GPCRdb

Ligand source activities (1 row/activity)

Affinity
Potency

Search:

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

CHEMBL1802413	211412	None	2	Human	Binding	IC50	=	1.26	8.90	-	1	Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based method	ChEMBL	-	-	-	-	-	CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm300507d
CHEMBL1802414	211413	None	11	Human	Binding	Ki	=	2.04	8.69	-	1	Displacement of [125I]-43RFa from human QRFP receptor expressed in CHO cells by TopCount scintillation counting method	ChEMBL	-	-	-	-	-	CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/acs.jmedchem.1c00256
CHEMBL1802425	211424	None	0	Human	Binding	IC50	=	8730.00	5.06	-	1	Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based method	ChEMBL	-	-	-	-	-	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm300507d
CHEMBL2170390	82208	None	0	Human	Binding	IC50	=	2987.00	5.53	-	1	Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based method	ChEMBL	830.4	25	13	11	-3.54	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm300507d
CHEMBL2170403	82218	None	0	Human	Binding	IC50	=	1994.00	5.70	-	1	Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based method	ChEMBL	886.5	26	12	12	-3.01	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN(CC(O)CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN1CCNCC1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm300507d
CHEMBL3287584	111870	None	0	Human	Binding	IC50	=	158.49	6.80	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	346.1	6	2	4	5.37	COc1ccc(NC(=N)c2cccs2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287585	111871	None	0	Human	Binding	IC50	=	79.43	7.10	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	424.1	6	1	5	3.58	COc1ccc(Cl)cc1NS(=O)(=O)c1ccc(OC)c2c1CC[C@@H](N(C)C)C2	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287586	111872	None	0	Human	Binding	IC50	=	125.89	6.90	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	346.1	6	2	4	5.37	COc1ccc(NC(=N)c2ccsc2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287810	111964	None	1	Human	Binding	IC50	=	25.12	7.60	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	340.2	6	2	3	5.31	COc1ccc(NC(=N)c2ccccc2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287811	111965	None	0	Human	Binding	IC50	=	100.00	7.00	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	360.1	6	2	4	5.68	COc1ccc(NC(=N)c2cc(C)cs2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287813	111967	None	0	Human	Binding	IC50	=	125.89	6.90	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	424.0	6	2	4	6.13	COc1ccc(NC(=N)c2ccc(Br)s2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287814	111968	None	1	Human	Binding	IC50	=	39.81	7.40	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	374.1	6	2	3	5.96	COc1ccc(NC(=N)c2ccc(Cl)cc2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287817	111970	None	0	Human	Binding	IC50	=	25118.86	4.60	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	347.1	6	2	5	4.76	COc1ccc(NC(=N)c2nccs2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287819	111972	None	0	Human	Binding	IC50	=	501.19	6.30	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	341.2	6	2	4	4.70	COc1ccc(NC(=N)c2cccnc2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287821	111974	None	0	Human	Binding	IC50	=	630.96	6.20	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	360.1	6	1	4	5.42	C/N=C(/Nc1ccc(OC)c(CSC2CCCC2)c1)c1cccs1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287824	111976	None	0	Human	Binding	IC50	=	3981.07	5.40	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	340.2	6	2	3	5.31	COc1ccc(C(=N)Nc2ccccc2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287825	111977	None	0	Human	Binding	IC50	=	2511.89	5.60	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	316.1	5	2	3	5.36	N=C(Nc1cccc(CSC2CCCC2)c1)c1cccs1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287826	111978	None	0	Human	Binding	IC50	=	10000.00	5.00	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	330.1	5	2	3	5.67	Cc1ccc(NC(=N)c2cccs2)cc1CSC1CCCC1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287827	111979	None	0	Human	Binding	IC50	=	1258.93	5.90	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	334.1	5	2	3	5.50	N=C(Nc1ccc(F)c(CSC2CCCC2)c1)c1cccs1	https://dx.doi.org/10.1021/ml400519h
CHEMBL3287828	111980	None	0	Human	Binding	IC50	=	3981.07	5.40	-	1	Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting	ChEMBL	350.1	5	2	3	6.01	N=C(Nc1ccc(Cl)c(CSC2CCCC2)c1)c1cccs1	https://dx.doi.org/10.1021/ml400519h

Showing 1 to 20 of 42 entries

Search:

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

CHEMBL1800099	211399	None	0	Human	Functional	EC50	=	43.20	7.37	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	-	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802364	211400	None	0	Human	Functional	EC50	=	1471.00	5.83	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802365	211401	None	0	Human	Functional	EC50	=	741.00	6.13	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802366	211402	None	0	Human	Functional	EC50	=	817.00	6.09	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802367	211403	None	0	Human	Functional	EC50	=	1820.00	5.74	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	CC(C)(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802368	211404	None	0	Human	Functional	EC50	=	1631.00	5.79	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802369	211405	None	0	Human	Functional	EC50	=	233.00	6.63	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	CCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802370	211406	None	0	Human	Functional	EC50	=	355.00	6.45	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802371	211407	None	0	Human	Functional	EC50	=	1103.00	5.96	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802372	211408	None	0	Human	Functional	EC50	=	374.00	6.43	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802373	63840	None	0	Human	Functional	EC50	=	166.00	6.78	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	3010.5	98	42	40	-11.22	CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N(Cc1ccccc1)Cc1ccccc1	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802374	63841	None	0	Human	Functional	EC50	=	2545.00	5.59	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	899.5	25	12	10	-1.84	CC(C)(C)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802375	63842	None	0	Human	Functional	EC50	=	722.00	6.14	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	919.4	26	12	10	-1.57	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802376	211409	None	0	Human	Functional	EC50	=	826.00	6.08	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802377	63843	None	0	Human	Functional	EC50	=	588.00	6.23	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	977.5	26	12	10	-0.67	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802378	63844	None	0	Human	Functional	EC50	=	695.00	6.16	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	909.4	26	12	11	-1.98	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)c1ccco1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802379	211410	None	0	Human	Functional	EC50	=	455.00	6.34	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	CN(C)C(=NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)N(C)C	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802380	63845	None	0	Human	Functional	EC50	=	830.00	6.08	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	951.4	27	12	10	-1.51	N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)Cc1ccc(F)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802412	211411	None	0	Human	Functional	EC50	=	1308.00	5.88	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c
CHEMBL1802413	211412	None	2	Human	Functional	EC50	=	10.40	7.98	-	1	Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis	ChEMBL	-	-	-	-	-	CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O	https://dx.doi.org/10.1021/jm200418c

Showing 1 to 20 of 112 entries

Join us

Cite us

Main reference

Ligand source activities (1 row/activity)