GPCRdb

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Ligand source activities (1 row/activity)

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

(±)-adrenaline	3139	3H-DHA	60	Human	Binding	pKi	=	10000.00	5.00	-1995	14	-	PDSP KiDatabase	183.1	3	4	4	0.35	CNCC(O)c1ccc(O)c(O)c1	-
(+)-adrenaline	290	None	26	Dog	Binding	Ki	=	3700.00	5.43	-3	5	Binding of [3H]dihydroalprenolol to beta-2 adrenergic receptor of rat cerebral cortical membranes	ChEMBL	183.1	3	4	4	0.35	CNC[C@@H](O)c1ccc(O)c(O)c1	https://dx.doi.org/10.1021/jm990599h
(+)-sulpiride	3703	3H-DHA	66	Rat	Binding	pKi	=	10000.00	5.00	-549	23	-	PDSP KiDatabase	341.1	6	2	5	0.56	CCN1CCC[C@@H]1CNC(=O)c1cc(S(N)(=O)=O)ccc1OC	-
(-)-adrenaline	291	None	40	Human	Binding	pKi	=	-	6.10	-89	35	Unclassified	Guide to Pharmacology	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	https://pubmed.ncbi.nlm.nih.gov/2849109
(-)-adrenaline	291	None	40	Human	Binding	pKi	=	-	6.10	-89	35	Unclassified	Guide to Pharmacology	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	https://pubmed.ncbi.nlm.nih.gov/9295336
(-)-adrenaline	291	None	40	Human	Binding	pKi	=	-	6.10	-89	35	Unclassified	Guide to Pharmacology	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	https://pubmed.ncbi.nlm.nih.gov/14730417
(-)-adrenaline	291	None	40	Human	Binding	pKi	=	-	6.10	-89	35	Unclassified	Guide to Pharmacology	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	https://pubmed.ncbi.nlm.nih.gov/20590599
(-)-adrenaline	291	None	40	Human	Binding	Kd	=	630.00	6.20	-89	35	Binding affinity to human adrenergic beta2 receptor	ChEMBL	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	https://dx.doi.org/10.1016/j.ejmech.2008.12.016
(-)-adrenaline	291	3H-DHA	40	Human	Binding	pKi	=	1100.00	5.96	-89	35	-	PDSP KiDatabase	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	-
(-)-adrenaline	291	125I-CYP	40	Human	Binding	pKi	=	735.00	6.13	-89	35	-	PDSP KiDatabase	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	-
(-)-adrenaline	291	None	40	Human	Binding	pKd	=	6.20	8.21	-89	35	Binding affinity to human adrenergic beta2 receptor	Drug Central	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	-
(-)-adrenaline	291	None	40	Human	Binding	IC50	=	284.00	6.55	-89	35	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	ChEMBL	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	-
(-)-adrenaline	291	None	40	Human	Binding	Ki	=	196.00	6.71	-89	35	DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177)	ChEMBL	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	-
(-)-adrenaline	291	None	40	Human	Binding	Kd	=	630.96	6.20	-89	35	Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nM	ChEMBL	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	https://dx.doi.org/10.1016/j.bmcl.2013.07.052
(-)-adrenaline	291	None	40	Human	Binding	Ki	=	360.00	6.44	-89	35	Displacement of [3H]CGP12177 from human beta2 receptor expressed in CHO cells	ChEMBL	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	https://dx.doi.org/10.1016/j.bmc.2016.04.028
(-)-adrenaline	291	125I-ICYP	40	Human	Binding	pKi	=	3467.36	5.46	-89	35	-	PDSP KiDatabase	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	-
(-)-adrenaline	291	3H-CGP-12177	40	Human	Binding	pKi	=	1995.26	5.70	-89	35	-	PDSP KiDatabase	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	-
(-)-adrenaline	291	None	40	Rat	Binding	Ki	=	720.00	6.14	-12	35	Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranes	ChEMBL	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	https://dx.doi.org/10.1021/jm00076a024
(-)-adrenaline	291	None	40	Rat	Binding	pKi	=	6.14	8.21	-12	35	Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranes	Drug Central	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	-
(-)-adrenaline	291	None	40	Dog	Binding	Ki	=	660.00	6.18	-30	35	Binding of [3H]dihydroalprenolol to beta-2 adrenergic receptor of rat cerebral cortical membranes	ChEMBL	183.1	3	4	4	0.35	CNC[C@H](O)c1ccc(O)c(O)c1	https://dx.doi.org/10.1021/jm990599h

Showing 1 to 20 of 2,550 entries

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

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Ligand source activities (1 row/activity)