GPCRdb

neuropeptide FF

Agent/drug
Bioactivity

neuropeptide FF

SMILES	None
InChIKey	None
Sequence	FLFQPQRF

Chemical Properties

Hydrogen bond acceptors	None
Hydrogen bond donors	None
Rotatable bonds	None
Molecular weight (Da)

Database connections

Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

NPFF1	NPFF1	Human	Neuropeptide FF/neuropeptide AF	A	pKi	8.50	9.20	9.90	Guide to Pharmacology
NPFF1	NPFF1	Human	Neuropeptide FF/neuropeptide AF	A	pKi	10.22	10.22	10.22	ChEMBL
NPFF1	NPFF1	Human	Neuropeptide FF/neuropeptide AF	A	pKd	8.95	8.95	8.95	ChEMBL
NPFF2	NPFF2	Human	Neuropeptide FF/neuropeptide AF	A	pKi	9.70	9.70	9.70	Guide to Pharmacology
NPFF2	NPFF2	Mouse	Neuropeptide FF/neuropeptide AF	A	pKi	8.96	8.96	8.96	ChEMBL
NPFF2	NPFF2	Rat	Neuropeptide FF/neuropeptide AF	A	pKi	9.68	9.68	9.68	ChEMBL
NPFF2	NPFF2	Human	Neuropeptide FF/neuropeptide AF	A	pKi	8.92	9.81	10.70	ChEMBL
NPFF2	NPFF2	Human	Neuropeptide FF/neuropeptide AF	A	pKd	9.43	9.55	9.68	ChEMBL

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	6.92	6.92	6.92	ChEMBL
MAS1	MAS	Mouse	A orphans	A	pEC50	6.40	6.40	6.40	Guide to Pharmacology
NPFF1	NPFF1	Human	Neuropeptide FF/neuropeptide AF	A	pEC50	6.56	6.64	6.80	ChEMBL
NPFF2	NPFF2	Human	Neuropeptide FF/neuropeptide AF	A	pEC50	6.21	7.38	8.57	ChEMBL

Showing 1 to 4 of 4 entries

neuropeptide FF

Drug properties

Molecular type	Peptide
Physiological/Surrogate	Endogenous
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.