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Ligand source activities (1 row/activity)

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

CHEMBL1090796	8023	None	0	Human	Binding	IC50	=	13.10	7.88	-	4	Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptor expressed in HEK293T cells after 60 mins by scintillation counting	ChEMBL	482.2	10	4	5	3.93	C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(C(=O)CCc2ccc(-c3ccccc3)cc2)cc1	https://dx.doi.org/10.1016/j.bmcl.2010.02.098
CHEMBL1090829	8033	None	0	Human	Binding	IC50	=	6.50	8.19	-	3	Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptor expressed in HEK293T cells after 60 mins by scintillation counting	ChEMBL	561.2	10	4	5	5.67	C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)c[nH]1	https://dx.doi.org/10.1016/j.bmcl.2010.02.098
CHEMBL1093429	8413	None	0	Human	Binding	IC50	=	3.40	8.47	-	4	Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptor expressed in HEK293T cells after 60 mins by scintillation counting	ChEMBL	538.1	10	4	5	4.76	C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)c(C(F)(F)F)c1	https://dx.doi.org/10.1016/j.bmcl.2010.02.098
CHEMBL1093823	8466	None	0	Human	Binding	IC50	=	4.40	8.36	-	4	Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptor expressed in HEK293T cells after 60 mins by scintillation counting	ChEMBL	547.1	9	4	5	5.63	C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)c[nH]1	https://dx.doi.org/10.1016/j.bmcl.2010.02.098
CHEMBL1095833	8719	None	24	Human	Binding	IC50	=	1956.00	5.71	-	4	Displacement of [33P]S1P from human recombinant S1P4 receptor expressed in CHO cells by scintillation counting	ChEMBL	460.1	8	2	6	4.27	CCC/N=C1\S/C(=C\c2ccc(OC[C@@H](O)CO)c(Cl)c2)C(=O)N1c1ccccc1C	https://dx.doi.org/10.1021/jm100181s
CHEMBL112655	9627	None	0	Human	Binding	IC50	=	140.00	6.85	-	4	Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranes	ChEMBL	371.2	13	4	3	3.39	CCCCCCCCc1ccc(CCC(N)C(O)CP(=O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.02.106
CHEMBL113344	9736	None	0	Human	Binding	IC50	=	23.00	7.64	-	4	Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranes	ChEMBL	371.2	13	4	3	3.74	CCCCCCCCc1ccc(CCC(N)CC(O)P(=O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.02.106
CHEMBL114584	9939	None	2	Human	Binding	IC50	=	210.00	6.68	-	4	Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranes	ChEMBL	385.2	14	4	3	3.78	CCCCCCCCc1ccc(CCC(N)(CO)CCP(=O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.02.106
CHEMBL114976	10016	None	0	Human	Binding	IC50	=	500.00	6.30	-	4	Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranes	ChEMBL	371.2	13	4	3	3.74	CCCCCCCCc1ccc(CC[C@H](N)C[C@@H](O)P(=O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.02.106
CHEMBL115554	10108	None	0	Human	Binding	IC50	=	16.00	7.80	-	4	Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranes	ChEMBL	371.2	13	4	3	3.74	CCCCCCCCc1ccc(CC[C@@H](N)C[C@@H](O)P(=O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.02.106
CHEMBL115713	10138	None	2	Human	Binding	IC50	=	16.00	7.80	-	4	Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand	ChEMBL	371.2	13	4	3	3.74	CCCCCCCCc1ccc(CC[C@@H](N)C[C@H](O)P(=O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.04.069
CHEMBL115713	10138	None	2	Human	Binding	IC50	=	280.00	6.55	-	4	Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranes	ChEMBL	371.2	13	4	3	3.74	CCCCCCCCc1ccc(CC[C@@H](N)C[C@H](O)P(=O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.02.106
CHEMBL115714	10139	None	0	Human	Binding	IC50	=	880.00	6.06	-	4	Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranes	ChEMBL	371.2	13	4	3	3.74	CCCCCCCCc1ccc(CC[C@H](N)C[C@H](O)P(=O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.02.106
CHEMBL115738	10144	None	0	Human	Binding	IC50	=	800.00	6.10	-	4	Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand	ChEMBL	363.3	19	3	2	5.63	CCCCCCCCCCCCCCCCNCCCP(=O)(O)O	https://dx.doi.org/10.1016/j.bmcl.2004.04.069
CHEMBL1160958	10248	None	0	Human	Binding	IC50	=	900.00	6.05	-	4	Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand	ChEMBL	339.2	14	3	3	4.76	CCCCCCCCCc1ccc(CNCCCP(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.04.069
CHEMBL116140	10273	None	0	Human	Binding	IC50	=	1400.00	5.85	-	4	Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand	ChEMBL	335.2	14	3	3	3.90	CCCCCCCCCc1ccc(CNCC(O)CC(=O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.04.069
CHEMBL1161691	10294	None	0	Human	Binding	IC50	=	15.00	7.82	-	5	Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 4 expressed on CHO cell membranes	ChEMBL	389.2	14	5	6	2.62	CCCCCCCCc1ccc(CCC(N)(CO)CO[PH](O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.07.049
CHEMBL117031	10646	None	0	Human	Binding	IC50	=	94.00	7.03	-	4	Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand	ChEMBL	355.2	14	3	2	4.63	NC(CCCCCCCCCCc1ccccc1)CCP(=O)(O)O	https://dx.doi.org/10.1016/j.bmcl.2004.04.069
CHEMBL117130	10754	None	0	Human	Binding	IC50	=	15.00	7.82	-	4	Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand	ChEMBL	373.2	13	4	4	3.28	CCCCCCCCc1ccc(CCC(N)(CO)OP(=O)(O)O)cc1	https://dx.doi.org/10.1016/j.bmcl.2004.04.069
CHEMBL117723	11057	None	0	Human	Binding	IC50	=	80.00	7.10	-	6	Displacement of [33P]sphingosine 1 phosphate from human S1P4 receptor expressed in CHO cells	ChEMBL	465.1	15	3	4	4.85	CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC	https://dx.doi.org/10.1021/jm0492507

Showing 1 to 20 of 220 entries

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

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Ligand source activities (1 row/activity)