Ligand source activities (1 row/activity)
Ligands | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID | #Vendors | Reference ligand |
Fold selectivity (Potency) |
# tested GPCRs (Potency) |
Species | p-value (-log) |
Type | Activity Relation |
Activity Value |
Assay Type | Assay Description | Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI |
5311263 | 10929 | 22 | None | -29 | 7 | Human | 6.9 | pEC50 | = | 6.9 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmc.2009.12.020 | ||
CHEMBL117021 | 10929 | 22 | None | -29 | 7 | Human | 6.9 | pEC50 | = | 6.9 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmc.2009.12.020 | ||
6610239 | 74389 | 27 | None | 1 | 2 | Human | 5.8 | pEC50 | = | 5.8 | Functional | ChEMBL | 423 | 19 | 4 | 4 | 4.1 | CCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)(O)O)C(=O)O | 10.1021/jm049609r | ||
CHEMBL190328 | 74389 | 27 | None | 1 | 2 | Human | 5.8 | pEC50 | = | 5.8 | Functional | ChEMBL | 423 | 19 | 4 | 4 | 4.1 | CCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)(O)O)C(=O)O | 10.1021/jm049609r | ||
5311263 | 10929 | 22 | None | -29 | 7 | Human | 6.6 | pEC50 | = | 6.6 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2004.04.061 | ||
CHEMBL117021 | 10929 | 22 | None | -29 | 7 | Human | 6.6 | pEC50 | = | 6.6 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2004.04.061 | ||
2906 | 9134 | 18 | None | -36 | 12 | Human | 6.5 | pEC50 | = | 6.5 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
5395 | 9134 | 18 | None | -36 | 12 | Human | 6.5 | pEC50 | = | 6.5 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
5497152 | 9134 | 18 | None | -36 | 12 | Human | 6.5 | pEC50 | = | 6.5 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
CHEMBL1222042 | 9134 | 18 | None | -36 | 12 | Human | 6.5 | pEC50 | = | 6.5 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
11473989 | 73895 | 0 | None | -2 | 3 | Human | 6.3 | pEC50 | = | 6.3 | Functional | ChEMBL | 364 | 17 | 2 | 2 | 6.3 | CCCCCCCC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL187459 | 73895 | 0 | None | -2 | 3 | Human | 6.3 | pEC50 | = | 6.3 | Functional | ChEMBL | 364 | 17 | 2 | 2 | 6.3 | CCCCCCCC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
122191543 | 130479 | 0 | None | 12 | 2 | Human | 7.2 | pEC50 | = | 7.2 | Functional | ChEMBL | 452 | 22 | 2 | 4 | 6.3 | CCCCCCCC/C=C\CCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1039/C4MD00333K | ||
CHEMBL3621961 | 130479 | 0 | None | 12 | 2 | Human | 7.2 | pEC50 | = | 7.2 | Functional | ChEMBL | 452 | 22 | 2 | 4 | 6.3 | CCCCCCCC/C=C\CCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1039/C4MD00333K | ||
2913 | 7135 | 0 | None | 8 | 2 | Human | 7.1 | pEC50 | = | 7.1 | Functional | ChEMBL | 452 | 22 | 2 | 4 | 6.3 | CCCCCCCC/C=C\CCCCCCCCOC[C@@H](COP(=S)(O)O)OC | 10.1039/C4MD00333K | ||
56947064 | 7135 | 0 | None | 8 | 2 | Human | 7.1 | pEC50 | = | 7.1 | Functional | ChEMBL | 452 | 22 | 2 | 4 | 6.3 | CCCCCCCC/C=C\CCCCCCCCOC[C@@H](COP(=S)(O)O)OC | 10.1039/C4MD00333K | ||
CHEMBL3621962 | 7135 | 0 | None | 8 | 2 | Human | 7.1 | pEC50 | = | 7.1 | Functional | ChEMBL | 452 | 22 | 2 | 4 | 6.3 | CCCCCCCC/C=C\CCCCCCCCOC[C@@H](COP(=S)(O)O)OC | 10.1039/C4MD00333K | ||
5311263 | 10929 | 22 | None | -29 | 7 | Human | 6.1 | pEC50 | = | 6.1 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1021/jm5007116 | ||
CHEMBL117021 | 10929 | 22 | None | -29 | 7 | Human | 6.1 | pEC50 | = | 6.1 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1021/jm5007116 | ||
11312382 | 74131 | 1 | None | 21 | 3 | Human | 7.0 | pIC50 | = | 7.0 | Functional | ChEMBL | 292 | 13 | 2 | 2 | 4.6 | CC/C=C/CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL188591 | 74131 | 1 | None | 21 | 3 | Human | 7.0 | pIC50 | = | 7.0 | Functional | ChEMBL | 292 | 13 | 2 | 2 | 4.6 | CC/C=C/CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
122191544 | 130481 | 0 | None | -4 | 4 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 484 | 18 | 3 | 4 | 5.4 | CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00333K | ||
CHEMBL3621964 | 130481 | 0 | None | -4 | 4 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 484 | 18 | 3 | 4 | 5.4 | CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00333K | ||
81309 | 74035 | 68 | None | - | 1 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 222 | 9 | 2 | 1 | 3.3 | CCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
88299705 | 74035 | 68 | None | - | 1 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 222 | 9 | 2 | 1 | 3.3 | CCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL188083 | 74035 | 68 | None | - | 1 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 222 | 9 | 2 | 1 | 3.3 | CCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
44454369 | 162393 | 0 | None | -239 | 2 | Human | 4.9 | pIC50 | = | 4.9 | Functional | ChEMBL | 322 | 4 | 1 | 4 | 5.0 | Cc1noc(-c2ccccc2)c1NC(=O)OC(C)c1ccccc1 | 10.1016/j.bmcl.2007.12.024 | ||
CHEMBL404575 | 162393 | 0 | None | -239 | 2 | Human | 4.9 | pIC50 | = | 4.9 | Functional | ChEMBL | 322 | 4 | 1 | 4 | 5.0 | Cc1noc(-c2ccccc2)c1NC(=O)OC(C)c1ccccc1 | 10.1016/j.bmcl.2007.12.024 | ||
11242245 | 73972 | 5 | None | 37 | 2 | Human | 6.9 | pIC50 | = | 6.9 | Functional | ChEMBL | 254 | 10 | 2 | 2 | 3.4 | CCCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL187795 | 73972 | 5 | None | 37 | 2 | Human | 6.9 | pIC50 | = | 6.9 | Functional | ChEMBL | 254 | 10 | 2 | 2 | 3.4 | CCCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
2260227 | 190866 | 10 | None | -138 | 3 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 488 | 10 | 4 | 6 | 4.4 | O=C(O)/C=C/C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)/C=C/C(=O)O)cc3)c2)cc1 | 10.1016/j.bmc.2008.04.035 | ||
CHEMBL482498 | 190866 | 10 | None | -138 | 3 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 488 | 10 | 4 | 6 | 4.4 | O=C(O)/C=C/C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)/C=C/C(=O)O)cc3)c2)cc1 | 10.1016/j.bmc.2008.04.035 | ||
2260227 | 190866 | 10 | None | -138 | 3 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 488 | 10 | 4 | 6 | 4.4 | O=C(O)/C=C/C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)/C=C/C(=O)O)cc3)c2)cc1 | 10.1016/j.bmc.2009.09.022 | ||
CHEMBL482498 | 190866 | 10 | None | -138 | 3 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 488 | 10 | 4 | 6 | 4.4 | O=C(O)/C=C/C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)/C=C/C(=O)O)cc3)c2)cc1 | 10.1016/j.bmc.2009.09.022 | ||
16043259 | 86584 | 0 | None | -1 | 2 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 434 | 18 | 1 | 4 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 | 10.1021/jm060351+ | ||
CHEMBL212029 | 86584 | 0 | None | -1 | 2 | Human | 5.9 | pIC50 | = | 5.9 | Functional | ChEMBL | 434 | 18 | 1 | 4 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 | 10.1021/jm060351+ | ||
71457480 | 89903 | 0 | None | -2 | 2 | Human | 6.9 | pIC50 | = | 6.9 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
CHEMBL2182046 | 89903 | 0 | None | -2 | 2 | Human | 6.9 | pIC50 | = | 6.9 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
71457480 | 89903 | 0 | None | -2 | 2 | Human | 6.9 | pIC50 | = | 6.9 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | nan | ||
CHEMBL2182046 | 89903 | 0 | None | -2 | 2 | Human | 6.9 | pIC50 | = | 6.9 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | nan | ||
1105689 | 190865 | 38 | None | -489 | 2 | Human | 4.9 | pIC50 | = | 4.9 | Functional | ChEMBL | 380 | 7 | 4 | 4 | 2.5 | O=C(O)/C=C/C(=O)Nc1ccc(-c2ccc(NC(=O)/C=C/C(=O)O)cc2)cc1 | 10.1016/j.bmc.2008.04.035 | ||
CHEMBL482497 | 190865 | 38 | None | -489 | 2 | Human | 4.9 | pIC50 | = | 4.9 | Functional | ChEMBL | 380 | 7 | 4 | 4 | 2.5 | O=C(O)/C=C/C(=O)Nc1ccc(-c2ccc(NC(=O)/C=C/C(=O)O)cc2)cc1 | 10.1016/j.bmc.2008.04.035 | ||
11393306 | 74189 | 1 | None | 1 | 2 | Human | 5.8 | pIC50 | = | 5.8 | Functional | ChEMBL | 328 | 14 | 2 | 1 | 5.8 | CCCCCCCCCCCCCCC(F)(F)P(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL188859 | 74189 | 1 | None | 1 | 2 | Human | 5.8 | pIC50 | = | 5.8 | Functional | ChEMBL | 328 | 14 | 2 | 1 | 5.8 | CCCCCCCCCCCCCCC(F)(F)P(=O)(O)O | 10.1021/jm049609r | ||
10367662 | 8967 | 91 | None | -4 | 5 | Human | 5.8 | pIC50 | = | 5.8 | Functional | ChEMBL | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 10.1021/acs.jmedchem.2c00046 | ||
2907 | 8967 | 91 | None | -4 | 5 | Human | 5.8 | pIC50 | = | 5.8 | Functional | ChEMBL | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 10.1021/acs.jmedchem.2c00046 | ||
CHEMBL361501 | 8967 | 91 | None | -4 | 5 | Human | 5.8 | pIC50 | = | 5.8 | Functional | ChEMBL | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 10.1021/acs.jmedchem.2c00046 | ||
2905 | 7177 | 49 | None | -89 | 7 | Human | 5.8 | pIC50 | = | 5.8 | Functional | ChEMBL | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 10.1039/C4MD00333K | ||
46240292 | 7177 | 49 | None | -89 | 7 | Human | 5.8 | pIC50 | = | 5.8 | Functional | ChEMBL | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 10.1039/C4MD00333K | ||
CHEMBL3621966 | 7177 | 49 | None | -89 | 7 | Human | 5.8 | pIC50 | = | 5.8 | Functional | ChEMBL | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 10.1039/C4MD00333K | ||
11312936 | 74260 | 0 | None | 15 | 2 | Human | 6.8 | pIC50 | = | 6.8 | Functional | ChEMBL | 310 | 14 | 2 | 2 | 4.9 | CCCCCCCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL189296 | 74260 | 0 | None | 15 | 2 | Human | 6.8 | pIC50 | = | 6.8 | Functional | ChEMBL | 310 | 14 | 2 | 2 | 4.9 | CCCCCCCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
10393842 | 175978 | 0 | None | -1 | 2 | Human | 6.8 | pIC50 | = | 6.8 | Functional | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL440696 | 175978 | 0 | None | -1 | 2 | Human | 6.8 | pIC50 | = | 6.8 | Functional | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
72704618 | 166694 | 0 | None | -4 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 482 | 7 | 2 | 6 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3cccc(C4(C(=O)O)CC4)c3)cc2)nnn1C)c1ccccc1 | nan | ||
CHEMBL4107074 | 166694 | 0 | None | -4 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 482 | 7 | 2 | 6 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3cccc(C4(C(=O)O)CC4)c3)cc2)nnn1C)c1ccccc1 | nan | ||
71457482 | 89907 | 0 | None | -165 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 462 | 7 | 2 | 6 | 5.5 | C[C@@H](OC(=O)Nc1c(-c2ccc(C3CCC(CC(=O)O)CC3)cc2)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
CHEMBL2182051 | 89907 | 0 | None | -165 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 462 | 7 | 2 | 6 | 5.5 | C[C@@H](OC(=O)Nc1c(-c2ccc(C3CCC(CC(=O)O)CC3)cc2)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
71457482 | 89907 | 0 | None | -165 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 462 | 7 | 2 | 6 | 5.5 | C[C@@H](OC(=O)Nc1c(-c2ccc(C3CCC(CC(=O)O)CC3)cc2)nnn1C)c1ccccc1 | nan | ||
CHEMBL2182051 | 89907 | 0 | None | -165 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 462 | 7 | 2 | 6 | 5.5 | C[C@@H](OC(=O)Nc1c(-c2ccc(C3CCC(CC(=O)O)CC3)cc2)nnn1C)c1ccccc1 | nan | ||
71453960 | 89899 | 0 | None | -162 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 456 | 7 | 2 | 6 | 5.1 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(CC(=O)O)cc3)cc2)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
CHEMBL2182042 | 89899 | 0 | None | -162 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 456 | 7 | 2 | 6 | 5.1 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(CC(=O)O)cc3)cc2)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
71453960 | 89899 | 0 | None | -162 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 456 | 7 | 2 | 6 | 5.1 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(CC(=O)O)cc3)cc2)nnn1C)c1ccccc1 | nan | ||
CHEMBL2182042 | 89899 | 0 | None | -162 | 2 | Human | 4.7 | pIC50 | = | 4.7 | Functional | ChEMBL | 456 | 7 | 2 | 6 | 5.1 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(CC(=O)O)cc3)cc2)nnn1C)c1ccccc1 | nan | ||
70856266 | 89900 | 0 | None | -120 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 482 | 7 | 2 | 6 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
CHEMBL2182043 | 89900 | 0 | None | -120 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 482 | 7 | 2 | 6 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
70856266 | 89900 | 0 | None | -120 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 482 | 7 | 2 | 6 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1ccccc1 | nan | ||
CHEMBL2182043 | 89900 | 0 | None | -120 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 482 | 7 | 2 | 6 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1ccccc1 | nan | ||
122191545 | 130482 | 0 | None | -17 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 446 | 8 | 2 | 6 | 5.6 | CC(OC(=O)Nc1cnoc1-c1ccc(CSCC(=O)O)cc1)c1ccccc1Cl | 10.1039/C4MD00333K | ||
CHEMBL3621965 | 130482 | 0 | None | -17 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 446 | 8 | 2 | 6 | 5.6 | CC(OC(=O)Nc1cnoc1-c1ccc(CSCC(=O)O)cc1)c1ccccc1Cl | 10.1039/C4MD00333K | ||
71452129 | 89905 | 0 | None | -120 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 559 | 8 | 2 | 8 | 4.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
CHEMBL2182049 | 89905 | 0 | None | -120 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 559 | 8 | 2 | 8 | 4.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
71452129 | 89905 | 0 | None | -120 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 559 | 8 | 2 | 8 | 4.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1ccccc1 | nan | ||
CHEMBL2182049 | 89905 | 0 | None | -120 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 559 | 8 | 2 | 8 | 4.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1ccccc1 | nan | ||
44325401 | 112895 | 0 | None | 1 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 627 | 23 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OC2Cc3ccccc3C2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL313413 | 112895 | 0 | None | 1 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 627 | 23 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OC2Cc3ccccc3C2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
11849496 | 86381 | 0 | None | -2 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 406 | 16 | 1 | 4 | 6.1 | CCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 | 10.1021/jm060351+ | ||
CHEMBL211465 | 86381 | 0 | None | -2 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 406 | 16 | 1 | 4 | 6.1 | CCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 | 10.1021/jm060351+ | ||
CHEMBL2372286 | 216989 | 1 | None | - | 1 | Human | 7.6 | pIC50 | = | 7.6 | Functional | ChEMBL | None | None | None | NCC(=O)N[C@@H](CSc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)N[C@@H](CCC(=O)O)C(=O)O | 10.1016/j.bmc.2008.04.035 | ||||
CHEMBL2372286 | 216989 | 1 | None | - | 1 | Human | 7.6 | pIC50 | = | 7.6 | Functional | ChEMBL | None | None | None | NCC(=O)N[C@@H](CSc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)N[C@@H](CCC(=O)O)C(=O)O | 10.1016/j.bmc.2009.09.022 | ||||
44325681 | 113672 | 0 | None | 2 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 626 | 23 | 4 | 4 | 9.1 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(Oc2cc3ccccc3[nH]2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL314554 | 113672 | 0 | None | 2 | 2 | Human | 5.6 | pIC50 | = | 5.6 | Functional | ChEMBL | 626 | 23 | 4 | 4 | 9.1 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(Oc2cc3ccccc3[nH]2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
11208266 | 74406 | 1 | None | 25 | 2 | Human | 7.6 | pIC50 | = | 7.6 | Functional | ChEMBL | 280 | 11 | 2 | 2 | 3.9 | CC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL190484 | 74406 | 1 | None | 25 | 2 | Human | 7.6 | pIC50 | = | 7.6 | Functional | ChEMBL | 280 | 11 | 2 | 2 | 3.9 | CC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
71455703 | 89901 | 0 | None | -1445 | 2 | Human | 4.6 | pIC50 | = | 4.6 | Functional | ChEMBL | 500 | 7 | 2 | 6 | 5.7 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2F)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
CHEMBL2182044 | 89901 | 0 | None | -1445 | 2 | Human | 4.6 | pIC50 | = | 4.6 | Functional | ChEMBL | 500 | 7 | 2 | 6 | 5.7 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2F)nnn1C)c1ccccc1 | 10.1021/jm301022v | ||
71455703 | 89901 | 0 | None | -1445 | 2 | Human | 4.6 | pIC50 | = | 4.6 | Functional | ChEMBL | 500 | 7 | 2 | 6 | 5.7 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2F)nnn1C)c1ccccc1 | nan | ||
CHEMBL2182044 | 89901 | 0 | None | -1445 | 2 | Human | 4.6 | pIC50 | = | 4.6 | Functional | ChEMBL | 500 | 7 | 2 | 6 | 5.7 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2F)nnn1C)c1ccccc1 | nan | ||
72704617 | 159030 | 0 | None | -6 | 2 | Human | 6.6 | pIC50 | = | 6.6 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | CC(OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | nan | ||
CHEMBL3969018 | 159030 | 0 | None | -6 | 2 | Human | 6.6 | pIC50 | = | 6.6 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | CC(OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | nan | ||
10468943 | 8239 | 5 | None | 35 | 3 | Human | 7.6 | pIC50 | = | 7.6 | Functional | ChEMBL | 282 | 12 | 2 | 2 | 4.1 | CCCCCCCCCCCCOP(=S)(O)O | 10.1021/jm049609r | ||
6990 | 8239 | 5 | None | 35 | 3 | Human | 7.6 | pIC50 | = | 7.6 | Functional | ChEMBL | 282 | 12 | 2 | 2 | 4.1 | CCCCCCCCCCCCOP(=S)(O)O | 10.1021/jm049609r | ||
CHEMBL191365 | 8239 | 5 | None | 35 | 3 | Human | 7.6 | pIC50 | = | 7.6 | Functional | ChEMBL | 282 | 12 | 2 | 2 | 4.1 | CCCCCCCCCCCCOP(=S)(O)O | 10.1021/jm049609r | ||
11220562 | 73883 | 0 | None | 16 | 2 | Human | 7.6 | pIC50 | = | 7.6 | Functional | ChEMBL | 308 | 13 | 2 | 2 | 4.7 | CCCC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL187402 | 73883 | 0 | None | 16 | 2 | Human | 7.6 | pIC50 | = | 7.6 | Functional | ChEMBL | 308 | 13 | 2 | 2 | 4.7 | CCCC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
753410 | 208735 | 10 | None | -4 | 2 | Human | 5.5 | pIC50 | = | 5.5 | Functional | ChEMBL | 311 | 4 | 1 | 4 | 2.5 | Cc1ccc(Oc2ccc3c(c2)C(=O)N(CC(=O)O)C3=O)cc1 | 10.1016/j.bmc.2009.09.022 | ||
CHEMBL607806 | 208735 | 10 | None | -4 | 2 | Human | 5.5 | pIC50 | = | 5.5 | Functional | ChEMBL | 311 | 4 | 1 | 4 | 2.5 | Cc1ccc(Oc2ccc3c(c2)C(=O)N(CC(=O)O)C3=O)cc1 | 10.1016/j.bmc.2009.09.022 | ||
5861754 | 191547 | 2 | None | 11 | 2 | Human | 7.5 | pIC50 | = | 7.5 | Functional | ChEMBL | 348 | 7 | 5 | 5 | 0.5 | O=C(O)/C=C/C(=O)Nc1cccc(NC(=O)/C=C/C(=O)O)c1C(=O)O | 10.1016/j.bmc.2008.04.035 | ||
CHEMBL485119 | 191547 | 2 | None | 11 | 2 | Human | 7.5 | pIC50 | = | 7.5 | Functional | ChEMBL | 348 | 7 | 5 | 5 | 0.5 | O=C(O)/C=C/C(=O)Nc1cccc(NC(=O)/C=C/C(=O)O)c1C(=O)O | 10.1016/j.bmc.2008.04.035 | ||
5861754 | 191547 | 2 | None | 11 | 2 | Human | 7.5 | pIC50 | = | 7.5 | Functional | ChEMBL | 348 | 7 | 5 | 5 | 0.5 | O=C(O)/C=C/C(=O)Nc1cccc(NC(=O)/C=C/C(=O)O)c1C(=O)O | 10.1016/j.bmc.2009.09.022 | ||
CHEMBL485119 | 191547 | 2 | None | 11 | 2 | Human | 7.5 | pIC50 | = | 7.5 | Functional | ChEMBL | 348 | 7 | 5 | 5 | 0.5 | O=C(O)/C=C/C(=O)Nc1cccc(NC(=O)/C=C/C(=O)O)c1C(=O)O | 10.1016/j.bmc.2009.09.022 | ||
10367662 | 8967 | 91 | None | -4 | 5 | Human | 6.5 | pIC50 | = | 6.5 | Functional | ChEMBL | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 10.1021/jm049609r | ||
2907 | 8967 | 91 | None | -4 | 5 | Human | 6.5 | pIC50 | = | 6.5 | Functional | ChEMBL | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 10.1021/jm049609r | ||
CHEMBL361501 | 8967 | 91 | None | -4 | 5 | Human | 6.5 | pIC50 | = | 6.5 | Functional | ChEMBL | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 10.1021/jm049609r | ||
78401 | 74622 | 60 | None | 1 | 2 | Human | 5.5 | pIC50 | = | 5.5 | Functional | ChEMBL | 278 | 13 | 2 | 1 | 4.9 | CCCCCCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL190999 | 74622 | 60 | None | 1 | 2 | Human | 5.5 | pIC50 | = | 5.5 | Functional | ChEMBL | 278 | 13 | 2 | 1 | 4.9 | CCCCCCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
11219269 | 74391 | 1 | None | 22 | 2 | Human | 7.5 | pIC50 | = | 7.5 | Functional | ChEMBL | 264 | 11 | 2 | 2 | 3.8 | CC/C=C/CCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL190349 | 74391 | 1 | None | 22 | 2 | Human | 7.5 | pIC50 | = | 7.5 | Functional | ChEMBL | 264 | 11 | 2 | 2 | 3.8 | CC/C=C/CCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
44325366 | 214204 | 0 | None | - | 1 | Human | 5.5 | pIC50 | = | 5.5 | Functional | ChEMBL | 591 | 26 | 3 | 4 | 8.0 | C#CCCCCOc1ccc(C[C@H](COP(=O)(O)O)NC(=O)CCCCCCC/C=C\CCCCCCCC)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL94034 | 214204 | 0 | None | - | 1 | Human | 5.5 | pIC50 | = | 5.5 | Functional | ChEMBL | 591 | 26 | 3 | 4 | 8.0 | C#CCCCCOc1ccc(C[C@H](COP(=O)(O)O)NC(=O)CCCCCCC/C=C\CCCCCCCC)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
11288209 | 131168 | 2 | None | - | 1 | Human | 6.5 | pIC50 | = | 6.5 | Functional | ChEMBL | 252 | 10 | 2 | 2 | 3.1 | C=CCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL363935 | 131168 | 2 | None | - | 1 | Human | 6.5 | pIC50 | = | 6.5 | Functional | ChEMBL | 252 | 10 | 2 | 2 | 3.1 | C=CCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
2230607 | 103175 | 4 | None | - | 1 | Human | 6.5 | pIC50 | = | 6.5 | Functional | ChEMBL | 310 | 5 | 3 | 3 | 2.5 | O=C(O)/C=C\C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 | 10.1016/j.bmc.2008.04.035 | ||
CHEMBL261872 | 103175 | 4 | None | - | 1 | Human | 6.5 | pIC50 | = | 6.5 | Functional | ChEMBL | 310 | 5 | 3 | 3 | 2.5 | O=C(O)/C=C\C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 | 10.1016/j.bmc.2008.04.035 | ||
44325391 | 213708 | 0 | None | 30 | 2 | Human | 7.5 | pIC50 | = | 7.5 | Functional | ChEMBL | 631 | 25 | 3 | 5 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)c2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL91058 | 213708 | 0 | None | 30 | 2 | Human | 7.5 | pIC50 | = | 7.5 | Functional | ChEMBL | 631 | 25 | 3 | 5 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)c2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
44325365 | 119129 | 0 | None | - | 1 | Human | 6.5 | pIC50 | = | 6.5 | Functional | ChEMBL | 581 | 25 | 3 | 4 | 8.3 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCCC(C)C)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL329422 | 119129 | 0 | None | - | 1 | Human | 6.5 | pIC50 | = | 6.5 | Functional | ChEMBL | 581 | 25 | 3 | 4 | 8.3 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCCC(C)C)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
4030 | 8140 | 19 | None | 6 | 2 | Human | 6.4 | pIC50 | = | 6.4 | Functional | ChEMBL | 238 | 10 | 2 | 2 | 3.2 | CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
62532 | 8140 | 19 | None | 6 | 2 | Human | 6.4 | pIC50 | = | 6.4 | Functional | ChEMBL | 238 | 10 | 2 | 2 | 3.2 | CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL361255 | 8140 | 19 | None | 6 | 2 | Human | 6.4 | pIC50 | = | 6.4 | Functional | ChEMBL | 238 | 10 | 2 | 2 | 3.2 | CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
75816 | 73947 | 53 | None | 7 | 3 | Human | 6.4 | pIC50 | = | 6.4 | Functional | ChEMBL | 266 | 12 | 2 | 2 | 4.0 | CCCCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL187711 | 73947 | 53 | None | 7 | 3 | Human | 6.4 | pIC50 | = | 6.4 | Functional | ChEMBL | 266 | 12 | 2 | 2 | 4.0 | CCCCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
9958483 | 104613 | 0 | None | 2 | 2 | Human | 7.4 | pIC50 | = | 7.4 | Functional | ChEMBL | 525 | 12 | 1 | 5 | 6.5 | COc1cc(OC)cc(C(=O)N(CCCc2ccccc2)Cc2ccc(Oc3ccccc3C(=O)O)cc2)c1 | 10.1016/j.bmcl.2007.12.024 | ||
CHEMBL272087 | 104613 | 0 | None | 2 | 2 | Human | 7.4 | pIC50 | = | 7.4 | Functional | ChEMBL | 525 | 12 | 1 | 5 | 6.5 | COc1cc(OC)cc(C(=O)N(CCCc2ccccc2)Cc2ccc(Oc3ccccc3C(=O)O)cc2)c1 | 10.1016/j.bmcl.2007.12.024 | ||
44325390 | 119120 | 0 | None | - | 1 | Human | 5.4 | pIC50 | = | 5.4 | Functional | ChEMBL | 607 | 24 | 3 | 4 | 8.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCC2CCCCC2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL329378 | 119120 | 0 | None | - | 1 | Human | 5.4 | pIC50 | = | 5.4 | Functional | ChEMBL | 607 | 24 | 3 | 4 | 8.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCC2CCCCC2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
82327 | 73933 | 14 | None | 5 | 2 | Human | 6.4 | pIC50 | = | 6.4 | Functional | ChEMBL | 294 | 14 | 2 | 2 | 4.8 | CCCCCCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL187633 | 73933 | 14 | None | 5 | 2 | Human | 6.4 | pIC50 | = | 6.4 | Functional | ChEMBL | 294 | 14 | 2 | 2 | 4.8 | CCCCCCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
44325400 | 112894 | 0 | None | - | 1 | Human | 6.4 | pIC50 | = | 6.4 | Functional | ChEMBL | 705 | 26 | 3 | 8 | 8.1 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OC(=O)c2cc(OC)c(OC)c(OC)c2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL313412 | 112894 | 0 | None | - | 1 | Human | 6.4 | pIC50 | = | 6.4 | Functional | ChEMBL | 705 | 26 | 3 | 8 | 8.1 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OC(=O)c2cc(OC)c(OC)c(OC)c2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
869604 | 209068 | 10 | None | - | 1 | Human | 5.4 | pIC50 | = | 5.4 | Functional | ChEMBL | 342 | 5 | 1 | 6 | 2.1 | O=C(O)CN1C(=O)c2ccc(Oc3cccc([N+](=O)[O-])c3)cc2C1=O | 10.1016/j.bmc.2009.09.022 | ||
CHEMBL610179 | 209068 | 10 | None | - | 1 | Human | 5.4 | pIC50 | = | 5.4 | Functional | ChEMBL | 342 | 5 | 1 | 6 | 2.1 | O=C(O)CN1C(=O)c2ccc(Oc3cccc([N+](=O)[O-])c3)cc2C1=O | 10.1016/j.bmc.2009.09.022 | ||
10051843 | 8211 | 2 | None | 24 | 2 | Human | 6.3 | pIC50 | = | 6.3 | Functional | ChEMBL | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 10.1021/jm049609r | ||
2916 | 8211 | 2 | None | 24 | 2 | Human | 6.3 | pIC50 | = | 6.3 | Functional | ChEMBL | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 10.1021/jm049609r | ||
CHEMBL191055 | 8211 | 2 | None | 24 | 2 | Human | 6.3 | pIC50 | = | 6.3 | Functional | ChEMBL | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 10.1021/jm049609r | ||
71462858 | 89882 | 0 | None | -11 | 2 | Human | 6.3 | pIC50 | = | 6.3 | Functional | ChEMBL | 549 | 7 | 2 | 5 | 7.2 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)cnn1C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
CHEMBL2182023 | 89882 | 0 | None | -11 | 2 | Human | 6.3 | pIC50 | = | 6.3 | Functional | ChEMBL | 549 | 7 | 2 | 5 | 7.2 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)cnn1C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
11755685 | 74284 | 0 | None | - | 1 | Human | 5.3 | pIC50 | = | 5.3 | Functional | ChEMBL | 499 | 20 | 4 | 4 | 5.8 | CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(OP(=O)(O)O)cc1)C(=O)O | 10.1021/jm049609r | ||
CHEMBL189515 | 74284 | 0 | None | - | 1 | Human | 5.3 | pIC50 | = | 5.3 | Functional | ChEMBL | 499 | 20 | 4 | 4 | 5.8 | CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(OP(=O)(O)O)cc1)C(=O)O | 10.1021/jm049609r | ||
71452130 | 89915 | 0 | None | -239 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 499 | 7 | 2 | 5 | 6.3 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)cnn1C)c1ccccc1F | 10.1021/jm301022v | ||
CHEMBL2182064 | 89915 | 0 | None | -239 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 499 | 7 | 2 | 5 | 6.3 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)cnn1C)c1ccccc1F | 10.1021/jm301022v | ||
44325364 | 213979 | 0 | None | - | 1 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 581 | 25 | 3 | 4 | 8.3 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCCC(C)C)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL92593 | 213979 | 0 | None | - | 1 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 581 | 25 | 3 | 4 | 8.3 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCCC(C)C)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
71455704 | 89904 | 0 | None | -2 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | C[C@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
CHEMBL2182047 | 89904 | 0 | None | -2 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | C[C@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
71455704 | 89904 | 0 | None | -2 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | C[C@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | nan | ||
CHEMBL2182047 | 89904 | 0 | None | -2 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.6 | C[C@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | nan | ||
44325370 | 214212 | 0 | None | - | 1 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 539 | 23 | 3 | 4 | 7.3 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCC)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL94089 | 214212 | 0 | None | - | 1 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 539 | 23 | 3 | 4 | 7.3 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCC)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
11599847 | 213515 | 0 | None | 8 | 2 | Human | 6.2 | pIC50 | = | 6.2 | Functional | ChEMBL | 631 | 25 | 3 | 5 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)c2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL89937 | 213515 | 0 | None | 8 | 2 | Human | 6.2 | pIC50 | = | 6.2 | Functional | ChEMBL | 631 | 25 | 3 | 5 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)c2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
5311306 | 103322 | 2 | None | -1 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCc2ccccc2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL262906 | 103322 | 2 | None | -1 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCc2ccccc2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
71457481 | 89906 | 0 | None | -2 | 2 | Human | 7.2 | pIC50 | = | 7.2 | Functional | ChEMBL | 627 | 8 | 2 | 8 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
CHEMBL2182050 | 89906 | 0 | None | -2 | 2 | Human | 7.2 | pIC50 | = | 7.2 | Functional | ChEMBL | 627 | 8 | 2 | 8 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
71457481 | 89906 | 0 | None | -2 | 2 | Human | 7.2 | pIC50 | = | 7.2 | Functional | ChEMBL | 627 | 8 | 2 | 8 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | nan | ||
CHEMBL2182050 | 89906 | 0 | None | -2 | 2 | Human | 7.2 | pIC50 | = | 7.2 | Functional | ChEMBL | 627 | 8 | 2 | 8 | 5.6 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1cccc(C(F)(F)F)c1 | nan | ||
78816 | 130820 | 56 | None | - | 1 | Human | 6.2 | pIC50 | = | 6.2 | Functional | ChEMBL | 250 | 11 | 2 | 1 | 4.1 | CCCCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL363067 | 130820 | 56 | None | - | 1 | Human | 6.2 | pIC50 | = | 6.2 | Functional | ChEMBL | 250 | 11 | 2 | 1 | 4.1 | CCCCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
3114900 | 120376 | 57 | None | -1 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 391 | 6 | 1 | 4 | 4.3 | O=C(O)c1ccccc1SCCCN1C(=O)c2cccc3cccc(c23)C1=O | 10.1021/jm5007116 | ||
CHEMBL3322500 | 120376 | 57 | None | -1 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 391 | 6 | 1 | 4 | 4.3 | O=C(O)c1ccccc1SCCCN1C(=O)c2cccc3cccc(c23)C1=O | 10.1021/jm5007116 | ||
44325421 | 176016 | 0 | None | - | 1 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 575 | 23 | 3 | 4 | 7.9 | CCCCCCCCCCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCc2ccccc2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL441066 | 176016 | 0 | None | - | 1 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 575 | 23 | 3 | 4 | 7.9 | CCCCCCCCCCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCc2ccccc2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
71455702 | 89890 | 0 | None | -39 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.7 | Cc1nnn(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1NC(=O)O[C@H](C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
CHEMBL2182032 | 89890 | 0 | None | -39 | 2 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 550 | 7 | 2 | 6 | 6.7 | Cc1nnn(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1NC(=O)O[C@H](C)c1cccc(C(F)(F)F)c1 | 10.1021/jm301022v | ||
44325351 | 170182 | 0 | None | - | 1 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 539 | 23 | 3 | 4 | 7.3 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCC)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL419507 | 170182 | 0 | None | - | 1 | Human | 5.2 | pIC50 | = | 5.2 | Functional | ChEMBL | 539 | 23 | 3 | 4 | 7.3 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCC)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
44325422 | 113896 | 0 | None | - | 1 | Human | 5.1 | pIC50 | = | 5.1 | Functional | ChEMBL | 605 | 24 | 3 | 5 | 7.9 | CCCCCCCCCCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)c2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL316067 | 113896 | 0 | None | - | 1 | Human | 5.1 | pIC50 | = | 5.1 | Functional | ChEMBL | 605 | 24 | 3 | 5 | 7.9 | CCCCCCCCCCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)c2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
1365686 | 208187 | 36 | None | -8 | 3 | Human | 6.1 | pIC50 | = | 6.1 | Functional | ChEMBL | 404 | 5 | 1 | 6 | 3.9 | O=C(O)c1ccc2c(c1)C(=O)N(c1cccc(Oc3ccc([N+](=O)[O-])cc3)c1)C2=O | 10.1016/j.bmc.2009.09.022 | ||
CHEMBL604677 | 208187 | 36 | None | -8 | 3 | Human | 6.1 | pIC50 | = | 6.1 | Functional | ChEMBL | 404 | 5 | 1 | 6 | 3.9 | O=C(O)c1ccc2c(c1)C(=O)N(c1cccc(Oc3ccc([N+](=O)[O-])cc3)c1)C2=O | 10.1016/j.bmc.2009.09.022 | ||
11447695 | 131144 | 2 | None | 4 | 2 | Human | 6.1 | pIC50 | = | 6.1 | Functional | ChEMBL | 236 | 10 | 2 | 2 | 3.0 | C=CCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL363776 | 131144 | 2 | None | 4 | 2 | Human | 6.1 | pIC50 | = | 6.1 | Functional | ChEMBL | 236 | 10 | 2 | 2 | 3.0 | C=CCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
44414925 | 84857 | 0 | None | -72 | 2 | Human | 5.1 | pIC50 | = | 5.1 | Functional | ChEMBL | 436 | 18 | 1 | 4 | 7.1 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CC(F)P(=O)(O)O1 | 10.1021/jm060351+ | ||
CHEMBL210117 | 84857 | 0 | None | -72 | 2 | Human | 5.1 | pIC50 | = | 5.1 | Functional | ChEMBL | 436 | 18 | 1 | 4 | 7.1 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CC(F)P(=O)(O)O1 | 10.1021/jm060351+ | ||
71452131 | 89916 | 0 | None | -144 | 2 | Human | 5.1 | pIC50 | = | 5.1 | Functional | ChEMBL | 499 | 7 | 2 | 5 | 6.3 | CC(OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)cnn1C)c1ccc(F)cc1 | 10.1021/jm301022v | ||
CHEMBL2182065 | 89916 | 0 | None | -144 | 2 | Human | 5.1 | pIC50 | = | 5.1 | Functional | ChEMBL | 499 | 7 | 2 | 5 | 6.3 | CC(OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)cnn1C)c1ccc(F)cc1 | 10.1021/jm301022v | ||
11276402 | 74034 | 1 | None | - | 1 | Human | 6.1 | pIC50 | = | 6.1 | Functional | ChEMBL | 236 | 9 | 2 | 2 | 3.0 | CCCCC/C=C/CCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL188081 | 74034 | 1 | None | - | 1 | Human | 6.1 | pIC50 | = | 6.1 | Functional | ChEMBL | 236 | 9 | 2 | 2 | 3.0 | CCCCC/C=C/CCCOP(=O)(O)O | 10.1021/jm049609r | ||
66553162 | 89914 | 1 | None | -407 | 2 | Human | 5.1 | pIC50 | = | 5.1 | Functional | ChEMBL | 481 | 7 | 2 | 5 | 6.2 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)cnn1C)c1ccccc1 | 10.1021/jm301022v | ||
CHEMBL2182063 | 89914 | 1 | None | -407 | 2 | Human | 5.1 | pIC50 | = | 5.1 | Functional | ChEMBL | 481 | 7 | 2 | 5 | 6.2 | C[C@@H](OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)cnn1C)c1ccccc1 | 10.1021/jm301022v | ||
44325680 | 213976 | 0 | None | - | 1 | Human | 5.0 | pIC50 | = | 5.0 | Functional | ChEMBL | 626 | 23 | 4 | 4 | 9.1 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(Oc2cc3ccccc3[nH]2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL92584 | 213976 | 0 | None | - | 1 | Human | 5.0 | pIC50 | = | 5.0 | Functional | ChEMBL | 626 | 23 | 4 | 4 | 9.1 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(Oc2cc3ccccc3[nH]2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
44325682 | 113673 | 3 | None | -1 | 2 | Human | 6.0 | pIC50 | = | 6.0 | Functional | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
CHEMBL314555 | 113673 | 3 | None | -1 | 2 | Human | 6.0 | pIC50 | = | 6.0 | Functional | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.03.076 | ||
11197104 | 74400 | 1 | None | 4 | 3 | Human | 7.0 | pIC50 | = | 7.0 | Functional | ChEMBL | 292 | 13 | 2 | 2 | 4.6 | CCCC/C=C/CCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL190430 | 74400 | 1 | None | 4 | 3 | Human | 7.0 | pIC50 | = | 7.0 | Functional | ChEMBL | 292 | 13 | 2 | 2 | 4.6 | CCCC/C=C/CCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
11849496 | 86381 | 0 | None | -2 | 2 | Human | 5.9 | pKi | = | 5.9 | Functional | ChEMBL | 406 | 16 | 1 | 4 | 6.1 | CCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 | 10.1021/jm060351+ | ||
CHEMBL211465 | 86381 | 0 | None | -2 | 2 | Human | 5.9 | pKi | = | 5.9 | Functional | ChEMBL | 406 | 16 | 1 | 4 | 6.1 | CCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 | 10.1021/jm060351+ | ||
16725999 | 7518 | 1 | None | - | 2 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 486 | 19 | 3 | 4 | 5.7 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)Br)O | 10.1039/C4MD00255E | ||
6985 | 7518 | 1 | None | - | 2 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 486 | 19 | 3 | 4 | 5.7 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)Br)O | 10.1039/C4MD00255E | ||
CHEMBL3621357 | 7518 | 1 | None | - | 2 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 486 | 19 | 3 | 4 | 5.7 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)Br)O | 10.1039/C4MD00255E | ||
87470750 | 130595 | 0 | None | - | 0 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 512 | 20 | 3 | 4 | 6.2 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00255E | ||
CHEMBL3621353 | 130595 | 0 | None | - | 0 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 512 | 20 | 3 | 4 | 6.2 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00255E | ||
CHEMBL3623936 | 130595 | 0 | None | - | 0 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 512 | 20 | 3 | 4 | 6.2 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00255E | ||
2260227 | 190866 | 10 | None | -138 | 3 | Human | 6.5 | pKi | = | 6.5 | Functional | ChEMBL | 488 | 10 | 4 | 6 | 4.4 | O=C(O)/C=C/C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)/C=C/C(=O)O)cc3)c2)cc1 | 10.1016/j.bmc.2008.04.035 | ||
CHEMBL482498 | 190866 | 10 | None | -138 | 3 | Human | 6.5 | pKi | = | 6.5 | Functional | ChEMBL | 488 | 10 | 4 | 6 | 4.4 | O=C(O)/C=C/C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)/C=C/C(=O)O)cc3)c2)cc1 | 10.1016/j.bmc.2008.04.035 | ||
2230607 | 103175 | 4 | None | - | 1 | Human | 6.5 | pKi | = | 6.5 | Functional | ChEMBL | 310 | 5 | 3 | 3 | 2.5 | O=C(O)/C=C\C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 | 10.1016/j.bmc.2008.04.035 | ||
CHEMBL261872 | 103175 | 4 | None | - | 1 | Human | 6.5 | pKi | = | 6.5 | Functional | ChEMBL | 310 | 5 | 3 | 3 | 2.5 | O=C(O)/C=C\C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 | 10.1016/j.bmc.2008.04.035 | ||
44414925 | 84857 | 0 | None | -72 | 2 | Human | 5.5 | pKi | = | 5.5 | Functional | ChEMBL | 436 | 18 | 1 | 4 | 7.1 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CC(F)P(=O)(O)O1 | 10.1021/jm060351+ | ||
CHEMBL210117 | 84857 | 0 | None | -72 | 2 | Human | 5.5 | pKi | = | 5.5 | Functional | ChEMBL | 436 | 18 | 1 | 4 | 7.1 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CC(F)P(=O)(O)O1 | 10.1021/jm060351+ | ||
90665720 | 116043 | 0 | None | - | 0 | Human | 7.3 | pKi | = | 7.3 | Functional | ChEMBL | 702 | 27 | 3 | 6 | 9.0 | CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCC(F)(F)F)ccn2)cc1 | 10.1039/c0md00273a | ||
CHEMBL3218459 | 116043 | 0 | None | - | 0 | Human | 7.3 | pKi | = | 7.3 | Functional | ChEMBL | 702 | 27 | 3 | 6 | 9.0 | CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCC(F)(F)F)ccn2)cc1 | 10.1039/c0md00273a | ||
23725184 | 116044 | 1 | None | - | 0 | Human | 6.3 | pKi | = | 6.3 | Functional | ChEMBL | 670 | 24 | 3 | 5 | 8.8 | CCCCCCCCCCCCCCCC(=O)N[C@@H](/C=C/P(=O)(O)O)Cc1ccc(OCc2cc(OCC(F)(F)F)ccn2)cc1 | 10.1039/c0md00273a | ||
CHEMBL3218460 | 116044 | 1 | None | - | 0 | Human | 6.3 | pKi | = | 6.3 | Functional | ChEMBL | 670 | 24 | 3 | 5 | 8.8 | CCCCCCCCCCCCCCCC(=O)N[C@@H](/C=C/P(=O)(O)O)Cc1ccc(OCc2cc(OCC(F)(F)F)ccn2)cc1 | 10.1039/c0md00273a | ||
16043259 | 86584 | 0 | None | -1 | 2 | Human | 6.2 | pKi | = | 6.2 | Functional | ChEMBL | 434 | 18 | 1 | 4 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 | 10.1021/jm060351+ | ||
CHEMBL212029 | 86584 | 0 | None | -1 | 2 | Human | 6.2 | pKi | = | 6.2 | Functional | ChEMBL | 434 | 18 | 1 | 4 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 | 10.1021/jm060351+ | ||
1105689 | 190865 | 38 | None | -489 | 2 | Human | 5.2 | pKi | = | 5.2 | Functional | ChEMBL | 380 | 7 | 4 | 4 | 2.5 | O=C(O)/C=C/C(=O)Nc1ccc(-c2ccc(NC(=O)/C=C/C(=O)O)cc2)cc1 | 10.1016/j.bmc.2008.04.035 | ||
CHEMBL482497 | 190865 | 38 | None | -489 | 2 | Human | 5.2 | pKi | = | 5.2 | Functional | ChEMBL | 380 | 7 | 4 | 4 | 2.5 | O=C(O)/C=C/C(=O)Nc1ccc(-c2ccc(NC(=O)/C=C/C(=O)O)cc2)cc1 | 10.1016/j.bmc.2008.04.035 | ||
6983 | 9693 | 0 | None | -2 | 4 | Mouse | 6.3 | pEC50 | = | 6.3 | Functional | Guide to Pharmacology | 907 | 48 | 0 | 7 | 19.6 | CCCCCCCC/C=C\CCCCCCCC(=O)OP(=O)(SC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)CCCCCCC/C=C\CCCCCCCC | 16033271 | ||
73755251 | 9693 | 0 | None | -2 | 4 | Mouse | 6.3 | pEC50 | = | 6.3 | Functional | Guide to Pharmacology | 907 | 48 | 0 | 7 | 19.6 | CCCCCCCC/C=C\CCCCCCCC(=O)OP(=O)(SC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)CCCCCCC/C=C\CCCCCCCC | 16033271 | ||
2906 | 9134 | 18 | None | -31 | 12 | Mouse | 6.6 | pEC50 | = | 6.6 | Functional | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 18781939 | ||
5395 | 9134 | 18 | None | -31 | 12 | Mouse | 6.6 | pEC50 | = | 6.6 | Functional | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 18781939 | ||
5497152 | 9134 | 18 | None | -31 | 12 | Mouse | 6.6 | pEC50 | = | 6.6 | Functional | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 18781939 | ||
CHEMBL1222042 | 9134 | 18 | None | -31 | 12 | Mouse | 6.6 | pEC50 | = | 6.6 | Functional | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 18781939 | ||
16078994 | 9701 | 3 | None | - | 1 | Human | 7.2 | pEC50 | = | 7.2 | Functional | Guide to Pharmacology | 466 | 21 | 2 | 5 | 5.8 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](COP(=S)(O)O)OC | 12554733 | ||
2912 | 9701 | 3 | None | - | 1 | Human | 7.2 | pEC50 | = | 7.2 | Functional | Guide to Pharmacology | 466 | 21 | 2 | 5 | 5.8 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](COP(=S)(O)O)OC | 12554733 | ||
CHEMBL1395060 | 9701 | 3 | None | - | 1 | Human | 7.2 | pEC50 | = | 7.2 | Functional | Guide to Pharmacology | 466 | 21 | 2 | 5 | 5.8 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](COP(=S)(O)O)OC | 12554733 | ||
11313 | 7983 | 0 | None | -1 | 3 | Human | 7.2 | pEC50 | = | 7.2 | Functional | Guide to Pharmacology | 261 | 5 | 1 | 3 | 3.4 | CCN([C@H](c1cccc2c1oc(c2C)C)CO)CC | 32409422 | ||
154733034 | 7983 | 0 | None | -1 | 3 | Human | 7.2 | pEC50 | = | 7.2 | Functional | Guide to Pharmacology | 261 | 5 | 1 | 3 | 3.4 | CCN([C@H](c1cccc2c1oc(c2C)C)CO)CC | 32409422 | ||
2913 | 7135 | 0 | None | 8 | 2 | Human | 7.2 | pEC50 | = | 7.2 | Functional | Guide to Pharmacology | 452 | 22 | 2 | 4 | 6.3 | CCCCCCCC/C=C\CCCCCCCCOC[C@@H](COP(=S)(O)O)OC | 16892372 | ||
56947064 | 7135 | 0 | None | 8 | 2 | Human | 7.2 | pEC50 | = | 7.2 | Functional | Guide to Pharmacology | 452 | 22 | 2 | 4 | 6.3 | CCCCCCCC/C=C\CCCCCCCCOC[C@@H](COP(=S)(O)O)OC | 16892372 | ||
CHEMBL3621962 | 7135 | 0 | None | 8 | 2 | Human | 7.2 | pEC50 | = | 7.2 | Functional | Guide to Pharmacology | 452 | 22 | 2 | 4 | 6.3 | CCCCCCCC/C=C\CCCCCCCCOC[C@@H](COP(=S)(O)O)OC | 16892372 | ||
11314 | 7985 | 0 | None | 1 | 3 | Human | 7.7 | pEC50 | = | 7.7 | Functional | Guide to Pharmacology | 275 | 6 | 1 | 3 | 3.7 | CCN([C@H](c1cccc2c1oc(c2C)CC)CO)CC | 32409422 | ||
154733035 | 7985 | 0 | None | 1 | 3 | Human | 7.7 | pEC50 | = | 7.7 | Functional | Guide to Pharmacology | 275 | 6 | 1 | 3 | 3.7 | CCN([C@H](c1cccc2c1oc(c2C)CC)CO)CC | 32409422 | ||
10074712 | 10493 | 0 | None | 1000 | 2 | Mouse | 9.3 | pEC50 | = | 9.3 | Functional | Guide to Pharmacology | 500 | 19 | 1 | 6 | 6.7 | CCCCCCCC/C=C\CCCCCCCC(=O)O[C@@H]1COCC[C@@H]1OP(=O)(S[Na])O | 18781939 | ||
23701997 | 10493 | 0 | None | 1000 | 2 | Mouse | 9.3 | pEC50 | = | 9.3 | Functional | Guide to Pharmacology | 500 | 19 | 1 | 6 | 6.7 | CCCCCCCC/C=C\CCCCCCCC(=O)O[C@@H]1COCC[C@@H]1OP(=O)(S[Na])O | 18781939 | ||
6984 | 10493 | 0 | None | 1000 | 2 | Mouse | 9.3 | pEC50 | = | 9.3 | Functional | Guide to Pharmacology | 500 | 19 | 1 | 6 | 6.7 | CCCCCCCC/C=C\CCCCCCCC(=O)O[C@@H]1COCC[C@@H]1OP(=O)(S[Na])O | 18781939 | ||
73755252 | 10493 | 0 | None | 1000 | 2 | Mouse | 9.3 | pEC50 | = | 9.3 | Functional | Guide to Pharmacology | 500 | 19 | 1 | 6 | 6.7 | CCCCCCCC/C=C\CCCCCCCC(=O)O[C@@H]1COCC[C@@H]1OP(=O)(S[Na])O | 18781939 | ||
17757220 | 9490 | 0 | None | -165 | 3 | Mouse | 5.3 | pEC50 | > | 5.3 | Functional | Guide to Pharmacology | 405 | 19 | 3 | 3 | 5.2 | CCCCCCCC/C=C/CCCCCCCC(=O)NCCOP(=O)(O)O | 18781939 | ||
6982 | 9490 | 0 | None | -165 | 3 | Mouse | 5.3 | pEC50 | > | 5.3 | Functional | Guide to Pharmacology | 405 | 19 | 3 | 3 | 5.2 | CCCCCCCC/C=C/CCCCCCCC(=O)NCCOP(=O)(O)O | 18781939 | ||
CHEMBL1574292 | 9490 | 0 | None | -165 | 3 | Mouse | 5.3 | pEC50 | > | 5.3 | Functional | Guide to Pharmacology | 405 | 19 | 3 | 3 | 5.2 | CCCCCCCC/C=C/CCCCCCCC(=O)NCCOP(=O)(O)O | 18781939 | ||
2936 | 6873 | 0 | None | -1 | 4 | Human | 8.0 | pEC50 | None | 8 | Functional | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC(COP(=O)(O)O)CO | 10922489 | ||
56947016 | 6873 | 0 | None | -1 | 4 | Human | 8.0 | pEC50 | None | 8 | Functional | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC(COP(=O)(O)O)CO | 10922489 | ||
2915 | 7147 | 0 | None | - | 1 | Human | 9.3 | pEC50 | None | 9.3 | Functional | Guide to Pharmacology | 466 | 21 | 2 | 4 | 6.4 | CCCCCCCC/C=C/CCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)F)OC | 15857137 | ||
44400349 | 7147 | 0 | None | - | 1 | Human | 9.3 | pEC50 | None | 9.3 | Functional | Guide to Pharmacology | 466 | 21 | 2 | 4 | 6.4 | CCCCCCCC/C=C/CCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)F)OC | 15857137 | ||
CHEMBL190717 | 7147 | 0 | None | - | 1 | Human | 9.3 | pEC50 | None | 9.3 | Functional | Guide to Pharmacology | 466 | 21 | 2 | 4 | 6.4 | CCCCCCCC/C=C/CCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)F)OC | 15857137 | ||
6989 | 7767 | 0 | None | - | 1 | Mouse | 5.5 | pIC50 | = | 5.5 | Functional | Guide to Pharmacology | 297 | 2 | 1 | 4 | 3.1 | Cc1ccc(cc1)Oc1ccc2c(c1)C(=O)N(C2=O)C(=O)O | 19800804 | ||
73755253 | 7767 | 0 | None | - | 1 | Mouse | 5.5 | pIC50 | = | 5.5 | Functional | Guide to Pharmacology | 297 | 2 | 1 | 4 | 3.1 | Cc1ccc(cc1)Oc1ccc2c(c1)C(=O)N(C2=O)C(=O)O | 19800804 | ||
10282223 | 10782 | 4 | None | -5 | 3 | Human | 5.8 | pIC50 | = | 5.8 | Functional | Guide to Pharmacology | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1ccccc1)COP(=O)(O)O | 11723223 | ||
10282223 | 10782 | 4 | None | -5 | 3 | Human | 5.8 | pIC50 | = | 5.8 | Functional | Guide to Pharmacology | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1ccccc1)COP(=O)(O)O | 18781939 | ||
2909 | 10782 | 4 | None | -5 | 3 | Human | 5.8 | pIC50 | = | 5.8 | Functional | Guide to Pharmacology | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1ccccc1)COP(=O)(O)O | 11723223 | ||
2909 | 10782 | 4 | None | -5 | 3 | Human | 5.8 | pIC50 | = | 5.8 | Functional | Guide to Pharmacology | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1ccccc1)COP(=O)(O)O | 18781939 | ||
CHEMBL327240 | 10782 | 4 | None | -5 | 3 | Human | 5.8 | pIC50 | = | 5.8 | Functional | Guide to Pharmacology | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1ccccc1)COP(=O)(O)O | 11723223 | ||
CHEMBL327240 | 10782 | 4 | None | -5 | 3 | Human | 5.8 | pIC50 | = | 5.8 | Functional | Guide to Pharmacology | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1ccccc1)COP(=O)(O)O | 18781939 | ||
6579 | 8687 | 0 | None | -138 | 2 | Human | 5.9 | pIC50 | = | 5.9 | Functional | Guide to Pharmacology | 456 | 10 | 2 | 6 | 4.7 | O=C/C=C\C(=O)Nc1ccc(cc1)Oc1cccc(c1)Oc1ccc(cc1)NC(=O)/C=C\C=O | 19800804 | ||
73755226 | 8687 | 0 | None | -138 | 2 | Human | 5.9 | pIC50 | = | 5.9 | Functional | Guide to Pharmacology | 456 | 10 | 2 | 6 | 4.7 | O=C/C=C\C(=O)Nc1ccc(cc1)Oc1cccc(c1)Oc1ccc(cc1)NC(=O)/C=C\C=O | 19800804 | ||
2908 | 10786 | 0 | None | -1 | 3 | Human | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1cccnc1)COP(=O)(O)O | 15125924 | ||
44392752 | 10786 | 0 | None | -1 | 3 | Human | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1cccnc1)COP(=O)(O)O | 15125924 | ||
CHEMBL184055 | 10786 | 0 | None | -1 | 3 | Human | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1cccnc1)COP(=O)(O)O | 15125924 | ||
11132720 | 8403 | 0 | None | 4 | 4 | Human | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 19366702 | ||
2910 | 8403 | 0 | None | 4 | 4 | Human | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 19366702 | ||
DB07780 | 8403 | 0 | None | 4 | 4 | Human | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 19366702 | ||
10051843 | 8211 | 2 | None | 24 | 2 | Human | 7.0 | pIC50 | = | 7.0 | Functional | Guide to Pharmacology | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 11562440 | ||
2916 | 8211 | 2 | None | 24 | 2 | Human | 7.0 | pIC50 | = | 7.0 | Functional | Guide to Pharmacology | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 11562440 | ||
CHEMBL191055 | 8211 | 2 | None | 24 | 2 | Human | 7.0 | pIC50 | = | 7.0 | Functional | Guide to Pharmacology | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 11562440 | ||
2905 | 7177 | 49 | None | -89 | 7 | Human | 5.7 | pIC50 | None | 5.7 | Functional | Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
46240292 | 7177 | 49 | None | -89 | 7 | Human | 5.7 | pIC50 | None | 5.7 | Functional | Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
CHEMBL3621966 | 7177 | 49 | None | -89 | 7 | Human | 5.7 | pIC50 | None | 5.7 | Functional | Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
2911 | 8404 | 0 | None | -10 | 4 | Human | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | 302 | 9 | 2 | 2 | 4.5 | C/C(=C/CC/C(=C\COP(=O)(O)O)/C)/CCC=C(C)C | 19366702 | ||
6440220 | 8404 | 0 | None | -10 | 4 | Human | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | 302 | 9 | 2 | 2 | 4.5 | C/C(=C/CC/C(=C\COP(=O)(O)O)/C)/CCC=C(C)C | 19366702 | ||
2908 | 10786 | 0 | None | -1 | 3 | Human | 6.8 | pIC50 | None | 6.8 | Functional | Guide to Pharmacology | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1cccnc1)COP(=O)(O)O | 15125924 | ||
44392752 | 10786 | 0 | None | -1 | 3 | Human | 6.8 | pIC50 | None | 6.8 | Functional | Guide to Pharmacology | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1cccnc1)COP(=O)(O)O | 15125924 | ||
CHEMBL184055 | 10786 | 0 | None | -1 | 3 | Human | 6.8 | pIC50 | None | 6.8 | Functional | Guide to Pharmacology | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1cccnc1)COP(=O)(O)O | 15125924 | ||
2905 | 7177 | 49 | None | -7 | 7 | Mouse | 6.8 | pIC50 | None | 6.8 | Functional | Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
46240292 | 7177 | 49 | None | -7 | 7 | Mouse | 6.8 | pIC50 | None | 6.8 | Functional | Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
CHEMBL3621966 | 7177 | 49 | None | -7 | 7 | Mouse | 6.8 | pIC50 | None | 6.8 | Functional | Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 |
Ligands | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID | #Vendors | Reference ligand |
Fold selectivity (Affinity) |
# tested GPCRs (Affinity) |
Species | p-value (-log) |
Type | Activity Relation |
Activity Value |
Assay Type | Assay Description | Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI |
11496444 | 95834 | 0 | None | - | 0 | Human | 9.7 | pEC50 | = | 9.7 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335051 | 95834 | 0 | None | - | 0 | Human | 9.7 | pEC50 | = | 9.7 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2364959 | 95834 | 0 | None | - | 0 | Human | 9.7 | pEC50 | = | 9.7 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
11496444 | 95834 | 0 | None | - | 0 | Human | 9.7 | pEC50 | = | 9.7 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335051 | 95834 | 0 | None | - | 0 | Human | 9.7 | pEC50 | = | 9.7 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2364959 | 95834 | 0 | None | - | 0 | Human | 9.7 | pEC50 | = | 9.7 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
11648176 | 94301 | 0 | None | - | 0 | Human | 9.7 | pEC50 | = | 9.7 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335052 | 94301 | 0 | None | - | 0 | Human | 9.7 | pEC50 | = | 9.7 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
11648176 | 94301 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335052 | 94301 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
10322404 | 127859 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL357053 | 127859 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
10322404 | 127859 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL357053 | 127859 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
46223906 | 80296 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2017139 | 80296 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | ||
46223906 | 80296 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2017139 | 80296 | 0 | None | - | 0 | Human | 9.6 | pEC50 | = | 9.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | ||
71569054 | 95843 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335049 | 95843 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2365070 | 95843 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
71569054 | 95843 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335049 | 95843 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2365070 | 95843 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
71720690 | 94299 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335047 | 94299 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
71720690 | 94299 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335047 | 94299 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
71599962 | 95844 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335050 | 95844 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2365071 | 95844 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
71599962 | 95844 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335050 | 95844 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2365071 | 95844 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
44368508 | 52505 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL153043 | 52505 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
44368508 | 52505 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL153043 | 52505 | 0 | None | - | 0 | Human | 9.4 | pEC50 | = | 9.4 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
71719457 | 94300 | 0 | None | - | 0 | Human | 9.0 | pEC50 | = | 9.0 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335048 | 94300 | 0 | None | - | 0 | Human | 9.0 | pEC50 | = | 9.0 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
71719457 | 94300 | 0 | None | - | 0 | Human | 9.0 | pEC50 | = | 9.0 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL2335048 | 94300 | 0 | None | - | 0 | Human | 9.0 | pEC50 | = | 9.0 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
10432221 | 130476 | 0 | None | - | 0 | Human | 7.0 | pEC50 | = | 7.0 | Binding | ChEMBL | 419 | 19 | 3 | 3 | 5.6 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](C)COP(=O)(O)O | 10.1039/C4MD00333K | ||
CHEMBL3621958 | 130476 | 0 | None | - | 0 | Human | 7.0 | pEC50 | = | 7.0 | Binding | ChEMBL | 419 | 19 | 3 | 3 | 5.6 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](C)COP(=O)(O)O | 10.1039/C4MD00333K | ||
16045222 | 80871 | 0 | None | - | 0 | Human | 6.9 | pEC50 | = | 6.9 | Binding | ChEMBL | 440 | 18 | 2 | 6 | 4.4 | CCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL202242 | 80871 | 0 | None | - | 0 | Human | 6.9 | pEC50 | = | 6.9 | Binding | ChEMBL | 440 | 18 | 2 | 6 | 4.4 | CCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44406645 | 21647 | 0 | None | - | 0 | Rat | 6.9 | pEC50 | = | 6.9 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1207670 | 21647 | 0 | None | - | 0 | Rat | 6.9 | pEC50 | = | 6.9 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL427014 | 21647 | 0 | None | - | 0 | Rat | 6.9 | pEC50 | = | 6.9 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
44407397 | 80872 | 0 | None | - | 0 | Human | 6.8 | pEC50 | = | 6.8 | Binding | ChEMBL | 396 | 20 | 2 | 4 | 5.2 | CCCCCCCCOC[C@H](COP(=O)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL202243 | 80872 | 0 | None | - | 0 | Human | 6.8 | pEC50 | = | 6.8 | Binding | ChEMBL | 396 | 20 | 2 | 4 | 5.2 | CCCCCCCCOC[C@H](COP(=O)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
16044834 | 21469 | 0 | None | - | 0 | Rat | 6.7 | pEC50 | = | 6.7 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1206092 | 21469 | 0 | None | - | 0 | Rat | 6.7 | pEC50 | = | 6.7 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL199400 | 21469 | 0 | None | - | 0 | Rat | 6.7 | pEC50 | = | 6.7 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
16044830 | 21471 | 0 | None | - | 0 | Rat | 6.7 | pEC50 | = | 6.7 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1206094 | 21471 | 0 | None | - | 0 | Rat | 6.7 | pEC50 | = | 6.7 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL200003 | 21471 | 0 | None | - | 0 | Rat | 6.7 | pEC50 | = | 6.7 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
16044832 | 21646 | 0 | None | - | 0 | Rat | 6.6 | pEC50 | = | 6.6 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1207662 | 21646 | 0 | None | - | 0 | Rat | 6.6 | pEC50 | = | 6.6 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL425218 | 21646 | 0 | None | - | 0 | Rat | 6.6 | pEC50 | = | 6.6 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
16078994 | 9701 | 3 | None | - | 0 | Human | 6.6 | pEC50 | = | 6.6 | Binding | ChEMBL | 466 | 21 | 2 | 5 | 5.8 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](COP(=S)(O)O)OC | 10.1039/C4MD00333K | ||
2912 | 9701 | 3 | None | - | 0 | Human | 6.6 | pEC50 | = | 6.6 | Binding | ChEMBL | 466 | 21 | 2 | 5 | 5.8 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](COP(=S)(O)O)OC | 10.1039/C4MD00333K | ||
CHEMBL1395060 | 9701 | 3 | None | - | 0 | Human | 6.6 | pEC50 | = | 6.6 | Binding | ChEMBL | 466 | 21 | 2 | 5 | 5.8 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](COP(=S)(O)O)OC | 10.1039/C4MD00333K | ||
11625765 | 80160 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 412 | 20 | 2 | 4 | 5.3 | CCCCCCCCOC[C@H](COP(O)(O)=S)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL201482 | 80160 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 412 | 20 | 2 | 4 | 5.3 | CCCCCCCCOC[C@H](COP(O)(O)=S)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
58787991 | 130474 | 0 | None | - | 0 | Human | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 435 | 20 | 4 | 4 | 4.6 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](CO)COP(=O)(O)O | 10.1039/C4MD00333K | ||
CHEMBL3621956 | 130474 | 0 | None | - | 0 | Human | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 435 | 20 | 4 | 4 | 4.6 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](CO)COP(=O)(O)O | 10.1039/C4MD00333K | ||
6419701 | 132581 | 17 | None | - | 0 | Human | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL364797 | 132581 | 17 | None | - | 0 | Human | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
6419701 | 132581 | 17 | None | - | 0 | Human | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL364797 | 132581 | 17 | None | - | 0 | Human | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
16044826 | 21470 | 0 | None | - | 0 | Rat | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCCC1OCC(COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1206093 | 21470 | 0 | None | - | 0 | Rat | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCCC1OCC(COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL199472 | 21470 | 0 | None | - | 0 | Rat | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 436 | 18 | 2 | 4 | 6.0 | CCCCCCC/C=C/CCCCCCCCC1OCC(COP(O)(O)=S)O1 | 10.1016/j.bmcl.2005.08.096 | ||
10410675 | 130475 | 0 | None | - | 0 | Human | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 434 | 20 | 4 | 4 | 4.6 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](CN)COP(=O)(O)O | 10.1039/C4MD00333K | ||
CHEMBL3621957 | 130475 | 0 | None | - | 0 | Human | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 434 | 20 | 4 | 4 | 4.6 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](CN)COP(=O)(O)O | 10.1039/C4MD00333K | ||
11497157 | 21467 | 0 | None | - | 0 | Rat | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 472 | 17 | 2 | 4 | 6.1 | CCCCCCCCc1ccc(CCCCCCC2OCC(COP(O)(O)=S)O2)cc1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1206088 | 21467 | 0 | None | - | 0 | Rat | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 472 | 17 | 2 | 4 | 6.1 | CCCCCCCCc1ccc(CCCCCCC2OCC(COP(O)(O)=S)O2)cc1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL198406 | 21467 | 0 | None | - | 0 | Rat | 6.2 | pEC50 | = | 6.2 | Binding | ChEMBL | 472 | 17 | 2 | 4 | 6.1 | CCCCCCCCc1ccc(CCCCCCC2OCC(COP(O)(O)=S)O2)cc1 | 10.1016/j.bmcl.2005.08.096 | ||
44406650 | 21593 | 0 | None | - | 0 | Rat | 5.1 | pEC50 | = | 5.1 | Binding | ChEMBL | 416 | 16 | 2 | 4 | 5.4 | C/C=C/C/C=C/C/C=C/CCCCCCCCC1OCC(COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1207268 | 21593 | 0 | None | - | 0 | Rat | 5.1 | pEC50 | = | 5.1 | Binding | ChEMBL | 416 | 16 | 2 | 4 | 5.4 | C/C=C/C/C=C/C/C=C/CCCCCCCCC1OCC(COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL383362 | 21593 | 0 | None | - | 0 | Rat | 5.1 | pEC50 | = | 5.1 | Binding | ChEMBL | 416 | 16 | 2 | 4 | 5.4 | C/C=C/C/C=C/C/C=C/CCCCCCCCC1OCC(COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
5311263 | 10929 | 22 | None | - | 1 | Human | 7.1 | pEC50 | = | 7.1 | Binding | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL117021 | 10929 | 22 | None | - | 1 | Human | 7.1 | pEC50 | = | 7.1 | Binding | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
5311263 | 10929 | 22 | None | - | 1 | Human | 7.1 | pEC50 | = | 7.1 | Binding | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
CHEMBL117021 | 10929 | 22 | None | - | 1 | Human | 7.1 | pEC50 | = | 7.1 | Binding | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
11568387 | 81013 | 0 | None | 72 | 2 | Human | 8.0 | pIC50 | = | 8.0 | Binding | ChEMBL | 440 | 18 | 2 | 6 | 4.4 | CCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL202361 | 81013 | 0 | None | 72 | 2 | Human | 8.0 | pIC50 | = | 8.0 | Binding | ChEMBL | 440 | 18 | 2 | 6 | 4.4 | CCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
16044836 | 21654 | 0 | None | - | 1 | Rat | 6.9 | pIC50 | = | 6.9 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1207755 | 21654 | 0 | None | - | 1 | Rat | 6.9 | pIC50 | = | 6.9 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL436763 | 21654 | 0 | None | - | 1 | Rat | 6.9 | pIC50 | = | 6.9 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
44407394 | 82178 | 0 | None | 9 | 2 | Human | 6.8 | pIC50 | = | 6.8 | Binding | ChEMBL | 396 | 20 | 2 | 4 | 5.2 | CCCCCCCCOC[C@@H](COP(=O)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL203986 | 82178 | 0 | None | 9 | 2 | Human | 6.8 | pIC50 | = | 6.8 | Binding | ChEMBL | 396 | 20 | 2 | 4 | 5.2 | CCCCCCCCOC[C@@H](COP(=O)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
23629653 | 190868 | 1 | None | - | 0 | Human | 6.8 | pIC50 | = | 6.8 | Binding | ChEMBL | 396 | 16 | 2 | 6 | 3.5 | CCCCCCC(=O)OC[C@H](COP(=O)(O)O)OC(=O)CCCCCC | 10.1016/j.bmc.2008.04.035 | ||
CHEMBL482505 | 190868 | 1 | None | - | 0 | Human | 6.8 | pIC50 | = | 6.8 | Binding | ChEMBL | 396 | 16 | 2 | 6 | 3.5 | CCCCCCC(=O)OC[C@H](COP(=O)(O)O)OC(=O)CCCCCC | 10.1016/j.bmc.2008.04.035 | ||
10393842 | 175978 | 0 | None | -9 | 2 | Human | 6.8 | pIC50 | = | 6.8 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1039/C4MD00333K | ||
CHEMBL440696 | 175978 | 0 | None | -9 | 2 | Human | 6.8 | pIC50 | = | 6.8 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1039/C4MD00333K | ||
44407389 | 9683 | 0 | None | 2 | 2 | Human | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 412 | 20 | 2 | 4 | 5.3 | CCCCCCCCOC[C@@H](COP(=S)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
6995 | 9683 | 0 | None | 2 | 2 | Human | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 412 | 20 | 2 | 4 | 5.3 | CCCCCCCCOC[C@@H](COP(=S)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL427017 | 9683 | 0 | None | 2 | 2 | Human | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 412 | 20 | 2 | 4 | 5.3 | CCCCCCCCOC[C@@H](COP(=S)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44586491 | 190869 | 0 | None | - | 0 | Human | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 412 | 16 | 2 | 6 | 3.6 | CCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC(=O)CCCCCC | 10.1016/j.bmc.2008.04.035 | ||
CHEMBL482506 | 190869 | 0 | None | - | 0 | Human | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 412 | 16 | 2 | 6 | 3.6 | CCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC(=O)CCCCCC | 10.1016/j.bmc.2008.04.035 | ||
11101949 | 148038 | 0 | None | 1 | 2 | Human | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 424 | 18 | 2 | 6 | 4.3 | CCCCCCCC(=O)OC[C@@H](COP(=O)(O)O)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL383095 | 148038 | 0 | None | 1 | 2 | Human | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 424 | 18 | 2 | 6 | 4.3 | CCCCCCCC(=O)OC[C@@H](COP(=O)(O)O)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44406681 | 21587 | 0 | None | - | 1 | Rat | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1207238 | 21587 | 0 | None | - | 1 | Rat | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL370846 | 21587 | 0 | None | - | 1 | Rat | 6.7 | pIC50 | = | 6.7 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
44407386 | 175929 | 0 | None | 1 | 2 | Human | 6.6 | pIC50 | = | 6.6 | Binding | ChEMBL | 438 | 18 | 4 | 4 | 3.5 | CCCCCCCCNC(=O)[C@H](COP(O)(O)=S)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL440396 | 175929 | 0 | None | 1 | 2 | Human | 6.6 | pIC50 | = | 6.6 | Binding | ChEMBL | 438 | 18 | 4 | 4 | 3.5 | CCCCCCCCNC(=O)[C@H](COP(O)(O)=S)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44407485 | 146089 | 0 | None | 24 | 2 | Human | 6.5 | pIC50 | = | 6.5 | Binding | ChEMBL | 438 | 18 | 4 | 4 | 3.5 | CCCCCCCCNC(=O)[C@@H](COP(O)(O)=S)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL379248 | 146089 | 0 | None | 24 | 2 | Human | 6.5 | pIC50 | = | 6.5 | Binding | ChEMBL | 438 | 18 | 4 | 4 | 3.5 | CCCCCCCCNC(=O)[C@@H](COP(O)(O)=S)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44394293 | 82186 | 0 | None | - | 1 | Human | 6.4 | pIC50 | = | 6.4 | Binding | ChEMBL | 422 | 18 | 4 | 4 | 3.4 | CCCCCCCCNC(=O)[C@H](COP(=O)(O)O)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL204037 | 82186 | 0 | None | - | 1 | Human | 6.4 | pIC50 | = | 6.4 | Binding | ChEMBL | 422 | 18 | 4 | 4 | 3.4 | CCCCCCCCNC(=O)[C@H](COP(=O)(O)O)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44406676 | 21592 | 0 | None | - | 1 | Rat | 6.3 | pIC50 | = | 6.3 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1207267 | 21592 | 0 | None | - | 1 | Rat | 6.3 | pIC50 | = | 6.3 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL382116 | 21592 | 0 | None | - | 1 | Rat | 6.3 | pIC50 | = | 6.3 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
44406670 | 21468 | 0 | None | 11 | 2 | Rat | 6.3 | pIC50 | = | 6.3 | Binding | ChEMBL | 456 | 17 | 2 | 4 | 5.9 | CCCCCCCCc1ccc(CCCCCCC2OCC(COP(=O)(O)O)O2)cc1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1206091 | 21468 | 0 | None | 11 | 2 | Rat | 6.3 | pIC50 | = | 6.3 | Binding | ChEMBL | 456 | 17 | 2 | 4 | 5.9 | CCCCCCCCc1ccc(CCCCCCC2OCC(COP(=O)(O)O)O2)cc1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL199380 | 21468 | 0 | None | 11 | 2 | Rat | 6.3 | pIC50 | = | 6.3 | Binding | ChEMBL | 456 | 17 | 2 | 4 | 5.9 | CCCCCCCCc1ccc(CCCCCCC2OCC(COP(=O)(O)O)O2)cc1 | 10.1016/j.bmcl.2005.08.096 | ||
9960370 | 118326 | 2 | None | - | 0 | Human | 5.2 | pIC50 | = | 5.2 | Binding | ChEMBL | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccccc2)cc1 | 10.1039/C4MD00333K | ||
CHEMBL328016 | 118326 | 2 | None | - | 0 | Human | 5.2 | pIC50 | = | 5.2 | Binding | ChEMBL | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccccc2)cc1 | 10.1039/C4MD00333K | ||
128167 | 80766 | 12 | None | 10 | 2 | Human | 7.1 | pIC50 | = | 7.1 | Binding | ChEMBL | 424 | 18 | 2 | 6 | 4.3 | CCCCCCCC(=O)OC[C@H](COP(=O)(O)O)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL202185 | 80766 | 12 | None | 10 | 2 | Human | 7.1 | pIC50 | = | 7.1 | Binding | ChEMBL | 424 | 18 | 2 | 6 | 4.3 | CCCCCCCC(=O)OC[C@H](COP(=O)(O)O)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44407385 | 80874 | 0 | None | - | 1 | Human | 6.0 | pIC50 | = | 6.0 | Binding | ChEMBL | 422 | 18 | 4 | 4 | 3.4 | CCCCCCCCNC(=O)[C@@H](COP(=O)(O)O)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL202251 | 80874 | 0 | None | - | 1 | Human | 6.0 | pIC50 | = | 6.0 | Binding | ChEMBL | 422 | 18 | 4 | 4 | 3.4 | CCCCCCCCNC(=O)[C@@H](COP(=O)(O)O)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44392791 | 103697 | 0 | None | - | 1 | Human | 7.0 | pKi | = | 7.0 | Binding | ChEMBL | 632 | 25 | 3 | 6 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OC)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL265967 | 103697 | 0 | None | - | 1 | Human | 7.0 | pKi | = | 7.0 | Binding | ChEMBL | 632 | 25 | 3 | 6 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OC)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44392834 | 129169 | 0 | None | - | 1 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 574 | 23 | 3 | 4 | 7.7 | CCCCCCCCCCCCCCCC(=O)N[C@H](CCP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL360064 | 129169 | 0 | None | - | 1 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 574 | 23 | 3 | 4 | 7.7 | CCCCCCCCCCCCCCCC(=O)N[C@H](CCP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
753410 | 208735 | 10 | None | -3 | 2 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 311 | 4 | 1 | 4 | 2.5 | Cc1ccc(Oc2ccc3c(c2)C(=O)N(CC(=O)O)C3=O)cc1 | 10.1016/j.bmc.2009.09.022 | ||
CHEMBL607806 | 208735 | 10 | None | -3 | 2 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 311 | 4 | 1 | 4 | 2.5 | Cc1ccc(Oc2ccc3c(c2)C(=O)N(CC(=O)O)C3=O)cc1 | 10.1016/j.bmc.2009.09.022 | ||
44392780 | 212649 | 0 | None | - | 1 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 632 | 25 | 3 | 6 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL83782 | 212649 | 0 | None | - | 1 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 632 | 25 | 3 | 6 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
78401 | 74622 | 60 | None | 3 | 2 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 278 | 13 | 2 | 1 | 4.9 | CCCCCCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL190999 | 74622 | 60 | None | 3 | 2 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 278 | 13 | 2 | 1 | 4.9 | CCCCCCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
44392725 | 129828 | 0 | None | - | 1 | Human | 5.9 | pKi | = | 5.9 | Binding | ChEMBL | 682 | 25 | 3 | 6 | 9.0 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OC)c3ccccc3n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL360928 | 129828 | 0 | None | - | 1 | Human | 5.9 | pKi | = | 5.9 | Binding | ChEMBL | 682 | 25 | 3 | 6 | 9.0 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OC)c3ccccc3n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44407386 | 175929 | 0 | None | 1 | 2 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 438 | 18 | 4 | 4 | 3.5 | CCCCCCCCNC(=O)[C@H](COP(O)(O)=S)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL440396 | 175929 | 0 | None | 1 | 2 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 438 | 18 | 4 | 4 | 3.5 | CCCCCCCCNC(=O)[C@H](COP(O)(O)=S)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44407485 | 146089 | 0 | None | 24 | 2 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 438 | 18 | 4 | 4 | 3.5 | CCCCCCCCNC(=O)[C@@H](COP(O)(O)=S)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL379248 | 146089 | 0 | None | 24 | 2 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 438 | 18 | 4 | 4 | 3.5 | CCCCCCCCNC(=O)[C@@H](COP(O)(O)=S)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
11101949 | 148038 | 0 | None | 1 | 2 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 424 | 18 | 2 | 6 | 4.3 | CCCCCCCC(=O)OC[C@@H](COP(=O)(O)O)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL383095 | 148038 | 0 | None | 1 | 2 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 424 | 18 | 2 | 6 | 4.3 | CCCCCCCC(=O)OC[C@@H](COP(=O)(O)O)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
4030 | 8140 | 19 | None | - | 1 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 238 | 10 | 2 | 2 | 3.2 | CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
62532 | 8140 | 19 | None | - | 1 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 238 | 10 | 2 | 2 | 3.2 | CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL361255 | 8140 | 19 | None | - | 1 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 238 | 10 | 2 | 2 | 3.2 | CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
75816 | 73947 | 53 | None | 11 | 2 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 266 | 12 | 2 | 2 | 4.0 | CCCCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL187711 | 73947 | 53 | None | 11 | 2 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 266 | 12 | 2 | 2 | 4.0 | CCCCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
11288209 | 131168 | 2 | None | - | 1 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 252 | 10 | 2 | 2 | 3.1 | C=CCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL363935 | 131168 | 2 | None | - | 1 | Human | 6.9 | pKi | = | 6.9 | Binding | ChEMBL | 252 | 10 | 2 | 2 | 3.1 | C=CCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
10468943 | 8239 | 5 | None | -1 | 2 | Human | 7.9 | pKi | = | 7.9 | Binding | ChEMBL | 282 | 12 | 2 | 2 | 4.1 | CCCCCCCCCCCCOP(=S)(O)O | 10.1021/jm049609r | ||
6990 | 8239 | 5 | None | -1 | 2 | Human | 7.9 | pKi | = | 7.9 | Binding | ChEMBL | 282 | 12 | 2 | 2 | 4.1 | CCCCCCCCCCCCOP(=S)(O)O | 10.1021/jm049609r | ||
CHEMBL191365 | 8239 | 5 | None | -1 | 2 | Human | 7.9 | pKi | = | 7.9 | Binding | ChEMBL | 282 | 12 | 2 | 2 | 4.1 | CCCCCCCCCCCCOP(=S)(O)O | 10.1021/jm049609r | ||
11220562 | 73883 | 0 | None | - | 1 | Human | 7.9 | pKi | = | 7.9 | Binding | ChEMBL | 308 | 13 | 2 | 2 | 4.7 | CCCC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL187402 | 73883 | 0 | None | - | 1 | Human | 7.9 | pKi | = | 7.9 | Binding | ChEMBL | 308 | 13 | 2 | 2 | 4.7 | CCCC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
11208266 | 74406 | 1 | None | - | 1 | Human | 7.9 | pKi | = | 7.9 | Binding | ChEMBL | 280 | 11 | 2 | 2 | 3.9 | CC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL190484 | 74406 | 1 | None | - | 1 | Human | 7.9 | pKi | = | 7.9 | Binding | ChEMBL | 280 | 11 | 2 | 2 | 3.9 | CC/C=C/CCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
10367662 | 8967 | 91 | None | 1 | 3 | Human | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 10.1021/jm049609r | ||
2907 | 8967 | 91 | None | 1 | 3 | Human | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 10.1021/jm049609r | ||
CHEMBL361501 | 8967 | 91 | None | 1 | 3 | Human | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 10.1021/jm049609r | ||
44392835 | 72031 | 0 | None | - | 1 | Human | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 658 | 25 | 3 | 5 | 8.9 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](CCP(=O)(O)O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL182773 | 72031 | 0 | None | - | 1 | Human | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 658 | 25 | 3 | 5 | 8.9 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](CCP(=O)(O)O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44392794 | 107297 | 0 | None | -25 | 2 | Human | 5.8 | pKi | = | 5.8 | Binding | ChEMBL | 660 | 27 | 3 | 6 | 8.6 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCCC)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL291229 | 107297 | 0 | None | -25 | 2 | Human | 5.8 | pKi | = | 5.8 | Binding | ChEMBL | 660 | 27 | 3 | 6 | 8.6 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCCC)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
2908 | 10786 | 0 | None | -95 | 2 | Human | 5.8 | pKi | = | 5.8 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1cccnc1)COP(=O)(O)O | 10.1016/j.bmcl.2004.05.023 | ||
44392752 | 10786 | 0 | None | -95 | 2 | Human | 5.8 | pKi | = | 5.8 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1cccnc1)COP(=O)(O)O | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL184055 | 10786 | 0 | None | -95 | 2 | Human | 5.8 | pKi | = | 5.8 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1cccnc1)COP(=O)(O)O | 10.1016/j.bmcl.2004.05.023 | ||
44406670 | 21468 | 0 | None | 11 | 2 | Rat | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 456 | 17 | 2 | 4 | 5.9 | CCCCCCCCc1ccc(CCCCCCC2OCC(COP(=O)(O)O)O2)cc1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1206091 | 21468 | 0 | None | 11 | 2 | Rat | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 456 | 17 | 2 | 4 | 5.9 | CCCCCCCCc1ccc(CCCCCCC2OCC(COP(=O)(O)O)O2)cc1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL199380 | 21468 | 0 | None | 11 | 2 | Rat | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 456 | 17 | 2 | 4 | 5.9 | CCCCCCCCc1ccc(CCCCCCC2OCC(COP(=O)(O)O)O2)cc1 | 10.1016/j.bmcl.2005.08.096 | ||
10393842 | 175978 | 0 | None | -9 | 2 | Human | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL440696 | 175978 | 0 | None | -9 | 2 | Human | 6.8 | pKi | = | 6.8 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44394293 | 82186 | 0 | None | - | 1 | Human | 6.7 | pKi | = | 6.7 | Binding | ChEMBL | 422 | 18 | 4 | 4 | 3.4 | CCCCCCCCNC(=O)[C@H](COP(=O)(O)O)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL204037 | 82186 | 0 | None | - | 1 | Human | 6.7 | pKi | = | 6.7 | Binding | ChEMBL | 422 | 18 | 4 | 4 | 3.4 | CCCCCCCCNC(=O)[C@H](COP(=O)(O)O)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
10051843 | 8211 | 2 | None | 15 | 2 | Human | 6.7 | pKi | = | 6.7 | Binding | ChEMBL | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 10.1021/jm049609r | ||
2916 | 8211 | 2 | None | 15 | 2 | Human | 6.7 | pKi | = | 6.7 | Binding | ChEMBL | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 10.1021/jm049609r | ||
CHEMBL191055 | 8211 | 2 | None | 15 | 2 | Human | 6.7 | pKi | = | 6.7 | Binding | ChEMBL | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 10.1021/jm049609r | ||
44392769 | 129439 | 0 | None | - | 1 | Human | 5.7 | pKi | = | 5.7 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccncc2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL360399 | 129439 | 0 | None | - | 1 | Human | 5.7 | pKi | = | 5.7 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccncc2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
82327 | 73933 | 14 | None | 5 | 2 | Human | 6.7 | pKi | = | 6.7 | Binding | ChEMBL | 294 | 14 | 2 | 2 | 4.8 | CCCCCCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL187633 | 73933 | 14 | None | 5 | 2 | Human | 6.7 | pKi | = | 6.7 | Binding | ChEMBL | 294 | 14 | 2 | 2 | 4.8 | CCCCCCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
1365686 | 208187 | 36 | None | -4 | 3 | Human | 6.6 | pKi | = | 6.6 | Binding | ChEMBL | 404 | 5 | 1 | 6 | 3.9 | O=C(O)c1ccc2c(c1)C(=O)N(c1cccc(Oc3ccc([N+](=O)[O-])cc3)c1)C2=O | 10.1016/j.bmc.2009.09.022 | ||
CHEMBL604677 | 208187 | 36 | None | -4 | 3 | Human | 6.6 | pKi | = | 6.6 | Binding | ChEMBL | 404 | 5 | 1 | 6 | 3.9 | O=C(O)c1ccc2c(c1)C(=O)N(c1cccc(Oc3ccc([N+](=O)[O-])cc3)c1)C2=O | 10.1016/j.bmc.2009.09.022 | ||
44392848 | 71356 | 0 | None | - | 1 | Human | 6.6 | pKi | = | 6.6 | Binding | ChEMBL | 615 | 24 | 4 | 4 | 8.2 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)CC(O)P(=O)(O)O | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL181612 | 71356 | 0 | None | - | 1 | Human | 6.6 | pKi | = | 6.6 | Binding | ChEMBL | 615 | 24 | 4 | 4 | 8.2 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)CC(O)P(=O)(O)O | 10.1016/j.bmcl.2004.05.023 | ||
11755685 | 74284 | 0 | None | - | 1 | Human | 5.6 | pKi | = | 5.6 | Binding | ChEMBL | 499 | 20 | 4 | 4 | 5.8 | CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(OP(=O)(O)O)cc1)C(=O)O | 10.1021/jm049609r | ||
CHEMBL189515 | 74284 | 0 | None | - | 1 | Human | 5.6 | pKi | = | 5.6 | Binding | ChEMBL | 499 | 20 | 4 | 4 | 5.8 | CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(OP(=O)(O)O)cc1)C(=O)O | 10.1021/jm049609r | ||
44406676 | 21592 | 0 | None | - | 1 | Rat | 6.6 | pKi | = | 6.6 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1207267 | 21592 | 0 | None | - | 1 | Rat | 6.6 | pKi | = | 6.6 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL382116 | 21592 | 0 | None | - | 1 | Rat | 6.6 | pKi | = | 6.6 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
44392726 | 71767 | 0 | None | - | 1 | Human | 5.6 | pKi | = | 5.6 | Binding | ChEMBL | 682 | 25 | 3 | 6 | 9.0 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OC)c3ccccc3n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL182302 | 71767 | 0 | None | - | 1 | Human | 5.6 | pKi | = | 5.6 | Binding | ChEMBL | 682 | 25 | 3 | 6 | 9.0 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OC)c3ccccc3n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
11219269 | 74391 | 1 | None | - | 1 | Human | 7.6 | pKi | = | 7.6 | Binding | ChEMBL | 264 | 11 | 2 | 2 | 3.8 | CC/C=C/CCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL190349 | 74391 | 1 | None | - | 1 | Human | 7.6 | pKi | = | 7.6 | Binding | ChEMBL | 264 | 11 | 2 | 2 | 3.8 | CC/C=C/CCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
78816 | 130820 | 56 | None | - | 1 | Human | 6.5 | pKi | = | 6.5 | Binding | ChEMBL | 250 | 11 | 2 | 1 | 4.1 | CCCCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL363067 | 130820 | 56 | None | - | 1 | Human | 6.5 | pKi | = | 6.5 | Binding | ChEMBL | 250 | 11 | 2 | 1 | 4.1 | CCCCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
11276402 | 74034 | 1 | None | - | 1 | Human | 6.4 | pKi | = | 6.4 | Binding | ChEMBL | 236 | 9 | 2 | 2 | 3.0 | CCCCC/C=C/CCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL188081 | 74034 | 1 | None | - | 1 | Human | 6.4 | pKi | = | 6.4 | Binding | ChEMBL | 236 | 9 | 2 | 2 | 3.0 | CCCCC/C=C/CCCOP(=O)(O)O | 10.1021/jm049609r | ||
128167 | 80766 | 12 | None | 10 | 2 | Human | 7.4 | pKi | = | 7.4 | Binding | ChEMBL | 424 | 18 | 2 | 6 | 4.3 | CCCCCCCC(=O)OC[C@H](COP(=O)(O)O)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL202185 | 80766 | 12 | None | 10 | 2 | Human | 7.4 | pKi | = | 7.4 | Binding | ChEMBL | 424 | 18 | 2 | 6 | 4.3 | CCCCCCCC(=O)OC[C@H](COP(=O)(O)O)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44392792 | 72346 | 0 | None | -1 | 2 | Human | 7.4 | pKi | = | 7.4 | Binding | ChEMBL | 646 | 26 | 3 | 6 | 8.2 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCC)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL183143 | 72346 | 0 | None | -1 | 2 | Human | 7.4 | pKi | = | 7.4 | Binding | ChEMBL | 646 | 26 | 3 | 6 | 8.2 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCC)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44392796 | 130441 | 0 | None | -1 | 2 | Human | 7.4 | pKi | = | 7.4 | Binding | ChEMBL | 660 | 25 | 3 | 6 | 8.5 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL362053 | 130441 | 0 | None | -1 | 2 | Human | 7.4 | pKi | = | 7.4 | Binding | ChEMBL | 660 | 25 | 3 | 6 | 8.5 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
11312382 | 74131 | 1 | None | 11 | 2 | Human | 7.4 | pKi | = | 7.4 | Binding | ChEMBL | 292 | 13 | 2 | 2 | 4.6 | CC/C=C/CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL188591 | 74131 | 1 | None | 11 | 2 | Human | 7.4 | pKi | = | 7.4 | Binding | ChEMBL | 292 | 13 | 2 | 2 | 4.6 | CC/C=C/CCCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
44392836 | 134323 | 0 | None | - | 1 | Human | 5.4 | pKi | = | 5.4 | Binding | ChEMBL | 658 | 25 | 3 | 5 | 8.9 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](CCP(=O)(O)O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL366292 | 134323 | 0 | None | - | 1 | Human | 5.4 | pKi | = | 5.4 | Binding | ChEMBL | 658 | 25 | 3 | 5 | 8.9 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](CCP(=O)(O)O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44392795 | 71944 | 0 | None | -12 | 2 | Human | 6.4 | pKi | = | 6.4 | Binding | ChEMBL | 676 | 28 | 3 | 7 | 7.9 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCCOC)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL182446 | 71944 | 0 | None | -12 | 2 | Human | 6.4 | pKi | = | 6.4 | Binding | ChEMBL | 676 | 28 | 3 | 7 | 7.9 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCCOC)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44392779 | 73426 | 0 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 632 | 25 | 3 | 6 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL185287 | 73426 | 0 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 632 | 25 | 3 | 6 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cccc(OC)n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44392793 | 72359 | 0 | None | -2 | 2 | Human | 7.3 | pKi | = | 7.3 | Binding | ChEMBL | 700 | 26 | 3 | 6 | 8.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCC(F)(F)F)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL183221 | 72359 | 0 | None | -2 | 2 | Human | 7.3 | pKi | = | 7.3 | Binding | ChEMBL | 700 | 26 | 3 | 6 | 8.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2cc(OCC(F)(F)F)ccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44407385 | 80874 | 0 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 422 | 18 | 4 | 4 | 3.4 | CCCCCCCCNC(=O)[C@@H](COP(=O)(O)O)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL202251 | 80874 | 0 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 422 | 18 | 4 | 4 | 3.4 | CCCCCCCCNC(=O)[C@@H](COP(=O)(O)O)NC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
11242245 | 73972 | 5 | None | - | 1 | Human | 7.3 | pKi | = | 7.3 | Binding | ChEMBL | 254 | 10 | 2 | 2 | 3.4 | CCCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL187795 | 73972 | 5 | None | - | 1 | Human | 7.3 | pKi | = | 7.3 | Binding | ChEMBL | 254 | 10 | 2 | 2 | 3.4 | CCCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
11568387 | 81013 | 0 | None | 72 | 2 | Human | 8.3 | pKi | = | 8.3 | Binding | ChEMBL | 440 | 18 | 2 | 6 | 4.4 | CCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL202361 | 81013 | 0 | None | 72 | 2 | Human | 8.3 | pKi | = | 8.3 | Binding | ChEMBL | 440 | 18 | 2 | 6 | 4.4 | CCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC(=O)CCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
44407394 | 82178 | 0 | None | 9 | 2 | Human | 7.3 | pKi | = | 7.3 | Binding | ChEMBL | 396 | 20 | 2 | 4 | 5.2 | CCCCCCCCOC[C@@H](COP(=O)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL203986 | 82178 | 0 | None | 9 | 2 | Human | 7.3 | pKi | = | 7.3 | Binding | ChEMBL | 396 | 20 | 2 | 4 | 5.2 | CCCCCCCCOC[C@@H](COP(=O)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
11447695 | 131144 | 2 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 236 | 10 | 2 | 2 | 3.0 | C=CCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL363776 | 131144 | 2 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 236 | 10 | 2 | 2 | 3.0 | C=CCCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
44392798 | 129318 | 0 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 652 | 24 | 3 | 5 | 9.0 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccc3ccccc3n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL360131 | 129318 | 0 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 652 | 24 | 3 | 5 | 9.0 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](COP(=O)(O)O)Cc1ccc(OCc2ccc3ccccc3n2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44392797 | 71540 | 0 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 660 | 25 | 3 | 6 | 8.5 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL181917 | 71540 | 0 | None | - | 1 | Human | 6.3 | pKi | = | 6.3 | Binding | ChEMBL | 660 | 25 | 3 | 6 | 8.5 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
11393306 | 74189 | 1 | None | 1 | 2 | Human | 6.2 | pKi | = | 6.2 | Binding | ChEMBL | 328 | 14 | 2 | 1 | 5.8 | CCCCCCCCCCCCCCC(F)(F)P(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL188859 | 74189 | 1 | None | 1 | 2 | Human | 6.2 | pKi | = | 6.2 | Binding | ChEMBL | 328 | 14 | 2 | 1 | 5.8 | CCCCCCCCCCCCCCC(F)(F)P(=O)(O)O | 10.1021/jm049609r | ||
11197104 | 74400 | 1 | None | 19 | 2 | Human | 7.2 | pKi | = | 7.2 | Binding | ChEMBL | 292 | 13 | 2 | 2 | 4.6 | CCCC/C=C/CCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL190430 | 74400 | 1 | None | 19 | 2 | Human | 7.2 | pKi | = | 7.2 | Binding | ChEMBL | 292 | 13 | 2 | 2 | 4.6 | CCCC/C=C/CCCCCCCCOP(=O)(O)O | 10.1021/jm049609r | ||
44397968 | 74808 | 0 | None | - | 1 | Human | 6.2 | pKi | = | 6.2 | Binding | ChEMBL | 603 | 25 | 3 | 4 | 8.7 | CCCCCCCCCCCCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccccc2)cc1 | 10.1021/jm049609r | ||
CHEMBL191411 | 74808 | 0 | None | - | 1 | Human | 6.2 | pKi | = | 6.2 | Binding | ChEMBL | 603 | 25 | 3 | 4 | 8.7 | CCCCCCCCCCCCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccccc2)cc1 | 10.1021/jm049609r | ||
44392762 | 129726 | 0 | None | - | 1 | Human | 5.2 | pKi | = | 5.2 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2cccnc2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL360727 | 129726 | 0 | None | - | 1 | Human | 5.2 | pKi | = | 5.2 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2cccnc2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
44407389 | 9683 | 0 | None | 2 | 2 | Human | 7.2 | pKi | = | 7.2 | Binding | ChEMBL | 412 | 20 | 2 | 4 | 5.3 | CCCCCCCCOC[C@@H](COP(=S)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
6995 | 9683 | 0 | None | 2 | 2 | Human | 7.2 | pKi | = | 7.2 | Binding | ChEMBL | 412 | 20 | 2 | 4 | 5.3 | CCCCCCCCOC[C@@H](COP(=S)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
CHEMBL427017 | 9683 | 0 | None | 2 | 2 | Human | 7.2 | pKi | = | 7.2 | Binding | ChEMBL | 412 | 20 | 2 | 4 | 5.3 | CCCCCCCCOC[C@@H](COP(=S)(O)O)OCCCCCCCC | 10.1016/j.bmcl.2005.10.031 | ||
81309 | 74035 | 68 | None | - | 1 | Human | 6.2 | pKi | = | 6.2 | Binding | ChEMBL | 222 | 9 | 2 | 1 | 3.3 | CCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
88299705 | 74035 | 68 | None | - | 1 | Human | 6.2 | pKi | = | 6.2 | Binding | ChEMBL | 222 | 9 | 2 | 1 | 3.3 | CCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
CHEMBL188083 | 74035 | 68 | None | - | 1 | Human | 6.2 | pKi | = | 6.2 | Binding | ChEMBL | 222 | 9 | 2 | 1 | 3.3 | CCCCCCCCCCP(=O)(O)O | 10.1021/jm049609r | ||
44392778 | 129438 | 0 | None | - | 1 | Human | 5.2 | pKi | = | 5.2 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccncc2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL360397 | 129438 | 0 | None | - | 1 | Human | 5.2 | pKi | = | 5.2 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccncc2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
11312936 | 74260 | 0 | None | - | 1 | Human | 7.1 | pKi | = | 7.1 | Binding | ChEMBL | 310 | 14 | 2 | 2 | 4.9 | CCCCCCCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
CHEMBL189296 | 74260 | 0 | None | - | 1 | Human | 7.1 | pKi | = | 7.1 | Binding | ChEMBL | 310 | 14 | 2 | 2 | 4.9 | CCCCCCCCCCCCCCOP(O)(O)=S | 10.1021/jm049609r | ||
44406681 | 21587 | 0 | None | - | 1 | Rat | 7.1 | pKi | = | 7.1 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1207238 | 21587 | 0 | None | - | 1 | Rat | 7.1 | pKi | = | 7.1 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL370846 | 21587 | 0 | None | - | 1 | Rat | 7.1 | pKi | = | 7.1 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@H]1OC[C@@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
16044836 | 21654 | 0 | None | - | 1 | Rat | 7.1 | pKi | = | 7.1 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL1207755 | 21654 | 0 | None | - | 1 | Rat | 7.1 | pKi | = | 7.1 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
CHEMBL436763 | 21654 | 0 | None | - | 1 | Rat | 7.1 | pKi | = | 7.1 | Binding | ChEMBL | 420 | 18 | 2 | 4 | 5.9 | CCCCCCC/C=C/CCCCCCCC[C@@H]1OC[C@H](COP(=O)(O)O)O1 | 10.1016/j.bmcl.2005.08.096 | ||
44325682 | 113673 | 3 | None | -6 | 2 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
CHEMBL314555 | 113673 | 3 | None | -6 | 2 | Human | 6.0 | pKi | = | 6.0 | Binding | ChEMBL | 602 | 24 | 3 | 5 | 7.8 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](COP(=O)(O)O)Cc1ccc(OCc2ccccn2)cc1 | 10.1016/j.bmcl.2004.05.023 | ||
2906 | 9134 | 18 | None | -31 | 4 | Human | 6.7 | pKd | None | 6.7 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10488122 | ||
5395 | 9134 | 18 | None | -31 | 4 | Human | 6.7 | pKd | None | 6.7 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10488122 | ||
5497152 | 9134 | 18 | None | -31 | 4 | Human | 6.7 | pKd | None | 6.7 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10488122 | ||
CHEMBL1222042 | 9134 | 18 | None | -31 | 4 | Human | 6.7 | pKd | None | 6.7 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10488122 | ||
11132720 | 8403 | 0 | None | - | 1 | Human | 6.8 | pKd | None | 6.8 | Binding | Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 17092771 | ||
2910 | 8403 | 0 | None | - | 1 | Human | 6.8 | pKd | None | 6.8 | Binding | Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 17092771 | ||
DB07780 | 8403 | 0 | None | - | 1 | Human | 6.8 | pKd | None | 6.8 | Binding | Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 17092771 | ||
2911 | 8404 | 0 | None | - | 1 | Human | 7.3 | pKd | None | 7.3 | Binding | Guide to Pharmacology | 302 | 9 | 2 | 2 | 4.5 | C/C(=C/CC/C(=C\COP(=O)(O)O)/C)/CCC=C(C)C | 17092771 | ||
6440220 | 8404 | 0 | None | - | 1 | Human | 7.3 | pKd | None | 7.3 | Binding | Guide to Pharmacology | 302 | 9 | 2 | 2 | 4.5 | C/C(=C/CC/C(=C\COP(=O)(O)O)/C)/CCC=C(C)C | 17092771 | ||
None | 223155 | 0 | 35S-GTPGammaS | -38 | 3 | Human | 6.6 | pKi | = | 6.6 | Binding | PDSP KiDatabase | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)O)O | None | ||
None | 223156 | 0 | 35S-GTPGammaS | -125 | 3 | Human | 5.3 | pKi | = | 5.3 | Binding | PDSP KiDatabase | 252 | 4 | 0 | 4 | 3.8 | COP(=O)(OC)SC1=CC=C(C=C1)Cl | None | ||
10051843 | 8211 | 2 | None | 15 | 2 | Human | 6.3 | pKi | = | 6.3 | Binding | Guide to Pharmacology | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 11562440 | ||
10051843 | 8211 | 2 | None | 15 | 2 | Human | 6.3 | pKi | = | 6.3 | Binding | Guide to Pharmacology | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 14500756 | ||
2916 | 8211 | 2 | None | 15 | 2 | Human | 6.3 | pKi | = | 6.3 | Binding | Guide to Pharmacology | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 11562440 | ||
2916 | 8211 | 2 | None | 15 | 2 | Human | 6.3 | pKi | = | 6.3 | Binding | Guide to Pharmacology | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 14500756 | ||
CHEMBL191055 | 8211 | 2 | None | 15 | 2 | Human | 6.3 | pKi | = | 6.3 | Binding | Guide to Pharmacology | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 11562440 | ||
CHEMBL191055 | 8211 | 2 | None | 15 | 2 | Human | 6.3 | pKi | = | 6.3 | Binding | Guide to Pharmacology | 504 | 20 | 3 | 8 | 4.4 | CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC)COP(=O)(OP(=O)(O)O)O | 14500756 | ||
10282223 | 10782 | 4 | None | 2 | 2 | Human | 6.4 | pKi | = | 6.4 | Binding | Guide to Pharmacology | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1ccccc1)COP(=O)(O)O | 11723223 | ||
2909 | 10782 | 4 | None | 2 | 2 | Human | 6.4 | pKi | = | 6.4 | Binding | Guide to Pharmacology | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1ccccc1)COP(=O)(O)O | 11723223 | ||
CHEMBL327240 | 10782 | 4 | None | 2 | 2 | Human | 6.4 | pKi | = | 6.4 | Binding | Guide to Pharmacology | 601 | 24 | 3 | 4 | 8.4 | CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](Cc1ccc(cc1)OCc1ccccc1)COP(=O)(O)O | 11723223 | ||
10367662 | 8967 | 91 | None | 1 | 3 | Human | 6.4 | pKi | = | 6.4 | Binding | Guide to Pharmacology | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 14500756 | ||
2907 | 8967 | 91 | None | 1 | 3 | Human | 6.4 | pKi | = | 6.4 | Binding | Guide to Pharmacology | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 14500756 | ||
CHEMBL361501 | 8967 | 91 | None | 1 | 3 | Human | 6.4 | pKi | = | 6.4 | Binding | Guide to Pharmacology | 474 | 9 | 2 | 6 | 6.3 | OC(=O)CCSCc1ccc(cc1)c1onc(c1NC(=O)OC(c1ccccc1Cl)C)C | 14500756 | ||
1550836 | 8238 | 0 | None | - | 1 | Human | 7.1 | pKi | = | 7.1 | Binding | Guide to Pharmacology | 264 | 12 | 0 | 4 | 2.8 | CCCCCCCCCCCCOP(=O)([O-])[O-] | 12695531 | ||
4031 | 8238 | 0 | None | - | 1 | Human | 7.1 | pKi | = | 7.1 | Binding | Guide to Pharmacology | 264 | 12 | 0 | 4 | 2.8 | CCCCCCCCCCCCOP(=O)([O-])[O-] | 12695531 | ||
10468943 | 8239 | 5 | None | 1 | 2 | Mouse | 7.9 | pKi | = | 7.9 | Binding | Guide to Pharmacology | 282 | 12 | 2 | 2 | 4.1 | CCCCCCCCCCCCOP(=S)(O)O | 16033271 | ||
6990 | 8239 | 5 | None | 1 | 2 | Mouse | 7.9 | pKi | = | 7.9 | Binding | Guide to Pharmacology | 282 | 12 | 2 | 2 | 4.1 | CCCCCCCCCCCCOP(=S)(O)O | 16033271 | ||
CHEMBL191365 | 8239 | 5 | None | 1 | 2 | Mouse | 7.9 | pKi | = | 7.9 | Binding | Guide to Pharmacology | 282 | 12 | 2 | 2 | 4.1 | CCCCCCCCCCCCOP(=S)(O)O | 16033271 |