GPCRdb

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Ligand source activities (1 row/activity)

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

10,10-difluoro TXA₂	1	3H-PAF	0	Human	Binding	pKi	=	130.00	6.89	8	8	-	PDSP KiDatabase	386.2	12	2	3	4.72	CCCCC[C@H](O)/C=C/[C@H]1C[C@@H]2O[C@H]([C@@H]1C/C=C\CCCC(=O)O)C2(F)F	-
10,10-difluoro TXA₂	1	3H-PAF	0	Human	Binding	pKi	=	16.90	7.77	8	8	-	PDSP KiDatabase	386.2	12	2	3	4.72	CCCCC[C@H](O)/C=C/[C@H]1C[C@@H]2O[C@H]([C@@H]1C/C=C\CCCC(=O)O)C2(F)F	-
10,10-difluoro TXA₂	1	3H-PAF	0	Human	Binding	pKi	=	129.00	6.89	8	8	-	PDSP KiDatabase	386.2	12	2	3	4.72	CCCCC[C@H](O)/C=C/[C@H]1C[C@@H]2O[C@H]([C@@H]1C/C=C\CCCC(=O)O)C2(F)F	-
10,10-difluoro TXA₂	1	3H-PAF	0	Human	Binding	pKi	=	38.60	7.41	8	8	-	PDSP KiDatabase	386.2	12	2	3	4.72	CCCCC[C@H](O)/C=C/[C@H]1C[C@@H]2O[C@H]([C@@H]1C/C=C\CCCC(=O)O)C2(F)F	-
10,10-difluoro TXA₂	1	3H-PAF	0	Human	Binding	pKi	=	1.40	8.85	8	8	-	PDSP KiDatabase	386.2	12	2	3	4.72	CCCCC[C@H](O)/C=C/[C@H]1C[C@@H]2O[C@H]([C@@H]1C/C=C\CCCC(=O)O)C2(F)F	-
10,10-difluoro TXA₂	1	3H-PAF	0	Human	Binding	pKi	=	1.80	8.74	8	8	-	PDSP KiDatabase	386.2	12	2	3	4.72	CCCCC[C@H](O)/C=C/[C@H]1C[C@@H]2O[C@H]([C@@H]1C/C=C\CCCC(=O)O)C2(F)F	-
10-OBn-7α-F-gingkolide B	2	None	0	Mouse	Binding	pKi	None	-	7.00	-	1	Unclassified	Guide to Pharmacology	532.2	3	2	10	0.80	CC1C(=O)O[C@H]2C(O)C34C5OC(=O)[C@@]3(OC3OC(=O)[C@H](OCc6ccccc6)C34C(C(C)(C)C)[C@@H]5F)[C@@]12O	https://pubmed.ncbi.nlm.nih.gov/12570381
10-OBn-epi-ginkgolide C	3	None	0	Mouse	Binding	pKi	None	-	6.20	-	1	Unclassified	Guide to Pharmacology	530.2	3	3	11	-0.17	CC1C(=O)O[C@H]2C(O)C34C5OC(=O)[C@@]3(OC3OC(=O)[C@H](OCc6ccccc6)C34C(C(C)(C)C)[C@@H]5O)[C@@]12O	https://pubmed.ncbi.nlm.nih.gov/12570381
10-OBn-ginkgolide B	4	None	0	Mouse	Binding	pKi	None	-	6.90	-	1	Unclassified	Guide to Pharmacology	514.2	3	2	10	0.85	CC1C(=O)O[C@H]2C(O)C34C5CC(C(C)(C)C)C36C(OC(=O)[C@@H]6OCc3ccccc3)O[C@]4(C(=O)O5)[C@@]12O	https://pubmed.ncbi.nlm.nih.gov/12570381
10-OBn-ginkgolide C	5	None	0	Mouse	Binding	pKi	None	-	5.80	-	1	Unclassified	Guide to Pharmacology	530.2	3	3	11	-0.17	CC1C(=O)O[C@H]2C(O)C34C5OC(=O)[C@@]3(OC3OC(=O)[C@H](OCc6ccccc6)C34C(C(C)(C)C)[C@H]5O)[C@@]12O	https://pubmed.ncbi.nlm.nih.gov/12570381
7α-Cl-ginkgolide B	168	None	0	Mouse	Binding	pKi	None	-	7.00	-	1	Unclassified	Guide to Pharmacology	458.1	0	3	10	-1.15	CC1C(=O)O[C@H]2C(O)C34C5OC(=O)[C@@]3(OC3OC(=O)[C@H](O)C34C(C(C)(C)C)C5Cl)[C@@]12O	https://pubmed.ncbi.nlm.nih.gov/12570381
7α-F-ginkgolide B	169	None	0	Mouse	Binding	pKi	None	-	6.00	-	1	Unclassified	Guide to Pharmacology	442.1	0	3	10	-1.42	CC1C(=O)O[C@H]2C(O)C34C5OC(=O)[C@@]3(OC3OC(=O)[C@H](O)C34C(C(C)(C)C)C5F)[C@@]12O	https://pubmed.ncbi.nlm.nih.gov/12570381
7α-N₃-ginkgolide B	174	None	0	Mouse	Binding	pKi	None	-	6.30	-	1	Unclassified	Guide to Pharmacology	-	-	-	-	-	[N-]=[N]=N[C@H]1C(C(C)(C)C)C23C45C1OC(=O)[C@@]5(OC2OC(=O)[C@@H]3O)[C@@]1([C@H](C4O)OC(=O)C1C)O	https://pubmed.ncbi.nlm.nih.gov/12570381
7α-NH₂-ginkgolide B	173	None	0	Mouse	Binding	pKi	None	-	5.10	-	1	Unclassified	Guide to Pharmacology	439.1	0	4	11	-2.43	CC1C(=O)O[C@H]2C(O)C34C5OC(=O)[C@@]3(OC3OC(=O)[C@H](O)C34C(C(C)(C)C)[C@@H]5N)[C@@]12O	https://pubmed.ncbi.nlm.nih.gov/12570381
7α-NHEt-ginkgolide B	171	None	0	Mouse	Binding	pKi	None	-	5.80	-	1	Unclassified	Guide to Pharmacology	467.2	2	4	11	-1.78	CCN[C@H]1C(C(C)(C)C)C23C(OC(=O)[C@@H]2O)O[C@@]24C(=O)OC1C32C(O)[C@@H]1OC(=O)C(C)[C@@]14O	https://pubmed.ncbi.nlm.nih.gov/12570381
7α-NHMe-ginkgolide B	172	None	0	Mouse	Binding	pKi	None	-	6.20	-	1	Unclassified	Guide to Pharmacology	453.2	1	4	11	-2.17	CN[C@H]1C(C(C)(C)C)C23C(OC(=O)[C@@H]2O)O[C@@]24C(=O)OC1C32C(O)[C@@H]1OC(=O)C(C)[C@@]14O	https://pubmed.ncbi.nlm.nih.gov/12570381
7α-OAc-ginkgolide B	175	None	0	Mouse	Binding	pKi	None	-	5.10	-	1	Unclassified	Guide to Pharmacology	482.1	1	3	12	-1.83	CC(=O)OC1C(C(C)(C)C)C23C(OC(=O)[C@@H]2O)O[C@@]24C(=O)OC1C32C(O)[C@@H]1OC(=O)C(C)[C@@]14O	https://pubmed.ncbi.nlm.nih.gov/12570381
7α-OCOCH₂Ph-ginkgolide B	176	None	0	Mouse	Binding	pKi	None	-	5.60	-	1	Unclassified	Guide to Pharmacology	558.2	3	3	12	-0.60	CC1C(=O)O[C@H]2C(O)C34C5OC(=O)[C@@]3(OC3OC(=O)[C@H](O)C34C(C(C)(C)C)[C@@H]5OC(=O)Cc3ccccc3)[C@@]12O	https://pubmed.ncbi.nlm.nih.gov/12570381
7-epi-ginkgolide C	180	None	0	Mouse	Binding	pKi	None	-	5.40	-	1	Unclassified	Guide to Pharmacology	440.1	0	4	11	-2.40	CC1C(=O)O[C@H]2C(O)C34C5OC(=O)[C@@]3(OC3OC(=O)[C@H](O)C34C(C(C)(C)C)[C@H]5O)[C@@]12O	https://pubmed.ncbi.nlm.nih.gov/12570381
ABT-299	230	None	3	Human	Binding	pKi	None	-	9.50	6	2	Unclassified	Guide to Pharmacology	618.1	6	0	7	2.62	CC(=O)OC[n+]1cccc([C@H]2SCc3c(C(=O)c4cn(C(=O)N(C)C)c5cc(-c6ccc(F)cc6)ccc45)ccn32)c1.[Cl-]	https://pubmed.ncbi.nlm.nih.gov/8667228

Showing 1 to 20 of 832 entries

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

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Ligand source activities (1 row/activity)