Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 1499 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 3779 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 3779.0 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 536 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| CHEMBL434 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| DB01064 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.3 | 8.3 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
| 1499 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 3779 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 3779.0 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 536 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| CHEMBL434 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| DB01064 | 2091 | None | 34 | Human | Functional | pEC50 | = | 8.1 | 8.1 | -63 | 38 | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
| 2367 | 964 | None | 47 | Human | Functional | pEC50 | = | 3.0 | 3.0 | -1148 | 6 | UnclassifiedUnclassified |
Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
| 6167 | 964 | None | 47 | Human | Functional | pEC50 | = | 3.0 | 3.0 | -1148 | 6 | UnclassifiedUnclassified |
Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
| 726 | 964 | None | 47 | Human | Functional | pEC50 | = | 3.0 | 3.0 | -1148 | 6 | UnclassifiedUnclassified |
Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
| CHEMBL107 | 964 | None | 47 | Human | Functional | pEC50 | = | 3.0 | 3.0 | -1148 | 6 | UnclassifiedUnclassified |
Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
| DB01394 | 964 | None | 47 | Human | Functional | pEC50 | = | 3.0 | 3.0 | -1148 | 6 | UnclassifiedUnclassified |
Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
| 12423 | 3692 | None | 0 | Human | Functional | pEC50 | = | 3.5 | 3.5 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 804 | 9 | 11 | 18 | -2.9 | C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@](C3)(C(=C)C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)(C)C(=O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O | 22616809 | ||
| 442089 | 3692 | None | 0 | Human | Functional | pEC50 | = | 3.5 | 3.5 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 804 | 9 | 11 | 18 | -2.9 | C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@](C3)(C(=C)C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)(C)C(=O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O | 22616809 | ||
| CHEMBL444122 | 3692 | None | 0 | Human | Functional | pEC50 | = | 3.5 | 3.5 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 804 | 9 | 11 | 18 | -2.9 | C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@](C3)(C(=C)C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)(C)C(=O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O | 22616809 | ||
| 138107041 | 561 | None | 43 | Human | Functional | pEC50 | = | 4.1 | 4.1 | -562 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
| 276 | 561 | None | 43 | Human | Functional | pEC50 | = | 4.1 | 4.1 | -562 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
| 447043 | 561 | None | 43 | Human | Functional | pEC50 | = | 4.1 | 4.1 | -562 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
| 6510 | 561 | None | 43 | Human | Functional | pEC50 | = | 4.1 | 4.1 | -562 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
| CHEMBL529 | 561 | None | 43 | Human | Functional | pEC50 | = | 4.1 | 4.1 | -562 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
| DB00207 | 561 | None | 43 | Human | Functional | pEC50 | = | 4.1 | 4.1 | -562 | 3 | UnclassifiedUnclassified |
Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
| 12424 | 2372 | None | 0 | Human | Functional | pEC50 | = | 4.5 | 4.5 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 23214402 | ||||
| 44398561 | 2372 | None | 0 | Human | Functional | pEC50 | = | 4.5 | 4.5 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 23214402 | ||||
| CHEMBL434535 | 2372 | None | 0 | Human | Functional | pEC50 | = | 4.5 | 4.5 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 23214402 | ||||
| 10362 | 227 | None | 44 | Human | Functional | pIC50 | = | 4.5 | 4.5 | -1096 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 264 | 3 | 2 | 3 | 2.3 | OC(=O)/C=C(\C=C\C1(O)C(=CC(=O)CC1(C)C)C)/C | 25844797 | ||
| 5375199 | 227 | None | 44 | Human | Functional | pIC50 | = | 4.5 | 4.5 | -1096 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 264 | 3 | 2 | 3 | 2.3 | OC(=O)/C=C(\C=C\C1(O)C(=CC(=O)CC1(C)C)C)/C | 25844797 | ||
| CHEMBL379808 | 227 | None | 44 | Human | Functional | pIC50 | = | 4.5 | 4.5 | -1096 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | 264 | 3 | 2 | 3 | 2.3 | OC(=O)/C=C(\C=C\C1(O)C(=CC(=O)CC1(C)C)C)/C | 25844797 | ||
Showing 1 to 32 of 32 entries
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| No data available in table | ||||||||||||||||||||||
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