GPCRdb

Refined structure (6OMM) of G_i1 - FPR2/ALX

Full

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

G_i/o

DATE

2024-02-01

3D VIEW

NGL is a WebGL based 3D viewer powered by MMTF.

Structure

GPCR

Gα

Gβ

Gγ
Model

AlphaFold2-Multimer

REFINED G PROTEIN RESIDUES

Residue backbones - 217 from structure (61.3%), 137 from model (38.7%)
Residue sidechains - 214 from structure (60.5%), 140 from model (39.5%)

Showing 1 to 354 of 354 entries

Search:

Segment	Seq.num.	AA	CGN#	Backbone from	Sidechain from
	:

Segment	Seq.num.	AA	CGN#	Backbone from	Sidechain from

G.HN	1	M	G.HN.01	AF2	AF2
G.HN	2	G	G.HN.02	AF2	AF2
G.HN	3	C	G.HN.09	AF2	AF2
G.HN	4	T	G.HN.10	AF2	AF2
G.HN	5	L	G.HN.11	Structure	Structure
G.HN	6	S	G.HN.30	Structure	Structure
G.HN	7	A	G.HN.31	Structure	Structure
G.HN	8	E	G.HN.32	Structure	Structure
G.HN	9	D	G.HN.33	Structure	Structure
G.HN	10	K	G.HN.34	Structure	Structure
G.HN	11	A	G.HN.35	Structure	Structure
G.HN	12	A	G.HN.36	Structure	Structure
G.HN	13	V	G.HN.37	Structure	Structure
G.HN	14	E	G.HN.38	Structure	Structure
G.HN	15	R	G.HN.39	Structure	Structure
G.HN	16	S	G.HN.40	Structure	Structure
G.HN	17	K	G.HN.41	Structure	Structure
G.HN	18	M	G.HN.42	Structure	Structure
G.HN	19	I	G.HN.43	Structure	Structure
G.HN	20	D	G.HN.44	Structure	Structure
G.HN	21	R	G.HN.45	Structure	Structure
G.HN	22	N	G.HN.46	Structure	Structure
G.HN	23	L	G.HN.47	Structure	Structure
G.HN	24	R	G.HN.48	Structure	Structure
G.HN	25	E	G.HN.49	Structure	Structure
G.HN	26	D	G.HN.50	Structure	Structure
G.HN	27	G	G.HN.51	Structure	Structure
G.HN	28	E	G.HN.52	Structure	Structure
G.HN	29	K	G.HN.53	Structure	Structure
G.hns1	30	A	G.hns1.01	Structure	Structure
G.hns1	31	A	G.hns1.02	Structure	Structure
G.hns1	32	R	G.hns1.03	Structure	Structure
G.S1	33	E	G.S1.01	Structure	Structure
G.S1	34	V	G.S1.02	Structure	Structure
G.S1	35	K	G.S1.03	Structure	Structure
G.S1	36	L	G.S1.04	Structure	Structure
G.S1	37	L	G.S1.05	Structure	Structure
G.S1	38	L	G.S1.06	Structure	Structure
G.S1	39	L	G.S1.07	Structure	Structure
G.s1h1	40	G	G.s1h1.01	Structure	Structure
G.s1h1	41	A	G.s1h1.02	Structure	Structure
G.s1h1	42	G	G.s1h1.03	Structure	Structure
G.s1h1	43	E	G.s1h1.04	Structure	Structure
G.s1h1	44	S	G.s1h1.05	Structure	Structure
G.s1h1	45	G	G.s1h1.06	Structure	Structure
G.H1	46	K	G.H1.01	Structure	Structure
G.H1	47	S	G.H1.02	Structure	Structure
G.H1	48	T	G.H1.03	Structure	Structure
G.H1	49	I	G.H1.04	Structure	Structure
G.H1	50	V	G.H1.05	Structure	Structure
G.H1	51	K	G.H1.06	Structure	Structure
G.H1	52	Q	G.H1.07	Structure	Structure
G.H1	53	M	G.H1.08	Structure	Structure
G.H1	54	K	G.H1.09	Structure	Structure
G.H1	55	I	G.H1.10	Structure	Structure
G.H1	56	I	G.H1.11	AF2	AF2
G.H1	57	H	G.H1.12	AF2	AF2
G.h1ha	58	E	G.h1ha.01	AF2	AF2
G.h1ha	59	A	G.h1ha.02	AF2	AF2
G.h1ha	60	G	G.h1ha.03	AF2	AF2
G.h1ha	61	Y	G.h1ha.04	AF2	AF2
G.h1ha	62	S	G.h1ha.05	AF2	AF2
H.HA	63	E	H.HA.01	AF2	AF2
H.HA	64	E	H.HA.02	AF2	AF2
H.HA	65	E	H.HA.03	AF2	AF2
H.HA	66	C	H.HA.04	AF2	AF2
H.HA	67	K	H.HA.05	AF2	AF2
H.HA	68	Q	H.HA.06	AF2	AF2
H.HA	69	Y	H.HA.07	AF2	AF2
H.HA	70	K	H.HA.08	AF2	AF2
H.HA	71	A	H.HA.09	AF2	AF2
H.HA	72	V	H.HA.10	AF2	AF2
H.HA	73	V	H.HA.11	AF2	AF2
H.HA	74	Y	H.HA.12	AF2	AF2
H.HA	75	S	H.HA.13	AF2	AF2
H.HA	76	N	H.HA.14	AF2	AF2
H.HA	77	T	H.HA.15	AF2	AF2
H.HA	78	I	H.HA.16	AF2	AF2
H.HA	79	Q	H.HA.17	AF2	AF2
H.HA	80	S	H.HA.18	AF2	AF2
H.HA	81	I	H.HA.19	AF2	AF2
H.HA	82	I	H.HA.20	AF2	AF2
H.HA	83	A	H.HA.21	AF2	AF2
H.HA	84	I	H.HA.22	AF2	AF2
H.HA	85	I	H.HA.23	AF2	AF2
H.HA	86	R	H.HA.24	AF2	AF2
H.HA	87	A	H.HA.25	AF2	AF2
H.HA	88	M	H.HA.26	AF2	AF2
H.HA	89	G	H.HA.27	AF2	AF2
H.HA	90	R	H.HA.28	AF2	AF2
H.HA	91	L	H.HA.29	AF2	AF2
H.hahb	92	K	H.hahb.01	AF2	AF2
H.hahb	93	I	H.hahb.04	AF2	AF2
H.hahb	94	D	H.hahb.05	AF2	AF2
H.hahb	95	F	H.hahb.06	AF2	AF2
H.hahb	96	G	H.hahb.07	AF2	AF2
H.hahb	97	D	H.hahb.08	AF2	AF2
H.hahb	98	S	H.hahb.09	AF2	AF2
H.HB	99	A	H.HB.01	AF2	AF2
H.HB	100	R	H.HB.02	AF2	AF2
H.HB	101	A	H.HB.03	AF2	AF2
H.HB	102	D	H.HB.04	AF2	AF2
H.HB	103	D	H.HB.05	AF2	AF2
H.HB	104	A	H.HB.06	AF2	AF2
H.HB	105	R	H.HB.07	AF2	AF2
H.HB	106	Q	H.HB.08	AF2	AF2
H.HB	107	L	H.HB.09	AF2	AF2
H.HB	108	F	H.HB.10	AF2	AF2
H.HB	109	V	H.HB.11	AF2	AF2
H.HB	110	L	H.HB.12	AF2	AF2
H.HB	111	A	H.HB.13	AF2	AF2
H.HB	112	G	H.HB.14	AF2	AF2
H.hbhc	113	A	H.hbhc.01	AF2	AF2
H.hbhc	114	A	H.hbhc.02	AF2	AF2
H.hbhc	115	E	H.hbhc.03	AF2	AF2
H.hbhc	116	E	H.hbhc.04	AF2	AF2
H.hbhc	117	G	H.hbhc.12	AF2	AF2
H.hbhc	118	F	H.hbhc.13	AF2	AF2
H.hbhc	119	M	H.hbhc.14	AF2	AF2
H.hbhc	120	T	H.hbhc.15	AF2	AF2
H.HC	121	A	H.HC.01	AF2	AF2
H.HC	122	E	H.HC.02	AF2	AF2
H.HC	123	L	H.HC.03	AF2	AF2
H.HC	124	A	H.HC.04	AF2	AF2
H.HC	125	G	H.HC.05	AF2	AF2
H.HC	126	V	H.HC.06	AF2	AF2
H.HC	127	I	H.HC.07	AF2	AF2
H.HC	128	K	H.HC.08	AF2	AF2
H.HC	129	R	H.HC.09	AF2	AF2
H.HC	130	L	H.HC.10	AF2	AF2
H.HC	131	W	H.HC.11	AF2	AF2
H.HC	132	K	H.HC.12	AF2	AF2
H.hchd	133	D	H.hchd.01	AF2	AF2
H.HD	134	S	H.HD.01	AF2	AF2
H.HD	135	G	H.HD.02	AF2	AF2
H.HD	136	V	H.HD.03	AF2	AF2
H.HD	137	Q	H.HD.04	AF2	AF2
H.HD	138	A	H.HD.05	AF2	AF2
H.HD	139	C	H.HD.06	AF2	AF2
H.HD	140	F	H.HD.07	AF2	AF2
H.HD	141	N	H.HD.08	AF2	AF2
H.HD	142	R	H.HD.09	AF2	AF2
H.HD	143	S	H.HD.10	AF2	AF2
H.HD	144	R	H.HD.11	AF2	AF2
H.HD	145	E	H.HD.12	AF2	AF2
H.hdhe	146	Y	H.hdhe.01	AF2	AF2
H.hdhe	147	Q	H.hdhe.02	AF2	AF2
H.hdhe	148	L	H.hdhe.03	AF2	AF2
H.hdhe	149	N	H.hdhe.04	AF2	AF2
H.hdhe	150	D	H.hdhe.05	AF2	AF2
H.HE	151	S	H.HE.01	AF2	AF2
H.HE	152	A	H.HE.02	AF2	AF2
H.HE	153	A	H.HE.03	AF2	AF2
H.HE	154	Y	H.HE.04	AF2	AF2
H.HE	155	Y	H.HE.05	AF2	AF2
H.HE	156	L	H.HE.06	AF2	AF2
H.HE	157	N	H.HE.07	AF2	AF2
H.HE	158	D	H.HE.08	AF2	AF2
H.HE	159	L	H.HE.09	AF2	AF2
H.HE	160	D	H.HE.10	AF2	AF2
H.HE	161	R	H.HE.11	AF2	AF2
H.HE	162	I	H.HE.12	AF2	AF2
H.HE	163	A	H.HE.13	AF2	AF2
H.hehf	164	Q	H.hehf.01	AF2	AF2
H.hehf	165	P	H.hehf.02	AF2	AF2
H.hehf	166	N	H.hehf.03	AF2	AF2
H.hehf	167	Y	H.hehf.04	AF2	AF2
H.hehf	168	I	H.hehf.05	AF2	AF2
H.hehf	169	P	H.hehf.06	AF2	AF2
H.hehf	170	T	H.hehf.07	AF2	AF2
H.HF	171	Q	H.HF.01	AF2	AF2
H.HF	172	Q	H.HF.02	AF2	AF2
H.HF	173	D	H.HF.03	AF2	AF2
H.HF	174	V	H.HF.04	AF2	AF2
H.HF	175	L	H.HF.05	AF2	AF2
H.HF	176	R	H.HF.06	AF2	AF2
G.hfs2	177	T	G.hfs2.01	AF2	AF2
G.hfs2	178	R	G.hfs2.02	AF2	AF2
G.hfs2	179	V	G.hfs2.03	AF2	AF2
G.hfs2	180	K	G.hfs2.04	AF2	AF2
G.hfs2	181	T	G.hfs2.05	AF2	AF2
G.hfs2	182	T	G.hfs2.06	Structure	Structure
G.hfs2	183	G	G.hfs2.07	Structure	Structure
G.S2	184	I	G.S2.01	Structure	Structure
G.S2	185	V	G.S2.02	Structure	Structure
G.S2	186	E	G.S2.03	Structure	Structure
G.S2	187	T	G.S2.04	Structure	Structure
G.S2	188	H	G.S2.05	Structure	Structure
G.S2	189	F	G.S2.06	Structure	Structure
G.S2	190	T	G.S2.07	Structure	Structure
G.S2	191	F	G.S2.08	Structure	Structure
G.s2s3	192	K	G.s2s3.01	Structure	Structure
G.s2s3	193	D	G.s2s3.02	Structure	Structure
G.S3	194	L	G.S3.01	Structure	Structure
G.S3	195	H	G.S3.02	Structure	Structure
G.S3	196	F	G.S3.03	Structure	Structure
G.S3	197	K	G.S3.04	Structure	Structure
G.S3	198	M	G.S3.05	Structure	Structure
G.S3	199	F	G.S3.06	Structure	Structure
G.S3	200	D	G.S3.07	Structure	Structure
G.S3	201	V	G.S3.08	Structure	Structure
G.s3h2	202	G	G.s3h2.01	Structure	Structure
G.s3h2	203	G	G.s3h2.02	Structure	AF2
G.s3h2	204	Q	G.s3h2.03	Structure	Structure
G.H2	205	R	G.H2.01	Structure	Structure
G.H2	206	S	G.H2.02	Structure	Structure
G.H2	207	E	G.H2.03	Structure	Structure
G.H2	208	R	G.H2.04	Structure	Structure
G.H2	209	K	G.H2.05	Structure	Structure
G.H2	210	K	G.H2.06	Structure	Structure
G.H2	211	W	G.H2.07	Structure	Structure
G.H2	212	I	G.H2.08	Structure	Structure
G.H2	213	H	G.H2.09	Structure	Structure
G.H2	214	C	G.H2.10	Structure	Structure
G.h2s4	215	F	G.h2s4.01	Structure	Structure
G.h2s4	216	E	G.h2s4.02	Structure	Structure
G.h2s4	217	G	G.h2s4.03	Structure	Structure
G.h2s4	218	V	G.h2s4.04	Structure	Structure
G.h2s4	219	T	G.h2s4.05	Structure	Structure
G.S4	220	A	G.S4.01	Structure	Structure
G.S4	221	I	G.S4.02	Structure	Structure
G.S4	222	I	G.S4.03	Structure	Structure
G.S4	223	F	G.S4.04	Structure	Structure
G.S4	224	C	G.S4.05	Structure	Structure
G.S4	225	V	G.S4.06	Structure	Structure
G.S4	226	A	G.S4.07	Structure	Structure
G.s4h3	227	L	G.s4h3.01	Structure	Structure
G.s4h3	228	S	G.s4h3.02	Structure	Structure
G.s4h3	229	D	G.s4h3.03	Structure	Structure
G.s4h3	230	Y	G.s4h3.04	Structure	Structure
G.s4h3	231	D	G.s4h3.05	Structure	Structure
G.s4h3	232	L	G.s4h3.06	Structure	Structure
G.s4h3	233	V	G.s4h3.07	Structure	Structure
G.s4h3	234	L	G.s4h3.08	AF2	AF2
G.s4h3	235	A	G.s4h3.09	AF2	AF2
G.s4h3	236	E	G.s4h3.10	AF2	AF2
G.s4h3	237	D	G.s4h3.11	AF2	AF2
G.s4h3	238	E	G.s4h3.12	AF2	AF2
G.s4h3	239	E	G.s4h3.13	AF2	AF2
G.s4h3	240	M	G.s4h3.14	AF2	AF2
G.s4h3	241	N	G.s4h3.15	Structure	Structure
G.H3	242	R	G.H3.01	Structure	Structure
G.H3	243	M	G.H3.02	Structure	Structure
G.H3	244	H	G.H3.03	Structure	Structure
G.H3	245	E	G.H3.04	Structure	Structure
G.H3	246	S	G.H3.05	Structure	Structure
G.H3	247	M	G.H3.06	Structure	Structure
G.H3	248	K	G.H3.07	Structure	Structure
G.H3	249	L	G.H3.08	Structure	Structure
G.H3	250	F	G.H3.09	Structure	Structure
G.H3	251	D	G.H3.10	Structure	Structure
G.H3	252	S	G.H3.11	Structure	Structure
G.H3	253	I	G.H3.12	Structure	Structure
G.H3	254	C	G.H3.13	Structure	Structure
G.H3	255	N	G.H3.14	Structure	Structure
G.H3	256	N	G.H3.15	Structure	Structure
G.H3	257	K	G.H3.16	Structure	Structure
G.H3	258	W	G.H3.17	Structure	Structure
G.H3	259	F	G.H3.18	Structure	Structure
G.h3s5	260	T	G.h3s5.01	Structure	Structure
G.h3s5	261	D	G.h3s5.02	Structure	Structure
G.h3s5	262	T	G.h3s5.03	Structure	Structure
G.S5	263	S	G.S5.01	Structure	Structure
G.S5	264	I	G.S5.02	Structure	Structure
G.S5	265	I	G.S5.03	Structure	Structure
G.S5	266	L	G.S5.04	Structure	Structure
G.S5	267	F	G.S5.05	Structure	Structure
G.S5	268	L	G.S5.06	Structure	Structure
G.S5	269	N	G.S5.07	Structure	Structure
G.s5hg	270	K	G.s5hg.01	Structure	Structure
G.HG	271	K	G.HG.01	Structure	Structure
G.HG	272	D	G.HG.02	Structure	Structure
G.HG	273	L	G.HG.03	Structure	Structure
G.HG	274	F	G.HG.04	Structure	Structure
G.HG	275	E	G.HG.05	Structure	Structure
G.HG	276	E	G.HG.06	Structure	Structure
G.HG	277	K	G.HG.07	Structure	Structure
G.HG	278	I	G.HG.08	Structure	Structure
G.HG	279	K	G.HG.09	Structure	Structure
G.HG	280	K	G.HG.12	Structure	Structure
G.HG	281	S	G.HG.13	Structure	Structure
G.HG	282	P	G.HG.14	Structure	Structure
G.HG	283	L	G.HG.15	Structure	Structure
G.HG	284	T	G.HG.16	Structure	Structure
G.HG	285	I	G.HG.17	Structure	Structure
G.hgh4	286	C	G.hgh4.01	Structure	Structure
G.hgh4	287	Y	G.hgh4.02	Structure	Structure
G.hgh4	288	P	G.hgh4.03	Structure	Structure
G.hgh4	289	E	G.hgh4.04	Structure	Structure
G.hgh4	290	Y	G.hgh4.05	Structure	Structure
G.hgh4	291	A	G.hgh4.06	Structure	Structure
G.hgh4	292	G	G.hgh4.07	Structure	Structure
G.hgh4	293	S	G.hgh4.08	Structure	Structure
G.H4	294	N	G.H4.01	Structure	Structure
G.H4	295	T	G.H4.02	Structure	Structure
G.H4	296	Y	G.H4.03	Structure	Structure
G.H4	297	E	G.H4.04	Structure	Structure
G.H4	298	E	G.H4.05	Structure	Structure
G.H4	299	A	G.H4.06	Structure	Structure
G.H4	300	A	G.H4.07	Structure	Structure
G.H4	301	A	G.H4.08	Structure	Structure
G.H4	302	Y	G.H4.10	Structure	Structure
G.H4	303	I	G.H4.11	Structure	Structure
G.H4	304	Q	G.H4.12	Structure	Structure
G.H4	305	C	G.H4.13	Structure	Structure
G.H4	306	Q	G.H4.14	Structure	Structure
G.H4	307	F	G.H4.15	Structure	Structure
G.H4	308	E	G.H4.16	Structure	Structure
G.H4	309	D	G.H4.17	Structure	Structure
G.h4s6	310	L	G.h4s6.01	Structure	Structure
G.h4s6	311	N	G.h4s6.02	Structure	Structure
G.h4s6	312	K	G.h4s6.03	Structure	Structure
G.h4s6	313	R	G.h4s6.04	Structure	Structure
G.h4s6	314	K	G.h4s6.08	Structure	Structure
G.h4s6	315	D	G.h4s6.09	Structure	Structure
G.h4s6	316	T	G.h4s6.10	Structure	Structure
G.h4s6	317	K	G.h4s6.11	Structure	Structure
G.h4s6	318	E	G.h4s6.12	Structure	Structure
G.S6	319	I	G.S6.01	Structure	Structure
G.S6	320	Y	G.S6.02	Structure	Structure
G.S6	321	T	G.S6.03	Structure	Structure
G.S6	322	H	G.S6.04	Structure	Structure
G.S6	323	F	G.S6.05	Structure	Structure
G.s6h5	324	T	G.s6h5.01	Structure	Structure
G.s6h5	325	C	G.s6h5.02	Structure	Structure
G.s6h5	326	A	G.s6h5.03	Structure	AF2
G.s6h5	327	T	G.s6h5.04	Structure	Structure
G.s6h5	328	D	G.s6h5.05	Structure	AF2
G.H5	329	T	G.H5.01	Structure	Structure
G.H5	330	K	G.H5.02	Structure	Structure
G.H5	331	N	G.H5.03	Structure	Structure
G.H5	332	V	G.H5.04	Structure	Structure
G.H5	333	Q	G.H5.05	Structure	Structure
G.H5	334	F	G.H5.06	Structure	Structure
G.H5	335	V	G.H5.07	Structure	Structure
G.H5	336	F	G.H5.08	Structure	Structure
G.H5	337	D	G.H5.09	Structure	Structure
G.H5	338	A	G.H5.10	Structure	Structure
G.H5	339	V	G.H5.11	Structure	Structure
G.H5	340	T	G.H5.12	Structure	Structure
G.H5	341	D	G.H5.13	Structure	Structure
G.H5	342	V	G.H5.14	Structure	Structure
G.H5	343	I	G.H5.15	Structure	Structure
G.H5	344	I	G.H5.16	Structure	Structure
G.H5	345	K	G.H5.17	Structure	Structure
G.H5	346	N	G.H5.18	Structure	Structure
G.H5	347	N	G.H5.19	Structure	Structure
G.H5	348	L	G.H5.20	Structure	Structure
G.H5	349	K	G.H5.21	Structure	Structure
G.H5	350	D	G.H5.22	Structure	Structure
G.H5	351	C	G.H5.23	Structure	Structure
G.H5	352	G	G.H5.24	Structure	Structure
G.H5	353	L	G.H5.25	Structure	Structure
G.H5	354	F	G.H5.26	Structure	Structure

REFINED GPCR RESIDUES

Residue backbones - 297 from structure (90.8%), 30 from model (9.2%)
Residue sidechains - 297 from structure (90.8%), 30 from model (9.2%)

Showing 1 to 327 of 327 entries

Search:

Segment	Seq.num.	AA	GPCRdb#	Backbone from	Sidechain from

N-term	1	M	-	AF2	AF2
N-term	2	E	-	AF2	AF2
N-term	3	T	-	AF2	AF2
N-term	4	N	-	AF2	AF2
N-term	5	F	-	AF2	AF2
N-term	6	S	-	AF2	AF2
N-term	7	T	-	AF2	AF2
N-term	8	P	-	AF2	AF2
N-term	9	L	-	AF2	AF2
N-term	10	N	-	AF2	AF2
N-term	11	E	-	AF2	AF2
N-term	12	Y	-	AF2	AF2
N-term	13	E	-	AF2	AF2
N-term	14	E	-	AF2	AF2
N-term	15	V	-	AF2	AF2
N-term	16	S	-	AF2	AF2
N-term	17	Y	-	AF2	AF2
N-term	18	E	-	AF2	AF2
TM1	19	S	1.25x25	AF2	AF2
TM1	20	A	1.26x26	AF2	AF2
TM1	21	G	1.27x27	Structure	Structure
TM1	22	Y	1.28x28	Structure	Structure
TM1	23	T	1.29x29	Structure	Structure
TM1	24	V	1.30x30	Structure	Structure
TM1	25	L	1.31x31	Structure	Structure
TM1	26	R	1.32x32	Structure	Structure
TM1	27	I	1.33x33	Structure	Structure
TM1	28	L	1.34x34	Structure	Structure
TM1	29	P	1.35x35	Structure	Structure
TM1	30	L	1.36x36	Structure	Structure
TM1	31	V	1.37x37	Structure	Structure
TM1	32	V	1.38x38	Structure	Structure
TM1	33	L	1.39x39	Structure	Structure
TM1	34	G	1.40x40	Structure	Structure
TM1	35	V	1.41x41	Structure	Structure
TM1	36	T	1.42x42	Structure	Structure
TM1	37	F	1.43x43	Structure	Structure
TM1	38	V	1.44x44	Structure	Structure
TM1	39	L	1.45x45	Structure	Structure
TM1	40	G	1.46x46	Structure	Structure
TM1	41	V	1.47x47	Structure	Structure
TM1	42	L	1.48x48	Structure	Structure
TM1	43	G	1.49x49	Structure	Structure
TM1	44	N	1.50x50	Structure	Structure
TM1	45	G	1.51x51	Structure	Structure
TM1	46	L	1.52x52	Structure	Structure
TM1	47	V	1.53x53	Structure	Structure
TM1	48	I	1.54x54	Structure	Structure
TM1	49	W	1.55x55	Structure	Structure
TM1	50	V	1.56x56	Structure	Structure
TM1	51	A	1.57x57	Structure	Structure
TM1	52	G	1.58x58	Structure	Structure
TM1	53	F	1.59x59	Structure	Structure
TM1	54	R	1.60x60	Structure	Structure
TM1	55	M	1.61x61	Structure	Structure
ICL1	56	T	-	Structure	Structure
ICL1	57	R	-	Structure	Structure
TM2	58	T	2.37x37	Structure	Structure
TM2	59	V	2.38x38	Structure	Structure
TM2	60	T	2.39x39	Structure	Structure
TM2	61	T	2.40x40	Structure	Structure
TM2	62	I	2.41x41	Structure	Structure
TM2	63	C	2.42x42	Structure	Structure
TM2	64	Y	2.43x43	Structure	Structure
TM2	65	L	2.44x44	Structure	Structure
TM2	66	N	2.45x45	Structure	Structure
TM2	67	L	2.46x46	Structure	Structure
TM2	68	A	2.47x47	Structure	Structure
TM2	69	L	2.48x48	Structure	Structure
TM2	70	A	2.49x49	Structure	Structure
TM2	71	D	2.50x50	Structure	Structure
TM2	72	F	2.51x51	Structure	Structure
TM2	73	S	2.52x52	Structure	Structure
TM2	74	F	2.53x53	Structure	Structure
TM2	75	T	2.54x54	Structure	Structure
TM2	76	A	2.55x55	Structure	Structure
TM2	77	T	2.56x56	Structure	Structure
TM2	78	L	2.57x57	Structure	Structure
TM2	79	P	2.58x58	Structure	Structure
TM2	80	F	2.59x59	Structure	Structure
TM2	81	L	2.60x60	Structure	Structure
TM2	82	I	2.61x61	Structure	Structure
TM2	83	V	2.62x62	Structure	Structure
TM2	84	S	2.63x63	Structure	Structure
TM2	85	M	2.64x64	Structure	Structure
TM2	86	A	2.65x65	Structure	Structure
TM2	87	M	2.66x66	Structure	Structure
TM2	88	G	2.67x67	Structure	Structure
ECL1	89	E	-	Structure	Structure
ECL1	90	K	23.49x49	Structure	Structure
ECL1	91	W	23.50x50	Structure	Structure
ECL1	92	P	23.51x51	Structure	Structure
ECL1	93	F	23.52x52	Structure	Structure
TM3	94	G	3.21x21	Structure	Structure
TM3	95	W	3.22x22	Structure	Structure
TM3	96	F	3.23x23	Structure	Structure
TM3	97	L	3.24x24	Structure	Structure
TM3	98	C	3.25x25	Structure	Structure
TM3	99	K	3.26x26	Structure	Structure
TM3	100	L	3.27x27	Structure	Structure
TM3	101	I	3.28x28	Structure	Structure
TM3	102	H	3.29x29	Structure	Structure
TM3	103	I	3.30x30	Structure	Structure
TM3	104	V	3.31x31	Structure	Structure
TM3	105	V	3.32x32	Structure	Structure
TM3	106	D	3.33x33	Structure	Structure
TM3	107	I	3.34x34	Structure	Structure
TM3	108	N	3.35x35	Structure	Structure
TM3	109	L	3.36x36	Structure	Structure
TM3	110	F	3.37x37	Structure	Structure
TM3	111	G	3.38x38	Structure	Structure
TM3	112	S	3.39x39	Structure	Structure
TM3	113	V	3.40x40	Structure	Structure
TM3	114	F	3.41x41	Structure	Structure
TM3	115	L	3.42x42	Structure	Structure
TM3	116	I	3.43x43	Structure	Structure
TM3	117	G	3.44x44	Structure	Structure
TM3	118	F	3.45x45	Structure	Structure
TM3	119	I	3.46x46	Structure	Structure
TM3	120	A	3.47x47	Structure	Structure
TM3	121	L	3.48x48	Structure	Structure
TM3	122	D	3.49x49	Structure	Structure
TM3	123	R	3.50x50	Structure	Structure
TM3	124	C	3.51x51	Structure	Structure
TM3	125	I	3.52x52	Structure	Structure
TM3	126	C	3.53x53	Structure	Structure
TM3	127	V	3.54x54	Structure	Structure
TM3	128	L	3.55x55	Structure	Structure
TM3	129	H	3.56x56	Structure	Structure
ICL2	130	P	34.50x50	Structure	Structure
ICL2	131	V	34.51x51	Structure	Structure
ICL2	132	W	34.52x52	Structure	Structure
ICL2	133	A	34.53x53	Structure	Structure
ICL2	134	Q	34.54x54	Structure	Structure
ICL2	135	N	34.55x55	Structure	Structure
ICL2	136	H	34.56x56	Structure	Structure
ICL2	137	R	34.57x57	Structure	Structure
TM4	138	T	4.38x38	Structure	Structure
TM4	139	V	4.39x39	Structure	Structure
TM4	140	S	4.40x40	Structure	Structure
TM4	141	L	4.41x41	Structure	Structure
TM4	142	A	4.42x42	Structure	Structure
TM4	143	M	4.43x43	Structure	Structure
TM4	144	K	4.44x44	Structure	Structure
TM4	145	V	4.45x45	Structure	Structure
TM4	146	I	4.46x46	Structure	Structure
TM4	147	V	4.47x47	Structure	Structure
TM4	148	G	4.48x48	Structure	Structure
TM4	149	P	4.49x49	Structure	Structure
TM4	150	W	4.50x50	Structure	Structure
TM4	151	I	4.51x51	Structure	Structure
TM4	152	L	4.52x52	Structure	Structure
TM4	153	A	4.53x53	Structure	Structure
TM4	154	L	4.54x54	Structure	Structure
TM4	155	V	4.55x55	Structure	Structure
TM4	156	L	4.56x56	Structure	Structure
TM4	157	T	4.57x57	Structure	Structure
TM4	158	L	4.58x59	Structure	Structure
TM4	159	P	4.59x60	Structure	Structure
TM4	160	V	4.60x61	Structure	Structure
TM4	161	F	4.61x62	Structure	Structure
TM4	162	L	4.62x63	Structure	Structure
TM4	163	F	4.63x64	Structure	Structure
TM4	164	L	4.64x65	Structure	Structure
ECL2	165	T	-	Structure	Structure
ECL2	166	T	-	Structure	Structure
ECL2	167	V	-	Structure	Structure
ECL2	168	T	-	Structure	Structure
ECL2	169	I	-	Structure	Structure
ECL2	170	P	-	Structure	Structure
ECL2	171	N	-	Structure	Structure
ECL2	172	G	-	Structure	Structure
ECL2	173	D	-	Structure	Structure
ECL2	174	T	-	Structure	Structure
ECL2	175	Y	-	Structure	Structure
ECL2	176	C	45.50x50	Structure	Structure
ECL2	177	T	45.51x51	Structure	Structure
ECL2	178	F	45.52x52	Structure	Structure
ECL2	179	N	-	Structure	Structure
ECL2	180	F	-	Structure	Structure
ECL2	181	A	-	Structure	Structure
ECL2	182	S	-	Structure	Structure
ECL2	183	W	-	Structure	Structure
ECL2	184	G	-	Structure	Structure
ECL2	185	G	-	Structure	Structure
TM5	186	T	5.23x24	Structure	Structure
TM5	187	P	5.24x25	Structure	Structure
TM5	188	E	5.25x26	Structure	Structure
TM5	189	E	5.26x27	Structure	Structure
TM5	190	R	5.27x28	Structure	Structure
TM5	191	L	5.28x29	Structure	Structure
TM5	192	K	5.29x30	Structure	Structure
TM5	193	V	5.30x31	Structure	Structure
TM5	194	A	5.31x32	Structure	Structure
TM5	195	I	5.32x33	Structure	Structure
TM5	196	T	5.33x34	Structure	Structure
TM5	197	M	5.34x35	Structure	Structure
TM5	198	L	5.35x36	Structure	Structure
TM5	199	T	5.36x37	Structure	Structure
TM5	200	A	5.37x38	Structure	Structure
TM5	201	R	5.38x39	Structure	Structure
TM5	202	G	5.39x40	Structure	Structure
TM5	203	I	5.40x41	Structure	Structure
TM5	204	I	5.41x42	Structure	Structure
TM5	205	R	5.42x43	Structure	Structure
TM5	206	F	5.43x44	Structure	Structure
TM5	207	V	5.44x45	Structure	Structure
TM5	208	I	5.45x46	Structure	Structure
TM5	209	G	5.46x461	Structure	Structure
TM5	210	F	5.47x47	Structure	Structure
TM5	211	S	5.48x48	Structure	Structure
TM5	212	L	5.49x49	Structure	Structure
TM5	213	P	5.50x50	Structure	Structure
TM5	214	M	5.51x51	Structure	Structure
TM5	215	S	5.52x52	Structure	Structure
TM5	216	I	5.53x53	Structure	Structure
TM5	217	V	5.54x54	Structure	Structure
TM5	218	A	5.55x55	Structure	Structure
TM5	219	I	5.56x56	Structure	Structure
TM5	220	C	5.57x57	Structure	Structure
TM5	221	Y	5.58x58	Structure	Structure
TM5	222	G	5.59x59	Structure	Structure
TM5	223	L	5.60x60	Structure	Structure
TM5	224	I	5.61x61	Structure	Structure
TM5	225	A	5.62x62	Structure	Structure
TM5	226	A	5.63x63	Structure	Structure
TM5	227	K	5.64x64	Structure	Structure
TM5	228	I	5.65x65	Structure	Structure
TM5	229	H	5.66x66	Structure	Structure
TM5	230	K	5.67x67	Structure	Structure
TM5	231	K	5.68x68	Structure	Structure
TM5	232	G	5.69x69	Structure	Structure
ICL3	233	M	-	Structure	Structure
ICL3	234	I	-	Structure	Structure
ICL3	235	K	-	Structure	Structure
ICL3	236	S	-	Structure	Structure
TM6	237	S	6.31x31	Structure	Structure
TM6	238	R	6.32x32	Structure	Structure
TM6	239	P	6.33x33	Structure	Structure
TM6	240	L	6.34x34	Structure	Structure
TM6	241	R	6.35x35	Structure	Structure
TM6	242	V	6.36x36	Structure	Structure
TM6	243	L	6.37x37	Structure	Structure
TM6	244	T	6.38x38	Structure	Structure
TM6	245	A	6.39x39	Structure	Structure
TM6	246	V	6.40x40	Structure	Structure
TM6	247	V	6.41x41	Structure	Structure
TM6	248	A	6.42x42	Structure	Structure
TM6	249	S	6.43x43	Structure	Structure
TM6	250	F	6.44x44	Structure	Structure
TM6	251	F	6.45x45	Structure	Structure
TM6	252	I	6.46x46	Structure	Structure
TM6	253	C	6.47x47	Structure	Structure
TM6	254	W	6.48x48	Structure	Structure
TM6	255	F	6.49x49	Structure	Structure
TM6	256	P	6.50x50	Structure	Structure
TM6	257	F	6.51x51	Structure	Structure
TM6	258	Q	6.52x52	Structure	Structure
TM6	259	L	6.53x53	Structure	Structure
TM6	260	V	6.54x54	Structure	Structure
TM6	261	A	6.55x55	Structure	Structure
TM6	262	L	6.56x56	Structure	Structure
TM6	263	L	6.57x57	Structure	Structure
TM6	264	G	6.58x58	Structure	Structure
TM6	265	T	6.59x59	Structure	Structure
TM6	266	V	6.60x60	Structure	Structure
TM6	267	W	6.61x61	Structure	Structure
ECL3	268	L	-	Structure	Structure
ECL3	269	K	-	Structure	Structure
ECL3	270	E	-	Structure	Structure
ECL3	271	M	-	Structure	Structure
ECL3	272	L	-	Structure	Structure
ECL3	273	F	-	Structure	Structure
ECL3	274	Y	-	Structure	Structure
ECL3	275	G	-	Structure	Structure
ECL3	276	K	-	Structure	Structure
TM7	277	Y	7.28x27	Structure	Structure
TM7	278	K	7.29x28	Structure	Structure
TM7	279	I	7.30x29	Structure	Structure
TM7	280	I	7.31x30	Structure	Structure
TM7	281	D	7.32x31	Structure	Structure
TM7	282	I	7.33x32	Structure	Structure
TM7	283	L	7.34x33	Structure	Structure
TM7	284	V	7.35x34	Structure	Structure
TM7	285	N	7.36x35	Structure	Structure
TM7	286	P	7.37x36	Structure	Structure
TM7	287	T	7.38x37	Structure	Structure
TM7	288	S	7.39x38	Structure	Structure
TM7	289	S	7.40x39	Structure	Structure
TM7	290	L	7.41x40	Structure	Structure
TM7	291	A	7.42x41	Structure	Structure
TM7	292	F	7.43x42	Structure	Structure
TM7	293	F	7.44x43	Structure	Structure
TM7	294	N	7.45x45	Structure	Structure
TM7	295	S	7.46x46	Structure	Structure
TM7	296	C	7.47x47	Structure	Structure
TM7	297	L	7.48x48	Structure	Structure
TM7	298	N	7.49x49	Structure	Structure
TM7	299	P	7.50x50	Structure	Structure
TM7	300	M	7.51x51	Structure	Structure
TM7	301	L	7.52x52	Structure	Structure
TM7	302	Y	7.53x53	Structure	Structure
TM7	303	V	7.54x54	Structure	Structure
TM7	304	F	7.55x55	Structure	Structure
TM7	305	V	7.56x56	Structure	Structure
H8	306	G	8.47x47	Structure	Structure
H8	307	Q	8.48x48	Structure	Structure
H8	308	D	8.49x49	Structure	Structure
H8	309	F	8.50x50	Structure	Structure
H8	310	R	8.51x51	Structure	Structure
H8	311	E	8.52x52	Structure	Structure
H8	312	R	8.53x53	Structure	Structure
H8	313	L	8.54x54	Structure	Structure
H8	314	I	8.55x55	Structure	Structure
H8	315	H	8.56x56	Structure	Structure
H8	316	S	8.57x57	Structure	Structure
H8	317	L	8.58x58	Structure	Structure
C-term	318	P	-	AF2	AF2
C-term	319	T	-	AF2	AF2
C-term	320	S	-	AF2	AF2
C-term	321	L	-	AF2	AF2
C-term	322	E	-	AF2	AF2
C-term	323	R	-	AF2	AF2
C-term	324	A	-	AF2	AF2
C-term	325	L	-	AF2	AF2
C-term	326	S	-	AF2	AF2
C-term	327	E	-	AF2	AF2

GPCR - G protein interface interactions

The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.

Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):

bb-bb

bb-sc

sc-sc

sc-bb

Structures

Sequence Color

Gα, Gβ, Gγ, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Search:

Interaction type	GPCR Segment	AA	Number	Generic number	Gα segment	AA	Number	Generic number

Interaction type	GPCR Segment	AA	Number	Generic number	Gα segment	AA	Number	Generic number

Hydrophobic	ICL2	Q	134	34x54	G.S3	L	194	G.S3.01
Hydrophobic	ICL2	P	130	34x50	G.H5	T	340	G.H5.12
Hydrophobic	TM4	S	140	4x40	G.HN	E	28	G.HN.52
Hydrophobic	TM3	C	126	3x53	G.H5	N	347	G.H5.19
Hydrophobic	ICL3	K	235	-	G.h4s6	E	318	G.h4s6.12
Hydrophobic	TM2	T	60	2x39	G.H5	D	350	G.H5.22
Hydrophobic	ICL3	M	233	-	G.H5	F	354	G.H5.26
Hydrophobic	ICL2	V	131	34x51	G.S3	L	194	G.S3.01
Hydrophobic	ICL2	Q	134	34x54	G.S1	V	34	G.S1.02
Hydrophobic	TM5	I	224	5x61	G.H5	L	353	G.H5.25
Hydrophobic	TM4	T	138	4x38	G.HN	E	28	G.HN.52
Hydrophobic	ICL2	P	130	34x50	G.H5	I	343	G.H5.15
Hydrophobic	ICL2	Q	134	34x54	G.hns1	R	32	G.hns1.03
Hydrophobic	ICL3	M	233	-	G.H5	K	345	G.H5.17
Hydrophobic	TM2	T	60	2x39	G.H5	C	351	G.H5.23
Hydrophobic	H8	G	306	8x47	G.H5	G	352	G.H5.24
Hydrophobic	TM3	V	127	3x54	G.H5	I	344	G.H5.16
Hydrophobic	ICL2	N	135	34x55	G.hns1	R	32	G.hns1.03
Hydrophobic	TM6	V	242	6x36	G.H5	L	353	G.H5.25
Hydrophobic	ICL3	I	234	-	G.H5	F	354	G.H5.26
Hydrophobic	TM3	V	127	3x54	G.H5	L	348	G.H5.20
Hydrophobic	TM3	R	123	3x50	G.H5	C	351	G.H5.23
Hydrophobic	ICL2	V	131	34x51	G.H5	F	336	G.H5.08
Hydrophobic	ICL2	V	131	34x51	G.s2s3	D	193	G.s2s3.02
Hydrophobic	TM6	P	239	6x33	G.H5	F	354	G.H5.26
Hydrophobic	TM7	V	305	7x56	G.H5	G	352	G.H5.24
Hydrophobic	ICL2	Q	134	34x54	G.H5	I	343	G.H5.15
Hydrophobic	TM5	I	228	5x65	G.H5	L	348	G.H5.20
Hydrophobic	ICL3	M	233	-	G.H5	I	344	G.H5.16
Hydrophobic	ICL2	P	130	34x50	G.H5	I	344	G.H5.16
Hydrophobic	TM6	R	238	6x32	G.H5	F	354	G.H5.26
Hydrophobic	TM6	L	243	6x37	G.H5	L	353	G.H5.25
Hydrophobic	TM6	P	239	6x33	G.H5	L	353	G.H5.25
Ionic	ICL3	K	235	-	G.h4s6	E	318	G.h4s6.12
Ionic	TM5	K	231	5x68	G.H5	D	341	G.H5.13
Ionic	H8	D	308	8x49	G.H5	K	349	G.H5.21
Polar	TM4	S	140	4x40	G.HN	E	28	G.HN.52
Polar	TM3	C	126	3x53	G.H5	N	347	G.H5.19
Polar	ICL3	K	235	-	G.h4s6	E	318	G.h4s6.12
Polar	TM2	T	60	2x39	G.H5	D	350	G.H5.22
Polar	TM5	K	231	5x68	G.H5	D	341	G.H5.13
Polar	TM4	V	139	4x39	G.HN	E	28	G.HN.52
Polar	TM4	T	138	4x38	G.HN	E	28	G.HN.52
Polar	ICL2	Q	134	34x54	G.hns1	A	31	G.hns1.02
Polar	ICL2	Q	134	34x54	G.hns1	R	32	G.hns1.03
Polar	ICL2	N	135	34x55	G.hns1	R	32	G.hns1.03
Polar	TM2	Y	64	2x43	G.H5	C	351	G.H5.23
Polar	TM6	R	238	6x32	G.H5	L	353	G.H5.25
Polar	TM3	R	123	3x50	G.H5	C	351	G.H5.23
Polar	H8	D	308	8x49	G.H5	K	349	G.H5.21
Polar	ICL2	N	135	34x55	G.s2s3	D	193	G.s2s3.02
Polar	TM6	P	239	6x33	G.H5	L	353	G.H5.25
Van-der-waals	ICL2	Q	134	34x54	G.S3	L	194	G.S3.01
Van-der-waals	ICL2	P	130	34x50	G.H5	T	340	G.H5.12
Van-der-waals	TM4	S	140	4x40	G.HN	E	28	G.HN.52
Van-der-waals	ICL3	K	235	-	G.h4s6	E	318	G.h4s6.12
Van-der-waals	ICL3	M	233	-	G.H5	F	354	G.H5.26
Van-der-waals	ICL2	Q	134	34x54	G.hns1	R	32	G.hns1.03
Van-der-waals	ICL3	M	233	-	G.H5	K	345	G.H5.17
Van-der-waals	TM3	V	127	3x54	G.H5	I	344	G.H5.16
Van-der-waals	ICL2	N	135	34x55	G.hns1	R	32	G.hns1.03
Van-der-waals	TM2	Y	64	2x43	G.H5	C	351	G.H5.23
Van-der-waals	TM6	R	238	6x32	G.H5	L	353	G.H5.25
Van-der-waals	TM3	V	127	3x54	G.H5	L	348	G.H5.20
Van-der-waals	TM3	R	123	3x50	G.H5	C	351	G.H5.23
Van-der-waals	ICL2	V	131	34x51	G.H5	F	336	G.H5.08
Van-der-waals	ICL2	V	131	34x51	G.s2s3	D	193	G.s2s3.02
Van-der-waals	TM6	P	239	6x33	G.H5	F	354	G.H5.26
Van-der-waals	ICL2	Q	134	34x54	G.H5	I	343	G.H5.15
Van-der-waals	TM5	I	228	5x65	G.H5	L	348	G.H5.20
Van-der-waals	ICL2	N	135	34x55	G.s2s3	D	193	G.s2s3.02
Van-der-waals	TM6	P	239	6x33	G.H5	L	353	G.H5.25

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Main reference

Refined structure (6OMM) of Gi1 - FPR2/ALX Download Full

GPCR CLASS (FAMILY)

SPECIES

G PROTEIN FAMILY

DATE

3D VIEW

REFINED G PROTEIN RESIDUES

REFINED GPCR RESIDUES

GPCR - G protein interface interactions

Structures

Refined structure (6OMM) of G_i1 - FPR2/ALX

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