Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 3930 | 2151 | None | 37 | Human | Functional | pEC50 | = | 5.9 | 5.9 | -28 | 3 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 368 | 3 | 1 | 4 | 4.9 | CN1CCN(CC1)c1ccc(cc1)Nc1c2ccccc2nc2c1cccc2 | 10.6019/CHEMBL5442687 | ||
| 540335 | 2151 | None | 37 | Human | Functional | pEC50 | = | 5.9 | 5.9 | -28 | 3 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 368 | 3 | 1 | 4 | 4.9 | CN1CCN(CC1)c1ccc(cc1)Nc1c2ccccc2nc2c1cccc2 | 10.6019/CHEMBL5442687 | ||
| CHEMBL106525 | 2151 | None | 37 | Human | Functional | pEC50 | = | 5.9 | 5.9 | -28 | 3 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 368 | 3 | 1 | 4 | 4.9 | CN1CCN(CC1)c1ccc(cc1)Nc1c2ccccc2nc2c1cccc2 | 10.6019/CHEMBL5442687 | ||
| 104943 | 55402 | None | 31 | Human | Functional | pIC50 | = | 6.0 | 6.0 | -2344 | 5 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 412 | 7 | 1 | 3 | 5.1 | COc1ccccc1CN[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1 | 10.6019/CHEMBL5442687 | ||
| CHEMBL16192 | 55402 | None | 31 | Human | Functional | pIC50 | = | 6.0 | 6.0 | -2344 | 5 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 412 | 7 | 1 | 3 | 5.1 | COc1ccccc1CN[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1 | 10.6019/CHEMBL5442687 | ||
| 6603703 | 208 | None | 8 | Human | Functional | pIC50 | = | 5.8 | 5.8 | -478 | 18 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 329 | 2 | 3 | 4 | 3.3 | NC[C@@H]1O[C@@H](Cc2c1ccc(c2O)O)C12CC3CC(C2)CC(C1)C3 | 10.6019/CHEMBL5442687 | ||
| 9637 | 208 | None | 8 | Human | Functional | pIC50 | = | 5.8 | 5.8 | -478 | 18 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 329 | 2 | 3 | 4 | 3.3 | NC[C@@H]1O[C@@H](Cc2c1ccc(c2O)O)C12CC3CC(C2)CC(C1)C3 | 10.6019/CHEMBL5442687 | ||
| CHEMBL291143 | 208 | None | 8 | Human | Functional | pIC50 | = | 5.8 | 5.8 | -478 | 18 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 329 | 2 | 3 | 4 | 3.3 | NC[C@@H]1O[C@@H](Cc2c1ccc(c2O)O)C12CC3CC(C2)CC(C1)C3 | 10.6019/CHEMBL5442687 | ||
| 135413536 | 448 | None | 58 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -7943 | 7 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 534 | 6 | 2 | 5 | 5.0 | Fc1ccc(cc1)[C@H]1[C@H](OCCN1Cc1[nH][nH]c(=O)n1)O[C@@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C | 10.6019/CHEMBL5442687 | ||
| 230 | 448 | None | 58 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -7943 | 7 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 534 | 6 | 2 | 5 | 5.0 | Fc1ccc(cc1)[C@H]1[C@H](OCCN1Cc1[nH][nH]c(=O)n1)O[C@@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C | 10.6019/CHEMBL5442687 | ||
| 3490 | 448 | None | 58 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -7943 | 7 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 534 | 6 | 2 | 5 | 5.0 | Fc1ccc(cc1)[C@H]1[C@H](OCCN1Cc1[nH][nH]c(=O)n1)O[C@@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C | 10.6019/CHEMBL5442687 | ||
| 6918365 | 448 | None | 58 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -7943 | 7 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 534 | 6 | 2 | 5 | 5.0 | Fc1ccc(cc1)[C@H]1[C@H](OCCN1Cc1[nH][nH]c(=O)n1)O[C@@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C | 10.6019/CHEMBL5442687 | ||
| CHEMBL1471 | 448 | None | 58 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -7943 | 7 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 534 | 6 | 2 | 5 | 5.0 | Fc1ccc(cc1)[C@H]1[C@H](OCCN1Cc1[nH][nH]c(=O)n1)O[C@@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C | 10.6019/CHEMBL5442687 | ||
| DB00673 | 448 | None | 58 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -7943 | 7 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 534 | 6 | 2 | 5 | 5.0 | Fc1ccc(cc1)[C@H]1[C@H](OCCN1Cc1[nH][nH]c(=O)n1)O[C@@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C | 10.6019/CHEMBL5442687 | ||
| 158797 | 3771 | None | 19 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -12 | 2 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 303 | 7 | 1 | 2 | 4.6 | COc1cccc(c1)[C@H](NCCCc1ccccc1Cl)C | 10.6019/CHEMBL5442687 | ||
| 718 | 3771 | None | 19 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -12 | 2 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 303 | 7 | 1 | 2 | 4.6 | COc1cccc(c1)[C@H](NCCCc1ccccc1Cl)C | 10.6019/CHEMBL5442687 | ||
| CHEMBL292376 | 3771 | None | 19 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -12 | 2 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 303 | 7 | 1 | 2 | 4.6 | COc1cccc(c1)[C@H](NCCCc1ccccc1Cl)C | 10.6019/CHEMBL5442687 | ||
| 621 | 3035 | None | 27 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -6309 | 6 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 554 | 9 | 4 | 5 | 5.6 | O=C(N[C@](C(=O)NCC1(CCCCC1)c1ccccn1)(Cc1c[nH]c2c1cccc2)C)Nc1ccc(cc1)[N+](=O)[O-] | 10.6019/CHEMBL5442687 | ||
| 9937534 | 3035 | None | 27 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -6309 | 6 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 554 | 9 | 4 | 5 | 5.6 | O=C(N[C@](C(=O)NCC1(CCCCC1)c1ccccn1)(Cc1c[nH]c2c1cccc2)C)Nc1ccc(cc1)[N+](=O)[O-] | 10.6019/CHEMBL5442687 | ||
| CHEMBL329650 | 3035 | None | 27 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -6309 | 6 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 554 | 9 | 4 | 5 | 5.6 | O=C(N[C@](C(=O)NCC1(CCCCC1)c1ccccn1)(Cc1c[nH]c2c1cccc2)C)Nc1ccc(cc1)[N+](=O)[O-] | 10.6019/CHEMBL5442687 | ||
| 4534 | 192011 | None | 61 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -27 | 5 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 302 | 5 | 4 | 4 | 3.6 | CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 | 10.6019/CHEMBL5442687 | ||
| CHEMBL52 | 192011 | None | 61 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -27 | 5 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 302 | 5 | 4 | 4 | 3.6 | CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 | 10.6019/CHEMBL5442687 | ||
| 512282 | 758 | None | 42 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -354 | 5 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 434 | 6 | 2 | 4 | 3.1 | NC(=O)Nc1cc(Cl)ccc1OCC(=O)N1CCN(C[C@H]1C)Cc1ccc(cc1)F | 10.6019/CHEMBL5442687 | ||
| 767 | 758 | None | 42 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -354 | 5 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 434 | 6 | 2 | 4 | 3.1 | NC(=O)Nc1cc(Cl)ccc1OCC(=O)N1CCN(C[C@H]1C)Cc1ccc(cc1)F | 10.6019/CHEMBL5442687 | ||
| CHEMBL232656 | 758 | None | 42 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -354 | 5 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 434 | 6 | 2 | 4 | 3.1 | NC(=O)Nc1cc(Cl)ccc1OCC(=O)N1CCN(C[C@H]1C)Cc1ccc(cc1)F | 10.6019/CHEMBL5442687 | ||
| 9893924 | 4750 | None | 24 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -89 | 9 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 554 | 11 | 3 | 4 | 5.4 | S=C(NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 | 10.6019/CHEMBL5442687 | ||
| CHEMBL103769 | 4750 | None | 24 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -89 | 9 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 554 | 11 | 3 | 4 | 5.4 | S=C(NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 | 10.6019/CHEMBL5442687 | ||
| 2202 | 2761 | None | 30 | Human | Functional | pIC50 | = | 5.6 | 5.6 | - | 1 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 629 | 8 | 1 | 9 | 2.9 | COc1cc(OC)ccc1S(=O)(=O)N1c2ccc(cc2[C@@](C1=O)(N1C[C@@H](C[C@H]1C(=O)N(C)C)O)c1ccccc1OC)Cl | 10.6019/CHEMBL5442687 | ||
| 9895468 | 2761 | None | 30 | Human | Functional | pIC50 | = | 5.6 | 5.6 | - | 1 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 629 | 8 | 1 | 9 | 2.9 | COc1cc(OC)ccc1S(=O)(=O)N1c2ccc(cc2[C@@](C1=O)(N1C[C@@H](C[C@H]1C(=O)N(C)C)O)c1ccccc1OC)Cl | 10.6019/CHEMBL5442687 | ||
| CHEMBL582857 | 2761 | None | 30 | Human | Functional | pIC50 | = | 5.6 | 5.6 | - | 1 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 629 | 8 | 1 | 9 | 2.9 | COc1cc(OC)ccc1S(=O)(=O)N1c2ccc(cc2[C@@](C1=O)(N1C[C@@H](C[C@H]1C(=O)N(C)C)O)c1ccccc1OC)Cl | 10.6019/CHEMBL5442687 | ||
| DB12643 | 2761 | None | 30 | Human | Functional | pIC50 | = | 5.6 | 5.6 | - | 1 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 629 | 8 | 1 | 9 | 2.9 | COc1cc(OC)ccc1S(=O)(=O)N1c2ccc(cc2[C@@](C1=O)(N1C[C@@H](C[C@H]1C(=O)N(C)C)O)c1ccccc1OC)Cl | 10.6019/CHEMBL5442687 | ||
| 2419 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -4365 | 19 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | ||
| 5152 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -4365 | 19 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | ||
| 5152.0 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -4365 | 19 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | ||
| 559 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -4365 | 19 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | ||
| CHEMBL1263 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -4365 | 19 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | ||
| DB00938 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -4365 | 19 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | ||
| 1209 | 1658 | None | 52 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -21 | 25 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 309 | 6 | 1 | 2 | 4.4 | CNCCC(c1ccccc1)Oc1ccc(cc1)C(F)(F)F | 10.6019/CHEMBL5442687 | ||
| 203 | 1658 | None | 52 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -21 | 25 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 309 | 6 | 1 | 2 | 4.4 | CNCCC(c1ccccc1)Oc1ccc(cc1)C(F)(F)F | 10.6019/CHEMBL5442687 | ||
| 3386 | 1658 | None | 52 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -21 | 25 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 309 | 6 | 1 | 2 | 4.4 | CNCCC(c1ccccc1)Oc1ccc(cc1)C(F)(F)F | 10.6019/CHEMBL5442687 | ||
| CHEMBL41 | 1658 | None | 52 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -21 | 25 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 309 | 6 | 1 | 2 | 4.4 | CNCCC(c1ccccc1)Oc1ccc(cc1)C(F)(F)F | 10.6019/CHEMBL5442687 | ||
| DB00472 | 1658 | None | 52 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -21 | 25 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 309 | 6 | 1 | 2 | 4.4 | CNCCC(c1ccccc1)Oc1ccc(cc1)C(F)(F)F | 10.6019/CHEMBL5442687 | ||
| 9893924 | 4750 | None | 24 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -89 | 9 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 554 | 11 | 3 | 4 | 5.4 | S=C(NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 | 10.6019/CHEMBL5442687 | ||
| CHEMBL103769 | 4750 | None | 24 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -89 | 9 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 554 | 11 | 3 | 4 | 5.4 | S=C(NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 | 10.6019/CHEMBL5442687 | ||
| 52936725 | 61270 | None | 22 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -602 | 10 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 432 | 6 | 2 | 4 | 6.3 | Cc1cc(C)cc(-c2cnc3cc(Cl)c(-c4cccc(O)c4)cc3c2OCCCN)c1 | 10.6019/CHEMBL5442687 | ||
| CHEMBL1766103 | 61270 | None | 22 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -602 | 10 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 432 | 6 | 2 | 4 | 6.3 | Cc1cc(C)cc(-c2cnc3cc(Cl)c(-c4cccc(O)c4)cc3c2OCCCN)c1 | 10.6019/CHEMBL5442687 | ||
| 10150497 | 4074 | None | 40 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -457 | 15 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 380 | 4 | 1 | 7 | 2.7 | NCCc1cn(c2c1cccc2)S(=O)(=O)c1c(Cl)nc2n1ccs2 | 10.6019/CHEMBL5442687 | ||
| 3240 | 4074 | None | 40 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -457 | 15 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 380 | 4 | 1 | 7 | 2.7 | NCCc1cn(c2c1cccc2)S(=O)(=O)c1c(Cl)nc2n1ccs2 | 10.6019/CHEMBL5442687 | ||
| CHEMBL392760 | 4074 | None | 40 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -457 | 15 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 380 | 4 | 1 | 7 | 2.7 | NCCc1cn(c2c1cccc2)S(=O)(=O)c1c(Cl)nc2n1ccs2 | 10.6019/CHEMBL5442687 | ||
| 156419 | 938 | None | 48 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -70 | 20 | GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65GPCR PRESTO-Tango dose-response in antagonist mode with target: GPR65 |
ChEMBL | 357 | 6 | 1 | 1 | 6.1 | C[C@H](c1cccc2c1cccc2)NCCCc1cccc(c1)C(F)(F)F | 10.6019/CHEMBL5442687 | ||
Showing 1 to 50 of 161 entries
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| No data available in table | ||||||||||||||||||||||
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