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Ligand source activities (1 row/activity)

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Potency

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

[Ac-Tyr¹, D-Arg²]GHRH-(1-29)-NH₂ (human)	281	None	0	Rat	Binding	pKi	None	-	8.40	-	1	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9892695
[Ac-Tyr¹, D-Arg²]GHRH-(1-29)-NH₂ (human)	281	None	0	Rat	Binding	pKi	None	-	8.40	-	1	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/14755056
[Ac-Tyr¹, D-Arg²]GHRH-(1-29)-NH₂ (human)	281	None	0	Rat	Binding	pKi	None	-	8.40	-	1	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/7991622
[Ac-Tyr¹, D-Arg²]GHRH-(1-29)-NH₂ (human)	281	None	0	Rat	Binding	pKi	None	-	8.40	-	1	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9145431
CHEMBL216479	81926	None	0	Rat	Binding	IC50	=	6.60	8.18	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	3468.9	121	50	48	-14.30	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL262536	212999	None	0	Rat	Binding	IC50	=	45.20	7.34	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL262750	96574	None	0	Rat	Binding	IC50	=	13.70	7.86	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	3440.9	119	50	48	-15.08	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL264522	213083	None	0	Rat	Binding	IC50	=	120.00	6.92	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL265167	213099	None	15	Rat	Binding	IC50	=	9.80	8.01	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL266658	213150	None	0	Rat	Binding	IC50	=	9.50	8.02	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL269041	213235	None	0	Rat	Binding	IC50	=	217.00	6.66	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	-	https://dx.doi.org/10.1021/jm00088a023
CHEMBL269263	213242	None	0	Rat	Binding	IC50	=	1000.00	6.00	-	1	Compound was tested to Inhibit [125I]GRF in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL385308	214808	None	0	Rat	Binding	IC50	=	1.90	8.72	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL386366	141913	None	0	Rat	Binding	IC50	=	0.73	9.14	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	3353.8	116	47	46	-12.44	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)CC(=O)CCc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL411913	161337	None	0	Rat	Binding	IC50	=	130.00	6.89	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	3135.8	108	44	42	-11.15	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)CC(=O)CCc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL412221	215437	None	0	Rat	Binding	IC50	=	1000.00	6.00	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL412558	215463	None	0	Rat	Binding	IC50	=	95.00	7.02	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL413014	215504	None	0	Rat	Binding	IC50	=	17.60	7.75	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL414943	215623	None	0	Rat	Binding	IC50	=	20.20	7.70	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023
CHEMBL415373	215646	None	0	Rat	Binding	IC50	=	836.00	6.08	-	1	Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates	ChEMBL	-	-	-	-	-	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O)[C@@H](C)CC)C(C)C)[C@@H](C)O	https://dx.doi.org/10.1021/jm00088a023

Showing 1 to 20 of 54 entries

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

CHEMBL1189066	12918	None	0	Rat	Functional	EC50	=	1.30	8.89	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	547.3	11	2	5	4.62	CCOC(=O)CCC1CC2(CCN(C(=O)[C@@H](CCCc3ccccc3)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1189070	12919	None	0	Rat	Functional	EC50	=	1.00	9.00	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	533.3	10	2	5	4.23	CCOC(=O)C[C@H]1CC2(CCN(C(=O)[C@@H](CCCc3ccccc3)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1190394	13113	None	0	Rat	Functional	EC50	=	2.50	8.60	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	519.3	10	3	4	4.14	CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(CC1)CC(CCC(=O)O)c1ccccc12	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1190399	13114	None	0	Rat	Functional	EC50	=	2.30	8.64	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	505.3	9	3	4	3.75	CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(CC1)C[C@H](CC(=O)O)c1ccccc12	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1193173	13468	None	0	Rat	Functional	EC50	=	2.90	8.54	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	521.3	9	2	6	3.04	CCOC(=O)[C@H]1CC2(CCN(C(=O)[C@@H](COCc3ccccc3)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1193375	13496	None	0	Rat	Functional	EC50	=	2.00	8.70	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	519.3	9	2	5	3.84	CCOC(=O)[C@@H]1CC2(CCN(C(=O)[C@@H](CCCc3ccccc3)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1193573	13515	None	0	Rat	Functional	EC50	=	0.80	9.10	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	533.3	10	2	5	4.23	CCOC(=O)C[C@@H]1CC2(CCN(C(=O)[C@@H](CCCc3ccccc3)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1193574	13516	None	0	Rat	Functional	EC50	=	4.40	8.36	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	493.3	8	3	5	2.56	CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CC1)C[C@H](C(=O)O)c1ccccc12	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1194179	13609	None	0	Rat	Functional	EC50	=	2.10	8.68	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	491.3	8	3	4	3.36	CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(CC1)C[C@H](C(=O)O)c1ccccc12	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1194442	13643	None	0	Rat	Functional	EC50	=	7.00	8.15	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	544.3	8	3	5	3.93	CCOC(=O)C[C@@H]1CC2(CCN(C(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1194592	13663	None	0	Rat	Functional	EC50	=	6.60	8.18	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	521.3	9	2	6	3.04	CCOC(=O)[C@@H]1CC2(CCN(C(=O)[C@@H](COCc3ccccc3)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1194776	13689	None	0	Rat	Functional	EC50	=	2.50	8.60	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	491.3	8	3	4	3.36	CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(CC1)C[C@@H](C(=O)O)c1ccccc12	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1194874	13703	None	0	Rat	Functional	EC50	=	1.90	8.72	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	505.3	9	3	4	3.75	CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(CC1)C[C@@H](CC(=O)O)c1ccccc12	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1194891	13705	None	0	Rat	Functional	EC50	=	6.00	8.22	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	530.3	7	3	5	3.54	CCOC(=O)[C@H]1CC2(CCN(C(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1195548	13799	None	0	Rat	Functional	EC50	=	28.00	7.55	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	544.3	8	3	5	3.93	CCOC(=O)C[C@H]1CC2(CCN(C(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1196053	13878	None	0	Rat	Functional	EC50	=	8.30	8.08	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	530.3	7	3	5	3.54	CCOC(=O)[C@@H]1CC2(CCN(C(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL1196866	13983	None	0	Rat	Functional	EC50	=	5.80	8.24	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	516.3	7	4	4	3.46	CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC2(CC1)C[C@@H](CC(=O)O)c1ccccc12	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL294923	101142	None	0	Rat	Functional	EC50	=	10.00	8.00	-1	2	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	447.3	7	2	3	3.74	CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(CCc3ccccc32)CC1	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL319460	108082	None	0	Rat	Functional	EC50	=	1.00	9.00	-	1	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	519.3	9	2	5	3.84	CCOC(=O)[C@H]1CC2(CCN(C(=O)[C@@H](CCCc3ccccc3)NC(=O)C(C)(C)N)CC2)c2ccccc21	https://dx.doi.org/10.1016/S0960-894X(97)00421-6
CHEMBL417182	162864	None	0	Rat	Functional	EC50	=	17.00	7.77	-1	2	Ability to release growth hormone in a rat pituitary cell assay	ChEMBL	449.3	7	2	4	2.93	CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CCc3ccccc32)CC1	https://dx.doi.org/10.1016/S0960-894X(97)00421-6

Showing 1 to 20 of 29 entries