GPCRdb

noradrenaline

Agent/drug
Bioactivity

noradrenaline

SMILES	NCC(O)c1ccc(O)c(O)c1
InChIKey	SFLSHLFXELFNJZ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	4
Rotatable bonds	2
Molecular weight (Da)	169.1

Database connections

Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	β₁ β₂

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	Q9TSW7	Pig	Adrenoceptors	A	pKi	5.00	5.12	5.30	PDSP Ki database
α_1B	ADA1B	Human	Adrenoceptors	A	pKi	5.00	5.39	6.04	PDSP Ki database
α_1B	ADA1B	Rat	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
α_1B	A0A4X1U0M4	Pig	Adrenoceptors	A	pKi	5.60	5.60	5.60	PDSP Ki database
α_1D	ADA1D	Rat	Adrenoceptors	A	pKi	7.00	7.00	7.00	PDSP Ki database
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	5.00	5.03	5.06	PDSP Ki database
α_2A	ADA2A	Pig	Adrenoceptors	A	pKi	5.25	5.84	6.43	PDSP Ki database
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	5.70	6.03	6.40	PDSP Ki database
α_2A	ADA2A	Mouse	Adrenoceptors	A	pKi	5.85	5.85	5.85	PDSP Ki database
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	5.56	6.02	6.48	PDSP Ki database
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	5.87	6.05	6.23	PDSP Ki database
β₁	ADRB1	Human	Adrenoceptors	A	pKi	6.00	6.00	6.00	Guide to Pharmacology
β₁	ADRB1	Human	Adrenoceptors	A	pKi	5.45	5.45	5.45	PDSP Ki database
β₂	ADRB2	Human	Adrenoceptors	A	pKi	5.40	5.40	5.40	Guide to Pharmacology
β₂	ADRB2	Human	Adrenoceptors	A	pKi	5.00	5.27	6.10	PDSP Ki database
β₃	ADRB3	Human	Adrenoceptors	A	pKi	5.37	5.37	5.37	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	5.00	5.42	6.26	PDSP Ki database
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database

Showing 1 to 20 of 39 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TA₁	TAAR1	Human	Trace amine	A	pEC50	4.91	4.91	4.91	ChEMBL

Showing 1 to 1 of 1 entry

noradrenaline

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	β₁ β₂

Compound is not listed as a drug.