Ligand source activities (1 row/activity)



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Ligands Receptor Assay information Chemical information
Sel. page Common
name		 GPCRdb ID #Vendors Reference
ligand		 Fold selectivity
(Potency)		 # tested GPCRs
(Potency)		 Species p-value
(-log)		 Type Activity
Relation		 Activity
Value		 Assay Type Assay Description Source Mol
weight		 Rot
Bonds		 H don H acc LogP Smiles DOI
10567 8618 0 None 1 3 Human 5.9 pEC50 = 5.9 Functional
Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.
Guide to Pharmacology None None None None 28900043
145996510 8618 0 None 1 3 Human 5.9 pEC50 = 5.9 Functional
Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.
Guide to Pharmacology None None None None 28900043
10568 8619 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 31675498
145996511 8619 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 31675498


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Ligands Receptor Assay information Chemical information
Sel. page Common
name		 GPCRdb ID #Vendors Reference
ligand		 Fold selectivity
(Affinity)		 # tested GPCRs
(Affinity)		 Species p-value
(-log)		 Type Activity
Relation		 Activity
Value		 Assay Type Assay Description Source Mol
weight		 Rot
Bonds		 H don H acc LogP Smiles DOI
CHEMBL5085657 221757 0 None - 0 Human 5.8 pEC50 = 5.8 Binding
Activation of human GPR15 stably expressed in CHO cells expressing Aequorin and Galpha16 measured by luminiscence assayActivation of human GPR15 stably expressed in CHO cells expressing Aequorin and Galpha16 measured by luminiscence assay
ChEMBL None None None CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C)C(C)C)C(C)C nan
CHEMBL5085657 221757 0 None - 0 Human 6.0 pEC50 = 6.0 Binding
Activation of human GPR15 stably expressed in CHO cells expressing Aequorin measured by luminiscence assayActivation of human GPR15 stably expressed in CHO cells expressing Aequorin measured by luminiscence assay
ChEMBL None None None CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C)C(C)C)C(C)C nan