GPCRdb

(-)-noradrenaline

(-)-noradrenaline

SMILES	NC[C@@H](c1ccc(c(c1)O)O)O
InChIKey	SFLSHLFXELFNJZ-QMMMGPOBSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	4
Rotatable bonds	2
Molecular weight (Da)	169.1

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7EJ0
Ligand site mutations	α_1A α_1B α_2A α_2B β₂ β₃ D₄

Bioactivities

Affinity
Potency

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

(-)-noradrenaline

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	Yes

Clinical Trials

Phase I 9

Phase II 18

Phase III 18

Approved Yes

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7EJ0
Ligand site mutations	α_1A α_1B α_2A α_2B β₂ β₃ D₄

Sankey plot

Drug Information

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

This ligand is endogenous.