GPCRdb

2-arachidonoylglycerol

Agent/drug
Bioactivity

2-arachidonoylglycerol

SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO
InChIKey	RCRCTBLIHCHWDZ-DOFZRALJSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	17
Molecular weight (Da)	378.3

Database connections

Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Rat	Cannabinoid	A	pKi	6.30	6.75	7.20	Guide to Pharmacology
CB₁	CNR1	Human	Cannabinoid	A	pKi	6.00	6.25	6.33	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKi	5.80	6.30	6.80	Guide to Pharmacology
CB₂	CNR2	Human	Cannabinoid	A	pKi	5.85	5.86	5.89	ChEMBL
CB₂	CNR2	Rat	Cannabinoid	A	pKi	7.00	7.00	7.00	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pEC50	7.64	7.64	7.64	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pEC50	7.77	7.77	7.77	ChEMBL
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pEC50	8.52	8.52	8.52	Guide to Pharmacology

Showing 1 to 3 of 3 entries

2-arachidonoylglycerol

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.