BLT1 receptor (q9wtk1_cavpo)

FAMILY

Class A (Rhodopsin) Lipid receptors Leukotriene receptors BLT1 receptor

GENE

LTB4R

ORGANISM

Guinea pig (Cavia porcellus)

ALT. NAMES

LTB4 receptor, Leukotriene B4 receptor

SOURCE

TREMBL

SEQUENCE

N-term        
M
D
R
N
T
T
T
R
A
A
10
            TM1  
S
P
S
G
S
N
T
F
I
P
20
                   
L
L
A
M
I
L
L
S
V
S
30
                   
M
V
V
G
L
P
G
N
T
F
40
                   
V
V
W
S
I
L
K
R
M
R
50
ICL1 TM2      
K
R
S
V
T
A
L
M
V
L
60
                   
N
L
A
L
A
D
L
A
V
L
70
                   
L
T
A
P
F
F
L
H
F
L
80
      ECL1 TM3
T
W
H
T
W
S
F
K
L
A
90
                   
G
C
R
L
C
H
Y
I
C
G
100
                   
V
S
M
Y
A
S
V
L
L
I
110
                   
T
A
M
S
L
D
R
S
L
A
120
      ICL2      
V
A
S
P
F
L
S
Q
K
V
130
  TM4            
R
T
K
T
A
A
R
W
L
L
140
                   
V
G
I
W
G
A
S
F
L
L
150
                   
A
T
P
V
L
A
F
R
K
V
160
ECL2            
V
K
L
T
N
E
T
D
L
C
170
          TM5    
L
A
V
Y
P
S
D
R
H
K
180
                   
A
F
H
L
L
F
E
A
F
T
190
                   
G
F
V
V
P
F
L
I
V
V
200
                   
A
S
Y
A
D
I
S
R
R
L
210
      ICL3 TM6
R
V
R
R
F
H
R
R
R
R
220
                   
T
G
R
L
V
V
I
I
I
L
230
                   
A
F
A
A
F
W
L
P
Y
H
240
                   
V
V
D
L
V
E
G
S
R
V
250
    ECL3   TM7
L
A
G
T
L
D
Q
S
K
Q
260
                   
Q
L
R
N
A
R
K
V
C
I
270
                   
A
L
A
F
L
S
S
S
V
N
280
                   
P
L
L
Y
A
C
A
G
G
G
290
                   
L
L
R
S
A
G
V
G
F
V
300
C-term        
A
K
L
L
E
A
T
G
S
E
310
                   
A
F
S
T
R
R
G
G
T
L
320
                   
A
Q
T
V
K
G
I
P
M
A
330
                   
P
E
P
G
A
S
G
S
L
D
340
               
G
L
K
Q
S
E
S
D

LINKS

DIAGRAMS

ICL1 M R K R ICL1ECL1 T W S F ECL1ICL2 P F L S Q K V R ICL2ECL2 K V V K L T N E T D L C L A V Y P ECL2ICL3 R F H R ICL3ECL3 G T L D Q ECL3N-term M D R N T T T R A A S P S G S N N-termC-term G V G F V A K L L E A T G S E A F S T R R G G T L A Q T V K G I P M A P E P G A S G S L D G L K Q S E S D C-term T F I P L L A M I L L S V S M V V G L P G N T F V V W S I L K R S V T A L M V L N L A L A D L A V L L T A P F F L H F L T W H K L A G C R L C H Y I C G V S M Y A S V L L I T A M S L D R S L A V A S T K T A A R W L L V G I W G A S F L L A T P V L A F R S D R H K A F H L L F E A F T G F V V P F L I V V A S Y A D I S R R L R V R R R R T G R L V V I I I L A F A A F W L P Y H V V D L V E G S R V L A S K Q Q L R N A R K V C I A L A F L S S S V N P L L Y A C A G G G L L R S A
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

T N G P L G V V M S V S L L I M A L L P 1 L N L A L A D L A V L L T A P F F L H F 2 A T I L L V S A Y M S V G C I Y H C L R 3 A R W L L V G I W G A S F L L A T P V 4 Y S A V V I L F P V V F G T F A E F L L H 5 V I I I L A F A A F W L P Y H V V D L V 6 L P N V S S S L F A L A I C V K R A N 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

No structure models have been generated as experimental structures are available (see below).

STRUCTURES

Found 1 structure(s) - view all details on the Structures page

PDBs: 5X33