GPCRdb

[Met]enkephalin

Agent/drug
Bioactivity

[Met]enkephalin

SMILES	None
InChIKey	YFGBQHOOROIVKG-FKBYEOEOSA-N
Sequence	YGGFM

Chemical Properties

Hydrogen bond acceptors	None
Hydrogen bond donors	None
Rotatable bonds	None
Molecular weight (Da)

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Rat	Opioid	A	pKi	8.14	8.14	8.14	ChEMBL
δ	OPRD	Human	Opioid	A	pKi	8.70	8.83	8.96	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pKi	5.35	5.35	5.35	ChEMBL
κ	OPRK	Rat	Opioid	A	pKi	6.00	6.00	6.00	Guide to Pharmacology
μ	OPRM	Rat	Opioid	A	pKi	9.20	9.20	9.20	Guide to Pharmacology
μ	OPRM	Rat	Opioid	A	pKi	7.56	7.63	7.70	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	7.72	8.27	8.82	ChEMBL
NOP	OPRX	Guinea pig	Opioid	A	pKi	6.56	6.56	6.56	ChEMBL

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Mouse	Opioid	A	pIC50	7.40	7.40	7.40	Guide to Pharmacology
δ	OPRD	Mouse	Opioid	A	pIC50	7.89	7.89	7.89	ChEMBL
δ	OPRD	Rat	Opioid	A	pIC50	9.00	9.00	9.00	ChEMBL
δ	OPRD	Human	Opioid	A	pEC50	7.33	8.44	8.99	ChEMBL
δ	OPRD	Human	Opioid	A	pIC50	8.19	8.19	8.19	ChEMBL
μ	OPRM	Rat	Opioid	A	pIC50	8.70	8.70	8.70	ChEMBL
μ	OPRM	Rat	Opioid	A	pEC50	6.51	6.51	6.52	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	6.21	6.58	6.96	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	7.89	7.89	7.89	ChEMBL

Showing 1 to 9 of 9 entries

[Met]enkephalin

Drug properties

Molecular type	Peptide
Physiological/Surrogate	Endogenous
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.