEMBL	553	9	6	14	-2.0	O=c1nc(N2CCOCC2)ccn1[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O	10.1016/j.bmc.2017.11.043

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Ligands (move mouse cursor over ligand name to see structure)					Receptor		Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found		Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found

Ligands (move mouse cursor over ligand name to see structure)					Receptor	Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found	Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found
	1734	3966	None	29	Human	Binding	pEC50	=	6.9	6.9	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/acs.jmedchem.5b01972
	3639	3966	None	29	Human	Binding	pEC50	=	6.9	6.9	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/acs.jmedchem.5b01972
	6133	3966	None	29	Human	Binding	pEC50	=	6.9	6.9	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/acs.jmedchem.5b01972
	CHEMBL336296	3966	None	29	Human	Binding	pEC50	=	6.9	6.9	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/acs.jmedchem.5b01972
	DB04005	3966	None	29	Human	Binding	pEC50	=	6.9	6.9	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	484	8	7	12	-2.5	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O	10.1021/acs.jmedchem.5b01972
	1737	1367	None	7	Human	Binding	pEC50	=	6.7	6.7	-	0	Agonist activity at human P2Y2Agonist activity at human P2Y2	ChEMBL	773	14	9	21	-2.9	Nc1ccn(c(=O)n1)[C@@H]1O[C@@H]([C@H](C1)O)COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1ccc(=O)[nH]c1=O)O)O)O)O	10.1021/acs.jmedchem.5b01972
	9875516	1367	None	7	Human	Binding	pEC50	=	6.7	6.7	-	0	Agonist activity at human P2Y2Agonist activity at human P2Y2	ChEMBL	773	14	9	21	-2.9	Nc1ccn(c(=O)n1)[C@@H]1O[C@@H]([C@H](C1)O)COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1ccc(=O)[nH]c1=O)O)O)O)O	10.1021/acs.jmedchem.5b01972
	CHEMBL507282	1367	None	7	Human	Binding	pEC50	=	6.7	6.7	-	0	Agonist activity at human P2Y2Agonist activity at human P2Y2	ChEMBL	773	14	9	21	-2.9	Nc1ccn(c(=O)n1)[C@@H]1O[C@@H]([C@H](C1)O)COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1ccc(=O)[nH]c1=O)O)O)O)O	10.1021/acs.jmedchem.5b01972
	DB04983	1367	None	7	Human	Binding	pEC50	=	6.7	6.7	-	0	Agonist activity at human P2Y2Agonist activity at human P2Y2	ChEMBL	773	14	9	21	-2.9	Nc1ccn(c(=O)n1)[C@@H]1O[C@@H]([C@H](C1)O)COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1ccc(=O)[nH]c1=O)O)O)O)O	10.1021/acs.jmedchem.5b01972
	1713	520	None	42	Human	Binding	pEC50	=	6.6	6.6	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/acs.jmedchem.5b01972
	5957	520	None	42	Human	Binding	pEC50	=	6.6	6.6	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/acs.jmedchem.5b01972
	91	520	None	42	Human	Binding	pEC50	=	6.6	6.6	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/acs.jmedchem.5b01972
	CHEMBL14249	520	None	42	Human	Binding	pEC50	=	6.6	6.6	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/acs.jmedchem.5b01972
	DB00171	520	None	42	Human	Binding	pEC50	=	6.6	6.6	-	2	Agonist activity at human P2Y2 transfected in human 1321N1 cellsAgonist activity at human P2Y2 transfected in human 1321N1 cells	ChEMBL	507	8	7	14	-1.6	O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N	10.1021/acs.jmedchem.5b01972
	90656231	110981	None	0	Human	Binding	pEC50	=	6.4	6.4	-	0	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells by functional assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells by functional assay	ChEMBL	923	19	10	22	-2.1	O=c1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n4cc/c(=N/OCCCc5ccccc5)[nH]c4=O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c(=O)[nH]1	10.1021/jm500367e
	CHEMBL3261379	110981	None	0	Human	Binding	pEC50	=	6.4	6.4	-	0	Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells by functional assayAgonist activity at human P2Y2 receptor expressed in human 1321N1 cells by functional assay	ChEMBL	923	19	10	22	-2.1	O=c1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n4cc/c(=N/OCCCc5ccccc5)[nH]c4=O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c(=O)[nH]1	10.1021/jm500367e
	68077	207146	None	63	Mouse	Binding	pIC50	=	4.9	4.9	-	2	Antagonist activity at mouse P2Y2Antagonist activity at mouse P2Y2	ChEMBL	372	6	0	7	3.5	COc1ccc(-c2cc(=O)c3c(OC)c(OC)c(OC)c(OC)c3o2)cc1	10.1021/acs.jmedchem.5b01972
	CHEMBL73930	207146	None	63	Mouse	Binding	pIC50	=	4.9	4.9	-	2	Antagonist activity at mouse P2Y2Antagonist activity at mouse P2Y2	ChEMBL	372	6	0	7	3.5	COc1ccc(-c2cc(=O)c3c(OC)c(OC)c(OC)c(OC)c3o2)cc1	10.1021/acs.jmedchem.5b01972
	145962035	161706	None	0	Human	Binding	pKd	=	4.9	4.9	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	776	11	4	9	5.8	Cc1cc(C)n2c1C=C1C=CC(CCC(=O)NCCNC(=O)CCNc3nc4c(s3)C=Cc3cc(Cl)ccc3C4c3cn(C)c(=O)[nH]c3=S)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	CHEMBL4129692	161706	None	0	Human	Binding	pKd	=	4.9	4.9	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	776	11	4	9	5.8	Cc1cc(C)n2c1C=C1C=CC(CCC(=O)NCCNC(=O)CCNc3nc4c(s3)C=Cc3cc(Cl)ccc3C4c3cn(C)c(=O)[nH]c3=S)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	145963055	161629	None	0	Human	Binding	pKd	=	6.9	6.9	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1241	24	7	18	8.6	O=C(CCCCCNC(=O)COc1ccc(/C=C/C2=[N+]3C(=Cc4ccc(-c5cccs5)n4[B-]3(F)F)C=C2)cc1)NCCNC(=O)CCNc1nc2c(s1)C=Cc1cc(Cl)ccc1C2c1cn(Cc2nc(C(=O)Nc3nnn[nH]3)cs2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	CHEMBL4128532	161629	None	0	Human	Binding	pKd	=	6.9	6.9	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1241	24	7	18	8.6	O=C(CCCCCNC(=O)COc1ccc(/C=C/C2=[N+]3C(=Cc4ccc(-c5cccs5)n4[B-]3(F)F)C=C2)cc1)NCCNC(=O)CCNc1nc2c(s1)C=Cc1cc(Cl)ccc1C2c1cn(Cc2nc(C(=O)Nc3nnn[nH]3)cs2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	145962783	161532	None	0	Human	Binding	pKd	=	5.8	5.8	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1180	21	6	13	9.0	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)NCCNC(=O)CCCCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(C=C4)Cc4ccc(-c6cccs6)n4[B-]5(F)F)cc3)cc(C(=O)Nc3nnn[nH]3)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	CHEMBL4127230	161532	None	0	Human	Binding	pKd	=	5.8	5.8	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1180	21	6	13	9.0	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)NCCNC(=O)CCCCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(C=C4)Cc4ccc(-c6cccs6)n4[B-]5(F)F)cc3)cc(C(=O)Nc3nnn[nH]3)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	145962823	161615	None	0	Human	Binding	pKd	=	5.7	5.7	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	889	17	5	10	6.4	Cc1cc(C)n2c1C=C1C=CC(CCC(=O)NCCCCCC(=O)NCCNC(=O)CCNc3nc4c(s3)C=Cc3cc(Cl)ccc3C4c3cn(C)c(=O)[nH]c3=S)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	CHEMBL4128318	161615	None	0	Human	Binding	pKd	=	5.7	5.7	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	889	17	5	10	6.4	Cc1cc(C)n2c1C=C1C=CC(CCC(=O)NCCCCCC(=O)NCCNC(=O)CCNc3nc4c(s3)C=Cc3cc(Cl)ccc3C4c3cn(C)c(=O)[nH]c3=S)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	145961060	161514	None	0	Human	Binding	pKd	=	5.6	5.6	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1065	15	5	12	8.8	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)NCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(=Cc6ccc(-c7cccs7)n6[B-]5(F)F)C=C4)cc3)cc(C(=O)Nc3nnn[nH]3)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	CHEMBL4126826	161514	None	0	Human	Binding	pKd	=	5.6	5.6	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1065	15	5	12	8.8	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)NCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(=Cc6ccc(-c7cccs7)n6[B-]5(F)F)C=C4)cc3)cc(C(=O)Nc3nnn[nH]3)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	145962183	161592	None	0	Human	Binding	pKd	=	6.5	6.5	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	526	5	3	5	5.2	Cc1ccc2c(c1)CCc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)O)cc(C(=O)O)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	CHEMBL4128024	161592	None	0	Human	Binding	pKd	=	6.5	6.5	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	526	5	3	5	5.2	Cc1ccc2c(c1)CCc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)O)cc(C(=O)O)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	145961793	161670	None	0	Human	Binding	pKd	=	5.4	5.4	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	977	23	5	12	6.5	Cc1cc(C)n2c1C=C1C=CC(CCC(=O)NCCCCCC(=O)NCCOCCOCCNC(=O)CCNc3nc4c(s3)C=Cc3cc(Cl)ccc3C4c3cn(C)c(=O)[nH]c3=S)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	CHEMBL4129129	161670	None	0	Human	Binding	pKd	=	5.4	5.4	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	977	23	5	12	6.5	Cc1cc(C)n2c1C=C1C=CC(CCC(=O)NCCCCCC(=O)NCCOCCOCCNC(=O)CCNc3nc4c(s3)C=Cc3cc(Cl)ccc3C4c3cn(C)c(=O)[nH]c3=S)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	145961053	161502	None	0	Human	Binding	pKd	=	6.3	6.3	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1185	23	7	16	8.0	Cc1cc(C)n2c1C=C1C=CC(/C=C/c3ccc(CCC(=O)NCCCCCC(=O)NCCNC(=O)CCNc4nc5c(s4)C=Cc4cc(Cl)ccc4C5c4cn(Cc5nc(C(=O)Nc6nnn[nH]6)cs5)c(=O)[nH]c4=S)cc3)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	CHEMBL4126655	161502	None	0	Human	Binding	pKd	=	6.3	6.3	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1185	23	7	16	8.0	Cc1cc(C)n2c1C=C1C=CC(/C=C/c3ccc(CCC(=O)NCCCCCC(=O)NCCNC(=O)CCNc4nc5c(s4)C=Cc4cc(Cl)ccc4C5c4cn(Cc5nc(C(=O)Nc6nnn[nH]6)cs5)c(=O)[nH]c4=S)cc3)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	145961148	161680	None	0	Human	Binding	pKd	=	5.3	5.3	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1137	26	5	14	8.5	Cn1cc(C2c3ccc(Cl)cc3C=Cc3sc(NCCC(=O)NCCOCCOCCNC(=O)CCCCCNC(=O)COc4ccc(/C=C/C5=[N+]6C(C=C5)Cc5ccc(-c7cccs7)n5[B-]6(F)F)cc4)nc32)c(=S)[nH]c1=O	10.1021/acs.jmedchem.8b00139
	CHEMBL4129299	161680	None	0	Human	Binding	pKd	=	5.3	5.3	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1137	26	5	14	8.5	Cn1cc(C2c3ccc(Cl)cc3C=Cc3sc(NCCC(=O)NCCOCCOCCNC(=O)CCCCCNC(=O)COc4ccc(/C=C/C5=[N+]6C(C=C5)Cc5ccc(-c7cccs7)n5[B-]6(F)F)cc4)nc32)c(=S)[nH]c1=O	10.1021/acs.jmedchem.8b00139
	145962951	161440	None	0	Human	Binding	pKd	=	6.1	6.1	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1153	21	5	14	8.8	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)NCCOCCOCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(=Cc6ccc(-c7cccs7)n6[B-]5(F)F)C=C4)cc3)cc(C(=O)Nc3nnn[nH]3)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	CHEMBL4125853	161440	None	0	Human	Binding	pKd	=	6.1	6.1	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1153	21	5	14	8.8	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)NCCOCCOCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(=Cc6ccc(-c7cccs7)n6[B-]5(F)F)C=C4)cc3)cc(C(=O)Nc3nnn[nH]3)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	145961026	161447	None	0	Human	Binding	pKd	=	6.1	6.1	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1268	27	6	15	9.0	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)NCCOCCOCCNC(=O)CCCCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(C=C4)Cc4ccc(-c6cccs6)n4[B-]5(F)F)cc3)cc(C(=O)Nc3nnn[nH]3)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	CHEMBL4125987	161447	None	0	Human	Binding	pKd	=	6.1	6.1	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1268	27	6	15	9.0	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)NCCOCCOCCNC(=O)CCCCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(C=C4)Cc4ccc(-c6cccs6)n4[B-]5(F)F)cc3)cc(C(=O)Nc3nnn[nH]3)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	145960452	161584	None	0	Human	Binding	pKd	=	7.1	7.1	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	970	15	6	15	5.5	Cc1cc(C)n2c1C=C1C=CC(CCC(=O)NCCNC(=O)CCNc3nc4c(s3)C=Cc3cc(Cl)ccc3C4c3cn(Cc4nc(C(=O)Nc5nnn[nH]5)cs4)c(=O)[nH]c3=S)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	CHEMBL4127889	161584	None	0	Human	Binding	pKd	=	7.1	7.1	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	970	15	6	15	5.5	Cc1cc(C)n2c1C=C1C=CC(CCC(=O)NCCNC(=O)CCNc3nc4c(s3)C=Cc3cc(Cl)ccc3C4c3cn(Cc4nc(C(=O)Nc5nnn[nH]5)cs4)c(=O)[nH]c3=S)=[N+]1[B-]2(F)F	10.1021/acs.jmedchem.8b00139
	145962507	161436	None	0	Human	Binding	pKd	=	6.1	6.1	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1128	18	6	17	7.9	O=C(CCNc1nc2c(s1)C=Cc1cc(Cl)ccc1C2c1cn(Cc2nc(C(=O)Nc3nnn[nH]3)cs2)c(=O)[nH]c1=S)NCCNC(=O)COc1ccc(/C=C/C2=[N+]3C(=Cc4ccc(-c5cccs5)n4[B-]3(F)F)C=C2)cc1	10.1021/acs.jmedchem.8b00139
	CHEMBL4125833	161436	None	0	Human	Binding	pKd	=	6.1	6.1	-	1	Binding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assayBinding affinity to recombinant human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr in presence of AR-C118925 by furimazine-based NanoBRET assay	ChEMBL	1128	18	6	17	7.9	O=C(CCNc1nc2c(s1)C=Cc1cc(Cl)ccc1C2c1cn(Cc2nc(C(=O)Nc3nnn[nH]3)cs2)c(=O)[nH]c1=S)NCCNC(=O)COc1ccc(/C=C/C2=[N+]3C(=Cc4ccc(-c5cccs5)n4[B-]3(F)F)C=C2)cc1	10.1021/acs.jmedchem.8b00139
	145962594	161600	None	0	Human	Binding	pKi	=	6.9	6.9	-	1	Displacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assayDisplacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assay	ChEMBL	554	5	3	9	4.5	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2nc(C(=O)Nc3nnn[nH]3)cs2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	CHEMBL4128126	161600	None	0	Human	Binding	pKi	=	6.9	6.9	-	1	Displacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assayDisplacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assay	ChEMBL	554	5	3	9	4.5	Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2nc(C(=O)Nc3nnn[nH]3)cs2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	145962183	161592	None	0	Human	Binding	pKi	=	6.8	6.8	-	1	Displacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assayDisplacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assay	ChEMBL	526	5	3	5	5.2	Cc1ccc2c(c1)CCc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)O)cc(C(=O)O)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	CHEMBL4128024	161592	None	0	Human	Binding	pKi	=	6.8	6.8	-	1	Displacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assayDisplacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assay	ChEMBL	526	5	3	5	5.2	Cc1ccc2c(c1)CCc1cc(C)ccc1C2c1cn(Cc2cc(C(=O)O)cc(C(=O)O)c2)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	88151531	161587	None	0	Human	Binding	pKi	=	5.8	5.8	-	1	Displacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assayDisplacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assay	ChEMBL	387	1	1	5	4.5	Cc1nc2c(s1)C=Cc1cc(Cl)ccc1C2c1cn(C)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139
	CHEMBL4127983	161587	None	0	Human	Binding	pKi	=	5.8	5.8	-	1	Displacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assayDisplacement of (E)-2-((5-(7-Chloro-2-((3-((2-(6-(3-(5,5-difluoro-7,9-dimethyl-5H-5-lambda4,6-lambda4-dipyrrolo[1,2-c:2,1-f ][1,3,2]diazaborinin-3-yl)-propanamido)hexanamido)ethyl)amino)-3-oxopropyl)amino)-4Hbenzo[5,6]cyclohepta[1,2-d]thiazol-4-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)thiazole-4-carboxamide from human N-terminal NLuc-tagged P2Y2R expressed in human 1321N1 cells incubated for 1 hr by furimazine-based NanoBRET assay	ChEMBL	387	1	1	5	4.5	Cc1nc2c(s1)C=Cc1cc(Cl)ccc1C2c1cn(C)c(=O)[nH]c1=S	10.1021/acs.jmedchem.8b00139

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Ligand source activities (1 row/activity)