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Ligand source activities (1 row/activity)

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

CHEMBL1742484	60306	None	2	Human	Binding	EC50	=	520.00	6.28	-	6	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	523.3	24	4	8	4.47	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL1742484	60306	None	2	Human	Binding	EC50	=	524.81	6.28	-	6	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	523.3	24	4	8	4.47	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL1958251	71419	None	6	Human	Binding	EC50	=	5600.00	5.25	-	1	Allosteric modulator activity at human GPR174 by CRA	ChEMBL	275.0	3	2	4	2.20	O=C(N/N=C/c1cc(Cl)ccc1O)c1ccncc1	-
CHEMBL3577138	121215	None	0	Human	Binding	EC50	=	1900.00	5.72	-	3	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	523.3	24	4	8	4.47	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577138	121215	None	0	Human	Binding	EC50	=	1905.46	5.72	-	3	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	523.3	24	4	8	4.47	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577141	121217	None	0	Human	Binding	EC50	=	2000.00	5.70	-	2	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	525.3	24	3	7	5.45	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](F)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577141	121217	None	0	Human	Binding	EC50	=	1995.26	5.70	-	2	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	525.3	24	3	7	5.45	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](F)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577144	121219	None	0	Human	Binding	EC50	=	290.00	6.54	-	3	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	495.3	22	4	8	3.69	CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577144	121219	None	0	Human	Binding	EC50	=	288.40	6.54	-	3	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	495.3	22	4	8	3.69	CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577145	121220	None	2	Human	Binding	EC50	=	540.00	6.27	-	3	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	497.3	23	4	8	3.92	CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577145	121220	None	2	Human	Binding	EC50	=	537.03	6.27	-	3	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	497.3	23	4	8	3.92	CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577146	121221	None	0	Human	Binding	EC50	=	770.00	6.11	-	2	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	469.2	21	4	8	3.14	CCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577146	121221	None	0	Human	Binding	EC50	=	776.25	6.11	-	2	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	469.2	21	4	8	3.14	CCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577147	121222	None	0	Human	Binding	EC50	=	1800.00	5.75	-	3	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	441.2	19	4	8	2.36	CCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577147	121222	None	0	Human	Binding	EC50	=	1778.28	5.75	-	3	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	441.2	19	4	8	2.36	CCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577156	121230	None	0	Human	Binding	EC50	=	63.00	7.20	-	2	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	522.3	24	5	7	4.05	CCCCCCCC/C=C\CCCCCCCC(=O)NC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577156	121230	None	0	Human	Binding	EC50	=	63.10	7.20	-	2	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	522.3	24	5	7	4.05	CCCCCCCC/C=C\CCCCCCCC(=O)NC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577158	121232	None	0	Human	Binding	EC50	=	1100.00	5.96	-	2	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	537.3	24	3	9	4.56	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)OC	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577158	121232	None	0	Human	Binding	EC50	=	1096.48	5.96	-	2	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	537.3	24	3	9	4.56	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OC[C@H](N)C(=O)OC	https://dx.doi.org/10.1021/jm5020082
CHEMBL3577162	121234	None	0	Human	Binding	EC50	=	830.00	6.08	-	1	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	ChEMBL	537.3	24	4	8	4.86	CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O[C@@H](C)[C@H](N)C(=O)O	https://dx.doi.org/10.1021/jm5020082

Showing 1 to 20 of 58 entries

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

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Ligand source activities (1 row/activity)