Ligand source activities (1 row/activity)
| Ligands | Receptor | Assay information | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name |
GPCRdb ID | #Vendors | Reference ligand |
Fold selectivity (Potency) |
# tested GPCRs (Potency) |
Species | p-value (-log) |
Type | Activity Relation |
Activity Value |
Assay Type | Assay Description | Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI |
| 1079 | 7688 | 44 | None | 63 | 4 | Rat | 6.7 | pEC50 | None | 6.7 | Functional | Guide to Pharmacology | 292 | 3 | 2 | 2 | 4.5 | OCC(Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(C)C | 11641424 | ||
| 1079 | 7688 | 44 | None | 63 | 4 | Rat | 6.7 | pEC50 | None | 6.7 | Functional | Guide to Pharmacology | 292 | 3 | 2 | 2 | 4.5 | OCC(Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(C)C | 15126507 | ||
| 5024764 | 7688 | 44 | None | 63 | 4 | Rat | 6.7 | pEC50 | None | 6.7 | Functional | Guide to Pharmacology | 292 | 3 | 2 | 2 | 4.5 | OCC(Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(C)C | 11641424 | ||
| 5024764 | 7688 | 44 | None | 63 | 4 | Rat | 6.7 | pEC50 | None | 6.7 | Functional | Guide to Pharmacology | 292 | 3 | 2 | 2 | 4.5 | OCC(Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(C)C | 15126507 | ||
| CHEMBL1256697 | 7688 | 44 | None | 63 | 4 | Rat | 6.7 | pEC50 | None | 6.7 | Functional | Guide to Pharmacology | 292 | 3 | 2 | 2 | 4.5 | OCC(Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(C)C | 11641424 | ||
| CHEMBL1256697 | 7688 | 44 | None | 63 | 4 | Rat | 6.7 | pEC50 | None | 6.7 | Functional | Guide to Pharmacology | 292 | 3 | 2 | 2 | 4.5 | OCC(Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(C)C | 15126507 | ||
| 2997 | 199930 | 35 | None | -13 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | 270 | 1 | 1 | 2 | 3.1 | O=C1CN=C(c2ccccc2)c2cc(Cl)ccc2N1 | None | ||
| CHEMBL523 | 199930 | 35 | None | -13 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | 270 | 1 | 1 | 2 | 3.1 | O=C1CN=C(c2ccccc2)c2cc(Cl)ccc2N1 | None | ||
| Ligands | Receptor | Assay information | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name |
GPCRdb ID | #Vendors | Reference ligand |
Fold selectivity (Affinity) |
# tested GPCRs (Affinity) |
Species | p-value (-log) |
Type | Activity Relation |
Activity Value |
Assay Type | Assay Description | Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI |