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Ligand source activities (1 row/activity)

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Ligands (move mouse cursor over ligand name to see structure)					Receptor		Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found		Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found

Ligands (move mouse cursor over ligand name to see structure)					Receptor	Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found	Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found
	445643	97442	None	46	Human	Functional	pAC50	=	5	5.0	-1	7	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	803	7	3	12	4.6	C=CC[C@@H]1/C=C(\C)C[C@H](C)C[C@H](OC)[C@H]2O[C@@](O)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@H](/C(C)=C/[C@@H]3CC[C@@H](O)[C@H](OC)C3)[C@H](C)[C@@H](O)CC1=O)[C@H](C)C[C@@H]2OC	10.1038/s41467-023-40064-9
	CHEMBL269732	97442	None	46	Human	Functional	pAC50	=	5	5.0	-1	7	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	803	7	3	12	4.6	C=CC[C@@H]1/C=C(\C)C[C@H](C)C[C@H](OC)[C@H]2O[C@@](O)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@H](/C(C)=C/[C@@H]3CC[C@@H](O)[C@H](OC)C3)[C@H](C)[C@@H](O)CC1=O)[C@H](C)C[C@@H]2OC	10.1038/s41467-023-40064-9
	2398	954	None	43	Human	Functional	pAC50	=	5.0	5.0	-7413	36	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	4	0	2	4.5	CN(CCCN1c2ccccc2CCc2c1cc(Cl)cc2)C	10.1038/s41467-023-40064-9
	2801	954	None	43	Human	Functional	pAC50	=	5.0	5.0	-7413	36	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	4	0	2	4.5	CN(CCCN1c2ccccc2CCc2c1cc(Cl)cc2)C	10.1038/s41467-023-40064-9
	2801.0	954	None	43	Human	Functional	pAC50	=	5.0	5.0	-7413	36	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	4	0	2	4.5	CN(CCCN1c2ccccc2CCc2c1cc(Cl)cc2)C	10.1038/s41467-023-40064-9
	701	954	None	43	Human	Functional	pAC50	=	5.0	5.0	-7413	36	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	4	0	2	4.5	CN(CCCN1c2ccccc2CCc2c1cc(Cl)cc2)C	10.1038/s41467-023-40064-9
	CHEMBL415	954	None	43	Human	Functional	pAC50	=	5.0	5.0	-7413	36	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	4	0	2	4.5	CN(CCCN1c2ccccc2CCc2c1cc(Cl)cc2)C	10.1038/s41467-023-40064-9
	DB01242	954	None	43	Human	Functional	pAC50	=	5.0	5.0	-7413	36	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	4	0	2	4.5	CN(CCCN1c2ccccc2CCc2c1cc(Cl)cc2)C	10.1038/s41467-023-40064-9
	5022	1651	None	58	Human	Functional	pAC50	=	5.0	5.0	-239	9	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	390	4	1	4	3.2	O=c1[nH]c2c(n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F)cccc2	10.1038/s41467-023-40064-9
	6918248	1651	None	58	Human	Functional	pAC50	=	5.0	5.0	-239	9	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	390	4	1	4	3.2	O=c1[nH]c2c(n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F)cccc2	10.1038/s41467-023-40064-9
	6918248.0	1651	None	58	Human	Functional	pAC50	=	5.0	5.0	-239	9	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	390	4	1	4	3.2	O=c1[nH]c2c(n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F)cccc2	10.1038/s41467-023-40064-9
	8182	1651	None	58	Human	Functional	pAC50	=	5.0	5.0	-239	9	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	390	4	1	4	3.2	O=c1[nH]c2c(n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F)cccc2	10.1038/s41467-023-40064-9
	CHEMBL231068	1651	None	58	Human	Functional	pAC50	=	5.0	5.0	-239	9	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	390	4	1	4	3.2	O=c1[nH]c2c(n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F)cccc2	10.1038/s41467-023-40064-9
	DB04908	1651	None	58	Human	Functional	pAC50	=	5.0	5.0	-239	9	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	390	4	1	4	3.2	O=c1[nH]c2c(n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F)cccc2	10.1038/s41467-023-40064-9
	2247	505	None	55	Human	Functional	pAC50	=	5.0	5.0	-812	42	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	458	8	1	5	5.4	COc1ccc(cc1)CCN1CCC(CC1)Nc1nc2c(n1Cc1ccc(cc1)F)cccc2	10.1038/s41467-023-40064-9
	249	505	None	55	Human	Functional	pAC50	=	5.0	5.0	-812	42	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	458	8	1	5	5.4	COc1ccc(cc1)CCN1CCC(CC1)Nc1nc2c(n1Cc1ccc(cc1)F)cccc2	10.1038/s41467-023-40064-9
	2603	505	None	55	Human	Functional	pAC50	=	5.0	5.0	-812	42	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	458	8	1	5	5.4	COc1ccc(cc1)CCN1CCC(CC1)Nc1nc2c(n1Cc1ccc(cc1)F)cccc2	10.1038/s41467-023-40064-9
	CHEMBL296419	505	None	55	Human	Functional	pAC50	=	5.0	5.0	-812	42	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	458	8	1	5	5.4	COc1ccc(cc1)CCN1CCC(CC1)Nc1nc2c(n1Cc1ccc(cc1)F)cccc2	10.1038/s41467-023-40064-9
	DB00637	505	None	55	Human	Functional	pAC50	=	5.0	5.0	-812	42	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	458	8	1	5	5.4	COc1ccc(cc1)CCN1CCC(CC1)Nc1nc2c(n1Cc1ccc(cc1)F)cccc2	10.1038/s41467-023-40064-9
	2710	84342	None	29	Human	Functional	pAC50	=	5.0	5.0	-25	10	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	300	3	0	2	3.7	CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1	10.1038/s41467-023-40064-9
	2710.0	84342	None	29	Human	Functional	pAC50	=	5.0	5.0	-25	10	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	300	3	0	2	3.7	CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1	10.1038/s41467-023-40064-9
	CHEMBL1889091	84342	None	29	Human	Functional	pAC50	=	5.0	5.0	-25	10	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	300	3	0	2	3.7	CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1	10.1038/s41467-023-40064-9
	CHEMBL22150	84342	None	29	Human	Functional	pAC50	=	5.0	5.0	-25	10	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	300	3	0	2	3.7	CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1	10.1038/s41467-023-40064-9
	DB08936	84342	None	29	Human	Functional	pAC50	=	5.0	5.0	-25	10	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	300	3	0	2	3.7	CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1	10.1038/s41467-023-40064-9
	3351	95055	None	40	Human	Functional	pAC50	=	5.0	5.0	-1	6	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	388	5	0	5	2.8	O=C(COc1ccc(Cl)cc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1	10.1038/s41467-023-40064-9
	CHEMBL254857	95055	None	40	Human	Functional	pAC50	=	5.0	5.0	-1	6	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	388	5	0	5	2.8	O=C(COc1ccc(Cl)cc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1	10.1038/s41467-023-40064-9
	9823820	19173	None	64	Human	Functional	pAC50	=	4.9	4.9	1	2	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	426	6	3	5	4.1	COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O	10.1038/s41467-023-40064-9
	CHEMBL1289601	19173	None	64	Human	Functional	pAC50	=	4.9	4.9	1	2	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	426	6	3	5	4.1	COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O	10.1038/s41467-023-40064-9
	3035016	12598	None	44	Human	Functional	pAC50	=	4.9	4.9	1	3	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	483	3	5	10	0.6	CC(=O)[C@]1(N)Cc2c(O)c3c(c(O)c2[C@@H](O[C@H]2C[C@H](O)[C@H](O)CO2)C1)C(=O)c1ccccc1C3=O	10.1038/s41467-023-40064-9
	CHEMBL1186894	12598	None	44	Human	Functional	pAC50	=	4.9	4.9	1	3	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	483	3	5	10	0.6	CC(=O)[C@]1(N)Cc2c(O)c3c(c(O)c2[C@@H](O[C@H]2C[C@H](O)[C@H](O)CO2)C1)C(=O)c1ccccc1C3=O	10.1038/s41467-023-40064-9
	3627	44143	None	12	Human	Functional	pAC50	=	4.9	4.9	-162	9	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	314	3	0	2	4.1	CN1CCCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1	10.1038/s41467-023-40064-9
	CHEMBL1515447	44143	None	12	Human	Functional	pAC50	=	4.9	4.9	-162	9	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	314	3	0	2	4.1	CN1CCCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1	10.1038/s41467-023-40064-9
	196122	112651	None	39	Human	Functional	pAC50	=	4.9	4.9	-1	4	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	478	13	1	6	4.5	CCOC1O[C@H]([C@@H](COCc2ccccc2)OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1O	10.1038/s41467-023-40064-9
	CHEMBL3301681	112651	None	39	Human	Functional	pAC50	=	4.9	4.9	-1	4	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	478	13	1	6	4.5	CCOC1O[C@H]([C@@H](COCc2ccccc2)OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1O	10.1038/s41467-023-40064-9
	98941	46964	None	13	Human	Functional	pAC50	=	4.9	4.9	-58	11	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	457	7	0	4	6.3	COc1ccc2c(c1)OC(C)(C)C(c1ccccc1)C2c1ccc(OCCN2CCCC2)cc1	10.1038/s41467-023-40064-9
	CHEMBL154126	46964	None	13	Human	Functional	pAC50	=	4.9	4.9	-58	11	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	457	7	0	4	6.3	COc1ccc2c(c1)OC(C)(C)C(c1ccccc1)C2c1ccc(OCCN2CCCC2)cc1	10.1038/s41467-023-40064-9
	4150	788	None	26	Human	Functional	pAC50	=	5.9	5.9	-19	16	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	6	2	2	5.8	CCCCCc1cc(O)c(c(c1)O)[C@@H]1C=C(C)CC[C@H]1C(=C)C	10.1038/s41467-023-40064-9
	5288	788	None	26	Human	Functional	pAC50	=	5.9	5.9	-19	16	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	6	2	2	5.8	CCCCCc1cc(O)c(c(c1)O)[C@@H]1C=C(C)CC[C@H]1C(=C)C	10.1038/s41467-023-40064-9
	644019	788	None	26	Human	Functional	pAC50	=	5.9	5.9	-19	16	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	6	2	2	5.8	CCCCCc1cc(O)c(c(c1)O)[C@@H]1C=C(C)CC[C@H]1C(=C)C	10.1038/s41467-023-40064-9
	644019.0	788	None	26	Human	Functional	pAC50	=	5.9	5.9	-19	16	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	6	2	2	5.8	CCCCCc1cc(O)c(c(c1)O)[C@@H]1C=C(C)CC[C@H]1C(=C)C	10.1038/s41467-023-40064-9
	CHEMBL190461	788	None	26	Human	Functional	pAC50	=	5.9	5.9	-19	16	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	6	2	2	5.8	CCCCCc1cc(O)c(c(c1)O)[C@@H]1C=C(C)CC[C@H]1C(=C)C	10.1038/s41467-023-40064-9
	DB09061	788	None	26	Human	Functional	pAC50	=	5.9	5.9	-19	16	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	6	2	2	5.8	CCCCCc1cc(O)c(c(c1)O)[C@@H]1C=C(C)CC[C@H]1C(=C)C	10.1038/s41467-023-40064-9
	9818306	14424	None	13	Human	Functional	pAC50	=	4.9	4.9	-1	5	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	1	1	3	3.8	CC(=O)Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12	10.1038/s41467-023-40064-9
	CHEMBL1200430	14424	None	13	Human	Functional	pAC50	=	4.9	4.9	-1	5	Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopyAntagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy	ChEMBL	314	1	1	3	3.8	CC(=O)Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12	10.1038/s41467-023-40064-9
	5568	199956	None	21	Human	Functional	pAC50	=	4.9	4.9	-4365	13	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	352	4	0	3	5.3	CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21	10.1038/s41467-023-40064-9
	5568.0	199956	None	21	Human	Functional	pAC50	=	4.9	4.9	-4365	13	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	352	4	0	3	5.3	CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21	10.1038/s41467-023-40064-9
	66069	199956	None	21	Human	Functional	pAC50	=	4.9	4.9	-4365	13	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	352	4	0	3	5.3	CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21	10.1038/s41467-023-40064-9
	CHEMBL1201102	199956	None	21	Human	Functional	pAC50	=	4.9	4.9	-4365	13	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	352	4	0	3	5.3	CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21	10.1038/s41467-023-40064-9
	CHEMBL570	199956	None	21	Human	Functional	pAC50	=	4.9	4.9	-4365	13	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	352	4	0	3	5.3	CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21	10.1038/s41467-023-40064-9
	DB00508	199956	None	21	Human	Functional	pAC50	=	4.9	4.9	-4365	13	Agonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopyAgonist activity at human TBXA2R in an in vitro cell-based assay (CRO assay) measured by fluorescence spectroscopy	ChEMBL	352	4	0	3	5.3	CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21	10.1038/s41467-023-40064-9

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Ligands (move mouse cursor over ligand name to see structure)					Receptor		Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found		Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found

Ligands (move mouse cursor over ligand name to see structure)					Receptor	Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found	Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found
	31508	97271	None	31	Human	Binding	pAC50	=	5.0	5.0	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	278	2	0	3	4.0	Cc1ccc2c(-c3ccccc3)nc(=O)n(C(C)C)c2c1	10.1038/s41467-023-40064-9
	CHEMBL268501	97271	None	31	Human	Binding	pAC50	=	5.0	5.0	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	278	2	0	3	4.0	Cc1ccc2c(-c3ccccc3)nc(=O)n(C(C)C)c2c1	10.1038/s41467-023-40064-9
	91610	141440	None	61	Human	Binding	pAC50	=	5.0	5.0	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	527	7	2	6	3.5	COc1ccc2c(c1)C(=O)N(CCc1ccc(S(=O)(=O)NC(=O)NC3CCCCC3)cc1)C(=O)C2(C)C	10.1038/s41467-023-40064-9
	CHEMBL383634	141440	None	61	Human	Binding	pAC50	=	5.0	5.0	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	527	7	2	6	3.5	COc1ccc2c(c1)C(=O)N(CCc1ccc(S(=O)(=O)NC(=O)NC3CCCCC3)cc1)C(=O)C2(C)C	10.1038/s41467-023-40064-9
	5029	15552	None	54	Human	Binding	pAC50	=	4.9	4.9	-	4	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	359	8	1	5	3.0	COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C	10.1038/s41467-023-40064-9
	CHEMBL1219	15552	None	54	Human	Binding	pAC50	=	4.9	4.9	-	4	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	359	8	1	5	3.0	COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C	10.1038/s41467-023-40064-9
	135564886	14499	None	5	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	752	14	1	6	8.7	CC1(C)C(/C=C/C=C/C=C/C=C2\N(CCCCS(=O)(=O)O)c3ccc4ccccc4c3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21	10.1038/s41467-023-40064-9
	135673376	14499	None	5	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	752	14	1	6	8.7	CC1(C)C(/C=C/C=C/C=C/C=C2\N(CCCCS(=O)(=O)O)c3ccc4ccccc4c3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21	10.1038/s41467-023-40064-9
	137157436	14499	None	5	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	752	14	1	6	8.7	CC1(C)C(/C=C/C=C/C=C/C=C2\N(CCCCS(=O)(=O)O)c3ccc4ccccc4c3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21	10.1038/s41467-023-40064-9
	145948239	14499	None	5	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	752	14	1	6	8.7	CC1(C)C(/C=C/C=C/C=C/C=C2\N(CCCCS(=O)(=O)O)c3ccc4ccccc4c3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21	10.1038/s41467-023-40064-9
	71587099	14499	None	5	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	752	14	1	6	8.7	CC1(C)C(/C=C/C=C/C=C/C=C2\N(CCCCS(=O)(=O)O)c3ccc4ccccc4c3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21	10.1038/s41467-023-40064-9
	CHEMBL1201304	14499	None	5	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	752	14	1	6	8.7	CC1(C)C(/C=C/C=C/C=C/C=C2\N(CCCCS(=O)(=O)O)c3ccc4ccccc4c3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21	10.1038/s41467-023-40064-9
	2179	167616	None	49	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	393	5	2	5	4.5	COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12	10.1038/s41467-023-40064-9
	CHEMBL1256655	167616	None	49	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	393	5	2	5	4.5	COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12	10.1038/s41467-023-40064-9
	CHEMBL43	167616	None	49	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	393	5	2	5	4.5	COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12	10.1038/s41467-023-40064-9
	53232	188732	None	57	Human	Binding	pAC50	=	4.9	4.9	-	2	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	404	6	1	5	4.2	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21	10.1038/s41467-023-40064-9
	CHEMBL503	188732	None	57	Human	Binding	pAC50	=	4.9	4.9	-	2	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	404	6	1	5	4.2	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21	10.1038/s41467-023-40064-9
	5282219	35878	None	48	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	450	12	1	5	5.7	CC(C)=CCOc1ccc(/C=C/C(=O)c2ccc(OCC=C(C)C)cc2OCC(=O)O)cc1	10.1038/s41467-023-40064-9
	CHEMBL1441961	35878	None	48	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	450	12	1	5	5.7	CC(C)=CCOc1ccc(/C=C/C(=O)c2ccc(OCC=C(C)C)cc2OCC(=O)O)cc1	10.1038/s41467-023-40064-9
	4614	5393	None	62	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	293	5	1	3	4.0	O=C(O)CCc1nc(-c2ccccc2)c(-c2ccccc2)o1	10.1038/s41467-023-40064-9
	CHEMBL1071	5393	None	62	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	293	5	1	3	4.0	O=C(O)CCc1nc(-c2ccccc2)c(-c2ccccc2)o1	10.1038/s41467-023-40064-9
	10531	1420	None	13	Human	Binding	pAC50	=	4.9	4.9	-	30	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	583	4	3	6	2.1	CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c1c2ccc3)C(=O)N[C@]1(C)O[C@@]2(N(C1=O)[C@@H](Cc1ccccc1)C(=O)N1[C@H]2CCC1)O	10.1038/s41467-023-40064-9
	10531.0	1420	None	13	Human	Binding	pAC50	=	4.9	4.9	-	30	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	583	4	3	6	2.1	CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c1c2ccc3)C(=O)N[C@]1(C)O[C@@]2(N(C1=O)[C@@H](Cc1ccccc1)C(=O)N1[C@H]2CCC1)O	10.1038/s41467-023-40064-9
	121	1420	None	13	Human	Binding	pAC50	=	4.9	4.9	-	30	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	583	4	3	6	2.1	CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c1c2ccc3)C(=O)N[C@]1(C)O[C@@]2(N(C1=O)[C@@H](Cc1ccccc1)C(=O)N1[C@H]2CCC1)O	10.1038/s41467-023-40064-9
	888	1420	None	13	Human	Binding	pAC50	=	4.9	4.9	-	30	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	583	4	3	6	2.1	CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c1c2ccc3)C(=O)N[C@]1(C)O[C@@]2(N(C1=O)[C@@H](Cc1ccccc1)C(=O)N1[C@H]2CCC1)O	10.1038/s41467-023-40064-9
	CHEMBL1732	1420	None	13	Human	Binding	pAC50	=	4.9	4.9	-	30	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	583	4	3	6	2.1	CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c1c2ccc3)C(=O)N[C@]1(C)O[C@@]2(N(C1=O)[C@@H](Cc1ccccc1)C(=O)N1[C@H]2CCC1)O	10.1038/s41467-023-40064-9
	DB00320	1420	None	13	Human	Binding	pAC50	=	4.9	4.9	-	30	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	583	4	3	6	2.1	CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c1c2ccc3)C(=O)N[C@]1(C)O[C@@]2(N(C1=O)[C@@H](Cc1ccccc1)C(=O)N1[C@H]2CCC1)O	10.1038/s41467-023-40064-9
	5353627	84575	None	8	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	411	8	3	4	4.6	CC(C)n1c(/C=C/C(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c2ccccc21	10.1038/s41467-023-40064-9
	CHEMBL2220442	84575	None	8	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	411	8	3	4	4.6	CC(C)n1c(/C=C/C(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c2ccccc21	10.1038/s41467-023-40064-9
	11980903	14498	None	13	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	382	4	0	2	5.3	Cc1cc(/C=C/c2ccc3cc(N(C)C)ccc3[n+]2C)c(C)n1-c1ccccc1	10.1038/s41467-023-40064-9
	22526	14498	None	13	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	382	4	0	2	5.3	Cc1cc(/C=C/c2ccc3cc(N(C)C)ccc3[n+]2C)c(C)n1-c1ccccc1	10.1038/s41467-023-40064-9
	5281035	14498	None	13	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	382	4	0	2	5.3	Cc1cc(/C=C/c2ccc3cc(N(C)C)ccc3[n+]2C)c(C)n1-c1ccccc1	10.1038/s41467-023-40064-9
	CHEMBL1201303	14498	None	13	Human	Binding	pAC50	=	4.9	4.9	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	382	4	0	2	5.3	Cc1cc(/C=C/c2ccc3cc(N(C)C)ccc3[n+]2C)c(C)n1-c1ccccc1	10.1038/s41467-023-40064-9
	5991	206377	None	46	Human	Binding	pAC50	=	4.8	4.8	-	5	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	296	0	2	2	3.6	C#C[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@@]21C	10.1038/s41467-023-40064-9
	CHEMBL691	206377	None	46	Human	Binding	pAC50	=	4.8	4.8	-	5	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	296	0	2	2	3.6	C#C[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@@]21C	10.1038/s41467-023-40064-9
	445643	97442	None	46	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	803	7	3	12	4.6	C=CC[C@@H]1/C=C(\C)C[C@H](C)C[C@H](OC)[C@H]2O[C@@](O)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@H](/C(C)=C/[C@@H]3CC[C@@H](O)[C@H](OC)C3)[C@H](C)[C@@H](O)CC1=O)[C@H](C)C[C@@H]2OC	10.1038/s41467-023-40064-9
	CHEMBL269732	97442	None	46	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	803	7	3	12	4.6	C=CC[C@@H]1/C=C(\C)C[C@H](C)C[C@H](OC)[C@H]2O[C@@](O)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@H](/C(C)=C/[C@@H]3CC[C@@H](O)[C@H](OC)C3)[C@H](C)[C@@H](O)CC1=O)[C@H](C)C[C@@H]2OC	10.1038/s41467-023-40064-9
	2812	4781	None	63	Human	Binding	pAC50	=	4.8	4.8	-	34	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	344	4	0	2	5.4	Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1	10.1038/s41467-023-40064-9
	CHEMBL104	4781	None	63	Human	Binding	pAC50	=	4.8	4.8	-	34	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	344	4	0	2	5.4	Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1	10.1038/s41467-023-40064-9
	54454	5260	None	48	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	418	6	1	5	4.6	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21	10.1038/s41467-023-40064-9
	CHEMBL1064	5260	None	48	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	418	6	1	5	4.6	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21	10.1038/s41467-023-40064-9
	236702	45744	None	44	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	434	3	2	6	2.5	CC(=O)OCC(=O)[C@@]1(O)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C	10.1038/s41467-023-40064-9
	CHEMBL1530428	45744	None	44	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	434	3	2	6	2.5	CC(=O)OCC(=O)[C@@]1(O)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C	10.1038/s41467-023-40064-9
	2194	63103	None	64	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	240	2	0	4	4.2	COc1ccc(-c2cc(=S)ss2)cc1	10.1038/s41467-023-40064-9
	CHEMBL178862	63103	None	64	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	240	2	0	4	4.2	COc1ccc(-c2cc(=S)ss2)cc1	10.1038/s41467-023-40064-9
	2880	98061	None	34	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	310	5	0	3	4.6	C=C(c1ccccc1OCc1cccc(Cl)c1)n1ccnc1	10.1038/s41467-023-40064-9
	CHEMBL27289	98061	None	34	Human	Binding	pAC50	=	4.8	4.8	-	0	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	310	5	0	3	4.6	C=C(c1ccccc1OCc1cccc(Cl)c1)n1ccnc1	10.1038/s41467-023-40064-9
	216239	23803	None	71	Human	Binding	pAC50	=	4.8	4.8	-	7	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	464	5	3	4	5.6	CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1	10.1038/s41467-023-40064-9
	CHEMBL1200485	23803	None	71	Human	Binding	pAC50	=	4.8	4.8	-	7	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	464	5	3	4	5.6	CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1	10.1038/s41467-023-40064-9
	CHEMBL1336	23803	None	71	Human	Binding	pAC50	=	4.8	4.8	-	7	Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assayBinding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay	ChEMBL	464	5	3	4	5.6	CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1	10.1038/s41467-023-40064-9

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Ligand source activities (1 row/activity)