Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 10567 | 1837 | None | 0 | Human | Functional | pEC50 | = | 5.9 | 5.9 | 1 | 3 | Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin. |
Guide to Pharmacology | None | None | None | None | 28900043 | ||||
| 145996510 | 1837 | None | 0 | Human | Functional | pEC50 | = | 5.9 | 5.9 | 1 | 3 | Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin. |
Guide to Pharmacology | None | None | None | None | 28900043 | ||||
| 10568 | 1838 | None | 0 | Human | Functional | pEC50 | = | 6.8 | 6.8 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 31675498 | ||||
| 145996511 | 1838 | None | 0 | Human | Functional | pEC50 | = | 6.8 | 6.8 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 31675498 | ||||
Showing 1 to 4 of 4 entries
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| CHEMBL5085657 | 217467 | None | 0 | Human | Binding | pEC50 | = | 5.8 | 5.8 | - | 0 | Activation of human GPR15 stably expressed in CHO cells expressing Aequorin and Galpha16 measured by luminiscence assayActivation of human GPR15 stably expressed in CHO cells expressing Aequorin and Galpha16 measured by luminiscence assay |
ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C)C(C)C)C(C)C | nan | ||||
| CHEMBL5085657 | 217467 | None | 0 | Human | Binding | pEC50 | = | 6.0 | 6.0 | - | 0 | Activation of human GPR15 stably expressed in CHO cells expressing Aequorin measured by luminiscence assayActivation of human GPR15 stably expressed in CHO cells expressing Aequorin measured by luminiscence assay |
ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C)C(C)C)C(C)C | nan | ||||
Showing 1 to 2 of 2 entries