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Ligand source activities (1 row/activity)

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Ligands (move mouse cursor over ligand name to see structure)					Receptor		Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found		Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found

Ligands (move mouse cursor over ligand name to see structure)					Receptor	Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found	Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found
	23259348	170016	None	0	Human	Functional	pEC50	=	4.7	4.7	-1	3	Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 100 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 100 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1	nan
	CHEMBL4440983	170016	None	0	Human	Functional	pEC50	=	4.7	4.7	-1	3	Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 100 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 100 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1	nan
	68344426	175800	None	0	Human	Functional	pEC50	=	4.6	4.6	-3	3	Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level by FLIPR assayAgonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level by FLIPR assay	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)C2CC1	nan
	CHEMBL4582048	175800	None	0	Human	Functional	pEC50	=	4.6	4.6	-3	3	Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level by FLIPR assayAgonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level by FLIPR assay	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)C2CC1	nan
	23259348	170016	None	0	Human	Functional	pEC50	=	4.6	4.6	-1	3	Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by FLIPR assayAgonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by FLIPR assay	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1	nan
	CHEMBL4440983	170016	None	0	Human	Functional	pEC50	=	4.6	4.6	-1	3	Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by FLIPR assayAgonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by FLIPR assay	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1	nan
	23259348	170016	None	0	Human	Functional	pEC50	=	5.6	5.6	-1	3	Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 10 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 10 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1	nan
	CHEMBL4440983	170016	None	0	Human	Functional	pEC50	=	5.6	5.6	-1	3	Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 10 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 10 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1	nan
	1499	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
	3779	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
	3779.0	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
	536	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
	CHEMBL434	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
	DB01064	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
	2360	3693	None	28	Human	Functional	pEC50	=	4.4	4.4	-19	2	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	2484	3693	None	28	Human	Functional	pEC50	=	4.4	4.4	-19	2	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	347	3693	None	28	Human	Functional	pEC50	=	4.4	4.4	-19	2	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	441071	3693	None	28	Human	Functional	pEC50	=	4.4	4.4	-19	2	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	CHEMBL227934	3693	None	28	Human	Functional	pEC50	=	4.4	4.4	-19	2	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	DB15954	3693	None	28	Human	Functional	pEC50	=	4.4	4.4	-19	2	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	2360	3693	None	28	Human	Functional	pEC50	=	5.3	5.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	2484	3693	None	28	Human	Functional	pEC50	=	5.3	5.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	347	3693	None	28	Human	Functional	pEC50	=	5.3	5.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	441071	3693	None	28	Human	Functional	pEC50	=	5.3	5.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	CHEMBL227934	3693	None	28	Human	Functional	pEC50	=	5.3	5.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	DB15954	3693	None	28	Human	Functional	pEC50	=	5.3	5.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	nan
	23259348	170016	None	0	Human	Functional	pEC50	=	5.3	5.3	-1	3	Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 30 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 30 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1	nan
	CHEMBL4440983	170016	None	0	Human	Functional	pEC50	=	5.3	5.3	-1	3	Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 30 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)Competitive-antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R10 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of strychnine-induced increase in intracellular calcium level by measuring strychnine EC50 at 30 uM by FLIPR assay (Rvb = 0.39 +/- 0.09 uM)	ChEMBL	250	0	1	3	2.6	C/C1=C\C[C@H](O)/C(C)=C/[C@H]2OC(=O)[C@@H](C)[C@@H]2CC1	nan
	342	732	None	34	Human	Functional	pEC50	=	4.2	4.2	-	1	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	394	2	0	5	2.1	COc1cc2c(cc1OC)N1[C@@H]3[C@@]42CCN2[C@H]4C[C@@H]4[C@H]3[C@H](CC1=O)OCC=C4C2	nan
	442021	732	None	34	Human	Functional	pEC50	=	4.2	4.2	-	1	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	394	2	0	5	2.1	COc1cc2c(cc1OC)N1[C@@H]3[C@@]42CCN2[C@H]4C[C@@H]4[C@H]3[C@H](CC1=O)OCC=C4C2	nan
	CHEMBL501756	732	None	34	Human	Functional	pEC50	=	4.2	4.2	-	1	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	394	2	0	5	2.1	COc1cc2c(cc1OC)N1[C@@H]3[C@@]42CCN2[C@H]4C[C@@H]4[C@H]3[C@H](CC1=O)OCC=C4C2	nan
	12433	1365	None	6	Human	Functional	pEC50	=	4.2	4.2	-269	4	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	325	7	1	1	4.3	CC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C	nan
	15488	1365	None	6	Human	Functional	pEC50	=	4.2	4.2	-269	4	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	325	7	1	1	4.3	CC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C	nan
	CHEMBL1738972	1365	None	6	Human	Functional	pEC50	=	4.2	4.2	-269	4	Activity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay	ChEMBL	325	7	1	1	4.3	CC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C	nan
	2360	3693	None	28	Human	Functional	pEC50	=	8.3	8.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	Drug Central	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	None
	2484	3693	None	28	Human	Functional	pEC50	=	8.3	8.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	Drug Central	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	None
	347	3693	None	28	Human	Functional	pEC50	=	8.3	8.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	Drug Central	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	None
	441071	3693	None	28	Human	Functional	pEC50	=	8.3	8.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	Drug Central	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	None
	CHEMBL227934	3693	None	28	Human	Functional	pEC50	=	8.3	8.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	Drug Central	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	None
	DB15954	3693	None	28	Human	Functional	pEC50	=	8.3	8.3	-19	2	Activity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assayActivity at human TAS2R10 expressed in HEK293/15 cells assessed as effect on calcium response by FLIPR assay	Drug Central	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	None
	1499	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
	3779	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
	3779.0	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
	536	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
	CHEMBL434	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
	DB01064	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R10 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
	12433	1365	None	6	Human	Functional	pEC50	=	4.1	4.1	-269	4	UnclassifiedUnclassified	Guide to Pharmacology	325	7	1	1	4.3	CC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C	23283334
	15488	1365	None	6	Human	Functional	pEC50	=	4.1	4.1	-269	4	UnclassifiedUnclassified	Guide to Pharmacology	325	7	1	1	4.3	CC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C	23283334
	CHEMBL1738972	1365	None	6	Human	Functional	pEC50	=	4.1	4.1	-269	4	UnclassifiedUnclassified	Guide to Pharmacology	325	7	1	1	4.3	CC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C	23283334
	2360	3693	None	28	Human	Functional	pEC50	=	4.5	4.5	-19	2	UnclassifiedUnclassified	Guide to Pharmacology	334	0	0	3	2.1	O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3	20022913

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Ligands (move mouse cursor over ligand name to see structure)					Receptor		Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found		Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found

Ligands (move mouse cursor over ligand name to see structure)					Receptor		Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found		Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found
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Ligand source activities (1 row/activity)