Initializing potency table...
Ligand source activities (1 row/activity)
Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Common name | GPCRdb ID | Reference ligand | Vendors | Species | Assay Type | Activity Type | Activity Relation | Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description | Source | Mol weight | Rot Bonds | H don | H acc | LogP | Smiles | DOI | |
Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Common name | GPCRdb ID | Reference ligand | Vendors | Species | Assay Type | Activity Type | Activity Relation | Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description | Source | Mol weight | Rot Bonds | H don | H acc | LogP | Smiles | DOI | |
| CHEMBL1672755 | 58077 | None | 0 | Human | Binding | EC50 | = | 220.00 | 6.66 | - | 2 | Agonist activity at FFA3 (unknown origin) expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Lance cAMP assay | ChEMBL | 224.0 | 1 | 2 | 5 | 0.73 | CCc1cc(=O)oc2nc(S)[nH]c(=O)c12 | https://dx.doi.org/10.1039/d2md00076h | |
| CHEMBL2036813 | 75261 | None | 0 | Human | Binding | EC50 | = | 220.00 | 6.66 | - | 5 | Agonist activity at FFA3 (unknown origin) expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Lance cAMP assay | ChEMBL | 236.1 | 3 | 2 | 4 | 0.51 | CCCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 | https://dx.doi.org/10.1039/d2md00076h | |
| CHEMBL3185583 | 107552 | None | 63 | Rat | Binding | EC50 | = | 30000.00 | 4.52 | - | 1 | Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY22 co-expressing chimeric Gpa1/Galpha0 by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay | ChEMBL | 100.1 | 3 | 1 | 1 | 1.04 | C=CCCC(=O)O | - | |
| CHEMBL3188068 | 107600 | None | 10 | Rat | Binding | EC50 | = | 3000.00 | 5.52 | - | 1 | Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY22 co-expressing chimeric Gpa1/Galpha0 by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay | ChEMBL | 140.0 | 3 | 0 | 2 | -3.07 | CCCCC(=O)[O-].[K+] | - | |
| CHEMBL3890404 | 142569 | None | 7 | Rat | Binding | EC50 | = | 50000.00 | 4.30 | - | 1 | Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY22 co-expressing chimeric Gpa1/Galpha0 by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay | ChEMBL | 126.0 | 2 | 0 | 2 | -3.46 | CCCC(=O)[O-].[K+] | - | |
| CHEMBL3913375 | 145418 | None | 9 | Rat | Binding | EC50 | = | 30000.00 | 4.52 | - | 1 | Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY22 co-expressing chimeric Gpa1/Galpha0 by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay | ChEMBL | 154.0 | 4 | 0 | 2 | -2.68 | CCCCCC(=O)[O-].[K+] | - | |
| CHEMBL3925414 | 146975 | None | 9 | Rat | Binding | EC50 | = | 100000.00 | 4.00 | - | 1 | Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY22 co-expressing chimeric Gpa1/Galpha0 by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay | ChEMBL | 168.1 | 5 | 0 | 2 | -2.29 | CCCCCCC(=O)[O-].[K+] | - | |
| CHEMBL4530642 | 173609 | None | 0 | Rat | Binding | EC50 | = | 407.38 | 6.39 | - | 3 | Agonist activity at rat FFA3 receptor | ChEMBL | 418.1 | 3 | 2 | 3 | 5.62 | CC1=C(C(=O)Nc2cc(Cl)ccc2Cl)C(C2CCCC2)C2=C(CCCC2=O)N1 | https://dx.doi.org/10.1021/acs.jmedchem.9b02036 | |
| CHEMBL4530642 | 173609 | None | 0 | Mouse | Binding | EC50 | = | 1096.48 | 5.96 | - | 3 | Agonist activity at mouse FFA3 receptor | ChEMBL | 418.1 | 3 | 2 | 3 | 5.62 | CC1=C(C(=O)Nc2cc(Cl)ccc2Cl)C(C2CCCC2)C2=C(CCCC2=O)N1 | https://dx.doi.org/10.1021/acs.jmedchem.9b02036 | |
| CHEMBL4564389 | 175006 | None | 32 | Rat | Binding | EC50 | = | 457.09 | 6.34 | - | 3 | Agonist activity at rat FFA3 receptor | ChEMBL | 416.1 | 3 | 2 | 4 | 5.19 | CC1=C(C(=O)Nc2cc(Cl)ccc2Cl)C(c2ccco2)C2=C(CCCC2=O)N1 | https://dx.doi.org/10.1021/acs.jmedchem.9b02036 | |
| CHEMBL4564389 | 175006 | None | 32 | Mouse | Binding | EC50 | = | 1318.26 | 5.88 | - | 3 | Agonist activity at mouse FFA3 receptor | ChEMBL | 416.1 | 3 | 2 | 4 | 5.19 | CC1=C(C(=O)Nc2cc(Cl)ccc2Cl)C(c2ccco2)C2=C(CCCC2=O)N1 | https://dx.doi.org/10.1021/acs.jmedchem.9b02036 | |
| CHEMBL5270112 | 193728 | None | 0 | Human | Binding | EC50 | = | 220.00 | 6.66 | - | 3 | Agonist activity at FFA3 (unknown origin) expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Lance cAMP assay | ChEMBL | 252.1 | 3 | 2 | 4 | 1.88 | CCCCc1cc(=O)oc2[nH]c(=S)[nH]c(=O)c12 | https://dx.doi.org/10.1039/d2md00076h | |
| CHEMBL5275861 | 193981 | None | 0 | Human | Binding | EC50 | = | 220.00 | 6.66 | - | 3 | Agonist activity at FFA3 (unknown origin) expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Lance cAMP assay | ChEMBL | 286.0 | 4 | 2 | 4 | 2.10 | O=c1cc(CCCCCl)c2c(=O)[nH]c(=S)[nH]c2o1 | https://dx.doi.org/10.1039/d2md00076h | |
| CHEMBL5277000 | 194030 | None | 0 | Human | Binding | EC50 | = | 220.00 | 6.66 | - | 2 | Agonist activity at FFA3 (unknown origin) expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Lance cAMP assay | ChEMBL | 238.0 | 2 | 2 | 4 | 1.49 | CCCc1cc(=O)oc2[nH]c(=S)[nH]c(=O)c12 | https://dx.doi.org/10.1039/d2md00076h | |
| CHEMBL5281556 | 194224 | None | 11 | Human | Binding | EC50 | = | 220.00 | 6.66 | - | 2 | Agonist activity at FFA3 (unknown origin) expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Lance cAMP assay | ChEMBL | 210.0 | 0 | 2 | 4 | 0.85 | Cc1cc(=O)oc2[nH]c(=S)[nH]c(=O)c12 | https://dx.doi.org/10.1039/d2md00076h | |
| CHEMBL5284951 | 194381 | None | 0 | Human | Binding | EC50 | = | 220.00 | 6.66 | - | 3 | Agonist activity at FFA3 (unknown origin) expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Lance cAMP assay | ChEMBL | 270.0 | 4 | 2 | 4 | 0.73 | O=c1[nH]c(=O)c2c(CCCCCl)cc(=O)oc2[nH]1 | https://dx.doi.org/10.1039/d2md00076h | |
| FHQC | 1637 | None | 18 | Rat | Binding | EC50 | = | 1348.96 | 5.87 | - | 3 | Agonist activity at rat FFA3 receptor | ChEMBL | 362.2 | 3 | 2 | 4 | 4.20 | CC1=C(C(=O)Nc2ccccc2C)C(c2ccco2)C2=C(CCCC2=O)N1 | https://dx.doi.org/10.1021/acs.jmedchem.9b02036 | |
| FHQC | 1637 | None | 18 | Mouse | Binding | EC50 | = | 3801.89 | 5.42 | - | 3 | Agonist activity at mouse FFA3 receptor | ChEMBL | 362.2 | 3 | 2 | 4 | 4.20 | CC1=C(C(=O)Nc2ccccc2C)C(c2ccco2)C2=C(CCCC2=O)N1 | https://dx.doi.org/10.1021/acs.jmedchem.9b02036 | |
| isobutyric acid | 2089 | None | 44 | Rat | Binding | EC50 | = | 30000.00 | 4.52 | - | 3 | Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY22 co-expressing chimeric Gpa1/Galpha0 by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay | ChEMBL | 88.1 | 1 | 1 | 1 | 0.73 | CC(C)C(=O)O | - | |
| SODIUM PROPIONATE | 188442 | None | 49 | Rat | Binding | EC50 | = | 5000.00 | 5.30 | - | 1 | Agonist activity at rat GPR41 expressed in Saccharomyces cerevisiae MMY22 co-expressing chimeric Gpa1/Galpha0 by induction of FUSl-lacZ and FUS1-HIS3 reporter gene induction based pheromone response pathway coupled assay | ChEMBL | 96.0 | 1 | 0 | 2 | -3.85 | CCC(=O)[O-].[Na+] | - | |
Showing 1 to 20 of 20 entries
| Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Common name |
GPCRdb ID |
Reference ligand |
Vendors | Species | Assay Type |
Activity Type |
Activity Relation |
Activity Value |
p-value (-log) |
Fold selectivity |
Tested GPCRs |
Assay Description |
Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI | |