GPCRdb

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

CHEMBL1206088	14701	None	0	Rat	Binding	EC50	=	692.00	6.16	-	1	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	472.2	17	2	4	6.05	CCCCCCCCc1ccc(CCCCCCC2OCC(COP(O)(O)=S)O2)cc1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1206091	14702	None	0	Rat	Binding	Ki	=	171.00	6.77	-	1	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	456.3	17	2	4	5.93	CCCCCCCCc1ccc(CCCCCCC2OCC(COP(=O)(O)O)O2)cc1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1206091	14702	None	0	Rat	Binding	IC50	=	504.00	6.30	-	1	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	456.3	17	2	4	5.93	CCCCCCCCc1ccc(CCCCCCC2OCC(COP(=O)(O)O)O2)cc1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1206092	14703	None	0	Rat	Binding	EC50	=	194.00	6.71	-	2	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	436.2	18	2	4	5.99	CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(O)(O)=S)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1206093	14704	None	0	Rat	Binding	EC50	=	639.00	6.19	-	2	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	436.2	18	2	4	5.99	CCCCCCC/C=C/CCCCCCCCC1OCC(COP(O)(O)=S)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1206094	14705	None	0	Rat	Binding	EC50	=	204.00	6.69	-	2	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	436.2	18	2	4	5.99	CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(O)(O)=S)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1207238	14821	None	0	Rat	Binding	IC50	=	209.00	6.68	-	1	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	420.3	18	2	4	5.88	CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(=O)(O)O)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1207238	14821	None	0	Rat	Binding	Ki	=	77.00	7.11	-	1	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	420.3	18	2	4	5.88	CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(=O)(O)O)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1207267	14826	None	0	Rat	Binding	IC50	=	484.00	6.32	-	1	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	420.3	18	2	4	5.88	CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(=O)(O)O)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1207267	14826	None	0	Rat	Binding	Ki	=	241.00	6.62	-	1	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	420.3	18	2	4	5.88	CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(=O)(O)O)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1207268	14827	None	0	Rat	Binding	EC50	=	7590.00	5.12	-	2	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	416.2	16	2	4	5.43	C/C=C/C/C=C/C/C=C/CCCCCCCCC1OCC(COP(=O)(O)O)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1207662	14880	None	0	Rat	Binding	EC50	=	265.00	6.58	-	2	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	436.2	18	2	4	5.99	CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(O)(O)=S)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1207670	14881	None	0	Rat	Binding	EC50	=	127.00	6.90	-	2	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	436.2	18	2	4	5.99	CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@H](COP(O)(O)=S)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1207755	14888	None	0	Rat	Binding	IC50	=	136.00	6.87	-	2	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	420.3	18	2	4	5.88	CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(=O)(O)O)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL1207755	14888	None	0	Rat	Binding	Ki	=	83.00	7.08	-	2	Activity at LPA3 receptor in RH7777 rat hepatoma cell line	ChEMBL	420.3	18	2	4	5.88	CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(=O)(O)O)O1	https://dx.doi.org/10.1016/j.bmcl.2005.08.096
CHEMBL153043	45745	None	0	Human	Binding	EC50	=	0.44	9.36	-	6	Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay	ChEMBL	468.3	22	2	5	6.03	CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC	https://dx.doi.org/10.1016/j.bmcl.2013.01.002
CHEMBL153043	45745	None	0	Human	Binding	EC50	=	0.45	9.35	-	6	Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay	ChEMBL	468.3	22	2	5	6.03	CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC	https://dx.doi.org/10.1016/j.bmcl.2013.01.002
CHEMBL181612	64603	None	0	Human	Binding	Ki	=	232.00	6.63	-	2	Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor	ChEMBL	615.4	24	4	4	8.22	CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)CC(O)P(=O)(O)O	https://dx.doi.org/10.1016/j.bmcl.2004.05.023
CHEMBL181917	64787	None	0	Human	Binding	Ki	=	561.00	6.25	-	2	Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor	ChEMBL	660.4	25	3	6	8.46	CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.05.023
CHEMBL182302	65014	None	0	Human	Binding	Ki	=	2600.00	5.58	-	1	Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor	ChEMBL	682.4	25	3	6	9.00	CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OC)c3ccccc3n2)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.05.023

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Ligand source activities (1 row/activity)