GPCRdb

N-palmitoylethanolamine

Agent/drug
Bioactivity

N-palmitoylethanolamine

SMILES	CCCCCCCCCCCCCCCC(=O)NCCO
InChIKey	HXYVTAGFYLMHSO-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	16
Molecular weight (Da)	299.3

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pKi	5.30	5.30	5.30	PDSP Ki database
CB₁	CNR1	Human	Cannabinoid	A	pKi	8.28	8.28	8.28	Drug Central
CB₂	CNR2	Human	Cannabinoid	A	pKi	8.28	8.28	8.28	Drug Central
CB₂	CNR2	Human	Cannabinoid	A	pKi	5.30	5.30	5.30	PDSP Ki database

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pEC50	8.08	8.08	8.08	Drug Central
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pEC50	8.40	8.40	8.40	Guide to Pharmacology
M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	7.05	7.05	7.05	ChEMBL

Showing 1 to 3 of 3 entries

N-palmitoylethanolamine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.