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Ligand source activities (1 row/activity)

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

ABLUKAST	83516	None	25	Guinea pig	Binding	IC50	=	4000.00	5.40	-	2	Compound was evaluated for its ability to displace [3H]LTD4 from LTD4 receptor in guinea pig lung membranes	ChEMBL	498.2	13	2	7	5.16	CCCc1c(OCCCCCOc2cc3c(cc2C(C)=O)CCC(C(=O)O)O3)ccc(C(C)=O)c1O	https://dx.doi.org/10.1021/jm00108a001
ABLUKAST	83516	None	25	Guinea pig	Binding	IC50	=	4000.00	5.40	-	2	Inhibitory activity of compound to block binding of [3H]leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lung	ChEMBL	498.2	13	2	7	5.16	CCCc1c(OCCCCCOc2cc3c(cc2C(C)=O)CCC(C(=O)O)O3)ccc(C(C)=O)c1O	https://dx.doi.org/10.1021/jm00128a028
BAY u9773	218707	3H-LTD4	0	Human	Binding	pKi	=	440.00	6.36	-1	2	-	PDSP KiDatabase	472.2	17	3	4	6.66	CCCCC/C=C\C/C=C/C=C/C=C/[C@@H](Sc1ccc(C(=O)O)cc1)[C@@H](O)CCCC(=O)O	-
BAYu9773	589	None	19	Guinea pig	Binding	Ki	=	100.00	7.00	-	4	Compound was evaluated for its binding affinity on guinea-pig ileum	ChEMBL	472.2	17	3	4	6.66	CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](Sc1ccc(C(=O)O)cc1)[C@@H](O)CCCC(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80009-8
CHEMBL1183712	12077	None	0	Guinea pig	Binding	Ki	=	2800.00	5.55	-	1	Binding affinity towards Cysteinyl leukotriene D4 receptor antagonist in guinea pig lung membranes	ChEMBL	357.1	5	1	3	5.16	C[C@H](C(=O)O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1	https://dx.doi.org/10.1021/jm00092a001
CHEMBL1204572	14589	None	0	Guinea pig	Binding	IC50	=	440.00	6.36	-	1	In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranes	ChEMBL	470.1	11	3	6	4.90	O=C(O)CCSC(SCCC(=O)O)c1cccc(NC(=O)c2ccc3ccccc3n2)c1	https://dx.doi.org/10.1021/jm00099a011
CHEMBL1204684	14595	None	0	Guinea pig	Binding	IC50	=	1.30	8.89	-	1	Inhibition of [3H]LTD4 binding to guinea-pig lung membrane	ChEMBL	539.2	13	2	4	8.66	CC(C)(O)CCCSC(CCC(C)(C)CC(=O)O)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1	https://dx.doi.org/10.1016/S0960-894X(00)80300-5
CHEMBL1204685	14596	None	0	Guinea pig	Binding	IC50	=	0.50	9.30	-	1	Inhibition of [3H]LTD4 binding to guinea-pig lung membrane	ChEMBL	525.2	13	2	4	8.28	CC(CC[C@H](SCCCC(C)(C)O)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1)CC(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80300-5
CHEMBL1204687	14597	None	0	Guinea pig	Binding	IC50	=	1.40	8.85	-	1	Inhibition of [3H]LTD4 binding to guinea-pig lung membrane	ChEMBL	587.2	13	2	4	8.91	CC(C)(O)c1ccccc1CS[C@@H](CCC1(CC(=O)O)CC1)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1	https://dx.doi.org/10.1016/S0960-894X(00)80300-5
CHEMBL1204688	14598	None	0	Guinea pig	Binding	IC50	=	1.90	8.72	-	1	Inhibition of [3H]LTD4 binding to guinea-pig lung membrane	ChEMBL	589.2	13	2	4	9.16	CC(C)(CC[C@@H](SCc1ccccc1C(C)(C)O)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1)CC(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80300-5
CHEMBL1204689	14599	None	0	Guinea pig	Binding	IC50	=	0.60	9.22	-	1	Inhibition of [3H]LTD4 binding to guinea-pig lung membrane	ChEMBL	589.2	13	2	4	9.16	CC(C)(CC[C@H](SCc1ccccc1C(C)(C)O)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1)CC(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80300-5
CHEMBL1204690	14600	None	0	Guinea pig	Binding	IC50	=	1.00	9.00	-	1	Inhibition of [3H]LTD4 binding to guinea-pig lung membrane	ChEMBL	587.2	12	2	4	9.54	CC(C)(CC[C@@H](SCc1ccccc1C(C)(C)O)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1)CC(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80300-5
CHEMBL1204691	14601	None	0	Guinea pig	Binding	IC50	=	0.36	9.44	-	1	Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined	ChEMBL	558.1	12	2	6	7.13	O=C(O)CCSC(CCc1ccccc1-c1nc[nH]n1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1	https://dx.doi.org/10.1016/S0960-894X(00)80635-6
CHEMBL1204692	14602	None	0	Guinea pig	Binding	IC50	=	0.85	9.07	-	1	Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2	ChEMBL	563.2	12	2	5	7.82	CC(CSC(CCc1ccccc1C(C)(C)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80635-6
CHEMBL1204692	14602	None	0	Guinea pig	Binding	IC50	=	0.50	9.30	-	1	Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1	ChEMBL	563.2	12	2	5	7.82	CC(CSC(CCc1ccccc1C(C)(C)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80635-6
CHEMBL1204693	14603	None	0	Guinea pig	Binding	IC50	=	0.47	9.33	-	1	Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined	ChEMBL	562.2	13	2	5	7.08	CCC(CSC(CCc1ccccc1C(N)=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80635-6
CHEMBL1204694	14604	None	0	Guinea pig	Binding	IC50	=	0.60	9.22	-	1	Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2	ChEMBL	570.1	12	2	6	6.00	NS(=O)(=O)c1ccccc1CCC(SCCC(=O)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1	https://dx.doi.org/10.1016/S0960-894X(00)80635-6
CHEMBL1204694	14604	None	0	Guinea pig	Binding	IC50	=	0.40	9.40	-	1	Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1	ChEMBL	570.1	12	2	6	6.00	NS(=O)(=O)c1ccccc1CCC(SCCC(=O)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1	https://dx.doi.org/10.1016/S0960-894X(00)80635-6
CHEMBL1204695	14605	None	0	Guinea pig	Binding	IC50	=	4.00	8.40	-	1	Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2	ChEMBL	563.2	12	2	5	7.82	C[C@H](CS[C@H](CCc1ccccc1C(C)(C)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80635-6
CHEMBL1204695	14605	None	0	Guinea pig	Binding	IC50	=	2.00	8.70	-	1	Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1	ChEMBL	563.2	12	2	5	7.82	C[C@H](CS[C@H](CCc1ccccc1C(C)(C)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O	https://dx.doi.org/10.1016/S0960-894X(00)80635-6

Showing 1 to 20 of 636 entries

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

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Ligand source activities (1 row/activity)