GPCRdb

octopamine

Agent/drug
Bioactivity

octopamine

SMILES	NCC(O)c1ccc(O)cc1
InChIKey	QHGUCRYDKWKLMG-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	3
Rotatable bonds	2
Molecular weight (Da)	153.1

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	α_2A

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₇	5HT7R	Rat	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	PDSP Ki database

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TA₁	TAAR1	Human	Trace amine	A	pEC50	4.80	5.30	5.80	Guide to Pharmacology
TA₁	TAAR1	Rat	Trace amine	A	pEC50	5.90	5.90	5.90	Guide to Pharmacology
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	5.40	5.60	5.80	Guide to Pharmacology
TA₁	TAAR1	Human	Trace amine	A	pEC50	8.24	8.24	8.24	Drug Central
TA₁	TAAR1	Rat	Trace amine	A	pEC50	8.23	8.23	8.23	Drug Central
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	8.24	8.24	8.24	Drug Central
TA₁	TAAR1	Rat	Trace amine	A	pEC50	5.89	5.89	5.89	ChEMBL

Showing 1 to 7 of 7 entries

octopamine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	α_2A

Compound is not listed as a drug.