GPCRdb

CHEMBL367367

Agent/drug
Bioactivity

CHEMBL367367

SMILES	Cc1cc(F)ccc1OC(CCN1CCC(n2c(O)nc3ccccc32)CC1)C(C)C
InChIKey	MDCJHLUPHKBLLO-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	425.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

μ	OPRM	Human	Opioid	A	pKi	7.42	7.42	7.42	ChEMBL
NOP	OPRX	Human	Opioid	A	pKi	7.50	7.50	7.50	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

NOP	OPRX	Human	Opioid	A	pIC50	5.01	5.01	5.01	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL367367

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.