GPCRdb

5DSG refined

GPCR CLASS

Class A (Rhodopsin)

RECEPTOR

M₄ receptor

SPECIES

Homo sapiens

STATE

Inactive

VERSION

2022-10-26

METHOD

AlphaFold2

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of Cα atoms

NGL is a WebGL based 3D viewer powered by MMTF.

MAIN TEMPLATE

M₄ receptor (sequence similarity: 100%) PDB: 5DSG

TEMPLATES

5DSG (M₄ receptor)

AlphaFold

	Main template (%)	AlphaFold (%)
Backbone	59.5	40.5
Side-chains	58.5	41.5

Segment	Seq.num.	AA	GPCRdb#	Backbone	PDB	Rotamer	PDB

N-term	1	M	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	2	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	3	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	4	F	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	5	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	6	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	7	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	8	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	9	G	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	10	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	11	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	12	G	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	13	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	14	Q	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	15	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	16	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	17	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	18	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	19	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	20	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	21	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	22	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	23	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	24	H	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
N-term	25	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
TM1	26	R	1.26x26	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	27	Y	1.27x27	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	28	E	1.28x28	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	29	T	1.29x29	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	30	V	1.30x30	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	31	E	1.31x31	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	32	M	1.32x32	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	33	V	1.33x33	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	34	F	1.34x34	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	35	I	1.35x35	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	36	A	1.36x36	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	37	T	1.37x37	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	38	V	1.38x38	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	39	T	1.39x39	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	40	G	1.40x40	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	41	S	1.41x41	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	42	L	1.42x42	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	43	S	1.43x43	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	44	L	1.44x44	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	45	V	1.45x45	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	46	T	1.46x46	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	47	V	1.47x47	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	48	V	1.48x48	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	49	G	1.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	50	N	1.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	51	I	1.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	52	L	1.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	53	V	1.53x53	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	54	M	1.54x54	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	55	L	1.55x55	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	56	S	1.56x56	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	57	I	1.57x57	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	58	K	1.58x58	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	59	V	1.59x59	M₄ receptor	5DSG	M₄ receptor	5DSG
TM1	60	N	1.60x60	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL1	61	R	12.48x48	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL1	62	Q	12.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL1	63	L	12.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL1	64	Q	12.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	65	T	2.37x37	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	66	V	2.38x38	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	67	N	2.39x39	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	68	N	2.40x40	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	69	Y	2.41x41	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	70	F	2.42x42	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	71	L	2.43x43	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	72	F	2.44x44	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	73	S	2.45x45	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	74	L	2.46x46	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	75	A	2.47x47	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	76	C	2.48x48	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	77	A	2.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	78	D	2.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	79	L	2.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	80	I	2.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	81	I	2.53x53	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	82	G	2.54x54	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	83	A	2.55x55	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	84	F	2.56x551	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	85	S	2.57x56	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	86	M	2.58x57	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	87	N	2.59x58	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	88	L	2.60x59	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	89	Y	2.61x60	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	90	T	2.62x61	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	91	V	2.63x62	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	92	Y	2.64x63	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	93	I	2.65x64	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	94	I	2.66x65	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	95	K	2.67x66	M₄ receptor	5DSG	M₄ receptor	5DSG
TM2	96	G	2.68x67	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL1	97	Y	23.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL1	98	W	23.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL1	99	P	23.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL1	100	L	23.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	101	G	3.21x21	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	102	A	3.22x22	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	103	V	3.23x23	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	104	V	3.24x24	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	105	C	3.25x25	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	106	D	3.26x26	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	107	L	3.27x27	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	108	W	3.28x28	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	109	L	3.29x29	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	110	A	3.30x30	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	111	L	3.31x31	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	112	D	3.32x32	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	113	Y	3.33x33	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	114	V	3.34x34	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	115	V	3.35x35	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	116	S	3.36x36	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	117	N	3.37x37	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	118	A	3.38x38	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	119	S	3.39x39	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	120	V	3.40x40	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	121	M	3.41x41	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	122	N	3.42x42	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	123	L	3.43x43	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	124	L	3.44x44	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	125	I	3.45x45	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	126	I	3.46x46	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	127	S	3.47x47	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	128	F	3.48x48	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	129	D	3.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	130	R	3.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	131	Y	3.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	132	F	3.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	133	C	3.53x53	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	134	V	3.54x54	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	135	T	3.55x55	M₄ receptor	5DSG	M₄ receptor	5DSG
TM3	136	K	3.56x56	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL2	137	P	34.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL2	138	L	34.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL2	139	T	34.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL2	140	Y	34.53x53	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL2	141	P	34.54x54	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL2	142	A	34.55x55	M₄ receptor	5DSG	M₄ receptor	5DSG
ICL2	143	R	34.56x56	M₄ receptor	5DSG	AlphaFold	AlphaFold
ICL2	144	R	34.57x57	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	145	T	4.38x38	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	146	T	4.39x39	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	147	K	4.40x40	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	148	M	4.41x41	M₄ receptor	5DSG	AlphaFold	AlphaFold
TM4	149	A	4.42x42	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	150	G	4.43x43	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	151	L	4.44x44	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	152	M	4.45x45	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	153	I	4.46x46	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	154	A	4.47x47	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	155	A	4.48x48	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	156	A	4.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	157	W	4.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	158	V	4.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	159	L	4.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	160	S	4.53x53	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	161	F	4.54x54	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	162	V	4.55x55	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	163	L	4.56x56	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	164	W	4.57x57	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	165	A	4.58x58	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	166	P	4.59x59	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	167	A	4.60x60	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	168	I	4.61x61	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	169	L	4.62x62	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	170	F	4.63x63	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	171	W	4.64x64	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	172	Q	4.65x65	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	173	F	4.66x66	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	174	V	4.67x67	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	175	V	4.68x68	M₄ receptor	5DSG	M₄ receptor	5DSG
TM4	176	G	4.69x69	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	177	K	-	M₄ receptor	5DSG	AlphaFold	AlphaFold
ECL2	178	R	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	179	T	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	180	V	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	181	P	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	182	D	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	183	N	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	184	Q	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	185	C	45.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	186	F	45.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	187	I	45.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	188	Q	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	189	F	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	190	L	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL2	191	S	-	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	192	N	5.35x36	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	193	P	5.36x37	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	194	A	5.37x38	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	195	V	5.38x39	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	196	T	5.39x40	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	197	F	5.40x41	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	198	G	5.41x42	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	199	T	5.42x43	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	200	A	5.43x44	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	201	I	5.44x45	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	202	A	5.45x46	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	203	A	5.46x461	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	204	F	5.47x47	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	205	Y	5.48x48	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	206	L	5.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	207	P	5.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	208	V	5.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	209	V	5.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	210	I	5.53x53	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	211	M	5.54x54	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	212	T	5.55x55	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	213	V	5.56x56	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	214	L	5.57x57	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	215	Y	5.58x58	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	216	I	5.59x59	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	217	H	5.60x60	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	218	I	5.61x61	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	219	S	5.62x62	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	220	L	5.63x63	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	221	A	5.64x64	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	222	S	5.65x65	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	223	R	5.66x66	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	224	S	5.67x67	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	225	R	5.68x68	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	226	V	5.69x69	M₄ receptor	5DSG	M₄ receptor	5DSG
TM5	227	H	5.70x70	AlphaFold	AlphaFold	AlphaFold	AlphaFold
TM5	228	K	5.71x71	AlphaFold	AlphaFold	AlphaFold	AlphaFold
TM5	229	H	5.72x72	AlphaFold	AlphaFold	AlphaFold	AlphaFold
TM5	230	R	5.73x73	AlphaFold	AlphaFold	AlphaFold	AlphaFold
TM5	231	P	5.74x74	AlphaFold	AlphaFold	AlphaFold	AlphaFold
TM5	232	E	5.75x75	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	233	G	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	234	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	235	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	236	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	237	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	238	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	239	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	240	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	241	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	242	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	243	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	244	F	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	245	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	246	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	247	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	248	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	249	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	250	M	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	251	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	252	Q	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	253	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	254	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	255	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	256	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	257	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	258	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	259	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	260	G	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	261	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	262	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	263	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	264	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	265	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	266	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	267	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	268	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	269	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	270	G	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	271	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	272	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	273	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	274	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	275	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	276	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	277	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	278	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	279	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	280	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	281	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	282	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	283	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	284	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	285	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	286	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	287	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	288	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	289	D	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	290	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	291	D	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	292	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	293	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	294	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	295	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	296	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	297	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	298	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	299	G	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	300	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	301	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	302	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	303	Q	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	304	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	305	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	306	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	307	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	308	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	309	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	310	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	311	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	312	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	313	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	314	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	315	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	316	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	317	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	318	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	319	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	320	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	321	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	322	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	323	M	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	324	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	325	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	326	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	327	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	328	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	329	Q	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	330	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	331	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	332	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	333	L	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	334	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	335	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	336	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	337	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	338	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	339	W	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	340	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	341	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	342	I	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	343	Q	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	344	I	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	345	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	346	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	347	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	348	Q	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	349	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	350	G	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	351	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	352	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	353	C	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	354	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	355	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	356	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	357	I	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	358	E	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	359	I	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	360	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	361	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	362	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	363	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	364	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	365	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	366	G	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	367	M	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	368	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	369	P	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	370	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	371	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	372	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	373	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	374	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	375	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	376	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	377	F	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	378	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	379	S	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	380	I	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	381	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	382	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	383	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	384	Q	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	385	V	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	386	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	387	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
ICL3	388	K	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
TM6	389	R	6.24x24	AlphaFold	AlphaFold	AlphaFold	AlphaFold
TM6	390	Q	6.25x25	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	391	M	6.26x26	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	392	A	6.27x27	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	393	A	6.28x28	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	394	R	6.29x29	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	395	E	6.30x30	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	396	R	6.31x31	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	397	K	6.32x32	M₄ receptor	5DSG	AlphaFold	AlphaFold
TM6	398	V	6.33x33	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	399	T	6.34x34	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	400	R	6.35x35	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	401	T	6.36x36	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	402	I	6.37x37	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	403	F	6.38x38	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	404	A	6.39x39	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	405	I	6.40x40	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	406	L	6.41x41	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	407	L	6.42x42	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	408	A	6.43x43	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	409	F	6.44x44	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	410	I	6.45x45	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	411	L	6.46x46	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	412	T	6.47x47	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	413	W	6.48x48	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	414	T	6.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	415	P	6.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	416	Y	6.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	417	N	6.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	418	V	6.53x53	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	419	M	6.54x54	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	420	V	6.55x55	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	421	L	6.56x56	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	422	V	6.57x57	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	423	N	6.58x58	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	424	T	6.59x59	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	425	F	6.60x60	M₄ receptor	5DSG	M₄ receptor	5DSG
TM6	426	C	6.61x61	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL3	427	Q	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL3	428	S	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL3	429	C	-	M₄ receptor	5DSG	M₄ receptor	5DSG
ECL3	430	I	-	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	431	P	7.31x30	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	432	D	7.32x31	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	433	T	7.33x32	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	434	V	7.34x33	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	435	W	7.35x34	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	436	S	7.36x35	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	437	I	7.37x36	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	438	G	7.38x37	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	439	Y	7.39x38	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	440	W	7.40x39	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	441	L	7.41x40	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	442	C	7.42x41	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	443	Y	7.43x42	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	444	V	7.44x43	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	445	N	7.45x45	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	446	S	7.46x46	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	447	T	7.47x47	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	448	I	7.48x48	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	449	N	7.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	450	P	7.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	451	A	7.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	452	C	7.52x52	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	453	Y	7.53x53	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	454	A	7.54x54	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	455	L	7.55x55	M₄ receptor	5DSG	M₄ receptor	5DSG
TM7	456	C	7.56x56	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	457	N	8.47x47	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	458	A	8.48x48	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	459	T	8.49x49	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	460	F	8.50x50	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	461	K	8.51x51	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	462	K	8.52x52	M₄ receptor	5DSG	AlphaFold	AlphaFold
H8	463	T	8.53x53	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	464	F	8.54x54	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	465	R	8.55x55	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	466	H	8.56x56	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	467	L	8.57x57	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	468	L	8.58x58	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	469	L	8.59x59	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	470	C	8.60x60	M₄ receptor	5DSG	M₄ receptor	5DSG
H8	471	Q	8.61x61	M₄ receptor	5DSG	M₄ receptor	5DSG
C-term	472	Y	-	M₄ receptor	5DSG	M₄ receptor	5DSG
C-term	473	R	-	M₄ receptor	5DSG	M₄ receptor	5DSG
C-term	474	N	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
C-term	475	I	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
C-term	476	G	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
C-term	477	T	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
C-term	478	A	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold
C-term	479	R	-	AlphaFold	AlphaFold	AlphaFold	AlphaFold