GPCRdb

anandamide

Agent/drug
Bioactivity

anandamide

SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO
InChIKey	LGEQQWMQCRIYKG-DOFZRALJSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	16
Molecular weight (Da)	347.3

Database connections

Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pKi	6.30	6.65	7.00	Guide to Pharmacology
CB₁	CNR1	Mouse	Cannabinoid	A	pKi	5.27	6.16	7.05	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pKi	5.75	7.02	7.96	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKi	5.70	6.05	6.40	Guide to Pharmacology
CB₂	CNR2	Rat	Cannabinoid	A	pKi	6.44	6.44	6.44	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKi	6.43	6.68	6.80	ChEMBL
CB₂	CNR2	Mouse	Cannabinoid	A	pKi	5.71	5.71	5.71	ChEMBL

Showing 1 to 7 of 7 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Mouse	Cannabinoid	A	pEC50	6.44	6.44	6.44	ChEMBL
CB₁	CNR1	Mouse	Cannabinoid	A	pIC50	4.92	6.17	7.41	ChEMBL
GPR18	GPR18	Human	GPR18, GPR55 and GPR119	A	pEC50	5.42	5.42	5.42	Guide to Pharmacology
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pEC50	7.74	7.74	7.74	Guide to Pharmacology

Showing 1 to 4 of 4 entries

anandamide

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.