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Ligand source activities (1 row/activity)

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

[D-Lys¹,des-Arg¹⁰]kallidin	3627	None	0	Human	Binding	pKi	None	-	7.50	-	1	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9111052
[des-Arg¹⁰]icatibant	1377	None	0	Human	Binding	pKi	None	-	7.50	-1	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10422787
[des-Arg¹⁰]icatibant	1377	None	0	Human	Binding	pKi	None	-	7.50	-1	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9313952
[des-Arg¹⁰]icatibant	1377	None	0	Mouse	Binding	pKi	None	-	7.60	1	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/8856107
[des-Arg¹⁰]icatibant	1377	None	0	Rat	Binding	pKi	None	-	7.50	-1	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10422787
[des-Arg¹⁰]kallidin	1378	None	24	Human	Binding	pKi	=	-	9.80	6	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9111052
[des-Arg¹⁰]kallidin	1378	None	24	Human	Binding	pKi	=	-	9.80	6	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10422787
[des-Arg¹⁰]kallidin	1378	None	24	Human	Binding	pKi	=	-	9.80	6	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9313952
[des-Arg¹⁰]kallidin	1378	None	24	Human	Binding	pKi	=	-	9.80	6	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/8735629
[des-Arg¹⁰]kallidin	1378	None	24	Human	Binding	pKd	None	-	9.40	6	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	-
[des-Arg¹⁰]kallidin	1378	None	24	Human	Binding	IC50	=	0.87	9.06	6	4	Displacement of [3H](Des-Arg10)-Kallidin from bradykinin B1 receptor in human IMR90 cells after 60 mins	ChEMBL	-	-	-	-	-	-	https://dx.doi.org/10.1016/j.bmcl.2013.01.025
[des-Arg¹⁰]kallidin	1378	None	24	Human	Binding	Ki	=	0.22	9.66	6	4	Displacement of [3H](Des-Arg10)-Kallidin from bradykinin B1 receptor in human IMR90 cells after 60 mins	ChEMBL	-	-	-	-	-	-	https://dx.doi.org/10.1016/j.bmcl.2013.01.025
[des-Arg¹⁰]kallidin	1378	None	24	Mouse	Binding	pKi	=	-	8.80	-6	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/8856107
[des-Arg¹⁰]kallidin	1378	None	24	Rat	Binding	pKi	=	-	8.80	-6	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10422787
[des-Arg¹¹]T-kinin	1379	None	0	Human	Binding	pKi	None	-	5.80	-35	2	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10422787
[des-Arg¹¹]T-kinin	1379	None	0	Rat	Binding	pKi	None	-	7.35	35	2	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10422787
[des-Arg⁹]bradykinin	1380	None	0	Human	Binding	pKi	None	-	5.75	-2818	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10422787
[des-Arg⁹]bradykinin	1380	None	0	Human	Binding	pKi	None	-	5.75	-2818	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9313952
[des-Arg⁹]bradykinin	1380	None	0	Mouse	Binding	pKi	None	-	9.20	2818	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/8856107
[des-Phe⁹,des-Arg¹⁰]kallidin	1392	None	0	Human	Binding	pKi	None	-	6.15	-	1	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9111052

Showing 1 to 20 of 761 entries

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

[des-Arg¹⁰]icatibant	1377	None	0	Mouse	Functional	pA2	=	-	7.20	-	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9650825
[des-Arg¹⁰]kallidin	1378	None	24	Rat	Functional	EC50	=	85.00	7.07	-97	4	Compound was evaluated for agonist activity against B1 receptor in rat ileum longitudinal smooth muscle	ChEMBL	-	-	-	-	-	-	https://dx.doi.org/10.1016/S0960-894X(97)10042-7
[Leu⁸,des-Arg⁹]bradykinin	2306	None	11	Mouse	Functional	pA2	=	-	6.90	-	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/8834490
[Leu⁸,des-Arg⁹]bradykinin	2306	None	11	Mouse	Functional	pEC50	None	-	7.30	-	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9276157
[Leu⁹,des-Arg¹⁰]kallidin	2308	None	19	Human	Functional	IC50	=	990.00	6.00	2	2	Antagonist activity against bradykinin B1 receptor in human HeLa cells assessed as inhibition of Des-Arg9-BK-induced increase in intracellular Ca2+ level by Fluro-4 direct calcium dye based fluorescence assay	ChEMBL	-	-	-	-	-	-	https://dx.doi.org/10.1021/acs.jmedchem.6b01011
[Leu⁹,des-Arg¹⁰]kallidin	2308	None	19	Human	Functional	pIC50	=	-	8.90	2	2	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/8063797
[Leu⁹,des-Arg¹⁰]kallidin	2308	None	19	Mouse	Functional	pA2	=	-	7.00	-2	2	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/8834490
B-9430	565	None	0	Human	Functional	pA2	=	-	7.70	-5	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9650825
B-9430	565	None	0	Mouse	Functional	pA2	=	-	6.10	-199	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9650825
B-9858	566	None	0	Human	Functional	pA2	=	-	9.20	-	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9650825
CHEMBL1210741	15225	None	0	Human	Functional	IC50	=	316.00	6.50	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	627.3	10	2	4	6.90	CC(CN1CCCCC1)c1ccc2c(c1)CCC[C@H]2NC(=O)C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1	https://dx.doi.org/10.1016/j.bmcl.2010.06.010
CHEMBL1210742	15226	None	0	Human	Functional	IC50	=	88.00	7.06	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	639.3	10	2	4	6.83	O=C(C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1)N[C@@H]1CCCc2cc(C3(CN4CCCCC4)CC3)ccc21	https://dx.doi.org/10.1016/j.bmcl.2010.06.010
CHEMBL1210743	15227	None	0	Human	Functional	IC50	=	41.00	7.39	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	625.3	10	2	4	6.81	C=C(CN1CCCCC1)c1ccc2c(c1)CCC[C@H]2NC(=O)C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1	https://dx.doi.org/10.1016/j.bmcl.2010.06.010
CHEMBL1210744	15228	None	0	Human	Functional	IC50	=	9.70	8.01	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	611.2	10	2	4	6.42	C=C(CN1CCCC1)c1ccc2c(c1)CCC[C@H]2NC(=O)C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1	https://dx.doi.org/10.1016/j.bmcl.2010.06.010
CHEMBL1210745	15229	None	0	Human	Functional	IC50	=	3.90	8.41	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	627.2	10	3	5	5.39	C=C(CN1CC[C@H](O)C1)c1ccc2c(c1)CCC[C@H]2NC(=O)C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1	https://dx.doi.org/10.1016/j.bmcl.2010.06.010
CHEMBL1210746	15230	None	0	Human	Functional	IC50	=	15.00	7.82	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	627.2	10	3	5	5.39	C=C(CN1CC[C@@H](O)C1)c1ccc2c(c1)CCC[C@H]2NC(=O)C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1	https://dx.doi.org/10.1016/j.bmcl.2010.06.010
CHEMBL1210747	15231	None	0	Human	Functional	IC50	=	206.00	6.69	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	597.2	10	2	4	6.03	C=C(CN1CCC1)c1ccc2c(c1)CCC[C@H]2NC(=O)C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1	https://dx.doi.org/10.1016/j.bmcl.2010.06.010
CHEMBL1210748	15232	None	0	Human	Functional	IC50	=	154.00	6.81	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	585.2	10	2	4	5.88	C=C(CN(C)C)c1ccc2c(c1)CCC[C@H]2NC(=O)C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1	https://dx.doi.org/10.1016/j.bmcl.2010.06.010
CHEMBL1210749	15233	None	0	Human	Functional	IC50	=	32.00	7.50	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	601.2	12	4	5	4.90	C=C(CNCCO)c1ccc2c(c1)CCC[C@H]2NC(=O)C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1	https://dx.doi.org/10.1016/j.bmcl.2010.06.010
CHEMBL1210750	15234	None	0	Human	Functional	IC50	=	23.00	7.64	-	1	Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium flux	ChEMBL	615.2	13	3	5	5.56	C=C(CNCCOC)c1ccc2c(c1)CCC[C@H]2NC(=O)C[C@@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1	https://dx.doi.org/10.1016/j.bmcl.2010.06.010

Showing 1 to 20 of 625 entries

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Ligand source activities (1 row/activity)