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Ligand source activities (1 row/activity)
Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Common name | GPCRdb ID | Reference ligand | Vendors | Species | Assay Type | Activity Type | Activity Relation | Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description | Source | Mol weight | Rot Bonds | H don | H acc | LogP | Smiles | DOI | |
Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Common name | GPCRdb ID | Reference ligand | Vendors | Species | Assay Type | Activity Type | Activity Relation | Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description | Source | Mol weight | Rot Bonds | H don | H acc | LogP | Smiles | DOI | |
| 1-(benzo[d]thiazol-2-yl)-N-(3-ethoxy-4-methoxyphenyl)piperidin-4-amine | 220110 | UNDEFINED | 0 | Human | Binding | pKi | = | 10000.00 | 5.00 | 1 | 3 | - | PDSP KiDatabase | 383.2 | 6 | 1 | 6 | 4.78 | CCOc1cc(NC2CCN(c3nc4ccccc4s3)CC2)ccc1OC | - | |
| 1-(benzo[d]thiazol-2-ylmethyl)-N-(3-ethoxy-4-methoxyphenyl)piperidin-4-amine | 220111 | UNDEFINED | 0 | Human | Binding | pKi | = | 10000.00 | 5.00 | 1 | 3 | - | PDSP KiDatabase | 397.2 | 7 | 1 | 6 | 4.78 | CCOc1cc(NC2CCN(Cc3nc4ccccc4s3)CC2)ccc1OC | - | |
| 2-(4-((4-(benzo[d]oxazol-2-ylamino)piperidin-1-yl)methyl)-2-ethoxy-5-fluorophenoxy)ethanol | 220122 | UNDEFINED | 0 | Human | Binding | pKi | = | 10000.00 | 5.00 | 1 | 3 | - | PDSP KiDatabase | 429.2 | 9 | 2 | 7 | 3.81 | CCOc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)c(F)cc1OCCO | - | |
| [D-Tyr8]CYN 154806 | 1506 | None | 0 | Human | Binding | pKd | = | - | 8.50 | 19 | 6 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/12616335 | |
| [L-Tyr8]CYN 154806 | 2375 | None | 0 | Human | Binding | pKi | = | - | 8.25 | 1 | 6 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/12616335 | |
| AC-178,335 | 234 | None | 0 | Rat | Binding | pKi | = | - | 6.80 | 1 | 2 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/9804621 | |
| ARSENIC TRIOXIDE | 197249 | None | 1 | Rat | Binding | Kd | = | 25118.86 | 4.60 | -478 | 2 | Displacement of [125I]SRIF14 from rat sst2 receptor from rat brain cortex membrane | ChEMBL | 197.8 | 1 | 0 | 3 | -2.19 | O=[As][As+](=O)[O-] | https://dx.doi.org/10.1016/j.bmcl.2007.04.078 | |
| astemizole | 505 | UNDEFINED | 55 | Human | Binding | pKi | = | 10000.00 | 5.00 | -5754 | 48 | - | PDSP KiDatabase | 458.2 | 8 | 1 | 5 | 5.35 | COc1ccc(CCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1 | - | |
| BASS antagonist | 576 | None | 0 | Human | Binding | pKi | = | - | 9.52 | - | 1 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8863814 | |
| BIM 23023 | 637 | None | 0 | Human | Binding | pKi | None | - | 9.40 | 1 | 8 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/7988476 | |
| BIM 23023 | 637 | None | 0 | Rat | Binding | pKi | = | - | 9.20 | -1 | 8 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/9600011 | |
| BIM 23023 | 637 | None | 0 | Mouse | Binding | pKi | = | - | 8.20 | -15 | 8 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/9600011 | |
| BIM 23030 | 639 | None | 0 | Human | Binding | pKi | = | - | 7.80 | 1 | 5 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/9650799 | |
| BIM 23030 | 639 | None | 0 | Human | Binding | pKi | = | - | 7.80 | 1 | 5 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/10598788 | |
| BIM 23030 | 639 | None | 0 | Human | Binding | pKi | = | - | 7.80 | 1 | 5 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/9652348 | |
| BIM 23034 | 640 | None | 0 | Human | Binding | pKi | = | - | 8.60 | 3 | 4 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/7988476 | |
| BIM 23052 | 642 | None | 0 | Human | Binding | pKi | = | - | 8.45 | -3 | 9 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8769372 | |
| BIM 23052 | 642 | None | 0 | Human | Binding | pKi | = | - | 8.45 | -3 | 9 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/9650799 | |
| BIM 23052 | 642 | None | 0 | Human | Binding | pKi | = | - | 8.45 | -3 | 9 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/10598788 | |
| BIM 23052 | 642 | None | 0 | Human | Binding | pKi | = | - | 8.45 | -3 | 9 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/9652348 | |
Showing 1 to 20 of 1,287 entries
Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Common name | GPCRdb ID | Reference ligand | Vendors | Species | Assay Type | Activity Type | Activity Relation | Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description | Source | Mol weight | Rot Bonds | H don | H acc | LogP | Smiles | DOI | |
Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Common name | GPCRdb ID | Reference ligand | Vendors | Species | Assay Type | Activity Type | Activity Relation | Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description | Source | Mol weight | Rot Bonds | H don | H acc | LogP | Smiles | DOI | |
| [Ga-DOTA,Tyr3,Thr8]octreotide | 1711 | None | 0 | Human | Functional | pIC50 | = | - | 9.70 | - | 1 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/17225119 | |
| [Ga-DOTA,Tyr3,Thr8]octreotide | 1711 | None | 0 | Human | Functional | pIC50 | = | - | 9.70 | - | 1 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/10774879 | |
| AM3 | 381 | None | 0 | Human | Functional | pIC50 | = | - | 8.64 | - | 1 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/20956465 | |
| analog 3 [PMID:18543899] | 411 | None | 0 | Human | Functional | pIC50 | = | - | 9.12 | - | 1 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/18543899 | |
| analog 30 [PMID:18543899] | 408 | None | 0 | Human | Functional | pIC50 | = | - | 8.77 | - | 1 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/18543899 | |
| analog 31 [PMID:18543899] | 409 | None | 0 | Human | Functional | pIC50 | = | - | 9.15 | - | 1 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/18543899 | |
| analog 32 [PMID:18543899] | 410 | None | 0 | Human | Functional | pIC50 | = | - | 8.92 | 380 | 2 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/18543899 | |
| BIM 23027 | 638 | None | 0 | Human | Functional | pIC50 | = | - | 10.85 | -1 | 3 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8646408 | |
| BIM 23027 | 638 | None | 0 | Rat | Functional | pIC50 | = | - | 9.70 | -25 | 3 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/9121614 | |
| BIM 23027 | 638 | None | 0 | Mouse | Functional | pIC50 | = | - | 11.10 | 1 | 3 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8100350 | |
| BIM 23027 | 638 | None | 0 | Mouse | Functional | pIC50 | = | - | 11.10 | 1 | 3 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8769370 | |
| BIM 23030 | 639 | None | 0 | Mouse | Functional | pIC50 | = | - | 8.20 | - | 5 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8100350 | |
| BIM 23034 | 640 | None | 0 | Mouse | Functional | pIC50 | = | - | 11.70 | 31622 | 4 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8100350 | |
| BIM 23059 | 645 | None | 0 | Mouse | Functional | pIC50 | = | - | 11.10 | 794 | 4 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8100350 | |
| BIM 23060 | 646 | None | 0 | Mouse | Functional | pIC50 | = | - | 10.90 | - | 3 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8100350 | |
| BIM 23066 | 647 | None | 0 | Mouse | Functional | pIC50 | = | - | 8.50 | -3 | 2 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8100350 | |
| BIM 23068 | 648 | None | 0 | Mouse | Functional | pIC50 | = | - | 9.80 | 5 | 6 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/8100350 | |
| BIM 23197 | 650 | None | 0 | Human | Functional | pIC50 | = | - | 9.70 | 50 | 3 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/9045884 | |
| BIM 23454 | 654 | None | 0 | Human | Functional | pIC50 | None | - | 7.50 | 1 | 5 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/11897676 | |
| BIM 23627 | 655 | None | 0 | Human | Functional | pIC50 | = | - | 8.20 | 6 | 5 | Unclassified | Guide to Pharmacology | - | - | - | - | - | - | https://pubmed.ncbi.nlm.nih.gov/11897676 | |
Showing 1 to 20 of 238 entries