CHEMBL1091631


SMILES CC(C)N1C[C@@H](C(=O)N2C[C@H](C)[C@@](O)(c3ccccc3)[C@H](C)C2)[C@H](c2ccc(F)cc2F)C1
InChIKey HSGLTPLGLIYMNU-OLJFDCSVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 456.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pKi 6.94 6.94 6.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 6.12 6.12 6.12 ChEMBL
MC5 MC5R Human Melanocortin A pEC50 5.44 5.44 5.44 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 4.94 4.94 4.94 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 7.16 7.16 7.16 ChEMBL