GPCRdb

Ligand source activities (1 row/activity)

Potency
Affinity

Get vendors

Ligands					Receptor			Assay information							Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity (Potency)	# tested GPCRs (Potency)	Species	p-value (-log)	Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	42637503	202596	0	None	100	3	Human	9.4	pEC50	=	9.4	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL558161	202596	0	None	100	3	Human	9.4	pEC50	=	9.4	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL563125	222525	0	None	-	1	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](c2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm801314f
	42637069	202288	0	None	48	3	Human	8.4	pEC50	=	8.4	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL553655	202288	0	None	48	3	Human	8.4	pEC50	=	8.4	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL556949	222515	0	None	-	1	Human	7.5	pEC50	=	7.5	Functional	Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14Agonist activity at human sst1 receptor expressed in Chinese hamster CCL39 cells by luciferase reporter gene assay relative to somatostatin-14	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	68254010	173193	0	None	-1778	3	Human	5.2	pIC50	=	5.2	Functional	Antagonist activity at human SSTR1 expressed in CHO-K1 cell membranesAntagonist activity at human SSTR1 expressed in CHO-K1 cell membranes	ChEMBL	559	10	2	7	6.6	CCOc1cc(CN2CC[C@H]3C(Nc4nc5ccc(C(=O)O)cc5o4)CC[C@H]32)cc(OCC)c1-c1ccc(F)cc1	10.1021/acsmedchemlett.8b00305
	CHEMBL4277106	173193	0	None	-1778	3	Human	5.2	pIC50	=	5.2	Functional	Antagonist activity at human SSTR1 expressed in CHO-K1 cell membranesAntagonist activity at human SSTR1 expressed in CHO-K1 cell membranes	ChEMBL	559	10	2	7	6.6	CCOc1cc(CN2CC[C@H]3C(Nc4nc5ccc(C(=O)O)cc5o4)CC[C@H]32)cc(OCC)c1-c1ccc(F)cc1	10.1021/acsmedchemlett.8b00305
	145705877	224515	0	None	1	5	Human	8.1	pIC50	=	8.1	Functional	NoneNone	Drug Central	1047	17	9	11	3.4	NCCCC[C@@H]1NC(=O)[C@@H](CC2=CNC3=C2C=CC=C3)NC(=O)C(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=C(OCC3=CC=CC=C3)C=C2)NC1=O)OC(=O)NCCN)C1=CC=CC=C1	None
	2027	7442	0	None	-398	5	Human	5.6	pIC50	=	5.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11897676
	2003	7428	0	None	-79	2	Human	6.4	pIC50	=	6.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8100350
	2006	7693	0	None	-15	2	Rat	7.3	pIC50	=	7.3	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9166718
	2010	8158	0	None	-	1	Human	7.5	pIC50	=	7.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658864
	2011	8156	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658865
	2018	9781	28	None	-63	5	Human	8.0	pIC50	=	8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15477717
	9941444	9781	28	None	-63	5	Human	8.0	pIC50	=	8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15477717
	CHEMBL3349607	9781	28	None	-63	5	Human	8.0	pIC50	=	8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15477717
	DB06663	9781	28	None	-63	5	Human	8.0	pIC50	=	8	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15477717
	2025	8064	0	None	-	1	Human	8.2	pIC50	=	8.2	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658865
	2009	8155	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658865
	2013	8961	0	None	-3	6	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	12450568
	2012	8157	0	None	1	4	Human	9.0	pIC50	=	9	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15658864
	2026	7441	0	None	-31	5	Human	6.0	pIC50	None	6	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11897676
	2019	10447	0	None	-50	4	Rat	8.4	pIC50	None	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9166718
	44386062	10447	0	None	-50	4	Rat	8.4	pIC50	None	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9166718
	CHEMBL440072	10447	0	None	-50	4	Rat	8.4	pIC50	None	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9166718
	2006	7693	0	None	15	2	Human	8.5	pIC50	None	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011

Get vendors

Ligands					Receptor			Assay information							Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity (Affinity)	# tested GPCRs (Affinity)	Species	p-value (-log)	Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	124168080	188613	0	None	-	0	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human SST1Agonist activity at human SST1	ChEMBL	507	6	2	7	4.4	Cc1cc(Cl)cc(-c2cnc3ncn(-c4cc(O)cc(F)c4)c(=O)c3c2CN(C)C[C@@H]2CCCN2)c1	10.1016/j.bmcl.2020.127496
	CHEMBL4778342	188613	0	None	-	0	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human SST1Agonist activity at human SST1	ChEMBL	507	6	2	7	4.4	Cc1cc(Cl)cc(-c2cnc3ncn(-c4cc(O)cc(F)c4)c(=O)c3c2CN(C)C[C@@H]2CCCN2)c1	10.1016/j.bmcl.2020.127496
	16129706	215810	40	None	-6	5	Human	9.9	pIC50	=	9.9	Binding	Binding affinity to Somatostatin receptor type 1 (unknown origin) by radioligand displacement assayBinding affinity to Somatostatin receptor type 1 (unknown origin) by radioligand displacement assay	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmc.2013.03.016
	CHEMBL1823872	215810	40	None	-6	5	Human	9.9	pIC50	=	9.9	Binding	Binding affinity to Somatostatin receptor type 1 (unknown origin) by radioligand displacement assayBinding affinity to Somatostatin receptor type 1 (unknown origin) by radioligand displacement assay	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmc.2013.03.016
	42637503	202596	0	None	-	0	Human	9.7	pIC50	=	9.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL558161	202596	0	None	-	0	Human	9.7	pIC50	=	9.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	45268875	202389	0	None	-	0	Human	9.1	pIC50	=	9.1	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1363	19	12	15	2.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)CSSC[C@@H](C(=O)N[C@@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL555977	202389	0	None	-	0	Human	9.1	pIC50	=	9.1	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1363	19	12	15	2.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)CSSC[C@@H](C(=O)N[C@@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL408338	219485	0	None	-	0	Human	9.0	pIC50	=	9.0	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm049520l
	45268875	202389	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Binding affinity to sst1 receptor in human prostate cancer cells by autoradiographyBinding affinity to sst1 receptor in human prostate cancer cells by autoradiography	ChEMBL	1363	19	12	15	2.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)CSSC[C@@H](C(=O)N[C@@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL555977	202389	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Binding affinity to sst1 receptor in human prostate cancer cells by autoradiographyBinding affinity to sst1 receptor in human prostate cancer cells by autoradiography	ChEMBL	1363	19	12	15	2.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)CSSC[C@@H](C(=O)N[C@@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	42637069	202288	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL553655	202288	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL409100	219525	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@H](C(=O)O)NC(=O)[C@@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm010037+
	70689723	80743	0	None	-	0	Human	8.9	pIC50	=	8.9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1170	16	9	12	4.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL2021559	80743	0	None	-	0	Human	8.9	pIC50	=	8.9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1170	16	9	12	4.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	16129706	215810	40	None	-6	5	Human	8.8	pIC50	=	8.8	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL1823872	215810	40	None	-6	5	Human	8.8	pIC50	=	8.8	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	16129706	215810	40	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL1823872	215810	40	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL442494	220692	0	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm801205x
	16129706	215810	40	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm049519m
	CHEMBL1823872	215810	40	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm049519m
	CHEMBL262379	217317	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm049520l
	CHEMBL425465	220114	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL3350911	218308	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	118718507	122136	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL	1050	14	11	12	3.4	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)NC(C)(C)C)NC1=O	10.1021/jm970730q
	CHEMBL3349670	122136	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL	1050	14	11	12	3.4	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)NC(C)(C)C)NC1=O	10.1021/jm970730q
	CHEMBL2079558	215973	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349505	218189	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(N)=O)[C@@H](C)O	10.1021/jm970730q
	CHEMBL3349506	218190	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(N)=O)[C@@H](C)O	10.1021/jm970730q
	CHEMBL3349508	218192	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(N)=O)[C@@H](C)O	10.1021/jm970730q
	CHEMBL3349597	218205	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O	10.1021/jm970730q
	CHEMBL3349608	218215	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm970730q
	CHEMBL3349610	218216	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(C)(C)SSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL3349611	218217	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm970730q
	CHEMBL3349612	218218	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccccc2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL3349613	218219	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccccc2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL3349617	218222	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm970730q
	CHEMBL3349618	218223	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm970730q
	CHEMBL3349663	218226	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3)c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349665	218228	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3)c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349668	218231	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3)c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349673	218235	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349674	218236	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O	10.1021/jm970730q
	CHEMBL3349675	218237	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970730q
	CHEMBL3349678	218240	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL3349680	218242	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O	10.1021/jm970730q
	49865345	22683	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1043	18	13	12	0.7	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C/C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL1223230	22683	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1043	18	13	12	0.7	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C/C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL3349667	218230	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL412629	219791	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CNCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3349679	218241	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm970730q
	CHEMBL408825	219513	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL2374244	217162	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]3CCC(=O)NCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3349507	218191	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	162646037	186293	0	None	-	0	Human	5.0	pIC50	=	5.0	Binding	Displacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assayDisplacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assay	ChEMBL	1387	27	17	19	-2.0	CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O	10.1021/acs.jmedchem.6b00164
	CHEMBL4741230	186293	0	None	-	0	Human	5.0	pIC50	=	5.0	Binding	Displacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assayDisplacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assay	ChEMBL	1387	27	17	19	-2.0	CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O	10.1021/acs.jmedchem.6b00164
	25188780	19203	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	489	10	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1185941	19203	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	489	10	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL442605	19203	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	489	10	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL540408	222493	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL3349666	218229	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3)c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL410047	219576	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL408611	219502	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CN[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CNC(C)C)cc2)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm049520l
	CHEMBL3350881	218283	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL3350895	218296	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL426698	220127	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)CNCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	122179477	128252	5	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Inhibition of SSTR1 receptor (unknown origin)Inhibition of SSTR1 receptor (unknown origin)	ChEMBL	525	5	3	9	3.2	CCn1cc([C@@]2(c3nn(C)c(=O)o3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1	10.1021/ml500514w
	CHEMBL3582336	128252	5	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Inhibition of SSTR1 receptor (unknown origin)Inhibition of SSTR1 receptor (unknown origin)	ChEMBL	525	5	3	9	3.2	CCn1cc([C@@]2(c3nn(C)c(=O)o3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1	10.1021/ml500514w
	CHEMBL1824049	215812	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL3122130	217887	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@H](NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL500326	220890	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL554624	222505	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccccc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL556949	222515	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL387005	219182	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]3CCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	CHEMBL411002	219635	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049519m
	CHEMBL265120	217416	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CN[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CNC(C)C)cc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm049520l
	CHEMBL411002	219635	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL1824050	215813	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL3349671	218233	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc(-c3ccccc3)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL410144	219580	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL385811	219147	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL436887	220470	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL414749	219932	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL438776	220577	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL555737	222510	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL414716	219928	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL2079563	215975	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL446380	220724	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	44388108	168474	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1667	22	20	21	0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL413413	168474	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1667	22	20	21	0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL414692	219926	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL3351090	218323	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	44388133	173982	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1710	22	21	22	-0.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC(=O)NCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL429164	173982	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1710	22	21	22	-0.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC(=O)NCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL563461	222527	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@](C)([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL268205	217522	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL436887	220470	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL440083	220640	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCNC(N)=O)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3122129	217886	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)COCCOCCNC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL437905	220517	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)N(C)C(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL3122124	217882	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		CCCC[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@@H](CO)C(=O)NCC(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL409952	219566	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL2373256	217152	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	25188220	19263	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL1186489	19263	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL466609	19263	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL407858	219469	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	42637283	202293	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1334	20	11	14	5.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL553672	202293	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1334	20	11	14	5.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL559150	222523	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL265836	217445	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049519m
	CHEMBL386784	219171	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL442494	220692	0	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Binding affinity to human sst1 by in vitro receptor autoradiography assayBinding affinity to human sst1 by in vitro receptor autoradiography assay	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/ml200032v
	CHEMBL442494	220692	0	None	-6	5	Human	8.7	pIC50	=	8.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst1 receptor expressed in CHOK1 cells by autoradiographyDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst1 receptor expressed in CHOK1 cells by autoradiography	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm701445q
	CHEMBL1823873	215811	9	None	1	4	Human	8.6	pIC50	=	8.6	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL442494	220692	0	None	-6	5	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptorDisplacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptor	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm070886i
	CHEMBL442494	220692	0	None	-6	5	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm1005868
	CHEMBL1909004	215853	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL559022	215853	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL413419	219844	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL263340	217347	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL1824051	215814	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	CHEMBL442494	220692	0	None	-6	5	Human	8.6	pIC50	=	8.6	Binding	Displacement of [125I][LTT]SRIF28 from human cloned sst1 receptor by autoradiographyDisplacement of [125I][LTT]SRIF28 from human cloned sst1 receptor by autoradiography	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm701618q
	CHEMBL442494	220692	0	None	-6	5	Human	8.5	pIC50	=	8.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm801314f
	45273131	201565	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1271	20	11	14	2.8	CN(C(=O)c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(C(N)=O)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm801314f
	CHEMBL538451	201565	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1271	20	11	14	2.8	CN(C(=O)c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(C(N)=O)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm801314f
	CHEMBL2311181	216286	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	156009460	185004	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1667	22	20	21	0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL4649897	185004	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1667	22	20	21	0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL439135	220605	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3350897	218298	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](c1c[nH]c2ccccc12)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030245x
	CHEMBL3350899	218300	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL3349614	218220	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL504248	220954	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@H]1CCSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL504457	220956	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL440066	220637	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL413442	219851	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)N(C)C(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	122179457	128232	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Binding affinity to somatostatin receptor type 1 (unknown origin)Binding affinity to somatostatin receptor type 1 (unknown origin)	ChEMBL	495	4	3	8	3.7	Cc1nc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)no1	10.1016/j.bmcl.2016.02.022
	CHEMBL3582317	128232	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Binding affinity to somatostatin receptor type 1 (unknown origin)Binding affinity to somatostatin receptor type 1 (unknown origin)	ChEMBL	495	4	3	8	3.7	Cc1nc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)no1	10.1016/j.bmcl.2016.02.022
	16737814	92282	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL227212	92282	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL504838	92282	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	16737814	92282	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL227212	92282	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL504838	92282	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	551	11	4	4	3.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm070246f
	10114	9334	23	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 minsDisplacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 mins	ChEMBL	494	4	3	7	4.3	Fc1ccc(cc1)c1cnc([nH]1)[C@H]1Cc2c3ccccc3[nH]c2[C@@](N1)(c1noc(n1)C)c1cnn(c1)C	10.1021/ml300063m
	56927659	9334	23	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 minsDisplacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 mins	ChEMBL	494	4	3	7	4.3	Fc1ccc(cc1)c1cnc([nH]1)[C@H]1Cc2c3ccccc3[nH]c2[C@@](N1)(c1noc(n1)C)c1cnn(c1)C	10.1021/ml300063m
	CHEMBL2204935	9334	23	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 minsDisplacement of [125I]SS-28 from human SSTR-1 transfected in CHO cells after 60 to 90 mins	ChEMBL	494	4	3	7	4.3	Fc1ccc(cc1)c1cnc([nH]1)[C@H]1Cc2c3ccccc3[nH]c2[C@@](N1)(c1noc(n1)C)c1cnn(c1)C	10.1021/ml300063m
	CHEMBL405784	219358	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL407027	219412	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3349669	218232	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL265615	217436	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	25187683	19223	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	627	12	4	4	5.2	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1186082	19223	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	627	12	4	4	5.2	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL448713	19223	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	627	12	4	4	5.2	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL410428	219599	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	49865343	22681	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1147	20	12	13	2.2	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL1223228	22681	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1147	20	12	13	2.2	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL384195	219098	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(=O)N2C)cc1	10.1021/jm049520l
	25187396	19456	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	475	9	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1187397	19456	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	475	9	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL501699	19456	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	475	9	4	4	2.4	CC(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)NCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL5282589	200943	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of human somatostatin receptor type 1Inhibition of human somatostatin receptor type 1	ChEMBL	633	14	7	7	0.1	CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1Cc2c([nH]c3ccccc23)CN([C@@H](CCCCN)C(=O)N[C@H](C(N)=O)[C@@H](C)O)C1=O	10.1021/acs.jmedchem.6b01029
	CHEMBL262551	217320	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	44388036	167031	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1645	18	19	20	-0.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@@H](NC(=O)[C@H](Cc4ccc(O)cc4I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL411001	167031	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1645	18	19	20	-0.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@@H](NC(=O)[C@H](Cc4ccc(O)cc4I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL438576	220558	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	59568713	138906	15	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibition of somatostatin receptor subtype 1 (unknown origin)Inhibition of somatostatin receptor subtype 1 (unknown origin)	ChEMBL	466	6	2	8	2.0	Cc1c([C@@H](O)CN2CCN(C[C@H](O)c3ccc4c(c3C)COC4=O)CC2)ccc2c1COC2=O	10.1021/acsmedchemlett.6b00122
	CHEMBL3696475	138906	15	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibition of somatostatin receptor subtype 1 (unknown origin)Inhibition of somatostatin receptor subtype 1 (unknown origin)	ChEMBL	466	6	2	8	2.0	Cc1c([C@@H](O)CN2CCN(C[C@H](O)c3ccc4c(c3C)COC4=O)CC2)ccc2c1COC2=O	10.1021/acsmedchemlett.6b00122
	70683416	80742	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1170	16	9	12	4.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL2021544	80742	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1170	16	9	12	4.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL425090	220108	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL452157	220755	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030246p
	CHEMBL3350898	218299	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL452157	220755	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL452157	220755	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm200307v
	25187400	19466	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	537	10	4	4	3.7	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1187495	19466	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	537	10	4	4	3.7	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL504930	19466	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	537	10	4	4	3.7	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL452157	220755	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL452157	220755	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm801314f
	CHEMBL452157	220755	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL265912	217450	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm010037+
	CHEMBL3350894	218295	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	44388134	148193	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1710	22	21	22	-0.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL384072	148193	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1710	22	21	22	-0.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	46902023	23810	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cellsDisplacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cells	ChEMBL	544	11	3	7	3.7	COC[C@H]1O[C@@H](OCc2ccc3ccccc3c2)[C@H](NC(=O)CCN)[C@@H](OCc2ccc3ccccc3c2)[C@@H]1O	10.1021/jm1002777
	CHEMBL1254476	23810	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Displacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cellsDisplacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cells	ChEMBL	544	11	3	7	3.7	COC[C@H]1O[C@@H](OCc2ccc3ccccc3c2)[C@H](NC(=O)CCN)[C@@H](OCc2ccc3ccccc3c2)[C@@H]1O	10.1021/jm1002777
	CHEMBL1907758	215847	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030245x
	CHEMBL442494	220692	0	None	-6	5	Human	8.5	pIC50	=	8.5	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm701444y
	CHEMBL442494	220692	0	None	-6	5	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm049520l
	16151826	202635	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1555	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL558600	202635	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1555	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	44388121	173501	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1555	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL428295	173501	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1555	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL1908981	215849	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL539710	215849	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL1907758	215847	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 1 expressed in CHO-K1 cells; (n=5)In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 1 expressed in CHO-K1 cells; (n=5)	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm040794i
	CHEMBL386922	219180	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL1907758	215847	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0302445
	CHEMBL1907758	215847	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030243c
	CHEMBL409653	219554	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL414571	219923	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL447989	220732	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1SS[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL265846	217446	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm010037+
	CHEMBL552013	222500	3	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm801314f
	CHEMBL3349664	218227	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL2371059	216785	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		CNc1ccc(C(C(C)C)[C@@H]2NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC2=O)cc1	10.1021/jm030245x
	CHEMBL407125	219422	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)N(C)C(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL3350905	218303	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	CHEMBL3122123	217881	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		CCCC[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CSSC[C@@H](C(=O)N[C@@H](CO)C(=O)NCC(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL386023	219152	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL413441	219850	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3350884	218286	1	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O	10.1021/jm030245x
	CHEMBL428799	220250	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3350891	218293	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL437451	220499	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm010037+
	CHEMBL404819	219313	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL413378	219842	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccc([N+](=O)[O-])cc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL1908984	215851	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL563124	215851	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL504395	220955	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@H]1CSS[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	42637136	203283	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL563462	203283	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1074	15	10	13	1.6	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	25189054	19476	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	685	11	4	6	3.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	CHEMBL1187568	19476	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	685	11	4	6	3.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	CHEMBL509513	19476	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	685	11	4	6	3.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	25187955	19208	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	646	9	4	4	4.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC3(CCc4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL1185951	19208	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	646	9	4	4	4.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC3(CCc4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL443084	19208	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	646	9	4	4	4.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC3(CCc4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL3122127	217884	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@H](NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)NCC(=O)N[C@H]1CSSC[C@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC1=O	10.1016/j.ejmech.2013.12.003
	25187679	19443	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	571	10	4	4	4.3	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccc(Cl)cc2)C1=O	10.1021/jm801205x
	CHEMBL1187340	19443	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	571	10	4	4	4.3	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccc(Cl)cc2)C1=O	10.1021/jm801205x
	CHEMBL499398	19443	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	571	10	4	4	4.3	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)c2ccc(Cl)cc2)C1=O	10.1021/jm801205x
	25189327	19468	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	601	11	4	4	4.7	NCCCC[C@@H](C(=O)NCc1cccc2ccccc12)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1187509	19468	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	601	11	4	4	4.7	NCCCC[C@@H](C(=O)NCc1cccc2ccccc12)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL505888	19468	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	601	11	4	4	4.7	NCCCC[C@@H](C(=O)NCc1cccc2ccccc12)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	118719101	122218	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1356	21	16	16	2.5	CNc1ccc(C(C(C)C)[C@@H]2NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC2=O)cc1	10.1021/jm030245x
	CHEMBL3350724	122218	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1356	21	16	16	2.5	CNc1ccc(C(C(C)C)[C@@H]2NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC2=O)cc1	10.1021/jm030245x
	CHEMBL1824052	215815	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm200307v
	42637563	202289	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	989	12	9	12	2.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc3ccc(O)cc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL553656	202289	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	989	12	9	12	2.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc3ccc(O)cc3)NC2=O)cc1	10.1021/jm801314f
	44388124	166149	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1680	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL410048	166149	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1680	21	18	21	-0.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	44325273	214087	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)	ChEMBL	554	7	2	4	5.4	NCCCC1CCCN2C(=O)[C@@H](Cc3c[nH]c4ccccc34)SCCN(Cc3cccc4ccccc34)C(=O)C12	10.1016/s0960-894x(00)00552-7
	CHEMBL93351	214087	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)	ChEMBL	554	7	2	4	5.4	NCCCC1CCCN2C(=O)[C@@H](Cc3c[nH]c4ccccc34)SCCN(Cc3cccc4ccccc34)C(=O)C12	10.1016/s0960-894x(00)00552-7
	CHEMBL2111257	215995	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](C)c2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm0302445
	CHEMBL3350357	218254	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030246p
	CHEMBL525030	222410	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@H]1SSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL415144	219951	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3I)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL2369510	216410	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL1909006	215854	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccccc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL538948	215854	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccccc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	44368406	17039	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1022	9	11	12	1.1	C[C@@H]1NC(=O)N(C)[C@H](O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL1161332	17039	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1022	9	11	12	1.1	C[C@@H]1NC(=O)N(C)[C@H](O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL262790	217330	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL3350886	218288	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL269485	217570	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CCN(CC)C(=N)NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC1=O	10.1021/jm010037+
	CHEMBL2079559	215974	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	44388029	103229	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1659	18	18	20	0.0	CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]3CCCCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	CHEMBL262258	103229	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1659	18	18	20	0.0	CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]3CCCCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	10796238	215976	2	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL2079626	215976	2	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	DB06791	215976	2	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm970730q
	CHEMBL3350885	218287	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H]([C@H](C)c2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL2079558	215973	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL2079559	215974	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2cccc(-c3ccccc3)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL407051	219413	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL406816	219402	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL1824055	215818	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030246p
	CHEMBL1824055	215818	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL1824055	215818	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm200307v
	CHEMBL216992	216127	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL2369533	216411	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm010037+
	CHEMBL406197	219377	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	10577746	214031	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)	ChEMBL	514	8	3	4	4.6	NCCCC[C@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)SCCN(Cc2cccc3ccccc23)C1=O	10.1016/s0960-894x(00)00552-7
	CHEMBL92914	214031	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]Tyr11-SRIF)	ChEMBL	514	8	3	4	4.6	NCCCC[C@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)SCCN(Cc2cccc3ccccc23)C1=O	10.1016/s0960-894x(00)00552-7
	CHEMBL3349677	218239	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	11563877	171499	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR1 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting methodDisplacement of [125I]somatostatin-14 (Tyr11) from human SSTR1 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting method	ChEMBL	668	9	3	5	5.7	Cc1cc(F)ccc1N1CCN(C(=O)N[C@@H](C(=O)Nc2cc(CN(C)C)ccc2OC(F)(F)F)[C@@H](C)c2c[nH]c3ccccc23)CC1=O	10.1016/j.bmc.2017.09.031
	CHEMBL4217405	171499	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR1 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting methodDisplacement of [125I]somatostatin-14 (Tyr11) from human SSTR1 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting method	ChEMBL	668	9	3	5	5.7	Cc1cc(F)ccc1N1CCN(C(=O)N[C@@H](C(=O)Nc2cc(CN(C)C)ccc2OC(F)(F)F)[C@@H](C)c2c[nH]c3ccccc23)CC1=O	10.1016/j.bmc.2017.09.031
	CHEMBL3350893	218294	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL413888	219875	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL412473	219773	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CO)N(C)C(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	42637210	202386	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	989	12	9	12	2.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc3ccc(O)cc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL555956	202386	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	989	12	9	12	2.4	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc3ccc(O)cc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL407120	219419	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3349676	218238	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccccc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL406559	219392	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)N(C)C(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	25187398	19220	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	4.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1186066	19220	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	4.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL448026	19220	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	4.0	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CCc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL503036	220939	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1CSS[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL415582	219969	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		C[C@@H](c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0302445
	CHEMBL2371100	216791	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand	ChEMBL		None	None	None		C[C@@H](c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030246p
	11468916	122241	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1137	15	14	14	0.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	CHEMBL3350910	122241	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1137	15	14	14	0.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	CHEMBL441202	220663	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	71461685	86322	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL2114095	86322	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	49865347	22685	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1197	20	12	13	3.4	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccc3ccccc23)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)N1	10.1021/jm1005868
	CHEMBL1223232	22685	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Displacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiographyDisplacement of [125I]-[LTT] SIRF-28 from human SST1 receptor expressed in CHO cells by autoradiography	ChEMBL	1197	20	12	13	3.4	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccc3ccccc23)C(=O)N[C@H](Cc2cc3ccccc3[nH]2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)N1	10.1021/jm1005868
	122179477	128252	5	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Displacement of [125I]SS-14 from human recombinant SSTR1 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assayDisplacement of [125I]SS-14 from human recombinant SSTR1 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assay	ChEMBL	525	5	3	9	3.2	CCn1cc([C@@]2(c3nn(C)c(=O)o3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1	10.1021/ml500514w
	CHEMBL3582336	128252	5	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Displacement of [125I]SS-14 from human recombinant SSTR1 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assayDisplacement of [125I]SS-14 from human recombinant SSTR1 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assay	ChEMBL	525	5	3	9	3.2	CCn1cc([C@@]2(c3nn(C)c(=O)o3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1	10.1021/ml500514w
	CHEMBL415143	219950	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)N(C)C(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL3349672	218234	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)N[C@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm970730q
	CHEMBL263587	217357	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm049519m
	CHEMBL1908982	215850	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL552988	215850	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL411411	219663	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]3CCC(=O)NCC[C@@H](NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL1909003	215852	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CCCCCCC[C@@H]1NC(=O)[C@H](Cc2ccc(O)c(I)c2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CNC(C)C)cc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC1=O	10.1021/jm801314f
	CHEMBL540721	215852	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL		None	None	None		CCCCCCC[C@@H]1NC(=O)[C@H](Cc2ccc(O)c(I)c2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(CNC(C)C)cc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC1=O	10.1021/jm801314f
	44388028	175546	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1645	18	19	20	-0.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@H](NC(=O)[C@H](Cc4ccc(O)cc4I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL437348	175546	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1645	18	19	20	-0.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCCC[C@H](NC(=O)[C@H](Cc4ccc(O)cc4I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3350912	218309	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	44388123	175965	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1681	21	18	21	0.2	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL440618	175965	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1681	21	18	21	0.2	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3I)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL2371051	216783	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2cccc3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm0302445
	CHEMBL1824056	215819	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyDisplacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm200307v
	44388120	185003	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1696	22	21	22	-1.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC(=O)NCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL4649895	185003	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1696	22	21	22	-1.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC(=O)NCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL414100	219888	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]3CCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	44388037	167758	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1659	18	18	20	0.0	CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@@H]3CCCCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	CHEMBL411600	167758	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1659	18	18	20	0.0	CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@@H]3CCCCCCNC(=O)CC[C@@H](NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049519m
	25188218	19336	1	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL1186753	19336	1	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	CHEMBL476240	19336	1	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	11	4	4	4.2	C[C@@H](NC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)c1ccccc1	10.1021/jm801205x
	44388132	104064	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1696	22	21	22	-1.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL269023	104064	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1696	22	21	22	-1.3	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	11389178	122238	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1136	15	14	14	0.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL3350900	122238	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1136	15	14	14	0.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	44368019	17037	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1136	12	12	15	1.1	C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)N(C(=O)c2ccccc2)C(=O)N(C)[C@H](O)NC(=O)[C@@H](N)CSSCCNC(=O)[C@@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL1161328	17037	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1136	12	12	15	1.1	C[C@@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccc2)NC(=O)N(C(=O)c2ccccc2)C(=O)N(C)[C@H](O)NC(=O)[C@@H](N)CSSCCNC(=O)[C@@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	162651887	187050	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Displacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assayDisplacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assay	ChEMBL	924	25	12	12	-0.1	CCC(NC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](N)CC(N)=O)C(N)=O	10.1021/acs.jmedchem.6b00164
	CHEMBL4750625	187050	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Displacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assayDisplacement of [125I-Tyr11]-SS14 from human SSTR1 expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assay	ChEMBL	924	25	12	12	-0.1	CCC(NC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](N)CC(N)=O)C(N)=O	10.1021/acs.jmedchem.6b00164
	CHEMBL427658	220141	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL411860	219740	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	CHEMBL264839	217410	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)N(C)C(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL438630	220563	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049519m
	CHEMBL412624	219790	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3349616	218221	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970730q
	44388119	167156	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1682	22	21	22	-1.7	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL411109	167156	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1682	22	21	22	-1.7	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCC(=O)NCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	25189325	19218	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	3.6	NCCCC[C@@H](C(=O)NCCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1186056	19218	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	3.6	NCCCC[C@@H](C(=O)NCCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL447455	19218	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	565	12	4	4	3.6	NCCCC[C@@H](C(=O)NCCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL268448	217533	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)N(C)C(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	11159133	122240	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1152	15	15	15	0.1	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	CHEMBL3350904	122240	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1152	15	15	15	0.1	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	10.1021/jm030245x
	25189052	19444	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	676	10	5	6	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC(n3c(=O)[nH]c4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL1187345	19444	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	676	10	5	6	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC(n3c(=O)[nH]c4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL499681	19444	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	676	10	5	6	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)N2CCC(n3c(=O)[nH]c4ccccc43)CC2)C1=O	10.1021/jm801205x
	CHEMBL455760	220787	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst1 receptor expressed in CHOK1 cells by autoradiographyDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst1 receptor expressed in CHOK1 cells by autoradiography	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2c[nH]c(C(=O)O)c2)CCSSCC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm701445q
	CHEMBL406373	219385	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.	ChEMBL		None	None	None		C[C@@H](c1ccc2ccccc2c1)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccc(I)cc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0302445
	44388109	168536	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1653	22	20	21	-0.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL413924	168536	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1653	22	20	21	-0.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCC[C@@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL505128	220967	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1SSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	CHEMBL436962	220479	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O	10.1021/jm049519m
	CHEMBL3122128	217885	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisDisplacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysis	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)COCCOCCNC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1016/j.ejmech.2013.12.003
	CHEMBL414717	219929	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm049520l
	CHEMBL408654	219505	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCNC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	42637632	67049	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1334	20	11	14	5.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL174206	67049	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1334	20	11	14	5.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@@H](Cc3ccc4ccccc4c3)C(N)=O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL384855	219117	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@H]2C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](Cc3ccc(O)cc3I)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N2C)cc1	10.1021/jm049520l
	25187953	19461	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	725	10	4	6	3.8	CS(=O)(=O)N1CC2(CCN(C(=O)N[C@@H]3Cc4c([nH]c5ccccc45)CN([C@@H](CCCCN)C(=O)NCc4ccccc4)C3=O)CC2)c2ccccc21	10.1021/jm801205x
	CHEMBL1187458	19461	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	725	10	4	6	3.8	CS(=O)(=O)N1CC2(CCN(C(=O)N[C@@H]3Cc4c([nH]c5ccccc45)CN([C@@H](CCCCN)C(=O)NCc4ccccc4)C3=O)CC2)c2ccccc21	10.1021/jm801205x
	CHEMBL503379	19461	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	725	10	4	6	3.8	CS(=O)(=O)N1CC2(CCN(C(=O)N[C@@H]3Cc4c([nH]c5ccccc45)CN([C@@H](CCCCN)C(=O)NCc4ccccc4)C3=O)CC2)c2ccccc21	10.1021/jm801205x
	11457521	122237	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1136	15	14	14	0.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	CHEMBL3350892	122237	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL	1136	15	14	14	0.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	71460000	86434	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL2115143	86434	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	44368406	17039	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1022	9	11	12	1.1	C[C@@H]1NC(=O)N(C)[C@H](O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL1161332	17039	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandBinding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligand	ChEMBL	1022	9	11	12	1.1	C[C@@H]1NC(=O)N(C)[C@H](O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030243c
	CHEMBL3350908	218306	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](c1c[nH]c2ccccc12)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm030245x
	25187685	19242	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	648	11	4	5	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C2CCN(C(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	CHEMBL1186206	19242	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	648	11	4	5	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C2CCN(C(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	CHEMBL454202	19242	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	648	11	4	5	3.9	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)C2CCN(C(=O)c3ccccc3)CC2)C1=O	10.1021/jm801205x
	16738359	143961	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL374833	143961	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL453938	143961	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm801205x
	16738359	143961	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL374833	143961	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL453938	143961	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorDisplacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptor	ChEMBL	641	13	4	4	5.6	NCCCC[C@@H](C(=O)NCc1ccccc1)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)C1=O	10.1021/jm070246f
	CHEMBL440074	220638	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2I)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	44388107	165879	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1653	22	20	21	-0.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL409747	165879	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1	ChEMBL	1653	22	20	21	-0.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]3CCC(=O)NCCCCC[C@H](NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]([C@@H](C)O)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](Cc2ccccc2)C(=O)N3)cc1	10.1021/jm049519m
	CHEMBL3349598	218206	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity towards cloned human somatostatin 1 (hsst) receptorBinding affinity towards cloned human somatostatin 1 (hsst) receptor	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm970730q
	11642413	23872	0	None	-	0	Human	5.0	pIC50	=	5.0	Binding	Displacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cellsDisplacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cells	ChEMBL	544	11	3	7	3.9	CS[C@@H]1O[C@H](COCc2ccc(Cl)cc2)[C@@H](O)[C@@H](OCc2ccc3ccccc3c2)[C@H]1NC(=O)CCN	10.1021/jm1002777
	CHEMBL1254967	23872	0	None	-	0	Human	5.0	pIC50	=	5.0	Binding	Displacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cellsDisplacement of [125I]iodotyrosyl from human SST1 receptor expressed in CHO cells	ChEMBL	544	11	3	7	3.9	CS[C@@H]1O[C@H](COCc2ccc(Cl)cc2)[C@@H](O)[C@@H](OCc2ccc3ccccc3c2)[C@H]1NC(=O)CCN	10.1021/jm1002777
	CHEMBL504087	220952	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptorDisplacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human cloned sst1 receptor	ChEMBL		None	None	None		CC(=O)N[C@@H]1CCSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm701444y
	24777672	101687	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptorDisplacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptor	ChEMBL	1027	18	12	11	1.0	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1	10.1021/jm070886i
	CHEMBL254210	101687	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptorDisplacement of [125I](Leu8,D-Trp22,Tyr25)-SRIF28 from human sst1 receptor	ChEMBL	1027	18	12	11	1.0	C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1C/C=C\C[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1	10.1021/jm070886i
	25188496	19307	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	476	9	3	5	2.5	COC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL1186630	19307	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	476	9	3	5	2.5	COC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	CHEMBL473160	19307	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cellsDisplacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst1 receptor expressed in chinese hamster CCL39 cells	ChEMBL	476	9	3	5	2.5	COC(=O)[C@H](CCCCN)N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O	10.1021/jm801205x
	42637137	202668	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	CHEMBL558935	202668	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyDisplacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiography	ChEMBL	1238	19	12	15	2.0	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](N(C)C(=O)c3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](NC(=O)[C@H](N)Cc3ccc(O)cc3)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC2=O)cc1	10.1021/jm801314f
	71460000	86434	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL2115143	86434	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.Tested for ability to bind to 20 uM thick cryostat sections of a membrane pellet of cells transfected with human cloned somatostatin (sst) receptor subtype 1.	ChEMBL	1644	25	18	20	1.9	CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](NC(=O)CCc3ccc(O)cc3)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1	10.1021/jm010037+
	CHEMBL3350890	218292	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(N)=O)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm030245x
	9849682	101727	0	None	8	10	Rat	9.7	pKd	=	9.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	523	2	1	5	2.9	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254500	101727	0	None	8	10	Rat	9.7	pKd	=	9.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	523	2	1	5	2.9	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441671	161763	0	None	23988	2	Rat	9.7	pKd	=	9.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	542	4	0	10	1.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OS(C)(=O)=O)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL401290	161763	0	None	23988	2	Rat	9.7	pKd	=	9.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	542	4	0	10	1.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OS(C)(=O)=O)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447075	101360	0	None	16218	2	Rat	9.6	pKd	=	9.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	507	2	1	7	3.5	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252032	101360	0	None	16218	2	Rat	9.6	pKd	=	9.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	507	2	1	7	3.5	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447049	101729	0	None	93325	2	Rat	9.6	pKd	=	9.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	3	1	5	3.4	CCn1c(N2CCN(C(=O)[C@@H]3C[C@@H]4c5cccc6[nH]c(Br)c(c56)C[C@H]4N(C)C3)CC2)cccc1=O	10.1016/j.bmcl.2007.12.030
	CHEMBL254505	101729	0	None	93325	2	Rat	9.6	pKd	=	9.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	3	1	5	3.4	CCn1c(N2CCN(C(=O)[C@@H]3C[C@@H]4c5cccc6[nH]c(Br)c(c56)C[C@H]4N(C)C3)CC2)cccc1=O	10.1016/j.bmcl.2007.12.030
	2019	10447	0	None	-4	10	Human	9.5	pKd	=	9.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.8b02036
	44386062	10447	0	None	-4	10	Human	9.5	pKd	=	9.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.8b02036
	CHEMBL440072	10447	0	None	-4	10	Human	9.5	pKd	=	9.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.8b02036
	44565159	201670	0	None	6	5	Rat	9.5	pKd	=	9.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	497	7	0	7	4.5	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL540705	201670	0	None	6	5	Rat	9.5	pKd	=	9.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	497	7	0	7	4.5	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44447073	101325	0	None	3	10	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	534	2	1	6	3.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL251835	101325	0	None	3	10	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	534	2	1	6	3.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447076	101361	0	None	12302	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	551	2	1	7	3.6	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252033	101361	0	None	12302	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	551	2	1	7	3.6	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447048	161767	0	None	31622	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	5	3.3	CCn1c(N2CCN(C(=O)[C@@H]3C[C@@H]4c5cccc6[nH]c(Cl)c(c56)C[C@H]4N(C)C3)CC2)cccc1=O	10.1016/j.bmcl.2007.12.030
	CHEMBL401309	161767	0	None	31622	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	5	3.3	CCn1c(N2CCN(C(=O)[C@@H]3C[C@@H]4c5cccc6[nH]c(Cl)c(c56)C[C@H]4N(C)C3)CC2)cccc1=O	10.1016/j.bmcl.2007.12.030
	44447045	101726	0	None	125892	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	479	2	1	5	2.8	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254499	101726	0	None	125892	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	479	2	1	5	2.8	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447071	160903	0	None	13182	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	490	2	1	6	3.7	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL398526	160903	0	None	13182	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	490	2	1	6	3.7	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441673	101309	0	None	9772	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	596	4	0	10	2.7	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251754	101309	0	None	9772	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	596	4	0	10	2.7	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44441665	175912	0	None	9120	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	528	5	0	8	2.3	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OS(C)(=O)=O)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL440236	175912	0	None	9120	2	Rat	9.4	pKd	=	9.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	528	5	0	8	2.3	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OS(C)(=O)=O)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447038	101448	0	None	16595	2	Rat	9.3	pKd	=	9.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	528	2	1	3	4.5	CN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252618	101448	0	None	16595	2	Rat	9.3	pKd	=	9.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	528	2	1	3	4.5	CN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	10162564	19312	0	None	9	8	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186652	19312	0	None	9	8	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL473763	19312	0	None	9	8	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441672	101308	0	None	3311	2	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	618	5	0	10	3.5	Cc1ccc(S(=O)(=O)Oc2cccc3c2C[C@H]2C[C@@H](C(=O)N4CCN(c5ccc6nsnc6n5)CC4)CN(C)[C@@H]2C3)cc1	10.1016/j.bmcl.2007.04.086
	CHEMBL251753	101308	0	None	3311	2	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	618	5	0	10	3.5	Cc1ccc(S(=O)(=O)Oc2cccc3c2C[C@H]2C[C@@H](C(=O)N4CCN(c5ccc6nsnc6n5)CC4)CN(C)[C@@H]2C3)cc1	10.1016/j.bmcl.2007.04.086
	44447069	101419	0	None	21379	2	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	484	2	1	3	4.4	CN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252428	101419	0	None	21379	2	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	484	2	1	3	4.4	CN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44564783	183704	0	None	10	4	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	484	8	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL461988	183704	0	None	10	4	Rat	9.2	pKd	=	9.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	484	8	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	2030	10444	10	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.078
	5311377	10444	10	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.078
	CHEMBL251541	10444	10	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.078
	2030	10444	10	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	5311377	10444	10	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	CHEMBL251541	10444	10	None	7	10	Rat	9.2	pKd	=	9.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	44565112	19531	0	None	3	6	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187847	19531	0	None	3	6	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL523814	19531	0	None	3	6	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44447043	101698	0	None	10232	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	445	2	1	5	2.2	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254288	101698	0	None	10232	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	445	2	1	5	2.2	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	17955460	183554	0	None	2	9	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	491	7	0	4	5.3	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL460542	183554	0	None	2	9	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	491	7	0	4	5.3	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44441661	101267	0	None	7079	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	492	5	0	6	3.8	CC(C)Oc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL251542	101267	0	None	7079	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	492	5	0	6	3.8	CC(C)Oc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44441678	100827	0	None	12022	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	506	4	0	9	2.3	COc1ccc(C=O)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248908	100827	0	None	12022	2	Rat	9.1	pKd	=	9.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	506	4	0	9	2.3	COc1ccc(C=O)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44564746	183740	0	None	7585	2	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	500	8	0	6	4.9	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL462336	183740	0	None	7585	2	Rat	9.1	pKd	=	9.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	500	8	0	6	4.9	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44564815	196531	0	None	1905	2	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	498	9	0	5	5.2	CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL515907	196531	0	None	1905	2	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	498	9	0	5	5.2	CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44447042	101697	0	None	13489	2	Rat	9.0	pKd	=	9.0	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	542	3	1	3	4.9	CCN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254287	101697	0	None	13489	2	Rat	9.0	pKd	=	9.0	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	542	3	1	3	4.9	CCN1C[C@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447074	101326	0	None	2951	2	Rat	9.0	pKd	=	9.0	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	473	2	1	7	2.9	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL251836	101326	0	None	2951	2	Rat	9.0	pKd	=	9.0	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	473	2	1	7	2.9	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44565114	19408	0	None	-	1	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	480	7	0	6	3.9	CN(CCC(=O)N1CCN(c2ccc3nccn3n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187144	19408	0	None	-	1	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	480	7	0	6	3.9	CN(CCC(=O)N1CCN(c2ccc3nccn3n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491497	19408	0	None	-	1	Rat	9.0	pKd	=	9.0	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	480	7	0	6	3.9	CN(CCC(=O)N1CCN(c2ccc3nccn3n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441677	100826	0	None	5248	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	556	3	0	8	3.2	COc1ccc(Br)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248907	100826	0	None	5248	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	556	3	0	8	3.2	COc1ccc(Br)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	23656025	100869	0	None	8511	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	450	4	1	6	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL249113	100869	0	None	8511	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	450	4	1	6	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44441670	161423	0	None	3981	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	554	5	0	8	4.0	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OCc3ccccc3)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL399464	161423	0	None	3981	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	554	5	0	8	4.0	CN1C[C@H](C(=O)N2CCN(c3ccc4nsnc4n3)CC2)C[C@@H]2Cc3c(cccc3OCc3ccccc3)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447073	101325	0	None	-3	10	Human	8.9	pKd	=	8.9	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	534	2	1	6	3.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL251835	101325	0	None	-3	10	Human	8.9	pKd	=	8.9	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	534	2	1	6	3.8	CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441669	100789	0	None	4677	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	478	3	0	8	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL248715	100789	0	None	4677	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	478	3	0	8	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441669	100789	0	None	4677	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	478	3	0	8	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248715	100789	0	None	4677	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	478	3	0	8	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44447064	161149	0	None	7079	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	5	4.0	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL398712	161149	0	None	7079	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	5	4.0	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441899	161114	0	None	8511	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4[N+](=O)[O-])CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL398681	161114	0	None	8511	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4[N+](=O)[O-])CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441900	101075	0	None	5128	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc([N+](=O)[O-])c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250498	101075	0	None	5128	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc([N+](=O)[O-])c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447066	101388	0	None	5370	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	3	1	5	4.1	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252229	101388	0	None	5370	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	3	1	5	4.1	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441659	161459	0	None	7762	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	538	4	0	7	2.7	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL399658	161459	0	None	7762	2	Rat	8.9	pKd	=	8.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	538	4	0	7	2.7	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44441666	161499	0	None	2290	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	582	5	0	8	3.2	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL399843	161499	0	None	2290	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	582	5	0	8	3.2	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OS(=O)(=O)C(F)(F)F)C[C@H]21	10.1016/j.bmcl.2007.04.086
	17955460	183554	0	None	-2	9	Human	8.8	pKd	=	8.8	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	491	7	0	4	5.3	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL460542	183554	0	None	-2	9	Human	8.8	pKd	=	8.8	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	491	7	0	4	5.3	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44564859	19496	0	None	-	1	Rat	8.8	pKd	=	8.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccc(Cl)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187680	19496	0	None	-	1	Rat	8.8	pKd	=	8.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccc(Cl)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL515113	19496	0	None	-	1	Rat	8.8	pKd	=	8.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccc(Cl)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441884	101168	0	None	2041	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	3	0	7	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nonc5c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250922	101168	0	None	2041	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	3	0	7	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nonc5c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	9849682	101727	0	None	-8	10	Human	8.8	pKd	=	8.8	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	523	2	1	5	2.9	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL254500	101727	0	None	-8	10	Human	8.8	pKd	=	8.8	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	523	2	1	5	2.9	CN1C[C@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441919	161549	0	None	3019	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	542	5	0	8	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4S(C)(=O)=O)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400137	161549	0	None	3019	2	Rat	8.8	pKd	=	8.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	542	5	0	8	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4S(C)(=O)=O)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564907	19304	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	6.2	CN(CCC(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186613	19304	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	6.2	CN(CCC(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL472751	19304	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	6.2	CN(CCC(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44565010	19410	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2ccc(F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187146	19410	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2ccc(F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491507	19410	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2ccc(F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441897	100998	0	None	3715	2	Rat	8.7	pKd	=	8.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	444	3	0	5	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249930	100998	0	None	3715	2	Rat	8.7	pKd	=	8.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	444	3	0	5	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	2030	10444	10	None	-13	10	Human	8.0	pKd	=	8.0	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	5311377	10444	10	None	-13	10	Human	8.0	pKd	=	8.0	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	CHEMBL251541	10444	10	None	-13	10	Human	8.0	pKd	=	8.0	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	10.1016/j.bmcl.2007.04.086
	44441886	161541	0	None	398	2	Rat	8.0	pKd	=	8.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	3	0	7	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400099	161541	0	None	398	2	Rat	8.0	pKd	=	8.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	3	0	7	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46880580	12319	0	None	-346	2	Human	6.0	pKd	=	6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2CC3CCCCC3C(C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076657	12319	0	None	-346	2	Human	6.0	pKd	=	6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2CC3CCCCC3C(C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL385409	219128	0	None	-97	4	Human	6.0	pKd	=	6	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL437093	220484	0	None	-16	5	Human	6.0	pKd	=	6	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N(C)[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL438471	220552	0	None	-125	4	Human	6.0	pKd	=	6	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N(C)[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	46880574	12869	0	None	-1	2	Human	7.0	pKd	=	7.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	494	7	0	7	3.6	CC(Cc1ccc2c(c1)OCO2)CN1CCCC(C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1080734	12869	0	None	-1	2	Human	7.0	pKd	=	7.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	494	7	0	7	3.6	CC(Cc1ccc2c(c1)OCO2)CN1CCCC(C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	44441871	101045	0	None	190	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	488	3	0	5	3.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250313	101045	0	None	190	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	488	3	0	5	3.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441873	101202	0	None	63	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	526	6	0	6	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(OCc5ccccc5)n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251116	101202	0	None	63	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	526	6	0	6	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(OCc5ccccc5)n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441932	101236	0	None	4	2	Rat	5.0	pKd	=	5.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	343	2	1	4	1.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCNCC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251301	101236	0	None	4	2	Rat	5.0	pKd	=	5.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	343	2	1	4	1.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCNCC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441918	173650	0	None	44	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	532	4	0	6	4.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cc4[N+](=O)[O-])CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL428583	173650	0	None	44	2	Rat	7.0	pKd	=	7.0	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	532	4	0	6	4.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cc4[N+](=O)[O-])CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564703	197276	0	None	446	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	510	8	0	5	5.3	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2C=Cc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL517921	197276	0	None	446	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	510	8	0	5	5.3	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2C=Cc2ccccc21	10.1016/j.bmcl.2009.01.072
	44447029	177808	0	None	-	1	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	535	5	1	4	4.8	CCCCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL445673	177808	0	None	-	1	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	535	5	1	4	4.8	CCCCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	46865536	18691	0	None	-151	7	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076623	18691	0	None	-151	7	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1182658	18691	0	None	-151	7	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	44564745	183739	0	None	478	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	516	8	0	6	5.3	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Sc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL462335	183739	0	None	478	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	516	8	0	6	5.3	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Sc2ccccc21	10.1016/j.bmcl.2009.01.072
	44447009	101543	0	None	-	1	Rat	7.9	pKd	=	7.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	449	2	1	4	3.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253234	101543	0	None	-	1	Rat	7.9	pKd	=	7.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	449	2	1	4	3.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	46880573	12868	0	None	-1	2	Human	6.9	pKd	=	6.9	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	510	6	0	5	5.2	O=C(C1CCCN(CCC2c3ccccc3-c3ccccc32)C1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2010.01.063
	CHEMBL1080733	12868	0	None	-1	2	Human	6.9	pKd	=	6.9	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	510	6	0	5	5.2	O=C(C1CCCN(CCC2c3ccccc3-c3ccccc32)C1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2010.01.063
	CHEMBL407209	219426	1	None	-1949	4	Human	5.9	pKd	=	5.9	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N(C)[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL384836	219116	0	None	-74	5	Human	5.9	pKd	=	5.9	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1C)C(N)=O	10.1021/jm000361p
	44564814	186816	0	None	602	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	486	10	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC(c1ccccc1)c1ccccc1	10.1016/j.bmcl.2009.01.072
	CHEMBL474752	186816	0	None	602	2	Rat	7.9	pKd	=	7.9	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	486	10	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC(c1ccccc1)c1ccccc1	10.1016/j.bmcl.2009.01.072
	44441680	100868	0	None	11	2	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@@H]1C[C@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL249112	100868	0	None	11	2	Rat	5.9	pKd	=	5.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	464	4	0	6	3.0	COc1cccc2c1C[C@@H]1C[C@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL2370166	216584	0	None	-977	5	Human	4.9	pKd	=	4.9	Binding	In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.	ChEMBL		None	None	None		C[C@@H](c1ccccc1)N1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCNC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C1=O	10.1021/jm970393l
	46865535	12311	0	None	-407	7	Human	5.9	pKd	=	5.9	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	550	6	0	5	5.7	Cc1nc2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2o1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076622	12311	0	None	-407	7	Human	5.9	pKd	=	5.9	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	550	6	0	5	5.7	Cc1nc2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2o1	10.1016/j.bmcl.2010.01.063
	44447006	101541	0	None	1258	2	Rat	7.9	pKd	=	7.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	415	2	1	4	2.9	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253232	101541	0	None	1258	2	Rat	7.9	pKd	=	7.9	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	415	2	1	4	2.9	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447034	161536	0	None	-	1	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	5	1	5	3.7	COCCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL400066	161536	0	None	-	1	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	5	1	5	3.7	COCCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441667	161720	0	None	457	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	459	3	0	6	2.9	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(C#N)cccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL401091	161720	0	None	457	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	459	3	0	6	2.9	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(C#N)cccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	44441906	101126	0	None	57	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	4	0	5	3.3	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250705	101126	0	None	57	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	4	0	5	3.3	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441909	100996	0	None	10	2	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	462	4	1	5	2.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(N)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249892	100996	0	None	10	2	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	462	4	1	5	2.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(N)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46865536	18691	0	None	-199	7	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076623	18691	0	None	-199	7	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1182658	18691	0	None	-199	7	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	553	6	0	6	5.2	C[C@@H](Cc1ccc2nsnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	44441660	101240	0	None	204	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	390	2	0	4	2.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2Cc3ccccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251335	101240	0	None	204	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	390	2	0	4	2.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2Cc3ccccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447014	101604	0	None	338	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	541	2	1	4	3.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(I)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253653	101604	0	None	338	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	541	2	1	4	3.5	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(I)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441908	101163	0	None	91	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	4	0	6	2.9	COC(=O)c1ccc(N2CCN(C(=O)[C@@H]3C[C@@H]4Cc5c(cccc5OC)C[C@H]4N(C)C3)CC2)cc1	10.1016/j.bmcl.2007.04.078
	CHEMBL250900	101163	0	None	91	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	4	0	6	2.9	COC(=O)c1ccc(N2CCN(C(=O)[C@@H]3C[C@@H]4Cc5c(cccc5OC)C[C@H]4N(C)C3)CC2)cc1	10.1016/j.bmcl.2007.04.078
	46880853	12337	0	None	-147	2	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	536	6	0	5	5.4	C[C@@H](Cc1ccc2ocnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076718	12337	0	None	-147	2	Human	5.8	pKd	=	5.8	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	536	6	0	5	5.4	C[C@@H](Cc1ccc2ocnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	44447026	101355	0	None	46	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	479	2	2	4	3.3	O=C([C@H]1CN[C@@H]2Cc3c(Br)[nH]c4cccc(c34)[C@H]2C1)N1CCN(c2ccccn2)CC1	10.1016/j.bmcl.2007.12.030
	CHEMBL252002	101355	0	None	46	2	Rat	6.8	pKd	=	6.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	479	2	2	4	3.3	O=C([C@H]1CN[C@@H]2Cc3c(Br)[nH]c4cccc(c34)[C@H]2C1)N1CCN(c2ccccn2)CC1	10.1016/j.bmcl.2007.12.030
	44441910	100997	0	None	11	2	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	518	6	0	5	3.6	CCN(CC)C(=O)c1ccc(N2CCN(C(=O)[C@@H]3C[C@@H]4Cc5c(cccc5OC)C[C@H]4N(C)C3)CC2)cc1	10.1016/j.bmcl.2007.04.078
	CHEMBL249893	100997	0	None	11	2	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	518	6	0	5	3.6	CCN(CC)C(=O)c1ccc(N2CCN(C(=O)[C@@H]3C[C@@H]4Cc5c(cccc5OC)C[C@H]4N(C)C3)CC2)cc1	10.1016/j.bmcl.2007.04.078
	44441658	101239	0	None	588	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251334	101239	0	None	588	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441658	101239	0	None	588	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL251334	101239	0	None	588	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44564903	19322	0	None	-	1	Rat	7.8	pKd	=	7.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2cccc(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186691	19322	0	None	-	1	Rat	7.8	pKd	=	7.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2cccc(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL474745	19322	0	None	-	1	Rat	7.8	pKd	=	7.8	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2cccc(Cl)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441890	101237	0	None	1047	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4F)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251311	101237	0	None	1047	2	Rat	7.8	pKd	=	7.8	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccccc4F)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447032	101641	0	None	-	1	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	549	5	1	4	5.1	CC(C)CCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253880	101641	0	None	-	1	Rat	5.8	pKd	=	5.8	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	549	5	1	4	5.1	CC(C)CCN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44564702	196647	0	None	190	2	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	512	8	0	5	4.9	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2CCc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL516837	196647	0	None	190	2	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	512	8	0	5	4.9	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2CCc2ccccc21	10.1016/j.bmcl.2009.01.072
	44441662	101268	0	None	416	2	Rat	7.7	pKd	=	7.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	450	3	1	6	2.7	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(O)cccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251543	101268	0	None	416	2	Rat	7.7	pKd	=	7.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	450	3	1	6	2.7	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(O)cccc3C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447078	101392	0	None	2	7	Rat	6.7	pKd	=	6.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	534	2	1	6	3.8	CN1C[C@@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252232	101392	0	None	2	7	Rat	6.7	pKd	=	6.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	534	2	1	6	3.8	CN1C[C@@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	44441867	101020	0	None	9	2	Rat	5.7	pKd	=	5.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccncc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250111	101020	0	None	9	2	Rat	5.7	pKd	=	5.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	420	3	0	5	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccncc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447052	161730	0	None	112	2	Rat	7.7	pKd	=	7.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	448	2	1	3	4.1	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL401130	161730	0	None	112	2	Rat	7.7	pKd	=	7.7	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	448	2	1	3	4.1	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	46880856	12333	0	None	-66	2	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	539	8	1	5	5.1	CCNc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076711	12333	0	None	-66	2	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	539	8	1	5	5.1	CCNc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	44447077	101391	0	None	-4	7	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	523	2	1	5	2.9	CN1C[C@@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252231	101391	0	None	-4	7	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	523	2	1	5	2.9	CN1C[C@@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	44565159	201670	0	None	-6	5	Human	8.7	pKd	=	8.7	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	497	7	0	7	4.5	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL540705	201670	0	None	-6	5	Human	8.7	pKd	=	8.7	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	497	7	0	7	4.5	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2Oc2ccccc21	10.1016/j.bmcl.2009.01.072
	44565064	19405	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	470	7	0	5	3.6	CN(CCC(=O)N1CCN(c2cccc(=O)n2C)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187127	19405	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	470	7	0	5	3.6	CN(CCC(=O)N1CCN(c2cccc(=O)n2C)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491144	19405	0	None	-	1	Rat	8.7	pKd	=	8.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	470	7	0	5	3.6	CN(CCC(=O)N1CCN(c2cccc(=O)n2C)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44447019	101640	0	None	3548	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	461	3	1	5	3.6	CSc1[nH]c2cccc3c2c1C[C@@H]1[C@@H]3C[C@@H](C(=O)N2CCN(c3ccccn3)CC2)CN1C	10.1016/j.bmcl.2007.12.030
	CHEMBL253879	101640	0	None	3548	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	461	3	1	5	3.6	CSc1[nH]c2cccc3c2c1C[C@@H]1[C@@H]3C[C@@H](C(=O)N2CCN(c3ccccn3)CC2)CN1C	10.1016/j.bmcl.2007.12.030
	44565112	19531	0	None	-3	6	Human	8.6	pKd	=	8.6	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187847	19531	0	None	-3	6	Human	8.6	pKd	=	8.6	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL523814	19531	0	None	-3	6	Human	8.6	pKd	=	8.6	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	481	7	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc3nonc3c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441885	101203	0	None	3630	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	3	0	7	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5nsnc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251120	101203	0	None	3630	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	477	3	0	7	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5nsnc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	23656026	101041	0	None	-3	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	455	3	0	4	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250304	101041	0	None	-3	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	455	3	0	4	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441916	161548	0	None	5888	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	462	3	0	5	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(F)c4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400136	161548	0	None	5888	2	Rat	8.6	pKd	=	8.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	462	3	0	5	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(F)c4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	9871544	20988	3	None	-416	11	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076624	20988	3	None	-416	11	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1198948	20988	3	None	-416	11	Human	5.7	pKd	=	5.7	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	44441921	101127	0	None	165	2	Rat	6.7	pKd	=	6.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	434	3	0	5	2.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250713	101127	0	None	165	2	Rat	6.7	pKd	=	6.7	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	434	3	0	5	2.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCCN(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44565068	19520	0	None	-	1	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	440	7	0	4	4.3	CN(CCC(=O)N1CCN(c2ccncc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187808	19520	0	None	-	1	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	440	7	0	4	4.3	CN(CCC(=O)N1CCN(c2ccncc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL522135	19520	0	None	-	1	Rat	7.7	pKd	=	7.7	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	440	7	0	4	4.3	CN(CCC(=O)N1CCN(c2ccncc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441902	161654	0	None	562	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	487	3	0	4	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(C(F)(F)F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400709	161654	0	None	562	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	487	3	0	4	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(C(F)(F)F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564905	19303	0	None	-	1	Rat	7.6	pKd	=	7.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccccc2Cl)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186612	19303	0	None	-	1	Rat	7.6	pKd	=	7.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccccc2Cl)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL472750	19303	0	None	-	1	Rat	7.6	pKd	=	7.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	473	7	0	3	5.5	CN(CCC(=O)N1CCN(c2ccccc2Cl)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	46880581	12320	0	None	-21	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076658	12320	0	None	-21	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	46880855	12332	0	None	-165	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	540	8	0	5	5.0	CCOc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076710	12332	0	None	-165	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	540	8	0	5	5.0	CCOc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	44447037	101447	0	None	-	1	Rat	5.6	pKd	=	5.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	5	2	5	3.4	O=C([C@@H]1C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]2N(CCCO)C1)N1CCN(c2ccccn2)CC1	10.1016/j.bmcl.2007.12.030
	CHEMBL252617	101447	0	None	-	1	Rat	5.6	pKd	=	5.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	537	5	2	5	3.4	O=C([C@@H]1C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]2N(CCCO)C1)N1CCN(c2ccccn2)CC1	10.1016/j.bmcl.2007.12.030
	44447016	101605	0	None	35	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	431	2	2	5	2.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(O)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253654	101605	0	None	35	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	431	2	2	5	2.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(O)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	46880576	12315	0	None	-1	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@@H]21	10.1016/j.bmcl.2010.01.063
	CHEMBL1076653	12315	0	None	-1	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@@H]21	10.1016/j.bmcl.2010.01.063
	44441663	101266	0	None	660	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	534	4	0	7	3.9	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OC(=O)C(C)(C)C)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251529	101266	0	None	660	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	534	4	0	7	3.9	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OC(=O)C(C)(C)C)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44441923	101128	0	None	85	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	478	4	0	6	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250715	101128	0	None	85	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	478	4	0	6	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	20597810	12331	0	None	-245	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	547	6	0	5	5.2	C[C@@H](Cc1ccc2nccnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076709	12331	0	None	-245	2	Human	5.6	pKd	=	5.6	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	547	6	0	5	5.2	C[C@@H](Cc1ccc2nccnc2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	44447023	101320	0	None	6	2	Rat	5.6	pKd	=	5.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	477	3	1	5	2.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c([S+](C)[O-])c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL251801	101320	0	None	6	2	Rat	5.6	pKd	=	5.6	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	477	3	1	5	2.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c([S+](C)[O-])c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441879	101131	0	None	75	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	470	3	0	5	3.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5ccccc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250724	101131	0	None	75	2	Rat	7.6	pKd	=	7.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	470	3	0	5	3.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5ccccc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564786	183595	0	None	60	2	Rat	6.6	pKd	=	6.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	446	8	0	5	4.0	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCc1ccc2ccccc2c1	10.1016/j.bmcl.2009.01.072
	CHEMBL460934	183595	0	None	60	2	Rat	6.6	pKd	=	6.6	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	446	8	0	5	4.0	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCc1ccc2ccccc2c1	10.1016/j.bmcl.2009.01.072
	44441903	101124	0	None	18	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	487	3	0	4	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250703	101124	0	None	18	2	Rat	6.6	pKd	=	6.6	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	487	3	0	4	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(F)(F)F)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441880	176006	0	None	19	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	470	3	0	5	3.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc5ccccc5cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL440962	176006	0	None	19	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	470	3	0	5	3.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc5ccccc5cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564744	183722	0	None	630	2	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	498	8	0	5	4.7	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Cc2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL462159	183722	0	None	630	2	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	498	8	0	5	4.7	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2Cc2ccccc21	10.1016/j.bmcl.2009.01.072
	44441917	101042	0	None	1348	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	489	4	0	7	2.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250305	101042	0	None	1348	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	489	4	0	7	2.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4C#N)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564949	19311	0	None	-	1	Rat	8.5	pKd	=	8.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)cc2F)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186651	19311	0	None	-	1	Rat	8.5	pKd	=	8.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)cc2F)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL473762	19311	0	None	-	1	Rat	8.5	pKd	=	8.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)cc2F)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441893	100968	0	None	6456	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249723	100968	0	None	6456	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(F)c4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441894	161690	0	None	7762	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(F)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400907	161690	0	None	7762	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	437	3	0	4	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(F)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441870	175910	0	None	2884	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	445	3	0	6	2.3	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C#N)cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL440233	175910	0	None	2884	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	445	3	0	6	2.3	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C#N)cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441674	161396	0	None	3890	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	498	4	0	6	3.6	COc1ccc(Cl)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL399267	161396	0	None	3890	2	Rat	8.5	pKd	=	8.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	498	4	0	6	3.6	COc1ccc(Cl)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44564909	19305	0	None	-	1	Rat	8.4	pKd	=	8.4	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2cccc(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186614	19305	0	None	-	1	Rat	8.4	pKd	=	8.4	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2cccc(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL472752	19305	0	None	-	1	Rat	8.4	pKd	=	8.4	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	457	7	0	3	5.0	CN(CCC(=O)N1CCN(c2cccc(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441883	101167	0	None	999	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	3	0	7	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5nonc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250921	101167	0	None	999	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	461	3	0	7	2.6	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5nonc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447062	101357	0	None	812	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	459	3	1	5	3.4	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252029	101357	0	None	812	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	459	3	1	5	3.4	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441926	101165	0	None	77	2	Rat	7.5	pKd	=	7.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	417	3	0	4	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250914	101165	0	None	77	2	Rat	7.5	pKd	=	7.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	417	3	0	4	3.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ccccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447025	161726	0	None	25	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	6	2.3	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(S(C)(=O)=O)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL401108	161726	0	None	25	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	3	1	6	2.3	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(S(C)(=O)=O)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44564952	19288	0	None	-	1	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2ccc(C(F)(F)F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186578	19288	0	None	-	1	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2ccc(C(F)(F)F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL470500	19288	0	None	-	1	Rat	7.5	pKd	=	7.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2ccc(C(F)(F)F)cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	155544425	180161	0	None	-14125	5	Human	6.5	pKd	=	6.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL	1785	27	15	26	3.3	COc1cc2cc(c1Cl)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCSSC[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O)[C@@]1(C)O[C@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@H](OC)/C=C/C=C(\C)C2	10.1021/acs.jmedchem.8b02036
	CHEMBL4527856	180161	0	None	-14125	5	Human	6.5	pKd	=	6.5	Binding	Displacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 minsDisplacement of [125I]somatostatin from human SSTR1 expressed in CHO-K1 cell membranes after 120 mins	ChEMBL	1785	27	15	26	3.3	COc1cc2cc(c1Cl)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCSSC[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc3ccccc3)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O)[C@@]1(C)O[C@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@H](OC)/C=C/C=C(\C)C2	10.1021/acs.jmedchem.8b02036
	CHEMBL407571	219448	0	None	-309	4	Human	6.5	pKd	=	6.5	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		CN[C@H](Cc1ccccc1)C(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm000361p
	44564784	183720	0	None	43	2	Rat	6.5	pKd	=	6.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	485	8	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCn1c2ccccc2c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL462157	183720	0	None	43	2	Rat	6.5	pKd	=	6.5	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	485	8	0	6	4.4	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCn1c2ccccc2c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441679	100867	0	None	83	2	Rat	7.5	pKd	=	7.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	520	4	0	9	2.7	COc1ccc(C(C)=O)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL249111	100867	0	None	83	2	Rat	7.5	pKd	=	7.5	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	520	4	0	9	2.7	COc1ccc(C(C)=O)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nsnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44441882	101166	0	None	19	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	472	3	0	7	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc5nccnc5cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250920	101166	0	None	19	2	Rat	6.5	pKd	=	6.5	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	472	3	0	7	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc5nccnc5cn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL2370167	216585	0	None	-1621	5	Human	5.5	pKd	=	5.5	Binding	In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCNC(=O)[C@@H](N)Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)CN([C@H](C)c2ccccc2)C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970393l
	CHEMBL405421	219339	0	None	-363	4	Human	6.4	pKd	=	6.4	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](N(C)C(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	46880590	12312	0	None	2	2	Human	7.4	pKd	=	7.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	549	6	0	5	5.2	Cc1cn2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2n1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076627	12312	0	None	2	2	Human	7.4	pKd	=	7.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	549	6	0	5	5.2	Cc1cn2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2n1	10.1016/j.bmcl.2010.01.063
	46880582	12321	0	None	-295	2	Human	6.4	pKd	=	6.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076659	12321	0	None	-295	2	Human	6.4	pKd	=	6.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(CC(C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	44447058	161731	0	None	1412	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	482	2	1	3	4.8	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL401131	161731	0	None	1412	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	482	2	1	3	4.8	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]c(Cl)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44447011	101573	0	None	3715	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	2	1	4	3.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL253438	101573	0	None	3715	2	Rat	8.4	pKd	=	8.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	493	2	1	4	3.6	CN1C[C@H](C(=O)N2CCN(c3ccccn3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44565116	19409	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	483	7	0	5	4.6	CN(CCC(=O)N1CCN(c2ccc3c(c2)OCO3)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187145	19409	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	483	7	0	5	4.6	CN(CCC(=O)N1CCN(c2ccc3c(c2)OCO3)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491498	19409	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	483	7	0	5	4.6	CN(CCC(=O)N1CCN(c2ccc3c(c2)OCO3)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44565012	19411	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	464	7	0	4	4.7	CN(CCC(=O)N1CCN(c2ccccc2C#N)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187147	19411	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	464	7	0	4	4.7	CN(CCC(=O)N1CCN(c2ccccc2C#N)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491508	19411	0	None	-	1	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	464	7	0	4	4.7	CN(CCC(=O)N1CCN(c2ccccc2C#N)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441675	100790	0	None	1995	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	542	4	0	6	3.8	COc1ccc(Br)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248716	100790	0	None	1995	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	542	4	0	6	3.8	COc1ccc(Br)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44564816	196292	0	None	194	2	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	512	9	0	5	5.5	CC(C)N(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL514027	196292	0	None	194	2	Rat	8.3	pKd	=	8.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	512	9	0	5	5.5	CC(C)N(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441664	101306	0	None	3235	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	550	4	0	8	4.3	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OC(=O)OC(C)(C)C)C[C@H]21	10.1016/j.bmcl.2007.04.086
	CHEMBL251751	101306	0	None	3235	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	550	4	0	8	4.3	CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2Cc3c(cccc3OC(=O)OC(C)(C)C)C[C@H]21	10.1016/j.bmcl.2007.04.086
	44447077	101391	0	None	4	7	Rat	6.4	pKd	=	6.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	523	2	1	5	2.9	CN1C[C@@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252231	101391	0	None	4	7	Rat	6.4	pKd	=	6.4	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	523	2	1	5	2.9	CN1C[C@@H](C(=O)N2CCN(c3cccc(=O)n3C)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	46880583	12309	0	None	-194	2	Human	6.4	pKd	=	6.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(C[C@@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076620	12309	0	None	-194	2	Human	6.4	pKd	=	6.4	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(C[C@@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	44564857	185717	0	None	1	4	Rat	7.3	pKd	=	7.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	524	10	0	5	5.5	O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2009.01.072
	CHEMBL470331	185717	0	None	1	4	Rat	7.3	pKd	=	7.3	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	524	10	0	5	5.5	O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2009.01.072
	46865535	12311	0	None	-134	7	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	550	6	0	5	5.7	Cc1nc2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2o1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076622	12311	0	None	-134	7	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	550	6	0	5	5.7	Cc1nc2cc(C[C@H](C)CN3C[C@@H](C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)[C@H]4CCCC[C@H]4C3)ccc2o1	10.1016/j.bmcl.2010.01.063
	44441931	161601	0	None	19	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	433	4	0	4	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(Cc4ccccc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400386	161601	0	None	19	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	433	4	0	4	3.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(Cc4ccccc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL421362	220053	0	None	-1258	5	Human	5.3	pKd	=	5.3	Binding	In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970393l
	44441869	161649	0	None	58	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	421	3	0	6	1.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ncccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400677	161649	0	None	58	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	421	3	0	6	1.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ncccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46880575	12314	0	None	-3	2	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@@H]21	10.1016/j.bmcl.2010.01.063
	CHEMBL1076652	12314	0	None	-3	2	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@@H]21	10.1016/j.bmcl.2010.01.063
	44441927	101200	0	None	4	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	418	3	0	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ncccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251110	101200	0	None	4	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	418	3	0	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ncccn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441928	101201	0	None	4	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	474	3	1	5	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCC(n4c(=O)[nH]c5ccccc54)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251111	101201	0	None	4	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	474	3	1	5	3.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCC(n4c(=O)[nH]c5ccccc54)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	10162564	19312	0	None	-9	8	Human	8.3	pKd	=	8.3	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1186652	19312	0	None	-9	8	Human	8.3	pKd	=	8.3	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL473763	19312	0	None	-9	8	Human	8.3	pKd	=	8.3	Binding	Binding affinity to human sst1 receptorBinding affinity to human sst1 receptor	ChEMBL	475	7	0	3	5.1	CN(CCC(=O)N1CCN(c2ccc(F)c(F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44447060	201610	0	None	363	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	526	2	1	3	4.9	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL539415	201610	0	None	363	2	Rat	8.3	pKd	=	8.3	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat cortexDisplacement of [125I]SRIF14 from sst1 receptor in rat cortex	ChEMBL	526	2	1	3	4.9	CN1C[C@H](C(=O)N2CCN(c3ccc(Cl)cc3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21	10.1016/j.bmcl.2007.12.030
	44441881	161069	0	None	2454	2	Rat	8.2	pKd	=	8.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	472	3	0	7	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nccnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL398656	161069	0	None	2454	2	Rat	8.2	pKd	=	8.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	472	3	0	7	2.4	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nccnc5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44447078	101392	0	None	-2	7	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	534	2	1	6	3.8	CN1C[C@@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	CHEMBL252232	101392	0	None	-2	7	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human recombinant sst1 receptorBinding affinity to human recombinant sst1 receptor	ChEMBL	534	2	1	6	3.8	CN1C[C@@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@H]2c3cccc4[nH]c(Br)c(c34)C[C@@H]21	10.1016/j.bmcl.2007.12.030
	44441868	161619	0	None	478	2	Rat	7.3	pKd	=	7.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	421	3	0	6	1.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccnn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL400481	161619	0	None	478	2	Rat	7.3	pKd	=	7.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	421	3	0	6	1.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccnn4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46880577	12316	0	None	-3	2	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@H]21	10.1016/j.bmcl.2010.01.063
	CHEMBL1076654	12316	0	None	-3	2	Human	6.3	pKd	=	6.3	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.7	CC(Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C[C@@H]2CCCC[C@H]21	10.1016/j.bmcl.2010.01.063
	44441872	101046	0	None	18	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	568	5	0	8	2.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ncccc4OS(=O)(=O)C(F)(F)F)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250314	101046	0	None	18	2	Rat	6.3	pKd	=	6.3	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	568	5	0	8	2.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ncccc4OS(=O)(=O)C(F)(F)F)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	9871544	20988	3	None	-120	11	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076624	20988	3	None	-120	11	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1198948	20988	3	None	-120	11	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)[C@H]3CCCC[C@H]3C2)cn1	10.1016/j.bmcl.2010.01.063
	44441914	160682	0	None	15	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	498	4	1	6	1.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(S(N)(=O)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL398319	160682	0	None	15	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	498	4	1	6	1.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(S(N)(=O)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441668	101307	0	None	1202	2	Rat	8.2	pKd	=	8.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	476	4	0	6	3.2	CC(=O)c1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL251752	101307	0	None	1202	2	Rat	8.2	pKd	=	8.2	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	476	4	0	6	3.2	CC(=O)c1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44565066	19406	0	None	-	1	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	471	7	0	6	3.0	CN(CCC(=O)N1CCN(c2ccc(=O)n(C)n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187128	19406	0	None	-	1	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	471	7	0	6	3.0	CN(CCC(=O)N1CCN(c2ccc(=O)n(C)n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL491145	19406	0	None	-	1	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	471	7	0	6	3.0	CN(CCC(=O)N1CCN(c2ccc(=O)n(C)n2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44565008	19439	0	None	-	1	Rat	7.2	pKd	=	7.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL1187261	19439	0	None	-	1	Rat	7.2	pKd	=	7.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL495264	19439	0	None	-	1	Rat	7.2	pKd	=	7.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	507	7	0	3	5.9	CN(CCC(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL413830	219868	0	None	-23	5	Human	6.2	pKd	=	6.2	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)N(C)[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm000361p
	46880579	12318	0	None	-5	2	Human	5.2	pKd	=	5.2	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.6	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H]2CCCC[C@H]2[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076656	12318	0	None	-5	2	Human	5.2	pKd	=	5.2	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.6	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H]2CCCC[C@H]2[C@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	CHEMBL409019	219521	0	None	-21	5	Human	6.2	pKd	=	6.2	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1C)C(N)=O	10.1021/jm000361p
	44441913	101019	0	None	13	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	497	4	0	6	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(S(C)(=O)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250098	101019	0	None	13	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	497	4	0	6	2.5	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(S(C)(=O)=O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441905	101125	0	None	38	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	435	3	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250704	101125	0	None	38	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	435	3	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL386676	219165	0	None	-16	4	Human	6.2	pKd	=	6.2	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N(C)[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	44441878	101130	0	None	7	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	484	3	0	5	3.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc(C)nc5ccccc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250723	101130	0	None	7	2	Rat	6.2	pKd	=	6.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	484	3	0	5	3.9	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cc(C)nc5ccccc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564856	186451	0	None	575	2	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	510	10	0	5	5.3	C=CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	CHEMBL474345	186451	0	None	575	2	Rat	8.2	pKd	=	8.2	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	510	10	0	5	5.3	C=CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2009.01.072
	44441875	175911	0	None	1513	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	450	3	0	6	1.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(=O)n4C)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL440235	175911	0	None	1513	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	450	3	0	6	1.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(=O)n4C)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44564783	183704	0	None	-10	4	Human	8.1	pKd	=	8.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	484	8	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2010.01.063
	CHEMBL461988	183704	0	None	-10	4	Human	8.1	pKd	=	8.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	484	8	0	5	4.8	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21	10.1016/j.bmcl.2010.01.063
	44441874	161067	0	None	1548	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	436	3	1	5	1.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(=O)[nH]4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL398655	161067	0	None	1548	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	436	3	1	5	1.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc(=O)[nH]4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441676	100791	0	None	1258	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	510	5	0	7	3.7	COc1ccc(SC)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	CHEMBL248717	100791	0	None	1258	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membraneDisplacement of [125I]SRIF14 from sst1 receptor in rat brain cortex membrane	ChEMBL	510	5	0	7	3.7	COc1ccc(SC)c2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.086
	44441930	101235	0	None	87	2	Rat	7.2	pKd	=	7.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	429	2	1	3	3.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCc4c([nH]c5ccccc45)C3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251300	101235	0	None	87	2	Rat	7.2	pKd	=	7.2	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	429	2	1	3	3.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCc4c([nH]c5ccccc45)C3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL2370168	216586	0	None	-1548	5	Human	5.2	pKd	=	5.2	Binding	In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.In vitro inhibition of radioligand binding to human somatostatin receptor (hsst1) expressed in hSF6 cells.	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCNC(=O)[C@@H](N)Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)CN(Cc2ccccc2)C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm970393l
	46880588	20989	0	None	1	7	Human	6.1	pKd	=	6.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076625	20989	0	None	1	7	Human	6.1	pKd	=	6.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1198974	20989	0	None	1	7	Human	6.1	pKd	=	6.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL408752	219509	0	None	-5011	4	Human	6.1	pKd	=	6.1	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	44564857	185717	0	None	-1	4	Human	7.1	pKd	=	7.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	524	10	0	5	5.5	O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2010.01.063
	CHEMBL470331	185717	0	None	-1	4	Human	7.1	pKd	=	7.1	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	524	10	0	5	5.5	O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1	10.1016/j.bmcl.2010.01.063
	44564785	183721	0	None	112	2	Rat	7.1	pKd	=	7.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	446	8	0	5	4.0	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCc1cccc2ccccc12	10.1016/j.bmcl.2009.01.072
	CHEMBL462158	183721	0	None	112	2	Rat	7.1	pKd	=	7.1	Binding	Binding affinity to rat sst1 receptorBinding affinity to rat sst1 receptor	ChEMBL	446	8	0	5	4.0	CN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCc1cccc2ccccc12	10.1016/j.bmcl.2009.01.072
	44441898	100999	0	None	1230	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	444	3	0	5	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C#N)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249932	100999	0	None	1230	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	444	3	0	5	3.0	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C#N)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441877	101080	0	None	602	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	494	3	0	5	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5ccc(C#N)cc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250522	101080	0	None	602	2	Rat	8.1	pKd	=	8.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	494	3	0	5	4.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5ccc(C#N)cc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441924	101164	0	None	30	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	450	3	0	3	4.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ccc(Cl)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250912	101164	0	None	30	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	450	3	0	3	4.7	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CC=C(c4ccc(Cl)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL413373	219841	0	None	-269	4	Human	6.1	pKd	=	6.1	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		CN[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm000361p
	46880588	20989	0	None	-1	7	Rat	6.1	pKd	=	6.1	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076625	20989	0	None	-1	7	Rat	6.1	pKd	=	6.1	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	CHEMBL1198974	20989	0	None	-1	7	Rat	6.1	pKd	=	6.1	Binding	Displacement of [125I]SRIF-14 from rat cortex membrane SST1 receptorDisplacement of [125I]SRIF-14 from rat cortex membrane SST1 receptor	ChEMBL	526	7	0	5	4.6	COc1ccc(C[C@@H](C)CN2C[C@H]3CCCC[C@H]3[C@@H](C(=O)N3CCN(c4ccc(F)c(F)c4)CC3)C2)cn1	10.1016/j.bmcl.2010.01.063
	44441912	21488	0	None	-	1	Rat	4.1	pKd	=	4.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	463	4	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(=O)O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL1206217	21488	0	None	-	1	Rat	4.1	pKd	=	4.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	463	4	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(=O)O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL249894	21488	0	None	-	1	Rat	4.1	pKd	=	4.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	463	4	1	5	2.8	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc(C(=O)O)cc4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL405561	219345	0	None	-316	4	Human	6.1	pKd	=	6.1	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](N(C)C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL412466	219771	0	None	-467	4	Human	6.1	pKd	=	6.1	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N(C)[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	44441876	101079	0	None	63	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	469	3	0	4	4.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5ccccc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL250521	101079	0	None	63	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	469	3	0	4	4.2	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4cccc5ccccc45)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	44441887	101204	0	None	239	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	460	3	0	7	2.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nccn5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	CHEMBL251121	101204	0	None	239	2	Rat	7.1	pKd	=	7.1	Binding	Displacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membraneDisplacement of [125I]SRIF14 from rat sst1 receptor from rat brain cortex membrane	ChEMBL	460	3	0	7	2.1	COc1cccc2c1C[C@H]1C[C@@H](C(=O)N3CCN(c4ccc5nccn5n4)CC3)CN(C)[C@@H]1C2	10.1016/j.bmcl.2007.04.078
	46880578	12317	0	None	-83	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.6	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H]2CCCC[C@H]2[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076655	12317	0	None	-83	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	548	7	0	7	4.6	CC(Cc1ccc2c(c1)OCO2)CN1C[C@H]2CCCC[C@H]2[C@@H](C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C1	10.1016/j.bmcl.2010.01.063
	46880852	12336	0	None	-107	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	539	6	0	5	5.0	C[C@@H](Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076717	12336	0	None	-107	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	539	6	0	5	5.0	C[C@@H](Cc1ccc2c(c1)OCO2)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	46880854	12338	0	None	-263	2	Human	5.0	pKd	=	5.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	536	6	0	6	4.3	C[C@@H](Cc1ccc2ncnn2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076719	12338	0	None	-263	2	Human	5.0	pKd	=	5.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	536	6	0	6	4.3	C[C@@H](Cc1ccc2ncnn2c1)CN1C[C@@H](C(=O)N2CCN(c3ccc(F)c(F)c3)CC2)[C@H]2CCCC[C@H]2C1	10.1016/j.bmcl.2010.01.063
	46880584	12310	0	None	-758	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL1076621	12310	0	None	-758	2	Human	6.0	pKd	=	6.0	Binding	Binding affinity to human SST1 receptorBinding affinity to human SST1 receptor	ChEMBL	620	9	0	9	4.4	COC(=O)c1cc(C[C@H](C)CN2C[C@@H](C(=O)N3CCN(c4ccc([N+](=O)[O-])cc4)CC3)[C@H]3CCCC[C@H]3C2)cc(C(=O)OC)c1	10.1016/j.bmcl.2010.01.063
	CHEMBL411017	219637	0	None	-67	4	Human	6.0	pKd	=	6.0	Binding	Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)Binding affinity was determined on cloned human somatostatin receptor-1 (hsst1)	ChEMBL		None	None	None		C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N(C)[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O	10.1021/jm000361p
	CHEMBL3349516	218196	0	None	-1	4	Human	9.8	pKi	=	9.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349522	218201	0	None	-1	4	Human	9.7	pKi	=	9.7	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349521	218200	0	None	-1	4	Human	9.6	pKi	=	9.6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	16129706	215810	40	None	-6	5	Human	9.5	pKi	=	9.5	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0108449
	CHEMBL1823872	215810	40	None	-6	5	Human	9.5	pKi	=	9.5	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm0108449
	CHEMBL3098601	217797	0	None	-1	5	Human	9.5	pKi	=	9.5	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1C/C=C\C[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmcl.2013.11.065
	CHEMBL1823873	215811	9	None	1	4	Human	9.5	pKi	=	9.5	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmcl.2013.11.065
	16129706	215810	40	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/s0960-894x(01)00107-x
	CHEMBL1823872	215810	40	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/s0960-894x(01)00107-x
	16129706	215810	40	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm020424z
	CHEMBL1823872	215810	40	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm020424z
	CHEMBL408362	219489	0	None	-9	5	Human	9.4	pKi	=	9.4	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm980194h
	16129706	215810	40	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmcl.2013.11.065
	CHEMBL1823872	215810	40	None	-6	5	Human	9.4	pKi	=	9.4	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1016/j.bmcl.2013.11.065
	CHEMBL3349517	218197	0	None	-1	4	Human	9.3	pKi	=	9.3	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	16129706	215810	40	None	-6	5	Human	9.2	pKi	=	9.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL1823872	215810	40	None	-6	5	Human	9.2	pKi	=	9.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349518	218198	0	None	10	4	Human	9.2	pKi	=	9.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349513	218193	0	None	-1	4	Human	9.1	pKi	=	9.1	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC1=O	10.1021/jm021093t
	CHEMBL3349605	218213	0	None	-6	4	Human	8.8	pKi	=	8.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H]2C[C@@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	CHEMBL3349606	218214	0	None	-15	4	Human	8.8	pKi	=	8.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		CN(C)CCNC(=O)O[C@@H]1C[C@H]2C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc3ccc(OCc4ccccc4)cc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N2C1	10.1021/jm021093t
	44308969	211143	0	None	1096	5	Human	8.8	pKi	=	8.8	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NC[C@@H]1CCC[C@H](CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	CHEMBL71723	211143	0	None	1096	5	Human	8.8	pKi	=	8.8	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NC[C@@H]1CCC[C@H](CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	CHEMBL442494	220692	0	None	-6	5	Human	8.7	pKi	=	8.7	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm0005048
	CHEMBL3349603	218211	0	None	-15	5	Human	8.0	pKi	=	8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCCCNC(=O)O[C@@H]1C[C@H]2C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc3ccc(OCc4ccccc4)cc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N2C1	10.1021/jm021093t
	91809310	132563	0	None	-43	4	Human	8.0	pKi	=	8.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1618	27	19	17	3.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647709	132563	0	None	-43	4	Human	8.0	pKi	=	8.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1618	27	19	17	3.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	91809283	132538	0	None	-1258	6	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1456	23	17	16	2.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647684	132538	0	None	-1258	6	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1456	23	17	16	2.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL2311098	216284	0	None	-83	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369733	216440	0	None	-5	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N(C)[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369734	216441	0	None	-14	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)N(C)C1=O	10.1021/jm0005048
	CHEMBL2369735	216442	0	None	-181	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369750	216447	0	None	-27	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		CN[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@H]1CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)[C@@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC1=O	10.1021/jm0005048
	CHEMBL2369751	216448	0	None	-11	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		CNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H]1CSSC[C@H](N(C)C(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@H]([C@H](C)O)C(=O)N1	10.1021/jm0005048
	CHEMBL2369752	216449	0	None	-19	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)N(C)C(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369754	216451	0	None	-107	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)N(C)C(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369755	216452	0	None	-165	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369756	216453	0	None	-5	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)N(C)C(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369757	216454	0	None	-40	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2cccnc2)CSSC[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369758	216455	0	None	-36	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369759	216456	0	None	1	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)C(N)CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369760	216457	0	None	-42	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@@H](N)CCNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL2369761	216458	0	None	-8	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		CNC(=O)[C@@H](NC(=O)[C@@H]1CSSC[C@@H](N(C)C(=O)C(N)Cc2ccc(Cl)cc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@H]([C@H](C)O)C(=O)N1)C(c1ccccc1)c1ccccc1	10.1021/jm0005048
	CHEMBL2371893	216926	0	None	-89	5	Human	6.0	pKi	=	6	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)N(C)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(C(F)(F)F)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	CHEMBL3349515	218195	0	None	-12	4	Human	6.0	pKi	=	6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349525	218203	0	None	-10	4	Human	6.0	pKi	=	6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	142471769	198564	0	None	-301	2	Human	6.0	pKi	=	6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	456	10	2	6	4.3	COc1ccc(Cc2nnc(Cc3c[nH]c4ccc(OC)cc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5198142	198564	0	None	-301	2	Human	6.0	pKi	=	6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	456	10	2	6	4.3	COc1ccc(Cc2nnc(Cc3c[nH]c4ccc(OC)cc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	44387399	175796	0	None	-2	3	Human	6.0	pKi	=	6.0	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL	1055	13	11	14	1.3	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@H](NN2Cc3ccccc3CC2C(=O)O)CSSC[C@@H](C(=O)NN2Cc3ccccc3CC2C(=O)O)NC1=O	10.1021/jm9806289
	CHEMBL439350	175796	0	None	-2	3	Human	6.0	pKi	=	6.0	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL	1055	13	11	14	1.3	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@H](NN2Cc3ccccc3CC2C(=O)O)CSSC[C@@H](C(=O)NN2Cc3ccccc3CC2C(=O)O)NC1=O	10.1021/jm9806289
	CHEMBL385746	219143	0	None	-72	4	Human	6.0	pKi	=	6.0	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471841	198364	0	None	-363	3	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1ccc2[nH]cc(Cc3nnc(Cc4ccc(F)cc4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	CHEMBL5195145	198364	0	None	-363	3	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1ccc2[nH]cc(Cc3nnc(Cc4ccc(F)cc4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	91809284	132539	0	None	-512	6	Human	7.0	pKi	=	7.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1896	34	20	20	5.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647685	132539	0	None	-512	6	Human	7.0	pKi	=	7.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1896	34	20	20	5.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL385689	219138	0	None	-15	4	Human	6.0	pKi	=	6.0	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc(F)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	142471716	198271	0	None	-208	3	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1ccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5193686	198271	0	None	-208	3	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1ccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	142471929	197946	0	None	-676	2	Human	5.9	pKi	=	5.9	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	414	8	2	4	4.4	Fc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5188841	197946	0	None	-676	2	Human	5.9	pKi	=	5.9	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	414	8	2	4	4.4	Fc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL414116	219890	0	None	-5	4	Human	5.9	pKi	=	5.9	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	90665463	116039	0	None	-4	5	Human	4.9	pKi	=	4.9	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	882	28	3	9	4.5	COC(=O)CCN(Cc1ccccc1)C(=O)CCN(C[C@@H](C)O)C(=O)CCN(CCCCN)C(=O)CCN(CCc1c[nH]c2ccccc12)C(=O)CCN(Cc1ccccc1)C(C)=O	10.1039/C2MD20265D
	CHEMBL3218124	116039	0	None	-4	5	Human	4.9	pKi	=	4.9	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	882	28	3	9	4.5	COC(=O)CCN(Cc1ccccc1)C(=O)CCN(C[C@@H](C)O)C(=O)CCN(CCCCN)C(=O)CCN(CCc1c[nH]c2ccccc12)C(=O)CCN(Cc1ccccc1)C(C)=O	10.1039/C2MD20265D
	168288485	198510	0	None	-2454	4	Human	5.9	pKi	=	5.9	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	430	8	2	4	5.0	Clc1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5197201	198510	0	None	-2454	4	Human	5.9	pKi	=	5.9	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	430	8	2	4	5.0	Clc1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL3349514	218194	0	None	-6	4	Human	6.9	pKi	=	6.9	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	44397706	73965	0	None	-70	5	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	456	9	2	6	5.4	Cc1cccc2c(CCSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12	10.1016/j.bmcl.2005.05.061
	CHEMBL187768	73965	0	None	-70	5	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	456	9	2	6	5.4	Cc1cccc2c(CCSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12	10.1016/j.bmcl.2005.05.061
	CHEMBL2369749	216446	0	None	-114	5	Human	5.9	pKi	=	5.9	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm0005048
	10296743	68612	0	None	-	1	Human	5.9	pKi	=	5.9	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	436	7	3	3	5.8	O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)OCc1ccccc1	10.1016/s0960-894x(01)00107-x
	CHEMBL177337	68612	0	None	-	1	Human	5.9	pKi	=	5.9	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	436	7	3	3	5.8	O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)OCc1ccccc1	10.1016/s0960-894x(01)00107-x
	CHEMBL408347	219486	0	None	-117	4	Human	5.9	pKi	=	5.9	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471978	199222	0	None	-891	2	Human	5.8	pKi	=	5.8	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	396	8	2	4	4.3	c1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5208396	199222	0	None	-891	2	Human	5.8	pKi	=	5.8	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	396	8	2	4	4.3	c1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	44385652	67166	0	None	-6	5	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	405	6	4	2	5.5	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccccc1	10.1016/s0960-894x(01)00107-x
	CHEMBL174872	67166	0	None	-6	5	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	405	6	4	2	5.5	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccccc1	10.1016/s0960-894x(01)00107-x
	10210016	67209	0	None	-7	3	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	441	6	4	2	5.7	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(F)cc1F	10.1016/s0960-894x(01)00107-x
	CHEMBL175197	67209	0	None	-7	3	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	441	6	4	2	5.7	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(F)cc1F	10.1016/s0960-894x(01)00107-x
	2054	10746	15	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	71306	10746	15	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	CHEMBL264186	10746	15	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	CHEMBL3349523	10746	15	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	DB04894	10746	15	None	-741	11	Human	6.8	pKi	=	6.8	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	91809287	167037	0	None	-3162	6	Human	6.8	pKi	=	6.8	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1472	23	17	16	1.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S@+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL4110066	167037	0	None	-3162	6	Human	6.8	pKi	=	6.8	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1472	23	17	16	1.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S@+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	90665462	116007	0	None	-5	4	Human	4.8	pKi	=	4.8	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	867	27	3	9	4.1	COC(=O)CCN(Cc1ccccc1)C(=O)CCN(C[C@@H](C)O)C(=O)CCN(CCCCN)C(=O)CN(CCc1c[nH]c2ccccc12)C(=O)CCN(Cc1ccccc1)C(C)=O	10.1039/C2MD20265D
	CHEMBL3217760	116007	0	None	-5	4	Human	4.8	pKi	=	4.8	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	867	27	3	9	4.1	COC(=O)CCN(Cc1ccccc1)C(=O)CCN(C[C@@H](C)O)C(=O)CCN(CCCCN)C(=O)CN(CCc1c[nH]c2ccccc12)C(=O)CCN(Cc1ccccc1)C(C)=O	10.1039/C2MD20265D
	90665460	116037	0	None	-7	5	Human	4.8	pKi	=	4.8	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	793	13	3	7	3.9	C[C@@H](O)CN1CCC(=O)N(Cc2ccccc2)CCC(=O)N(Cc2ccccc2)CCC(=O)N(CCc2c[nH]c3ccccc23)CC(=O)N(CCCCN)CCC1=O	10.1039/C2MD20265D
	CHEMBL3218122	116037	0	None	-7	5	Human	4.8	pKi	=	4.8	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	793	13	3	7	3.9	C[C@@H](O)CN1CCC(=O)N(Cc2ccccc2)CCC(=O)N(Cc2ccccc2)CCC(=O)N(CCc2c[nH]c3ccccc23)CC(=O)N(CCCCN)CCC1=O	10.1039/C2MD20265D
	CHEMBL385745	219142	0	None	-15	4	Human	5.8	pKi	=	5.8	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471655	197204	0	None	-562	3	Human	5.8	pKi	=	5.8	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	426	9	2	5	4.3	COc1ccc2[nH]cc(Cc3nnc(Cc4ccccc4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	CHEMBL5178013	197204	0	None	-562	3	Human	5.8	pKi	=	5.8	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	426	9	2	5	4.3	COc1ccc2[nH]cc(Cc3nnc(Cc4ccccc4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	10166743	130724	0	None	-21	5	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	439	6	4	2	6.1	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(Cl)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL362859	130724	0	None	-21	5	Human	5.8	pKi	=	5.8	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	439	6	4	2	6.1	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(Cl)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL275806	217602	0	None	-1	4	Human	6.8	pKi	=	6.8	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)O)NC1=O	10.1021/jm9806289
	11848679	96019	0	None	-134	6	Human	5.8	pKi	=	5.8	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	489	9	3	9	2.9	CCOc1cc(CN2CCC(Nc3nc4cc(S(N)(=O)=O)ccc4o3)CC2)cc(OCC)c1N	10.1016/j.bmcl.2009.09.024
	CHEMBL236788	96019	0	None	-134	6	Human	5.8	pKi	=	5.8	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	489	9	3	9	2.9	CCOc1cc(CN2CCC(Nc3nc4cc(S(N)(=O)=O)ccc4o3)CC2)cc(OCC)c1N	10.1016/j.bmcl.2009.09.024
	44397648	73538	0	None	-44	5	Human	6.8	pKi	=	6.8	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	476	9	2	6	5.7	NCCCCn1c(SCCc2c[nH]c3c(Cl)cccc23)nnc1-c1ccc2ccccc2n1	10.1016/j.bmcl.2005.05.061
	CHEMBL185861	73538	0	None	-44	5	Human	6.8	pKi	=	6.8	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	476	9	2	6	5.7	NCCCCn1c(SCCc2c[nH]c3c(Cl)cccc23)nnc1-c1ccc2ccccc2n1	10.1016/j.bmcl.2005.05.061
	44332931	11397	0	None	-1047	2	Human	5.8	pKi	=	5.8	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	396	3	3	2	6.1	c1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCCCC4)N3)n2)cc1	10.1021/jm0108449
	CHEMBL102892	11397	0	None	-1047	2	Human	5.8	pKi	=	5.8	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	396	3	3	2	6.1	c1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCCCC4)N3)n2)cc1	10.1021/jm0108449
	CHEMBL1201959	11397	0	None	-1047	2	Human	5.8	pKi	=	5.8	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	396	3	3	2	6.1	c1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCCCC4)N3)n2)cc1	10.1021/jm0108449
	142471665	198486	0	None	-602	2	Human	5.7	pKi	=	5.7	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	414	8	2	4	4.4	Fc1ccc2c(Cc3nnc(Cc4ccccc4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5196971	198486	0	None	-602	2	Human	5.7	pKi	=	5.7	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	414	8	2	4	4.4	Fc1ccc2c(Cc3nnc(Cc4ccccc4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL438281	220542	0	None	1	4	Human	6.7	pKi	=	6.7	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccccc2F)CSSC[C@H](C(=O)N[C@@H](Cc2ccccc2F)C(N)=O)NC1=O	10.1021/jm9806289
	44385757	68110	0	None	-1	4	Human	5.7	pKi	=	5.7	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	461	6	4	2	6.8	CC(C)(C)c1ccc(C(=N)N[C@H](Cc2c[nH]c3ccccc23)c2nc(-c3ccccc3)c[nH]2)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL176730	68110	0	None	-1	4	Human	5.7	pKi	=	5.7	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	461	6	4	2	6.8	CC(C)(C)c1ccc(C(=N)N[C@H](Cc2c[nH]c3ccccc23)c2nc(-c3ccccc3)c[nH]2)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL3349520	218199	0	None	1	4	Human	7.7	pKi	=	7.7	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL407496	219444	0	None	-63	5	Human	5.7	pKi	=	5.7	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(F)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc(F)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	CHEMBL1794035	215716	0	None	-7	5	Human	8.7	pKi	=	8.7	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]([C@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O	10.1021/jm0005048
	16129706	215810	40	None	-6	5	Human	8.6	pKi	=	8.6	Binding	Binding affinity towards somatostatin receptor type 1Binding affinity towards somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm050376t
	CHEMBL1823872	215810	40	None	-6	5	Human	8.6	pKi	=	8.6	Binding	Binding affinity towards somatostatin receptor type 1Binding affinity towards somatostatin receptor type 1	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm050376t
	10580397	106091	0	None	-4	5	Human	5.7	pKi	=	5.7	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	677	20	3	7	6.9	NCCCCCNC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL282129	106091	0	None	-4	5	Human	5.7	pKi	=	5.7	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	677	20	3	7	6.9	NCCCCCNC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1	10.1021/jm9800346
	142471719	197281	0	None	-204	2	Human	5.7	pKi	=	5.7	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	1	5	5.5	Cn1cc(CCc2nnc(Cc3cccc(C(F)(F)F)c3)n2CCCc2c[nH]cn2)c2ccccc21	10.1039/D1MD00044F
	CHEMBL5179321	197281	0	None	-204	2	Human	5.7	pKi	=	5.7	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	1	5	5.5	Cn1cc(CCc2nnc(Cc3cccc(C(F)(F)F)c3)n2CCCc2c[nH]cn2)c2ccccc21	10.1039/D1MD00044F
	13690207	122160	0	None	-812	5	Human	6.7	pKi	=	6.7	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1039/C2MD20265D
	CHEMBL3350037	122160	0	None	-812	5	Human	6.7	pKi	=	6.7	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1039/C2MD20265D
	10094509	137464	0	None	-63	5	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	435	7	4	3	5.5	COc1ccc(C(=N)N[C@H](Cc2c[nH]c3ccccc23)c2nc(-c3ccccc3)c[nH]2)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL368334	137464	0	None	-63	5	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	435	7	4	3	5.5	COc1ccc(C(=N)N[C@H](Cc2c[nH]c3ccccc23)c2nc(-c3ccccc3)c[nH]2)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL429166	220288	0	None	-2	4	Human	6.6	pKi	=	6.6	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)(C)C[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	15965425	8987	7	None	-239883	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity to human somatostatin receptor type 1Binding affinity to human somatostatin receptor type 1	ChEMBL	645	11	5	7	4.3	NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)[C@@H]([C@H](c1c[nH]c2c1cccc2)C)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2	10.1021/acs.jmedchem.6b01029
	2046	8987	7	None	-239883	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity to human somatostatin receptor type 1Binding affinity to human somatostatin receptor type 1	ChEMBL	645	11	5	7	4.3	NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)[C@@H]([C@H](c1c[nH]c2c1cccc2)C)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2	10.1021/acs.jmedchem.6b01029
	CHEMBL99895	8987	7	None	-239883	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity to human somatostatin receptor type 1Binding affinity to human somatostatin receptor type 1	ChEMBL	645	11	5	7	4.3	NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)[C@@H]([C@H](c1c[nH]c2c1cccc2)C)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2	10.1021/acs.jmedchem.6b01029
	15965425	8987	7	None	-239883	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL	645	11	5	7	4.3	NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)[C@@H]([C@H](c1c[nH]c2c1cccc2)C)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2	10.1021/jm020424z
	2046	8987	7	None	-239883	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL	645	11	5	7	4.3	NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)[C@@H]([C@H](c1c[nH]c2c1cccc2)C)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2	10.1021/jm020424z
	CHEMBL99895	8987	7	None	-239883	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards Somatostatin receptor type 1 (hsst1)Binding affinity towards Somatostatin receptor type 1 (hsst1)	ChEMBL	645	11	5	7	4.3	NCCCC[C@@H](C(=O)OC(C)(C)C)NC(=O)[C@@H]([C@H](c1c[nH]c2c1cccc2)C)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2	10.1021/jm020424z
	91809303	132556	0	None	-75	6	Human	7.6	pKi	=	7.6	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1659	28	18	16	3.8	CC(=O)N(CCC(=O)N[C@@H](CN[C@@H]1CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC1=O)Cc1ccc(O)cc1)C[C@@H]1C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1	nan
	CHEMBL3647702	132556	0	None	-75	6	Human	7.6	pKi	=	7.6	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1659	28	18	16	3.8	CC(=O)N(CCC(=O)N[C@@H](CN[C@@H]1CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC1=O)Cc1ccc(O)cc1)C[C@@H]1C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1	nan
	10325243	107271	0	None	-1	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	549	17	1	7	5.3	CO[C@@H]1O[C@H](COCCCCCN)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL29102	107271	0	None	-1	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	549	17	1	7	5.3	CO[C@@H]1O[C@H](COCCCCCN)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	44309052	210726	0	None	-123	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NC[C@H]1CCC[C@@H](CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	CHEMBL69303	210726	0	None	-123	5	Human	5.6	pKi	=	5.6	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NC[C@H]1CCC[C@@H](CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	13690207	122160	0	None	-812	5	Human	6.6	pKi	=	6.6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1021/jm021093t
	CHEMBL3350037	122160	0	None	-812	5	Human	6.6	pKi	=	6.6	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1021/jm021093t
	44385504	67822	0	None	-6	5	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	489	7	4	3	6.4	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(OC(F)(F)F)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL176313	67822	0	None	-6	5	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	489	7	4	3	6.4	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(OC(F)(F)F)cc1	10.1016/s0960-894x(01)00107-x
	142471684	198231	0	None	-1174	2	Human	5.6	pKi	=	5.6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	426	9	2	5	4.3	COc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5193172	198231	0	None	-1174	2	Human	5.6	pKi	=	5.6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	426	9	2	5	4.3	COc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	91809306	132559	0	None	-190	4	Human	7.6	pKi	=	7.6	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1738	28	16	17	6.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N(CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647705	132559	0	None	-190	4	Human	7.6	pKi	=	7.6	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1738	28	16	17	6.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N(CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	10411795	137397	0	None	-15	3	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	457	6	4	2	5.9	O=C(Nc1ccc(F)cc1F)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	CHEMBL368176	137397	0	None	-15	3	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	457	6	4	2	5.9	O=C(Nc1ccc(F)cc1F)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	142471848	198046	0	None	-263	4	Human	6.6	pKi	=	6.6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	8	2	4	5.2	Fc1ccc2c(Cc3nnc(Cc4cccc(Br)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5190457	198046	0	None	-263	4	Human	6.6	pKi	=	6.6	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	8	2	4	5.2	Fc1ccc2c(Cc3nnc(Cc4cccc(Br)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	44385712	67118	0	None	-4	4	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	343	5	4	2	4.4	CC(=N)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	CHEMBL174490	67118	0	None	-4	4	Human	5.6	pKi	=	5.6	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	343	5	4	2	4.4	CC(=N)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	91809320	133156	0	None	-50	3	Human	7.5	pKi	=	7.5	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1897	34	19	18	6.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3650456	133156	0	None	-50	3	Human	7.5	pKi	=	7.5	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1897	34	19	18	6.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	44377555	64305	0	None	-4	5	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	384	5	1	5	5.2	NCCCc1nc(-c2csc3ccccc23)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL166247	64305	0	None	-4	5	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	384	5	1	5	5.2	NCCCc1nc(-c2csc3ccccc23)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL3349601	218209	0	None	-5	4	Human	8.4	pKi	=	8.4	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H]2C[C@@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	CHEMBL3349602	218210	0	None	-10	5	Human	8.4	pKi	=	8.4	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2C[C@@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	10009650	106571	0	None	-3	4	Human	6.5	pKi	=	6.5	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	668	20	3	8	6.1	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2c[nH]cn2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL285333	106571	0	None	-3	4	Human	6.5	pKi	=	6.5	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	668	20	3	8	6.1	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2c[nH]cn2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	13690207	122160	0	None	-812	5	Human	6.5	pKi	=	6.5	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1016/j.bmcl.2013.11.065
	CHEMBL3350037	122160	0	None	-812	5	Human	6.5	pKi	=	6.5	Binding	Displacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cellsDisplacement of [125I]-somatostatin from human SSTR1 expressed in CHO-K1 cells	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1016/j.bmcl.2013.11.065
	142471737	197083	0	None	-77	3	Human	5.5	pKi	=	5.5	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	1	5	5.8	Cn1cc(CCc2nnc(Cc3ccc(Cl)c(Cl)c3)n2CCCc2c[nH]cn2)c2ccccc21	10.1039/D1MD00044F
	CHEMBL5176020	197083	0	None	-77	3	Human	5.5	pKi	=	5.5	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	1	5	5.8	Cn1cc(CCc2nnc(Cc3ccc(Cl)c(Cl)c3)n2CCCc2c[nH]cn2)c2ccccc21	10.1039/D1MD00044F
	91809277	132532	0	None	-107	6	Human	7.5	pKi	=	7.5	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1457	23	16	14	3.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647678	132532	0	None	-107	6	Human	7.5	pKi	=	7.5	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1457	23	16	14	3.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	71461645	85679	0	None	-4	4	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	367	5	2	4	4.4	NCCCc1nc(-c2c[nH]c3ccccc23)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL2112935	85679	0	None	-4	4	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	367	5	2	4	4.4	NCCCc1nc(-c2c[nH]c3ccccc23)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL438726	220568	0	None	2	4	Human	7.5	pKi	=	7.5	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccccn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(F)c(F)c(F)c(F)c2F)CSSC[C@H](C(=O)N[C@@H](Cc2c(F)c(F)c(F)c(F)c2F)C(N)=O)NC1=O	10.1021/jm9806289
	10248767	63966	0	None	-7	4	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	373	6	1	6	3.9	NCCCc1nc(-c2cccc([N+](=O)[O-])c2)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	CHEMBL164964	63966	0	None	-7	4	Human	5.5	pKi	=	5.5	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	373	6	1	6	3.9	NCCCc1nc(-c2cccc([N+](=O)[O-])c2)cn2cc(-c3ccccc3)nc12	10.1016/s0960-894x(01)00051-8
	44386389	136861	0	None	-6	5	Human	5.5	pKi	=	5.5	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	473	6	4	2	6.5	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(C(F)(F)F)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL367699	136861	0	None	-6	5	Human	5.5	pKi	=	5.5	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	473	6	4	2	6.5	N=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1)c1ccc(C(F)(F)F)cc1	10.1016/s0960-894x(01)00107-x
	CHEMBL414386	219908	0	None	-4	4	Human	6.5	pKi	=	6.5	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471801	199078	0	None	-199	4	Human	6.4	pKi	=	6.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	494	9	2	5	5.3	COc1ccc2[nH]cc(Cc3nnc(Cc4cccc(C(F)(F)F)c4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	CHEMBL5206148	199078	0	None	-199	4	Human	6.4	pKi	=	6.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	494	9	2	5	5.3	COc1ccc2[nH]cc(Cc3nnc(Cc4cccc(C(F)(F)F)c4)n3CCCc3c[nH]cn3)c2c1	10.1039/D1MD00044F
	142471923	198690	0	None	-512	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	488	10	2	6	3.9	CS(=O)(=O)c1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5200112	198690	0	None	-512	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	488	10	2	6	3.9	CS(=O)(=O)c1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL406491	219390	0	None	4	4	Human	7.4	pKi	=	7.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccccc2F)CSSC[C@@H](C(=O)N[C@@H](Cc2ccccc2F)C(N)=O)NC1=O	10.1021/jm9806289
	2070	7484	5	None	-5888	4	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	426	8	3	2	7.0	CCCCC1(CCCC)N[C@H](Cc2c1[nH]c1c2cccc1)c1ncc([nH]1)c1ccccc1	10.1021/jm0108449
	9802572	7484	5	None	-5888	4	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	426	8	3	2	7.0	CCCCC1(CCCC)N[C@H](Cc2c1[nH]c1c2cccc1)c1ncc([nH]1)c1ccccc1	10.1021/jm0108449
	CHEMBL2069499	7484	5	None	-5888	4	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	426	8	3	2	7.0	CCCCC1(CCCC)N[C@H](Cc2c1[nH]c1c2cccc1)c1ncc([nH]1)c1ccccc1	10.1021/jm0108449
	CHEMBL437448	220498	0	None	-23	5	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Br)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc(Br)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	91809275	132530	0	None	-316	6	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1603	27	18	17	3.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647676	132530	0	None	-316	6	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1603	27	18	17	3.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL2369753	216450	0	None	-4	5	Human	6.4	pKi	=	6.4	Binding	Ability to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cellsAbility to displace [125 I]labelled Tyr11-somatostatin from human hsst-1 receptor expressed on CHO cells	ChEMBL		None	None	None		C[C@H](O)[C@@H]1C(=O)N[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)CSSC[C@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)C(=O)N[C@@H](Cc2cccnc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N1C	10.1021/jm0005048
	9852911	106159	0	None	-26	6	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL282618	106159	0	None	-26	6	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1	10.1021/jm9800346
	10770814	107569	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL29311	107569	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	44377591	62407	0	None	-1	4	Human	5.4	pKi	=	5.4	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	536	9	3	6	5.6	CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(-c3csc4ccccc34)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	CHEMBL162140	62407	0	None	-1	4	Human	5.4	pKi	=	5.4	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	536	9	3	6	5.6	CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(-c3csc4ccccc34)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	142471961	198200	0	None	-275	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	494	10	2	5	5.4	FC(F)(F)Oc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5192791	198200	0	None	-275	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	494	10	2	5	5.4	FC(F)(F)Oc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	91809285	132540	0	None	-323	6	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1880	34	19	19	5.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647686	132540	0	None	-323	6	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1880	34	19	19	5.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	91809301	132554	0	None	-831	4	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1470	22	17	16	2.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647700	132554	0	None	-831	4	Human	7.4	pKi	=	7.4	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1470	22	17	16	2.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	9985523	105937	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	572	17	2	6	6.2	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)C[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL281200	105937	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	572	17	2	6	6.2	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2ccccc2)C[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL408987	219519	0	None	-2	5	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC(=O)CNC1=O	10.1021/jm9806289
	CHEMBL410181	219584	0	None	-1	5	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)C[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	9848232	108930	0	None	-6	3	Human	5.4	pKi	=	5.4	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	485	8	4	3	3.7	NCCCCNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(C=Cc3ccccc32)CC1	10.1021/jm980194h
	CHEMBL302567	108930	0	None	-6	3	Human	5.4	pKi	=	5.4	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	485	8	4	3	3.7	NCCCCNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(C=Cc3ccccc32)CC1	10.1021/jm980194h
	142471733	197344	0	None	-75	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	394	7	2	4	4.4	CC(C)(C)Cc1nnc(Cc2c[nH]c3cc(F)ccc23)n1CCCc1c[nH]cn1	10.1039/D1MD00044F
	CHEMBL5180116	197344	0	None	-75	2	Human	5.4	pKi	=	5.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	394	7	2	4	4.4	CC(C)(C)Cc1nnc(Cc2c[nH]c3cc(F)ccc23)n1CCCc1c[nH]cn1	10.1039/D1MD00044F
	CHEMBL407195	219425	0	None	-21	4	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(F)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc(F)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	10699714	106193	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL282803	106193	0	None	-2	5	Human	5.4	pKi	=	5.4	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	678	20	2	7	7.4	NCCCCCOC[C@@H]1O[C@H](OCCc2c[nH]c3ccccc23)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1	10.1021/jm9800346
	73348312	96013	0	None	-4897	2	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	410	3	3	2	6.2	CC1(C2CCCCC2)N[C@H](c2nc(-c3ccccc3)c[nH]2)Cc2c1[nH]c1ccccc21	10.1021/jm0108449
	CHEMBL2367844	96013	0	None	-4897	2	Human	5.4	pKi	=	5.4	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	ChEMBL	410	3	3	2	6.2	CC1(C2CCCCC2)N[C@H](c2nc(-c3ccccc3)c[nH]2)Cc2c1[nH]c1ccccc21	10.1021/jm0108449
	CHEMBL439005	220596	0	None	-8	4	Human	6.4	pKi	=	6.4	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(Cl)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	168274800	196871	0	None	-630	2	Human	6.4	pKi	=	6.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	2	6	3.8	CS(=O)(=O)c1cccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5172814	196871	0	None	-630	2	Human	6.4	pKi	=	6.4	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	492	9	2	6	3.8	CS(=O)(=O)c1cccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	16062816	12836	0	None	-1479	5	Human	5.4	pKi	=	5.4	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	473	9	2	7	5.1	CCOc1cc(CN2CCC(Nc3nc4cc(C(=O)O)ccc4o3)CC2)cc(OCC)c1Cl	10.1016/j.bmcl.2009.09.024
	CHEMBL1080585	12836	0	None	-1479	5	Human	5.4	pKi	=	5.4	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	473	9	2	7	5.1	CCOc1cc(CN2CCC(Nc3nc4cc(C(=O)O)ccc4o3)CC2)cc(OCC)c1Cl	10.1016/j.bmcl.2009.09.024
	86294248	125598	1	None	-1023	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	298	3	2	4	1.4	Cn1nc(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)c2ccccc21	10.1021/ml500538a
	CHEMBL3421843	125598	1	None	-1023	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	298	3	2	4	1.4	Cn1nc(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)c2ccccc21	10.1021/ml500538a
	71458043	85678	0	None	-3	5	Human	5.3	pKi	=	5.3	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	494	10	3	5	4.3	CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(Cc3ccccc3)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	CHEMBL2112934	85678	0	None	-3	5	Human	5.3	pKi	=	5.3	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	494	10	3	5	4.3	CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(Cc3ccccc3)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	142471924	197173	0	None	-524	3	Human	6.3	pKi	=	6.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	432	8	2	4	4.6	Fc1ccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5177573	197173	0	None	-524	3	Human	6.3	pKi	=	6.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	432	8	2	4	4.6	Fc1ccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	91809300	132553	0	None	-602	4	Human	7.3	pKi	=	7.3	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1454	22	16	15	2.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647699	132553	0	None	-602	4	Human	7.3	pKi	=	7.3	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1454	22	16	15	2.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	142471772	197957	0	None	-870	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	488	9	2	4	5.3	Brc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5189042	197957	0	None	-870	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	488	9	2	4	5.3	Brc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	56945132	178199	0	None	-251	3	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF from SST1 receptor (unknown origin) after 90 mins by gamma counting methodDisplacement of [125I]-Tyr-SRIF from SST1 receptor (unknown origin) after 90 mins by gamma counting method	ChEMBL	478	9	2	4	5.8	Clc1ccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1Cl	10.1039/C8MD00388B
	CHEMBL4462793	178199	0	None	-251	3	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF from SST1 receptor (unknown origin) after 90 mins by gamma counting methodDisplacement of [125I]-Tyr-SRIF from SST1 receptor (unknown origin) after 90 mins by gamma counting method	ChEMBL	478	9	2	4	5.8	Clc1ccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1Cl	10.1039/C8MD00388B
	CHEMBL415201	219959	0	None	-13	4	Human	6.3	pKi	=	6.3	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(F)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	46882133	12580	0	None	-27	7	Human	5.3	pKi	=	5.3	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	478	9	2	7	5.1	CCOc1cc(CN2CCC(Nc3nc4cc(NC(=O)C5CCC5)ccc4o3)CC2)ccc1OC	10.1016/j.bmcl.2009.09.024
	CHEMBL1078896	12580	0	None	-27	7	Human	5.3	pKi	=	5.3	Binding	Displacement of SST14 from human recombinant SST1 receptorDisplacement of SST14 from human recombinant SST1 receptor	ChEMBL	478	9	2	7	5.1	CCOc1cc(CN2CCC(Nc3nc4cc(NC(=O)C5CCC5)ccc4o3)CC2)ccc1OC	10.1016/j.bmcl.2009.09.024
	91809308	132561	0	None	-15	4	Human	8.3	pKi	=	8.3	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1602	27	18	16	4.2	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647707	132561	0	None	-15	4	Human	8.3	pKi	=	8.3	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1602	27	18	16	4.2	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	9857566	66834	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	302	4	3	2	3.8	N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	CHEMBL173715	66834	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	302	4	3	2	3.8	N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	6918011	215380	28	None	-1000	4	Human	6.3	pKi	=	6.3	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm021093t
	CHEMBL1201185	215380	28	None	-1000	4	Human	6.3	pKi	=	6.3	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm021093t
	DB06791	215380	28	None	-1000	4	Human	6.3	pKi	=	6.3	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC1=O	10.1021/jm021093t
	11963995	98640	0	None	-295	3	Human	5.3	pKi	=	5.3	Binding	Binding affinity to human SST1RBinding affinity to human SST1R	ChEMBL	387	6	1	4	3.8	CCOc1cc(CN2CCC(NC(=O)c3cncc(C)c3)CC2)ccc1Cl	10.1021/jm701144e
	CHEMBL241329	98640	0	None	-295	3	Human	5.3	pKi	=	5.3	Binding	Binding affinity to human SST1RBinding affinity to human SST1R	ChEMBL	387	6	1	4	3.8	CCOc1cc(CN2CCC(NC(=O)c3cncc(C)c3)CC2)ccc1Cl	10.1021/jm701144e
	CHEMBL413171	219830	0	None	-4	5	Human	6.3	pKi	=	6.3	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(F)c(F)c(F)c(F)c2F)CSSC[C@H](C(=O)N[C@@H](Cc2c(F)c(F)c(F)c(F)c2F)C(N)=O)NC1=O	10.1021/jm9806289
	11705763	175094	0	None	-1380	5	Human	6.3	pKi	=	6.3	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	484	10	2	7	5.4	Cc1cccc2c(C(=O)CCSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12	10.1016/j.bmcl.2005.05.061
	CHEMBL434159	175094	0	None	-1380	5	Human	6.3	pKi	=	6.3	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	484	10	2	7	5.4	Cc1cccc2c(C(=O)CCSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12	10.1016/j.bmcl.2005.05.061
	142471677	198728	0	None	-1621	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	478	9	2	4	5.5	FC(F)(F)c1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5200786	198728	0	None	-1621	2	Human	5.3	pKi	=	5.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	478	9	2	4	5.5	FC(F)(F)c1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	44308836	109568	0	None	-134	5	Human	6.3	pKi	=	6.3	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NCC1CCCC(CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	CHEMBL305279	109568	0	None	-134	5	Human	6.3	pKi	=	6.3	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	539	7	4	3	4.7	NCC1CCCC(CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1	10.1021/jm980194h
	9827283	85363	0	None	-117	4	Human	5.3	pKi	=	5.3	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	499	9	4	3	4.1	NCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(C=Cc3ccccc32)CC1	10.1021/jm980194h
	CHEMBL2112223	85363	0	None	-117	4	Human	5.3	pKi	=	5.3	Binding	Binding affinity towards human sst1 receptor expressed in CHO-K1 cellsBinding affinity towards human sst1 receptor expressed in CHO-K1 cells	ChEMBL	499	9	4	3	4.1	NCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(C=Cc3ccccc32)CC1	10.1021/jm980194h
	142471936	198274	0	None	-776	5	Human	6.3	pKi	=	6.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	482	8	2	4	5.5	Fc1ccc2c(Cc3nnc(Cc4cccc(C(F)(F)F)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5193727	198274	0	None	-776	5	Human	6.3	pKi	=	6.3	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	482	8	2	4	5.5	Fc1ccc2c(Cc3nnc(Cc4cccc(C(F)(F)F)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL437057	220482	0	None	-3	3	Human	6.3	pKi	=	6.3	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(F)c(F)c(F)c(F)c2F)CSSC[C@H](C(=O)N[C@@H](Cc2c(F)c(F)c(F)c(F)c2F)C(N)=O)NC1=O	10.1021/jm9806289
	CHEMBL264028	217382	0	None	-32	5	Human	6.2	pKi	=	6.2	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(I)cc2)CSSC[C@H](C(=O)N[C@@H](Cc2ccc(I)cc2)C(N)=O)NC1=O	10.1021/jm9806289
	44397389	130822	0	None	-33	5	Human	7.2	pKi	=	7.2	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	460	9	2	6	5.2	NCCCCn1c(SCCc2c[nH]c3cc(F)ccc23)nnc1-c1ccc2ccccc2n1	10.1016/j.bmcl.2005.05.061
	CHEMBL363092	130822	0	None	-33	5	Human	7.2	pKi	=	7.2	Binding	Binding affinity against human sst1 receptor at a dose of 10 uMBinding affinity against human sst1 receptor at a dose of 10 uM	ChEMBL	460	9	2	6	5.2	NCCCCn1c(SCCc2c[nH]c3cc(F)ccc23)nnc1-c1ccc2ccccc2n1	10.1016/j.bmcl.2005.05.061
	142471730	197164	0	None	-741	3	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	464	8	2	4	5.3	FC(F)(F)c1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5177487	197164	0	None	-741	3	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	464	8	2	4	5.3	FC(F)(F)c1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	91809302	132555	0	None	-26	3	Human	7.2	pKi	=	7.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1439	23	16	14	3.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647701	132555	0	None	-26	3	Human	7.2	pKi	=	7.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1439	23	16	14	3.7	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	91809291	132544	0	None	-120	4	Human	8.2	pKi	=	8.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1473	23	16	14	2.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647690	132544	0	None	-120	4	Human	8.2	pKi	=	8.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1473	23	16	14	2.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	2018	9781	28	None	-50	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	9941444	9781	28	None	-50	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	CHEMBL3349607	9781	28	None	-50	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	DB06663	9781	28	None	-50	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		None	10.1021/jm021093t
	CHEMBL3349524	218202	0	None	-10	4	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O	10.1021/jm021093t
	CHEMBL3349604	218212	0	None	-15	5	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]2C[C@@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	91809286	132541	0	None	-41	6	Human	8.2	pKi	=	8.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1489	23	16	15	2.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCS(=O)(=O)C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647687	132541	0	None	-41	6	Human	8.2	pKi	=	8.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1489	23	16	15	2.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCS(=O)(=O)C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL411556	219665	0	None	1	4	Human	7.2	pKi	=	7.2	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2cccc(F)c2)CSSC[C@@H](C(=O)N[C@@H](Cc2cccc(F)c2)C(N)=O)NC1=O	10.1021/jm9806289
	142471891	197374	0	None	-436	4	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	430	8	2	4	5.0	Clc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL5180551	197374	0	None	-436	4	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	430	8	2	4	5.0	Clc1ccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1	10.1039/D1MD00044F
	CHEMBL3349599	218207	0	None	-199	5	Human	7.2	pKi	=	7.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O	10.1021/jm021093t
	CHEMBL421362	220053	0	None	-1258	5	Human	6.2	pKi	=	6.2	Binding	Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cellsBinding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells	ChEMBL		None	None	None		C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O	10.1021/jm021093t
	91809292	132545	0	None	-3235	4	Human	7.2	pKi	=	7.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1619	27	18	17	2.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647691	132545	0	None	-3235	4	Human	7.2	pKi	=	7.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1619	27	18	17	2.6	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	90644981	118590	0	None	-173	4	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]SS14 from human SST1 expressed in CHO membrane after 60 to 90 mins by scintillation countingDisplacement of [125I]SS14 from human SST1 expressed in CHO membrane after 60 to 90 mins by scintillation counting	ChEMBL	365	5	3	2	4.1	O=C(N[C@@H]1CCCC[C@@H]1NCc1c[nH]c2ccccc12)c1ccc(F)cc1	10.1021/ml500079u
	CHEMBL3287613	118590	0	None	-173	4	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]SS14 from human SST1 expressed in CHO membrane after 60 to 90 mins by scintillation countingDisplacement of [125I]SS14 from human SST1 expressed in CHO membrane after 60 to 90 mins by scintillation counting	ChEMBL	365	5	3	2	4.1	O=C(N[C@@H]1CCCC[C@@H]1NCc1c[nH]c2ccccc12)c1ccc(F)cc1	10.1021/ml500079u
	142471678	196821	0	None	-660	2	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	474	9	2	6	3.7	CS(=O)(=O)c1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5171935	196821	0	None	-660	2	Human	6.2	pKi	=	6.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	474	9	2	6	3.7	CS(=O)(=O)c1cccc(Cc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	10554930	106968	0	None	-2	5	Human	5.2	pKi	=	5.2	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	562	17	3	7	4.9	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2c[nH]cn2)C[C@@H]1OCc1ccccc1	10.1021/jm9800346
	CHEMBL28824	106968	0	None	-2	5	Human	5.2	pKi	=	5.2	Binding	Binding affinity for human receptor subtype hSSTR1Binding affinity for human receptor subtype hSSTR1	ChEMBL	562	17	3	7	4.9	NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2c[nH]cn2)C[C@@H]1OCc1ccccc1	10.1021/jm9800346
	91809296	132549	0	None	-34673	4	Human	6.2	pKi	=	6.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1488	23	17	17	1.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCS(=O)(=O)C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647695	132549	0	None	-34673	4	Human	6.2	pKi	=	6.2	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1488	23	17	17	1.5	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCCS(=O)(=O)C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL414598	219925	0	None	1	4	Human	7.2	pKi	=	7.2	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(F)c(F)c(F)c(F)c2F)CSSC[C@@H](C(=O)N[C@@H](Cc2c(F)c(F)c(F)c(F)c2F)C(N)=O)NC1=O	10.1021/jm9806289
	142471767	199061	0	None	-1348	2	Human	5.2	pKi	=	5.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	4	5.1	Clc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5205904	199061	0	None	-1348	2	Human	5.2	pKi	=	5.2	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	4	5.1	Clc1cccc(Cc2nnc(CCc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	44363816	46449	0	None	-194	5	Human	6.2	pKi	=	6.2	Binding	In vitro binding affinity was evaluated against human Somatostatin receptor type 1 (hSSTR-1)In vitro binding affinity was evaluated against human Somatostatin receptor type 1 (hSSTR-1)	ChEMBL	589	14	3	5	5.0	C[C@@H](c1c[nH]c2ccccc12)[C@H](C(=O)N[C@H](CCCCN)C(=O)OC(C)(C)C)N1CCN(CCCc2ccccc2)C1=O	10.1016/s0960-894x(99)00016-5
	CHEMBL147499	46449	0	None	-194	5	Human	6.2	pKi	=	6.2	Binding	In vitro binding affinity was evaluated against human Somatostatin receptor type 1 (hSSTR-1)In vitro binding affinity was evaluated against human Somatostatin receptor type 1 (hSSTR-1)	ChEMBL	589	14	3	5	5.0	C[C@@H](c1c[nH]c2ccccc12)[C@H](C(=O)N[C@H](CCCCN)C(=O)OC(C)(C)C)N1CCN(CCCc2ccccc2)C1=O	10.1016/s0960-894x(99)00016-5
	CHEMBL2372959	217104	0	None	-2	5	Human	6.1	pKi	=	6.1	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)C2Cc3ccccc3C2)CSSC[C@@H](C(=O)N[C@H](C(N)=O)C2Cc3ccccc3C2)NC1=O	10.1021/jm9806289
	117711399	125600	0	None	-104	2	Human	5.1	pKi	=	5.1	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	310	3	2	4	1.8	Cc1nc(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)c2ccccc2n1	10.1021/ml500538a
	CHEMBL3421845	125600	0	None	-104	2	Human	5.1	pKi	=	5.1	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	310	3	2	4	1.8	Cc1nc(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)c2ccccc2n1	10.1021/ml500538a
	91809290	132543	0	None	-213	4	Human	8.1	pKi	=	8.1	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1636	27	18	16	3.3	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647689	132543	0	None	-213	4	Human	8.1	pKi	=	8.1	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1636	27	18	16	3.3	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL406152	219375	0	None	1	4	Human	7.1	pKi	=	7.1	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2cccc(F)c2)CSSC[C@H](C(=O)N[C@@H](Cc2cccc(F)c2)C(N)=O)NC1=O	10.1021/jm9806289
	90665461	116038	0	None	-4	5	Human	5.1	pKi	=	5.1	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	807	13	3	7	4.3	C[C@@H](O)CN1CCC(=O)N(Cc2ccccc2)CCC(=O)N(Cc2ccccc2)CCC(=O)N(CCc2c[nH]c3ccccc23)CCC(=O)N(CCCCN)CCC1=O	10.1039/C2MD20265D
	CHEMBL3218123	116038	0	None	-4	5	Human	5.1	pKi	=	5.1	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	ChEMBL	807	13	3	7	4.3	C[C@@H](O)CN1CCC(=O)N(Cc2ccccc2)CCC(=O)N(Cc2ccccc2)CCC(=O)N(CCc2c[nH]c3ccccc23)CCC(=O)N(CCCCN)CCC1=O	10.1039/C2MD20265D
	CHEMBL406738	219397	0	None	-11	5	Human	6.1	pKi	=	6.1	Binding	The compound was tested for binding affinity against human Somatostatin receptor type 1The compound was tested for binding affinity against human Somatostatin receptor type 1	ChEMBL		None	None	None		CC(C)CC[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc3ccccc3c2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)NC1=O	10.1021/jm9806289
	86293506	125597	0	None	-229	2	Human	6.1	pKi	=	6.1	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	309	3	2	3	2.4	Cc1cc2ccccc2c(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)n1	10.1021/ml500538a
	CHEMBL3421842	125597	0	None	-229	2	Human	6.1	pKi	=	6.1	Binding	Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 minsDisplacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mins	ChEMBL	309	3	2	3	2.4	Cc1cc2ccccc2c(C(C)(C)NC(=O)[C@@H]2[C@H]3CNC[C@H]32)n1	10.1021/ml500538a
	168275406	197086	0	None	-794	4	Human	6.1	pKi	=	6.1	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	482	8	2	4	5.7	Fc1ccc2c(Cc3nnc(Cc4ccc(Cl)c(Cl)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5176083	197086	0	None	-794	4	Human	6.1	pKi	=	6.1	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	482	8	2	4	5.7	Fc1ccc2c(Cc3nnc(Cc4ccc(Cl)c(Cl)c4)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	13690207	122160	0	None	-812	5	Human	6.1	pKi	=	6.1	Binding	Binding affinity towards somatostatin receptor type 1Binding affinity towards somatostatin receptor type 1	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1021/jm050376t
	CHEMBL3350037	122160	0	None	-812	5	Human	6.1	pKi	=	6.1	Binding	Binding affinity towards somatostatin receptor type 1Binding affinity towards somatostatin receptor type 1	ChEMBL	1018	17	13	14	-0.8	C[C@@H](O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1	10.1021/jm050376t
	91809276	132531	0	None	-26	6	Human	8.1	pKi	=	8.1	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1620	27	18	16	4.3	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	CHEMBL3647677	132531	0	None	-26	6	Human	8.1	pKi	=	8.1	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1620	27	18	16	4.3	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O	nan
	91809294	132547	0	None	-1148	4	Human	7.0	pKi	=	7.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1912	34	19	19	3.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	CHEMBL3647693	132547	0	None	-1148	4	Human	7.0	pKi	=	7.0	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1912	34	19	19	3.8	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC[C@H](CCCCNC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)NC(=O)C[S+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccccc2)NC1=O	nan
	44385591	138165	0	None	-38	2	Human	5.0	pKi	=	5.0	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	488	7	3	2	6.2	O=C(Cc1cccc(C(F)(F)F)c1)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	CHEMBL368993	138165	0	None	-38	2	Human	5.0	pKi	=	5.0	Binding	Inhibition of human sst1 receptor expressed in CHO cellsInhibition of human sst1 receptor expressed in CHO cells	ChEMBL	488	7	3	2	6.2	O=C(Cc1cccc(C(F)(F)F)c1)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1	10.1016/s0960-894x(01)00107-x
	142471832	197054	0	None	-138	5	Human	7.0	pKi	=	7.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	471	8	3	4	5.1	Fc1ccc2c(Cc3nnc(Cc4c[nH]c5cc(F)ccc45)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	CHEMBL5175637	197054	0	None	-138	5	Human	7.0	pKi	=	7.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	471	8	3	4	5.1	Fc1ccc2c(Cc3nnc(Cc4c[nH]c5cc(F)ccc45)n3CCCc3c[nH]cn3)c[nH]c2c1	10.1039/D1MD00044F
	10096510	64202	0	None	-26	4	Human	5.0	pKi	=	5.0	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	475	7	2	6	5.2	CC(C)(C(=O)NC1CCCCC1)c1cn2cc(-c3csc4ccccc34)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	CHEMBL165402	64202	0	None	-26	4	Human	5.0	pKi	=	5.0	Binding	Inhibitory constant on human Somatostatin receptor type 1Inhibitory constant on human Somatostatin receptor type 1	ChEMBL	475	7	2	6	5.2	CC(C)(C(=O)NC1CCCCC1)c1cn2cc(-c3csc4ccccc34)nc(CCCN)c2n1	10.1016/s0960-894x(01)00051-8
	168279197	197711	0	None	-1621	4	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1cccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	CHEMBL5185547	197711	0	None	-1621	4	Human	6.0	pKi	=	6.0	Binding	Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisDisplacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysis	ChEMBL	444	9	2	5	4.4	COc1cccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)c1	10.1039/D1MD00044F
	91809288	132542	0	None	-562	6	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1472	23	17	16	1.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S@@+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647688	132542	0	None	-562	6	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1472	23	17	16	1.9	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NCC[S@@+]([O-])C[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	91809312	132565	0	None	-588	3	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1754	28	17	18	6.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N(CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	CHEMBL3647711	132565	0	None	-588	3	Human	7.0	pKi	=	7	Binding	Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.Radioligand Binding Assay: Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors were homogenized in ice-cold buffer with 10 mM Tris-HCl, 5 mM EDTA, 3 mM EGTA, 1 mM phenylmethylsuphonyl fluoride, pH 7.6, using Polytron PT10-35GT (Kinematica) at 18,000 rpm for 30 seconds and centrifuged at 500xg for 10 minutes. The supernatant containing the plasma membranes was centrifuged at 100,000xg for 30 minutes and the pellet was resuspended in buffer containing 20 mM glycine-glycine, 1 mM MgCl2, 250 mM sucrose, pH 7.2, for storage at -80 C.For the SSTR1, 2 and 5 assays, membranes and various concentrations of test compounds were incubated in 96-well plates for 60 minutes at 25 C. with 0.05 nM [125I-Tyr11]-SRIF-14 (for hSSTR1; PerkinElmer Life Science), 0.05 nM [125I-Tyr]-seglitide (for hSSTR2; PerkinElmer Life Science) or 0.05 nM [125I-Tyr]-[DPhe-cyclo(Cys-Tyr-DTrp-Lys-Val-Cys)-Thr-NH2] (for hSSTR5.	ChEMBL	1754	28	17	18	6.4	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccncc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N(CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O	nan
	2030	10444	10	None	-13	10	Human	8.1	pKd	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	15135911
	5311377	10444	10	None	-13	10	Human	8.1	pKd	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	15135911
	CHEMBL251541	10444	10	None	-13	10	Human	8.1	pKd	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	464	4	0	6	3.0	COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]	15135911
	16161315	222875	0	125I-CGP23996	-6	13	Human	10.0	pKi	=	10	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr11-SRIF	-6	13	Human	10.0	pKi	=	10	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	UNDEFINED	-6	13	Human	10.0	pKi	=	10	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr11-somatostatin	-3	13	Rat	10.0	pKi	=	10	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr11-somatostatin-14	-3	13	Rat	9.7	pKi	=	9.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr11-SRIF-14	-6	13	Human	9.5	pKi	=	9.5	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-LTT-SST-28	-6	13	Human	9.4	pKi	=	9.4	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-LTT-SST-28	-6	13	Human	9.4	pKi	=	9.4	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr11-SRIF	-6	13	Human	9.3	pKi	=	9.3	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-SOMATOSTATIN 14	-6	13	Human	9.2	pKi	=	9.2	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-SRIF	-6	13	Human	9.2	pKi	=	9.2	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-SRIF-28	-6	13	Human	9.2	pKi	=	9.2	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-LTT-SRIF28	-6	13	Human	9.1	pKi	=	9.1	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-LTT-SRIF28	-6	13	Human	9.1	pKi	=	9.1	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr11-SRIF	-6	13	Human	9.1	pKi	=	9.1	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr10-CST14	-6	13	Human	9.1	pKi	=	9.1	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr11-somatostatin-14	-6	13	Human	9.0	pKi	=	9	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-LTT-SST-28	-6	13	Human	9.0	pKi	=	9.0	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-CGP23996	-6	13	Human	9.0	pKi	=	9.0	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	2055	9682	48	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-CGP23996	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-LTT-SST-28	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-Tyr11-SRIF	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	10746	15	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	10746	15	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-LTT-SST-28	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	UNDEFINED	-741	11	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	222876	0	125I-CGP23996	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	222876	0	125I-LTT-SST-28	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	222876	0	125I-SOMATOSTATIN	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	222876	0	125I-SRIF	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	222876	0	125I-SRIF-28	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	222876	0	125I-Tyr11-SRIF	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	222876	0	125I-Tyr11-somatostatin-14	-19054	12	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	13105142	222877	0	UNDEFINED	-30199	5	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	808	11	8	8	2.0	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O	None
	None	222876	0	125I-LTT-SST-28	-19054	12	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	None	222876	0	125I-Tyr11-SRIF	-19054	12	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	868	11	9	9	2.1	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O.CC(=O)O	None
	13105142	222877	0	125I-CGP23996	-30199	5	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	808	11	8	8	2.0	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O	None
	13105142	222877	0	125I-LTT-SRIF28	-30199	5	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	808	11	8	8	2.0	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O	None
	13105142	222877	0	125I-Tyr10-CST14	-30199	5	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	808	11	8	8	2.0	CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O	None
	None	223127	0	125I-LTT-SST-28	-93	5	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	584	17	5	8	2.8	CCCCC(C(=O)NC(CCCCN)C(=O)OC)NC(=O)NC(CC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-]	None
	2054	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-Tyr10-CST14	-741	11	Human	7.0	pKi	=	7.0	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-Tyr11-somatostatin-14	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-Tyr11-SRIF	-1047	14	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	223127	0	125I-LTT-SST-28	-93	5	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase	584	17	5	8	2.8	CCCCC(C(=O)NC(CCCCN)C(=O)OC)NC(=O)NC(CC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-]	None
	None	223127	0	UNDEFINED	-93	5	Human	5.9	pKi	=	5.9	Binding	NoneNone	PDSP KiDatabase	584	17	5	8	2.8	CCCCC(C(=O)NC(CCCCN)C(=O)OC)NC(=O)NC(CC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-]	None
	2054	10746	15	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	10746	15	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-SRIF-28	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-Tyr11-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	10746	15	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-SRIF	-741	11	Human	6.8	pKi	=	6.8	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	223125	0	125I-Tyr11-somatostatin-14	-112	9	Human	7.7	pKi	=	7.7	Binding	NoneNone	PDSP KiDatabase	1077	14	12	13	0.6	CC(C1C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)N)C(=O)N)CC6=CC=CC=C6)O	None
	None	223125	0	UNDEFINED	-112	9	Human	7.7	pKi	=	7.7	Binding	NoneNone	PDSP KiDatabase	1077	14	12	13	0.6	CC(C1C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)N)C(=O)N)CC6=CC=CC=C6)O	None
	None	223128	0	125I-LTT-SST-28	-537	5	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase	485	11	4	4	3.1	COC(=O)C(CCCN=C(N)N)NC(=O)CCCC1=C(NC2=C(C=C(C=C12)F)F)C3=CC=CC=C3	None
	None	223128	0	UNDEFINED	-537	5	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase	485	11	4	4	3.1	COC(=O)C(CCCN=C(N)N)NC(=O)CCCC1=C(NC2=C(C=C(C=C12)F)F)C3=CC=CC=C3	None
	16161315	222875	0	125I-Tyr11-SRIF	-6	13	Human	8.7	pKi	=	8.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr11-somatostatin-14	-6	13	Human	8.7	pKi	=	8.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-SOMATOSTATIN	-6	13	Human	8.7	pKi	=	8.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	16161315	222875	0	125I-Tyr11-somatostatin-14	-6	13	Human	8.7	pKi	=	8.7	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	2055	9682	48	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-LTT-SRIF28	-1047	14	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	10746	15	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-CGP23996	-741	11	Human	6.7	pKi	=	6.7	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-LTT-SST-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-SRIF-28	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-SOMATOSTATIN 14	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-SRIF	-1047	14	Human	6.6	pKi	=	6.6	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	223126	0	125I-LTT-SST-28	-54954	5	Human	5.6	pKi	=	5.6	Binding	NoneNone	PDSP KiDatabase	585	8	5	5	4.2	CC(C1=CNC2=CC=CC=C21)C(C(=O)NCC3CCCC(C3)CN)NC(=O)N4CCC(CC4)N5C6=CC=CC=C6NC5=O	None
	None	223126	0	UNDEFINED	-54954	5	Human	5.6	pKi	=	5.6	Binding	NoneNone	PDSP KiDatabase	585	8	5	5	4.2	CC(C1=CNC2=CC=CC=C21)C(C(=O)NCC3CCCC(C3)CN)NC(=O)N4CCC(CC4)N5C6=CC=CC=C6NC5=O	None
	2055	9682	48	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	UNDEFINED	-1047	14	Human	6.5	pKi	=	6.5	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	223129	0	125I-LTT-SST-28	-4	5	Human	8.5	pKi	=	8.5	Binding	NoneNone	PDSP KiDatabase	536	11	4	5	5.2	CC(COC(=O)C(CCCCN)NC(=O)CC1=C(NC2=C1C=CC3=CC=CC=C32)C4=CC5=CC=CC=C5C=C4)N	None
	None	223129	0	UNDEFINED	-4	5	Human	8.5	pKi	=	8.5	Binding	NoneNone	PDSP KiDatabase	536	11	4	5	5.2	CC(COC(=O)C(CCCCN)NC(=O)CC1=C(NC2=C1C=CC3=CC=CC=C32)C4=CC5=CC=CC=C5C=C4)N	None
	2055	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-Tyr10-CST14	-1047	14	Human	6.4	pKi	=	6.4	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	16161315	222875	0	125I-Tyr11-SRIF	-3	13	Rat	8.4	pKi	=	8.4	Binding	NoneNone	PDSP KiDatabase	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	2054	10746	15	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-SOMATOSTATIN	-741	11	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2031	9053	0	UNDEFINED	-851	9	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71349	9053	0	UNDEFINED	-851	9	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB06791	9053	0	UNDEFINED	-851	9	Human	6.3	pKi	=	6.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	223274	0	125I-LTT-SST-28	-11220	5	Human	5.3	pKi	=	5.3	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	None	223125	0	125I-SOMATOSTATIN	-112	9	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase	1077	14	12	13	0.6	CC(C1C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)N)C(=O)N)CC6=CC=CC=C6)O	None
	2055	9682	48	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-CGP23996	-1047	14	Human	6.2	pKi	=	6.2	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	383414	9682	48	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	448601	9682	48	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	90488715	9682	48	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	CHEMBL1680	9682	48	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	CHEMBL262746	9682	48	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	DB00104	9682	48	None	-1047	14	Human	8.2	pKi	=	8.2	Binding	Displacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysisDisplacement of [125I]-somatostatin from human sst1 receptor after 2 hrs by beta scintillation counting analysis	Drug Central		None	None	None		None	None
	2054	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2054	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	71306	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL264186	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL3349523	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB04894	10746	15	125I-LTT-SRIF28	-741	11	Human	7.1	pKi	=	7.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	2055	9682	48	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	383414	9682	48	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	448601	9682	48	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	90488715	9682	48	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL1680	9682	48	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	CHEMBL262746	9682	48	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	DB00104	9682	48	125I-SOMATOSTATIN	-1047	14	Human	6.1	pKi	=	6.1	Binding	NoneNone	PDSP KiDatabase		None	None	None		None	None
	16161315	222875	0	None	-6	13	Human	8.0	pKi	=	8.0	Binding	Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeInhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtype	Drug Central	1637	26	22	23	-4.9	C[C@@H](C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)CC(=O)N)CC2=CC=CC=C2)CC3=CC=CC=C3)CC4=CNC5=CC=CC=C54)CCCCN)C(C)O)CC6=CC=CC=C6)C(C)O)CO)C(=O)O)N	None
	2028	8288	0	None	-2238	6	Human	5.2	pKi	=	5.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	12616335
	2029	9154	0	None	-281	6	Human	5.8	pKi	=	5.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	12616335
	2014	8995	0	None	-281	9	Human	6.2	pKi	=	6.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2014	8995	0	None	-281	9	Human	6.2	pKi	=	6.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2017	9520	0	None	-10	3	Human	7.4	pKi	=	7.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	16130961	7678	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	16130961	7678	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	16130961	7678	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2005	7678	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2005	7678	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	2005	7678	0	None	-5	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2007	7953	0	None	-12	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2007	7953	0	None	-12	6	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2015	9037	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	607	16	3	4	6.2	NCCC(CC(CNC(=O)[C@@H](Cc1cccc2c1cccc2)NC(=O)N(CCc1ccccn1)CCc1ccccc1)(C)C)C	9784130
	9938757	9037	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	607	16	3	4	6.2	NCCC(CC(CNC(=O)[C@@H](Cc1cccc2c1cccc2)NC(=O)N(CCc1ccccn1)CCc1ccccc1)(C)C)C	9784130
	154734381	224493	0	None	1	9	Human	8.2	pKi	None	8.2	Binding	NoneNone	Drug Central	1095	17	13	14	0.8	CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@@H](N)CC1=CC=C2C=CC=CC2=C1	None
	2004	7429	0	None	-4	7	Human	8.4	pKi	None	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2004	7429	0	None	-4	7	Human	8.4	pKi	None	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	2004	7429	0	None	-4	7	Human	8.4	pKi	None	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2016	9040	4	None	-7	2	Human	8.5	pKi	None	8.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	536	11	4	5	5.2	NCCCC[C@@H](C(=O)OC[C@@H](N)C)NC(=O)Cc1c([nH]c2c1ccc1c2cccc1)c1ccc2c(c1)cccc2	9784130
	5311375	9040	4	None	-7	2	Human	8.5	pKi	None	8.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	536	11	4	5	5.2	NCCCC[C@@H](C(=O)OC[C@@H](N)C)NC(=O)Cc1c([nH]c2c1ccc1c2cccc1)c1ccc2c(c1)cccc2	9784130
	CHEMBL252764	9040	4	None	-7	2	Human	8.5	pKi	None	8.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	536	11	4	5	5.2	NCCCC[C@@H](C(=O)OC[C@@H](N)C)NC(=O)Cc1c([nH]c2c1ccc1c2cccc1)c1ccc2c(c1)cccc2	9784130
	16133849	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	16133849	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	16133849	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	16133849	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	16133849	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	16133849	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2020	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2020	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	2020	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	2020	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	2020	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	2020	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	91935900	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	91935900	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	91935900	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	91935900	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	91935900	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	91935900	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	CHEMBL501796	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	CHEMBL501796	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	CHEMBL501796	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	CHEMBL501796	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	CHEMBL501796	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	CHEMBL501796	10448	12	None	-7	9	Human	9.0	pKi	None	9	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2019	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2019	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11520208
	2019	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	2019	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	2019	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	2019	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	2019	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	2019	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9724791
	2019	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9784130
	44386062	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	44386062	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11520208
	44386062	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	44386062	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	44386062	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	44386062	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	44386062	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	44386062	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9724791
	44386062	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9784130
	CHEMBL440072	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	CHEMBL440072	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	11520208
	CHEMBL440072	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	CHEMBL440072	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	7988476
	CHEMBL440072	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	8769372
	CHEMBL440072	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9600011
	CHEMBL440072	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799
	CHEMBL440072	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9724791
	CHEMBL440072	10447	0	None	-4	10	Human	9.1	pKi	None	9.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9784130
	2008	7994	0	None	1	6	Human	9.4	pKi	None	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	10598788
	2008	7994	0	None	1	6	Human	9.4	pKi	None	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15333679
	2008	7994	0	None	1	6	Human	9.4	pKi	None	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	9650799

Join us

Cite us

Main reference

Ligand source activities (1 row/activity)