Refined structure (7VVN) of Gs - PTH1 receptor

GPCR CLASS (FAMILY)

B1 (Secretin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

Gs

DATE

2024-02-01

3D VIEW

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Structure
GPCR
Gα
Gβ
Gγ
Model
AlphaFold2-Multimer

REFINED G PROTEIN RESIDUES

Residue backbones - 230 from structure (58.4%), 164 from model (41.6%)
Residue sidechains - 208 from structure (52.8%), 186 from model (47.2%)
Segment Seq.num. AA CGN# Backbone from Sidechain from
G.HN 1 M G.HN.01 AF2 AF2
G.HN 2 G G.HN.02 AF2 AF2
G.HN 3 C G.HN.09 AF2 AF2
G.HN 4 L G.HN.10 AF2 AF2
G.HN 5 G G.HN.11 AF2 AF2
G.HN 6 N G.HN.22 AF2 AF2
G.HN 7 S G.HN.23 AF2 AF2
G.HN 8 K G.HN.24 AF2 AF2
G.HN 9 T G.HN.26 AF2 AF2
G.HN 10 E G.HN.27 AF2 AF2
G.HN 11 D G.HN.28 AF2 AF2
G.HN 12 Q G.HN.29 Structure Structure
G.HN 13 R G.HN.30 Structure AF2
G.HN 14 N G.HN.31 Structure Structure
G.HN 15 E G.HN.32 Structure AF2
G.HN 16 E G.HN.33 Structure AF2
G.HN 17 K G.HN.34 Structure AF2
G.HN 18 A G.HN.35 Structure Structure
G.HN 19 Q G.HN.36 Structure Structure
G.HN 20 R G.HN.37 Structure AF2
G.HN 21 E G.HN.38 Structure AF2
G.HN 22 A G.HN.39 Structure Structure
G.HN 23 N G.HN.40 Structure Structure
G.HN 24 K G.HN.41 Structure AF2
G.HN 25 K G.HN.42 Structure Structure
G.HN 26 I G.HN.43 Structure Structure
G.HN 27 E G.HN.44 Structure Structure
G.HN 28 K G.HN.45 Structure Structure
G.HN 29 Q G.HN.46 Structure Structure
G.HN 30 L G.HN.47 Structure Structure
G.HN 31 Q G.HN.48 Structure Structure
G.HN 32 K G.HN.49 Structure AF2
G.HN 33 D G.HN.50 Structure Structure
G.HN 34 K G.HN.51 Structure Structure
G.HN 35 Q G.HN.52 Structure Structure
G.HN 36 V G.HN.53 Structure Structure
G.hns1 37 Y G.hns1.01 Structure Structure
G.hns1 38 R G.hns1.02 Structure Structure
G.hns1 39 A G.hns1.03 Structure Structure
G.S1 40 T G.S1.01 Structure Structure
G.S1 41 H G.S1.02 Structure Structure
G.S1 42 R G.S1.03 Structure Structure
G.S1 43 L G.S1.04 Structure Structure
G.S1 44 L G.S1.05 Structure Structure
G.S1 45 L G.S1.06 Structure Structure
G.S1 46 L G.S1.07 Structure Structure
G.s1h1 47 G G.s1h1.01 Structure Structure
G.s1h1 48 A G.s1h1.02 Structure Structure
G.s1h1 49 G G.s1h1.03 Structure AF2
G.s1h1 50 E G.s1h1.04 Structure AF2
G.s1h1 51 S G.s1h1.05 Structure Structure
G.s1h1 52 G G.s1h1.06 Structure Structure
G.H1 53 K G.H1.01 Structure Structure
G.H1 54 S G.H1.02 Structure Structure
G.H1 55 T G.H1.03 Structure Structure
G.H1 56 I G.H1.04 Structure Structure
G.H1 57 V G.H1.05 Structure Structure
G.H1 58 K G.H1.06 Structure AF2
G.H1 59 Q G.H1.07 Structure Structure
G.H1 60 M G.H1.08 Structure Structure
G.H1 61 R G.H1.09 Structure Structure
G.H1 62 I G.H1.10 Structure AF2
G.H1 63 L G.H1.11 AF2 AF2
G.H1 64 H G.H1.12 AF2 AF2
G.h1ha 65 V G.h1ha.01 AF2 AF2
G.h1ha 66 N G.h1ha.02 AF2 AF2
G.h1ha 67 G G.h1ha.03 AF2 AF2
G.h1ha 68 F G.h1ha.04 AF2 AF2
G.h1ha 69 N G.h1ha.05 AF2 AF2
G.h1ha 70 G G.h1ha.06 AF2 AF2
G.h1ha 71 E G.h1ha.07 AF2 AF2
G.h1ha 72 G G.h1ha.08 AF2 AF2
G.h1ha 73 G G.h1ha.09 AF2 AF2
G.h1ha 74 E G.h1ha.10 AF2 AF2
G.h1ha 75 E G.h1ha.11 AF2 AF2
G.h1ha 76 D G.h1ha.12 AF2 AF2
G.h1ha 77 P G.h1ha.13 AF2 AF2
G.h1ha 78 Q G.h1ha.14 AF2 AF2
G.h1ha 79 A G.h1ha.15 AF2 AF2
G.h1ha 80 A G.h1ha.16 AF2 AF2
G.h1ha 81 R G.h1ha.17 AF2 AF2
G.h1ha 82 S G.h1ha.18 AF2 AF2
G.h1ha 83 N G.h1ha.19 AF2 AF2
G.h1ha 84 S G.h1ha.20 AF2 AF2
H.HA 85 D H.HA.01 AF2 AF2
H.HA 86 G H.HA.02 AF2 AF2
H.HA 87 E H.HA.03 AF2 AF2
H.HA 88 K H.HA.04 AF2 AF2
H.HA 89 A H.HA.05 AF2 AF2
H.HA 90 T H.HA.06 AF2 AF2
H.HA 91 K H.HA.07 AF2 AF2
H.HA 92 V H.HA.08 AF2 AF2
H.HA 93 Q H.HA.09 AF2 AF2
H.HA 94 D H.HA.10 AF2 AF2
H.HA 95 I H.HA.11 AF2 AF2
H.HA 96 K H.HA.12 AF2 AF2
H.HA 97 N H.HA.13 AF2 AF2
H.HA 98 N H.HA.14 AF2 AF2
H.HA 99 L H.HA.15 AF2 AF2
H.HA 100 K H.HA.16 AF2 AF2
H.HA 101 E H.HA.17 AF2 AF2
H.HA 102 A H.HA.18 AF2 AF2
H.HA 103 I H.HA.19 AF2 AF2
H.HA 104 E H.HA.20 AF2 AF2
H.HA 105 T H.HA.21 AF2 AF2
H.HA 106 I H.HA.22 AF2 AF2
H.HA 107 V H.HA.23 AF2 AF2
H.HA 108 A H.HA.24 AF2 AF2
H.HA 109 A H.HA.25 AF2 AF2
H.HA 110 M H.HA.26 AF2 AF2
H.HA 111 S H.HA.27 AF2 AF2
H.HA 112 N H.HA.28 AF2 AF2
H.HA 113 L H.HA.29 AF2 AF2
H.hahb 114 V H.hahb.01 AF2 AF2
H.hahb 115 P H.hahb.02 AF2 AF2
H.hahb 116 P H.hahb.03 AF2 AF2
H.hahb 117 V H.hahb.04 AF2 AF2
H.hahb 118 E H.hahb.05 AF2 AF2
H.hahb 119 L H.hahb.06 AF2 AF2
H.hahb 120 A H.hahb.07 AF2 AF2
H.hahb 121 N H.hahb.08 AF2 AF2
H.hahb 122 P H.hahb.09 AF2 AF2
H.HB 123 E H.HB.01 AF2 AF2
H.HB 124 N H.HB.02 AF2 AF2
H.HB 125 Q H.HB.03 AF2 AF2
H.HB 126 F H.HB.04 AF2 AF2
H.HB 127 R H.HB.05 AF2 AF2
H.HB 128 V H.HB.06 AF2 AF2
H.HB 129 D H.HB.07 AF2 AF2
H.HB 130 Y H.HB.08 AF2 AF2
H.HB 131 I H.HB.09 AF2 AF2
H.HB 132 L H.HB.10 AF2 AF2
H.HB 133 S H.HB.11 AF2 AF2
H.HB 134 V H.HB.12 AF2 AF2
H.HB 135 M H.HB.13 AF2 AF2
H.HB 136 N H.HB.14 AF2 AF2
H.hbhc 137 V H.hbhc.01 AF2 AF2
H.hbhc 138 P H.hbhc.02 AF2 AF2
H.hbhc 139 D H.hbhc.03 AF2 AF2
H.hbhc 140 F H.hbhc.04 AF2 AF2
H.hbhc 141 D H.hbhc.13 AF2 AF2
H.hbhc 142 F H.hbhc.14 AF2 AF2
H.hbhc 143 P H.hbhc.15 AF2 AF2
H.HC 144 P H.HC.01 AF2 AF2
H.HC 145 E H.HC.02 AF2 AF2
H.HC 146 F H.HC.03 AF2 AF2
H.HC 147 Y H.HC.04 AF2 AF2
H.HC 148 E H.HC.05 AF2 AF2
H.HC 149 H H.HC.06 AF2 AF2
H.HC 150 A H.HC.07 AF2 AF2
H.HC 151 K H.HC.08 AF2 AF2
H.HC 152 A H.HC.09 AF2 AF2
H.HC 153 L H.HC.10 AF2 AF2
H.HC 154 W H.HC.11 AF2 AF2
H.HC 155 E H.HC.12 AF2 AF2
H.hchd 156 D H.hchd.01 AF2 AF2
H.HD 157 E H.HD.01 AF2 AF2
H.HD 158 G H.HD.02 AF2 AF2
H.HD 159 V H.HD.03 AF2 AF2
H.HD 160 R H.HD.04 AF2 AF2
H.HD 161 A H.HD.05 AF2 AF2
H.HD 162 C H.HD.06 AF2 AF2
H.HD 163 Y H.HD.07 AF2 AF2
H.HD 164 E H.HD.08 AF2 AF2
H.HD 165 R H.HD.09 AF2 AF2
H.HD 166 S H.HD.10 AF2 AF2
H.HD 167 N H.HD.11 AF2 AF2
H.HD 168 E H.HD.12 AF2 AF2
H.hdhe 169 Y H.hdhe.01 AF2 AF2
H.hdhe 170 Q H.hdhe.02 AF2 AF2
H.hdhe 171 L H.hdhe.03 AF2 AF2
H.hdhe 172 I H.hdhe.04 AF2 AF2
H.hdhe 173 D H.hdhe.05 AF2 AF2
H.HE 174 C H.HE.01 AF2 AF2
H.HE 175 A H.HE.02 AF2 AF2
H.HE 176 Q H.HE.03 AF2 AF2
H.HE 177 Y H.HE.04 AF2 AF2
H.HE 178 F H.HE.05 AF2 AF2
H.HE 179 L H.HE.06 AF2 AF2
H.HE 180 D H.HE.07 AF2 AF2
H.HE 181 K H.HE.08 AF2 AF2
H.HE 182 I H.HE.09 AF2 AF2
H.HE 183 D H.HE.10 AF2 AF2
H.HE 184 V H.HE.11 AF2 AF2
H.HE 185 I H.HE.12 AF2 AF2
H.HE 186 K H.HE.13 AF2 AF2
H.hehf 187 Q H.hehf.01 AF2 AF2
H.hehf 188 A H.hehf.02 AF2 AF2
H.hehf 189 D H.hehf.03 AF2 AF2
H.hehf 190 Y H.hehf.04 AF2 AF2
H.hehf 191 V H.hehf.05 AF2 AF2
H.hehf 192 P H.hehf.06 AF2 AF2
H.hehf 193 S H.hehf.07 AF2 AF2
H.HF 194 D H.HF.01 AF2 AF2
H.HF 195 Q H.HF.02 AF2 AF2
H.HF 196 D H.HF.03 AF2 AF2
H.HF 197 L H.HF.04 AF2 AF2
H.HF 198 L H.HF.05 AF2 AF2
H.HF 199 R H.HF.06 AF2 AF2
G.hfs2 200 C G.hfs2.01 AF2 AF2
G.hfs2 201 R G.hfs2.02 AF2 AF2
G.hfs2 202 V G.hfs2.03 AF2 AF2
G.hfs2 203 L G.hfs2.04 AF2 AF2
G.hfs2 204 T G.hfs2.05 AF2 AF2
G.hfs2 205 S G.hfs2.06 AF2 AF2
G.hfs2 206 G G.hfs2.07 Structure Structure
G.S2 207 I G.S2.01 Structure Structure
G.S2 208 F G.S2.02 Structure Structure
G.S2 209 E G.S2.03 Structure AF2
G.S2 210 T G.S2.04 Structure Structure
G.S2 211 K G.S2.05 Structure Structure
G.S2 212 F G.S2.06 Structure Structure
G.S2 213 Q G.S2.07 Structure Structure
G.S2 214 V G.S2.08 Structure Structure
G.s2s3 215 D G.s2s3.01 Structure Structure
G.s2s3 216 K G.s2s3.02 Structure Structure
G.S3 217 V G.S3.01 Structure Structure
G.S3 218 N G.S3.02 Structure Structure
G.S3 219 F G.S3.03 Structure Structure
G.S3 220 H G.S3.04 Structure Structure
G.S3 221 M G.S3.05 Structure Structure
G.S3 222 F G.S3.06 Structure Structure
G.S3 223 D G.S3.07 Structure Structure
G.S3 224 V G.S3.08 Structure Structure
G.s3h2 225 G G.s3h2.01 Structure Structure
G.s3h2 226 G G.s3h2.02 Structure Structure
G.s3h2 227 Q G.s3h2.03 Structure Structure
G.H2 228 R G.H2.01 Structure Structure
G.H2 229 D G.H2.02 Structure Structure
G.H2 230 E G.H2.03 Structure Structure
G.H2 231 R G.H2.04 Structure Structure
G.H2 232 R G.H2.05 Structure Structure
G.H2 233 K G.H2.06 Structure Structure
G.H2 234 W G.H2.07 Structure Structure
G.H2 235 I G.H2.08 Structure Structure
G.H2 236 Q G.H2.09 Structure Structure
G.H2 237 C G.H2.10 Structure Structure
G.h2s4 238 F G.h2s4.01 Structure Structure
G.h2s4 239 N G.h2s4.02 Structure Structure
G.h2s4 240 D G.h2s4.03 Structure Structure
G.h2s4 241 V G.h2s4.04 Structure Structure
G.h2s4 242 T G.h2s4.05 Structure Structure
G.S4 243 A G.S4.01 Structure Structure
G.S4 244 I G.S4.02 Structure Structure
G.S4 245 I G.S4.03 Structure Structure
G.S4 246 F G.S4.04 Structure Structure
G.S4 247 V G.S4.05 Structure Structure
G.S4 248 V G.S4.06 Structure Structure
G.S4 249 A G.S4.07 Structure AF2
G.s4h3 250 S G.s4h3.01 Structure Structure
G.s4h3 251 S G.s4h3.02 Structure Structure
G.s4h3 252 S G.s4h3.03 Structure AF2
G.s4h3 253 Y G.s4h3.04 Structure Structure
G.s4h3 254 N G.s4h3.05 Structure Structure
G.s4h3 255 M G.s4h3.06 AF2 AF2
G.s4h3 256 V G.s4h3.07 AF2 AF2
G.s4h3 257 I G.s4h3.08 AF2 AF2
G.s4h3 258 R G.s4h3.09 AF2 AF2
G.s4h3 259 E G.s4h3.10 AF2 AF2
G.s4h3 260 D G.s4h3.11 AF2 AF2
G.s4h3 261 N G.s4h3.12 AF2 AF2
G.s4h3 262 Q G.s4h3.13 AF2 AF2
G.s4h3 263 T G.s4h3.14 AF2 AF2
G.s4h3 264 N G.s4h3.15 AF2 AF2
G.H3 265 R G.H3.01 Structure Structure
G.H3 266 L G.H3.02 Structure Structure
G.H3 267 Q G.H3.03 Structure Structure
G.H3 268 E G.H3.04 Structure Structure
G.H3 269 A G.H3.05 Structure Structure
G.H3 270 L G.H3.06 Structure Structure
G.H3 271 N G.H3.07 Structure Structure
G.H3 272 L G.H3.08 Structure Structure
G.H3 273 F G.H3.09 Structure Structure
G.H3 274 K G.H3.10 Structure Structure
G.H3 275 S G.H3.11 Structure Structure
G.H3 276 I G.H3.12 Structure Structure
G.H3 277 W G.H3.13 Structure Structure
G.H3 278 N G.H3.14 Structure Structure
G.H3 279 N G.H3.15 Structure Structure
G.H3 280 R G.H3.16 Structure Structure
G.H3 281 W G.H3.17 Structure Structure
G.H3 282 L G.H3.18 Structure Structure
G.h3s5 283 R G.h3s5.01 Structure Structure
G.h3s5 284 T G.h3s5.02 Structure Structure
G.h3s5 285 I G.h3s5.03 Structure Structure
G.S5 286 S G.S5.01 Structure Structure
G.S5 287 V G.S5.02 Structure Structure
G.S5 288 I G.S5.03 Structure Structure
G.S5 289 L G.S5.04 Structure Structure
G.S5 290 F G.S5.05 Structure Structure
G.S5 291 L G.S5.06 Structure Structure
G.S5 292 N G.S5.07 Structure Structure
G.s5hg 293 K G.s5hg.01 Structure Structure
G.HG 294 Q G.HG.01 Structure Structure
G.HG 295 D G.HG.02 Structure Structure
G.HG 296 L G.HG.03 Structure Structure
G.HG 297 L G.HG.04 Structure Structure
G.HG 298 A G.HG.05 Structure Structure
G.HG 299 E G.HG.06 Structure Structure
G.HG 300 K G.HG.07 Structure Structure
G.HG 301 V G.HG.08 Structure Structure
G.HG 302 L G.HG.09 Structure Structure
G.HG 303 A G.HG.10 Structure Structure
G.HG 304 G G.HG.11 Structure Structure
G.HG 305 K G.HG.12 Structure Structure
G.HG 306 S G.HG.13 Structure Structure
G.HG 307 K G.HG.14 Structure Structure
G.HG 308 I G.HG.15 Structure Structure
G.HG 309 E G.HG.16 Structure Structure
G.HG 310 D G.HG.17 Structure Structure
G.hgh4 311 Y G.hgh4.01 Structure Structure
G.hgh4 312 F G.hgh4.02 Structure Structure
G.hgh4 313 P G.hgh4.03 Structure Structure
G.hgh4 314 E G.hgh4.04 Structure Structure
G.hgh4 315 F G.hgh4.05 Structure Structure
G.hgh4 316 A G.hgh4.06 Structure Structure
G.hgh4 317 R G.hgh4.07 Structure AF2
G.hgh4 318 Y G.hgh4.08 Structure Structure
G.hgh4 319 T G.hgh4.09 Structure Structure
G.hgh4 320 T G.hgh4.10 Structure Structure
G.hgh4 321 P G.hgh4.11 Structure Structure
G.hgh4 322 E G.hgh4.12 Structure AF2
G.hgh4 323 D G.hgh4.13 Structure Structure
G.hgh4 324 A G.hgh4.14 Structure Structure
G.hgh4 325 T G.hgh4.15 Structure Structure
G.hgh4 326 P G.hgh4.16 Structure Structure
G.hgh4 327 E G.hgh4.17 Structure Structure
G.hgh4 328 P G.hgh4.18 Structure Structure
G.hgh4 329 G G.hgh4.19 Structure Structure
G.hgh4 330 E G.hgh4.20 Structure Structure
G.hgh4 331 D G.hgh4.21 Structure Structure
G.H4 332 P G.H4.01 Structure Structure
G.H4 333 R G.H4.02 Structure Structure
G.H4 334 V G.H4.03 Structure Structure
G.H4 335 T G.H4.04 Structure Structure
G.H4 336 R G.H4.05 Structure Structure
G.H4 337 A G.H4.06 Structure Structure
G.H4 338 K G.H4.07 Structure Structure
G.H4 339 Y G.H4.08 Structure Structure
G.H4 340 F G.H4.10 Structure Structure
G.H4 341 I G.H4.11 Structure Structure
G.H4 342 R G.H4.12 Structure Structure
G.H4 343 D G.H4.13 Structure Structure
G.H4 344 E G.H4.14 Structure Structure
G.H4 345 F G.H4.15 Structure Structure
G.H4 346 L G.H4.16 Structure Structure
G.H4 347 R G.H4.17 Structure Structure
G.h4s6 348 I G.h4s6.01 Structure Structure
G.h4s6 349 S G.h4s6.02 Structure Structure
G.h4s6 350 T G.h4s6.03 Structure Structure
G.h4s6 351 A G.h4s6.04 Structure Structure
G.h4s6 352 S G.h4s6.08 Structure Structure
G.h4s6 353 G G.h4s6.09 Structure Structure
G.h4s6 354 D G.h4s6.10 Structure AF2
G.h4s6 355 G G.h4s6.11 Structure Structure
G.h4s6 356 R G.h4s6.12 Structure Structure
G.h4s6 357 H G.h4s6.13 Structure Structure
G.h4s6 358 Y G.h4s6.20 Structure AF2
G.S6 359 C G.S6.01 Structure Structure
G.S6 360 Y G.S6.02 Structure Structure
G.S6 361 P G.S6.03 Structure Structure
G.S6 362 H G.S6.04 Structure Structure
G.S6 363 F G.S6.05 Structure Structure
G.s6h5 364 T G.s6h5.01 Structure Structure
G.s6h5 365 C G.s6h5.02 Structure Structure
G.s6h5 366 A G.s6h5.03 Structure Structure
G.s6h5 367 V G.s6h5.04 Structure Structure
G.s6h5 368 D G.s6h5.05 Structure Structure
G.H5 369 T G.H5.01 Structure Structure
G.H5 370 E G.H5.02 Structure Structure
G.H5 371 N G.H5.03 Structure Structure
G.H5 372 I G.H5.04 Structure AF2
G.H5 373 R G.H5.05 Structure Structure
G.H5 374 R G.H5.06 Structure Structure
G.H5 375 V G.H5.07 Structure AF2
G.H5 376 F G.H5.08 Structure Structure
G.H5 377 N G.H5.09 Structure Structure
G.H5 378 D G.H5.10 Structure Structure
G.H5 379 C G.H5.11 Structure Structure
G.H5 380 R G.H5.12 Structure Structure
G.H5 381 D G.H5.13 Structure Structure
G.H5 382 I G.H5.14 Structure Structure
G.H5 383 I G.H5.15 Structure Structure
G.H5 384 Q G.H5.16 Structure Structure
G.H5 385 R G.H5.17 Structure Structure
G.H5 386 M G.H5.18 Structure Structure
G.H5 387 H G.H5.19 Structure Structure
G.H5 388 L G.H5.20 Structure Structure
G.H5 389 R G.H5.21 Structure AF2
G.H5 390 Q G.H5.22 Structure Structure
G.H5 391 Y G.H5.23 Structure Structure
G.H5 392 E G.H5.24 Structure Structure
G.H5 393 L G.H5.25 Structure Structure
G.H5 394 L G.H5.26 Structure Structure

REFINED GPCR RESIDUES

Residue backbones - 300 from structure (60.2%), 198 from model (39.8%)
Residue sidechains - 238 from structure (47.8%), 260 from model (52.2%)
Segment Seq.num. AA GPCRdb# Backbone from Sidechain from
N-term 1 M - AF2 AF2
N-term 2 G - AF2 AF2
N-term 3 T - AF2 AF2
N-term 4 A - AF2 AF2
N-term 5 R - AF2 AF2
N-term 6 I - AF2 AF2
N-term 7 A - AF2 AF2
N-term 8 P - AF2 AF2
N-term 9 G - AF2 AF2
N-term 10 L - AF2 AF2
N-term 11 A - AF2 AF2
N-term 12 L - AF2 AF2
N-term 13 L - AF2 AF2
N-term 14 L - AF2 AF2
N-term 15 C - AF2 AF2
N-term 16 C - AF2 AF2
N-term 17 P - AF2 AF2
N-term 18 V - AF2 AF2
N-term 19 L - AF2 AF2
N-term 20 S - AF2 AF2
N-term 21 S - AF2 AF2
N-term 22 A - AF2 AF2
N-term 23 Y - AF2 AF2
N-term 24 A - AF2 AF2
N-term 25 L - AF2 AF2
N-term 26 V - AF2 AF2
N-term 27 D - AF2 AF2
N-term 28 A - AF2 AF2
N-term 29 D - AF2 AF2
N-term 30 D - AF2 AF2
N-term 31 V - AF2 AF2
N-term 32 M - AF2 AF2
N-term 33 T - Structure AF2
N-term 34 K - Structure AF2
N-term 35 E - Structure AF2
N-term 36 E - Structure AF2
N-term 37 Q - Structure AF2
N-term 38 I - Structure AF2
N-term 39 F - Structure AF2
N-term 40 L - Structure AF2
N-term 41 L - Structure AF2
N-term 42 H - Structure AF2
N-term 43 R - Structure AF2
N-term 44 A - Structure Structure
N-term 45 Q - Structure AF2
N-term 46 A - Structure Structure
N-term 47 Q - Structure AF2
N-term 48 C - Structure Structure
N-term 49 E - Structure AF2
N-term 50 K - AF2 AF2
N-term 51 R - AF2 AF2
N-term 52 L - AF2 AF2
N-term 53 K - AF2 AF2
N-term 54 E - AF2 AF2
N-term 55 V - AF2 AF2
N-term 56 L - AF2 AF2
N-term 57 Q - AF2 AF2
N-term 58 R - AF2 AF2
N-term 59 P - AF2 AF2
N-term 60 A - AF2 AF2
N-term 61 S - AF2 AF2
N-term 62 I - AF2 AF2
N-term 63 M - AF2 AF2
N-term 64 E - AF2 AF2
N-term 65 S - AF2 AF2
N-term 66 D - AF2 AF2
N-term 67 K - AF2 AF2
N-term 68 G - AF2 AF2
N-term 69 W - AF2 AF2
N-term 70 T - AF2 AF2
N-term 71 S - AF2 AF2
N-term 72 A - AF2 AF2
N-term 73 S - AF2 AF2
N-term 74 T - AF2 AF2
N-term 75 S - AF2 AF2
N-term 76 G - AF2 AF2
N-term 77 K - AF2 AF2
N-term 78 P - AF2 AF2
N-term 79 R - AF2 AF2
N-term 80 K - AF2 AF2
N-term 81 D - AF2 AF2
N-term 82 K - AF2 AF2
N-term 83 A - AF2 AF2
N-term 84 S - AF2 AF2
N-term 85 G - AF2 AF2
N-term 86 K - AF2 AF2
N-term 87 L - AF2 AF2
N-term 88 Y - AF2 AF2
N-term 89 P - AF2 AF2
N-term 90 E - AF2 AF2
N-term 91 S - AF2 AF2
N-term 92 E - AF2 AF2
N-term 93 E - AF2 AF2
N-term 94 D - AF2 AF2
N-term 95 K - AF2 AF2
N-term 96 E - AF2 AF2
N-term 97 A - AF2 AF2
N-term 98 P - AF2 AF2
N-term 99 T - AF2 AF2
N-term 100 G - AF2 AF2
N-term 101 S - AF2 AF2
N-term 102 R - AF2 AF2
N-term 103 Y - AF2 AF2
N-term 104 R - AF2 AF2
N-term 105 G - AF2 AF2
N-term 106 R - AF2 AF2
N-term 107 P - AF2 AF2
N-term 108 C - AF2 AF2
N-term 109 L - AF2 AF2
N-term 110 P - AF2 AF2
N-term 111 E - Structure AF2
N-term 112 W - Structure AF2
N-term 113 D - Structure AF2
N-term 114 H - Structure AF2
N-term 115 I - Structure AF2
N-term 116 L - Structure AF2
N-term 117 C - Structure Structure
N-term 118 W - AF2 AF2
N-term 119 P - AF2 AF2
N-term 120 L - AF2 AF2
N-term 121 G - AF2 AF2
N-term 122 A - AF2 AF2
N-term 123 P - AF2 AF2
N-term 124 G - AF2 AF2
N-term 125 E - AF2 AF2
N-term 126 V - AF2 AF2
N-term 127 V - AF2 AF2
N-term 128 A - AF2 AF2
N-term 129 V - Structure AF2
N-term 130 P - Structure Structure
N-term 131 C - Structure Structure
N-term 132 P - Structure Structure
N-term 133 D - Structure AF2
N-term 134 Y - Structure AF2
N-term 135 I - Structure AF2
N-term 136 Y - AF2 AF2
N-term 137 D - AF2 AF2
N-term 138 F - Structure AF2
N-term 139 N - Structure AF2
N-term 140 H - Structure AF2
N-term 141 K - Structure AF2
N-term 142 G - Structure Structure
N-term 143 H - Structure AF2
N-term 144 A - Structure Structure
N-term 145 Y - Structure AF2
N-term 146 R - Structure AF2
N-term 147 R - AF2 AF2
N-term 148 C - AF2 AF2
N-term 149 D - AF2 AF2
N-term 150 R - AF2 AF2
N-term 151 N - AF2 AF2
N-term 152 G - AF2 AF2
N-term 153 S - AF2 AF2
N-term 154 W - AF2 AF2
N-term 155 E - AF2 AF2
N-term 156 L - AF2 AF2
N-term 157 V - AF2 AF2
N-term 158 P - AF2 AF2
N-term 159 G - AF2 AF2
N-term 160 H - AF2 AF2
N-term 161 N - AF2 AF2
N-term 162 R - Structure AF2
N-term 163 T - Structure AF2
N-term 164 W - Structure AF2
N-term 165 A - Structure Structure
N-term 166 N - Structure AF2
N-term 167 Y - Structure AF2
N-term 168 S - Structure Structure
N-term 169 E - Structure AF2
N-term 170 C - Structure Structure
N-term 171 V - Structure AF2
N-term 172 K - Structure AF2
TM1 173 F 1.25x25 Structure Structure
TM1 174 L 1.26x26 Structure Structure
TM1 175 T 1.27x27 AF2 AF2
TM1 176 N 1.28x28 AF2 AF2
TM1 177 E 1.29x29 AF2 AF2
TM1 178 T 1.30x30 AF2 AF2
TM1 179 R 1.31x31 AF2 AF2
TM1 180 E 1.32x32 AF2 AF2
TM1 181 R 1.33x33 Structure Structure
TM1 182 E 1.34x34 Structure Structure
TM1 183 V 1.35x35 Structure Structure
TM1 184 F 1.36x36 Structure Structure
TM1 185 D 1.37x37 Structure Structure
TM1 186 R 1.38x38 Structure Structure
TM1 187 L 1.39x39 Structure Structure
TM1 188 G 1.40x40 Structure Structure
TM1 189 M 1.41x41 Structure Structure
TM1 190 I 1.42x42 Structure Structure
TM1 191 Y 1.43x43 Structure Structure
TM1 192 T 1.44x44 Structure Structure
TM1 193 V 1.45x45 Structure Structure
TM1 194 G 1.46x46 Structure Structure
TM1 195 Y 1.47x47 Structure Structure
TM1 196 S 1.48x48 Structure Structure
TM1 197 V 1.49x49 Structure Structure
TM1 198 S 1.50x50 Structure Structure
TM1 199 L 1.51x51 Structure Structure
TM1 200 A 1.52x52 Structure Structure
TM1 201 S 1.53x53 Structure Structure
TM1 202 L 1.54x54 Structure Structure
TM1 203 T 1.55x55 Structure Structure
TM1 204 V 1.56x56 Structure Structure
TM1 205 A 1.57x57 Structure Structure
TM1 206 V 1.58x58 Structure Structure
TM1 207 L 1.59x59 Structure Structure
TM1 208 I 1.60x60 Structure Structure
TM1 209 L 1.61x61 Structure Structure
TM1 210 A 1.62x62 Structure Structure
TM1 211 Y 1.63x63 Structure AF2
TM1 212 F 1.64x64 Structure AF2
ICL1 213 R 12.48x48 Structure AF2
ICL1 214 R 12.49x49 Structure AF2
ICL1 215 L 12.50x50 Structure AF2
ICL1 216 H 12.51x51 Structure AF2
TM2 217 C 2.44x44 Structure Structure
TM2 218 T 2.45x45 Structure AF2
TM2 219 R 2.46x46 Structure Structure
TM2 220 N 2.47x47 Structure Structure
TM2 221 Y 2.48x48 Structure AF2
TM2 222 I 2.49x49 Structure Structure
TM2 223 H 2.50x50 Structure Structure
TM2 224 M 2.51x51 Structure AF2
TM2 225 H 2.52x52 Structure Structure
TM2 226 L 2.53x53 Structure Structure
TM2 227 F 2.54x54 Structure Structure
TM2 228 L 2.55x55 Structure Structure
TM2 229 S 2.56x56 Structure Structure
TM2 230 F 2.57x57 Structure Structure
TM2 231 M 2.58x58 Structure Structure
TM2 232 L 2.59x59 Structure Structure
TM2 233 R 2.60x60 Structure Structure
TM2 234 A 2.61x61 Structure Structure
TM2 235 V 2.62x62 Structure Structure
TM2 236 S 2.63x63 Structure Structure
TM2 237 I 2.64x64 Structure Structure
TM2 238 F 2.65x65 Structure Structure
TM2 239 V 2.66x66 Structure Structure
TM2 240 K 2.67x67 Structure Structure
TM2 241 D 2.68x68 Structure Structure
TM2 242 A 2.69x69 Structure Structure
TM2 243 V 2.70x70 Structure Structure
TM2 244 L 2.71x71 Structure Structure
TM2 245 Y 2.72x72 AF2 AF2
TM2 246 S 2.73x73 AF2 AF2
TM2 247 G 2.74x74 AF2 AF2
TM2 248 A 2.75x75 AF2 AF2
TM2 249 T 2.76x76 AF2 AF2
ECL1 250 L - AF2 AF2
ECL1 251 D - AF2 AF2
ECL1 252 E - AF2 AF2
ECL1 253 A - AF2 AF2
ECL1 254 E - AF2 AF2
ECL1 255 R - AF2 AF2
ECL1 256 L - AF2 AF2
ECL1 257 T - AF2 AF2
ECL1 258 E - AF2 AF2
ECL1 259 E - AF2 AF2
ECL1 260 E - AF2 AF2
ECL1 261 L - AF2 AF2
ECL1 262 R - AF2 AF2
ECL1 263 A - AF2 AF2
ECL1 264 I - AF2 AF2
ECL1 265 A - AF2 AF2
ECL1 266 Q - AF2 AF2
ECL1 267 A - AF2 AF2
ECL1 268 P - AF2 AF2
ECL1 269 P - AF2 AF2
ECL1 270 P - AF2 AF2
ECL1 271 P - AF2 AF2
ECL1 272 A - AF2 AF2
ECL1 273 T - AF2 AF2
ECL1 274 A - AF2 AF2
ECL1 275 A - AF2 AF2
ECL1 276 A - AF2 AF2
TM3 277 G 3.25x25 AF2 AF2
TM3 278 Y 3.26x26 Structure Structure
TM3 279 A 3.27x27 Structure Structure
TM3 280 G 3.28x28 Structure Structure
TM3 281 C 3.29x29 Structure Structure
TM3 282 R 3.30x30 Structure AF2
TM3 283 V 3.31x31 Structure Structure
TM3 284 A 3.32x32 Structure Structure
TM3 285 V 3.33x33 Structure Structure
TM3 286 T 3.34x34 Structure Structure
TM3 287 F 3.35x35 Structure Structure
TM3 288 F 3.36x36 Structure Structure
TM3 289 L 3.37x37 Structure Structure
TM3 290 Y 3.38x38 Structure Structure
TM3 291 F 3.39x39 Structure Structure
TM3 292 L 3.40x40 Structure Structure
TM3 293 A 3.41x41 Structure Structure
TM3 294 T 3.42x42 Structure Structure
TM3 295 N 3.43x43 Structure Structure
TM3 296 Y 3.44x44 Structure Structure
TM3 297 Y 3.45x45 Structure Structure
TM3 298 W 3.46x46 Structure Structure
TM3 299 I 3.47x47 Structure Structure
TM3 300 L 3.48x48 Structure Structure
TM3 301 V 3.49x49 Structure Structure
TM3 302 E 3.50x50 Structure Structure
TM3 303 G 3.51x51 Structure Structure
TM3 304 L 3.52x52 Structure Structure
TM3 305 Y 3.53x53 Structure Structure
TM3 306 L 3.54x54 Structure Structure
TM3 307 H 3.55x55 Structure Structure
TM3 308 S 3.56x56 Structure Structure
TM3 309 L 3.57x57 Structure Structure
TM3 310 I 3.58x58 Structure Structure
TM3 311 F 3.59x59 Structure Structure
TM3 312 M 3.60x60 Structure Structure
ICL2 313 A - Structure Structure
ICL2 314 F - Structure Structure
ICL2 315 F - Structure AF2
TM4 316 S 4.37x38 Structure Structure
TM4 317 E 4.38x39 Structure Structure
TM4 318 K 4.39x40 Structure AF2
TM4 319 K 4.40x41 Structure AF2
TM4 320 Y 4.41x42 Structure AF2
TM4 321 L 4.42x43 Structure Structure
TM4 322 W 4.43x44 Structure AF2
TM4 323 G 4.44x45 Structure Structure
TM4 324 F 4.45x46 Structure Structure
TM4 325 T 4.46x47 Structure Structure
TM4 326 V 4.47x48 Structure Structure
TM4 327 F 4.48x49 Structure Structure
TM4 328 G 4.49x491 Structure Structure
TM4 329 W 4.50x50 Structure Structure
TM4 330 G 4.51x51 Structure Structure
TM4 331 L 4.52x52 Structure Structure
TM4 332 P 4.53x53 Structure Structure
TM4 333 A 4.54x54 Structure Structure
TM4 334 V 4.55x55 Structure Structure
TM4 335 F 4.56x56 Structure Structure
TM4 336 V 4.57x57 Structure Structure
TM4 337 A 4.58x58 Structure Structure
TM4 338 V 4.59x59 Structure Structure
TM4 339 W 4.60x60 Structure Structure
TM4 340 V 4.61x61 Structure Structure
TM4 341 S 4.62x62 Structure Structure
TM4 342 V 4.63x63 Structure AF2
TM4 343 R 4.64x64 Structure AF2
TM4 344 A 4.65x65 Structure Structure
TM4 345 T 4.66x66 Structure Structure
TM4 346 L 4.67x67 Structure AF2
TM4 347 A 4.68x68 Structure Structure
ECL2 348 N - Structure Structure
ECL2 349 T - Structure Structure
ECL2 350 G - Structure Structure
ECL2 351 C 45.50x50 Structure Structure
ECL2 352 W 45.51x51 Structure Structure
ECL2 353 D 45.52x52 AF2 AF2
ECL2 354 L - AF2 AF2
ECL2 355 S - AF2 AF2
ECL2 356 S - AF2 AF2
TM5 357 G 5.33x34 AF2 AF2
TM5 358 N 5.34x35 AF2 AF2
TM5 359 K 5.35x36 AF2 AF2
TM5 360 K 5.36x37 AF2 AF2
TM5 361 W 5.37x38 Structure Structure
TM5 362 I 5.38x381 Structure Structure
TM5 363 I 5.39x39 Structure Structure
TM5 364 Q 5.40x40 Structure Structure
TM5 365 V 5.41x41 Structure Structure
TM5 366 P 5.42x42 Structure Structure
TM5 367 I 5.43x43 Structure Structure
TM5 368 L 5.44x44 Structure Structure
TM5 369 A 5.45x45 Structure Structure
TM5 370 S 5.46x46 Structure Structure
TM5 371 I 5.47x47 Structure Structure
TM5 372 V 5.48x48 Structure Structure
TM5 373 L 5.49x49 Structure Structure
TM5 374 N 5.50x50 Structure Structure
TM5 375 F 5.51x51 Structure Structure
TM5 376 I 5.52x52 Structure Structure
TM5 377 L 5.53x53 Structure Structure
TM5 378 F 5.54x54 Structure Structure
TM5 379 I 5.55x55 Structure Structure
TM5 380 N 5.56x56 Structure Structure
TM5 381 I 5.57x57 Structure Structure
TM5 382 V 5.58x58 Structure Structure
TM5 383 R 5.59x59 Structure Structure
TM5 384 V 5.60x60 Structure Structure
TM5 385 L 5.61x61 Structure Structure
TM5 386 A 5.62x62 Structure Structure
TM5 387 T 5.63x63 Structure Structure
TM5 388 K 5.64x64 Structure Structure
TM5 389 L 5.65x65 Structure Structure
ICL3 390 R - Structure Structure
ICL3 391 E - Structure Structure
ICL3 392 T - Structure Structure
ICL3 393 N - AF2 AF2
ICL3 394 A - AF2 AF2
ICL3 395 G - AF2 AF2
ICL3 396 R - AF2 AF2
ICL3 397 C - AF2 AF2
TM6 398 D 6.30x30 AF2 AF2
TM6 399 T 6.31x31 AF2 AF2
TM6 400 R 6.32x32 Structure Structure
TM6 401 Q 6.33x33 Structure Structure
TM6 402 Q 6.34x34 Structure Structure
TM6 403 Y 6.35x35 Structure AF2
TM6 404 R 6.36x36 Structure Structure
TM6 405 K 6.37x37 Structure Structure
TM6 406 L 6.38x38 Structure Structure
TM6 407 L 6.39x39 Structure Structure
TM6 408 K 6.40x40 Structure Structure
TM6 409 S 6.41x41 Structure Structure
TM6 410 T 6.42x42 Structure Structure
TM6 411 L 6.43x43 Structure Structure
TM6 412 V 6.44x44 Structure Structure
TM6 413 L 6.45x45 Structure Structure
TM6 414 M 6.46x46 Structure Structure
TM6 415 P 6.47x47 Structure Structure
TM6 416 L 6.48x48 Structure Structure
TM6 417 F 6.49x49 Structure Structure
TM6 418 G 6.50x50 Structure Structure
TM6 419 V 6.51x51 Structure Structure
TM6 420 H 6.52x52 Structure Structure
TM6 421 Y 6.53x53 Structure Structure
TM6 422 I 6.54x54 Structure Structure
TM6 423 V 6.55x55 Structure Structure
TM6 424 F 6.56x56 Structure Structure
TM6 425 M 6.57x57 Structure AF2
TM6 426 A 6.58x58 Structure Structure
TM6 427 T 6.59x59 Structure Structure
ECL3 428 P - Structure Structure
ECL3 429 Y - Structure Structure
ECL3 430 T - Structure Structure
ECL3 431 E - AF2 AF2
ECL3 432 V - AF2 AF2
ECL3 433 S - AF2 AF2
TM7 434 G 7.32x31 AF2 AF2
TM7 435 T 7.33x32 AF2 AF2
TM7 436 L 7.34x33 Structure Structure
TM7 437 W 7.35x34 Structure AF2
TM7 438 Q 7.36x35 Structure Structure
TM7 439 V 7.37x36 Structure Structure
TM7 440 Q 7.38x37 Structure Structure
TM7 441 M 7.39x38 Structure AF2
TM7 442 H 7.40x39 Structure Structure
TM7 443 Y 7.41x40 Structure Structure
TM7 444 E 7.42x41 Structure Structure
TM7 445 M 7.43x42 Structure Structure
TM7 446 L 7.44x43 Structure Structure
TM7 447 F 7.45x44 Structure Structure
TM7 448 N 7.46x45 Structure Structure
TM7 449 S 7.47x46 Structure Structure
TM7 450 F 7.48x47 Structure Structure
TM7 451 Q 7.49x49 Structure Structure
TM7 452 G 7.50x50 Structure Structure
TM7 453 F 7.51x51 Structure Structure
TM7 454 F 7.52x52 Structure Structure
TM7 455 V 7.53x53 Structure Structure
TM7 456 A 7.54x54 Structure Structure
TM7 457 I 7.55x55 Structure Structure
TM7 458 I 7.56x56 Structure Structure
TM7 459 Y 7.57x57 Structure Structure
TM7 460 C 7.58x58 Structure Structure
TM7 461 F 7.59x59 Structure Structure
TM7 462 C 7.60x60 Structure Structure
H8 463 N 8.47x47 Structure Structure
H8 464 G 8.48x48 Structure Structure
H8 465 E 8.49x49 Structure Structure
H8 466 V 8.50x50 Structure Structure
H8 467 Q 8.51x51 Structure Structure
H8 468 A 8.52x52 Structure Structure
H8 469 E 8.53x53 Structure Structure
H8 470 I 8.54x54 Structure Structure
H8 471 K 8.55x55 Structure Structure
H8 472 K 8.56x56 Structure Structure
H8 473 S 8.57x57 Structure Structure
H8 474 W 8.58x58 Structure Structure
H8 475 S 8.59x59 Structure Structure
H8 476 R 8.60x60 Structure Structure
H8 477 W 8.61x61 Structure AF2
H8 478 T 8.62x62 Structure Structure
H8 479 L 8.63x63 Structure Structure
H8 480 A 8.64x64 Structure Structure
H8 481 L 8.65x65 AF2 AF2
H8 482 D 8.66x66 AF2 AF2
H8 483 F 8.67x67 AF2 AF2
H8 484 K 8.68x68 AF2 AF2
H8 485 R 8.69x69 AF2 AF2
H8 486 K 8.70x70 AF2 AF2
H8 487 A 8.71x71 AF2 AF2
H8 488 R 8.72x72 AF2 AF2
C-term 489 S - AF2 AF2
C-term 490 G - AF2 AF2
C-term 491 S - AF2 AF2
C-term 492 S - AF2 AF2
C-term 493 S - AF2 AF2
C-term 494 Y - AF2 AF2
C-term 495 S - AF2 AF2
C-term 496 Y - AF2 AF2
C-term 497 G - AF2 AF2
C-term 498 P - AF2 AF2



GPCR - G protein interface interactions



The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.


Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):





Structures

Sequence Color

Gα, Gβ, Gγ, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Interaction
type		 GPCR
Segment
AA
Number		 Generic
number		 Gα
segment
AA
Number		 Generic
number
Hydrophobic ICL2 F 314 - G.H5 F 376 G.H5.08
Van-der-waals ICL2 F 314 - G.H5 F 376 G.H5.08
Hydrophobic TM6 L 413 6x45 G.H5 L 393 G.H5.25
Van-der-waals TM6 L 413 6x45 G.H5 L 393 G.H5.25
Hydrophobic ICL3 N 393 - G.h4s6 Y 358 G.h4s6.20
Van-der-waals ICL3 N 393 - G.h4s6 Y 358 G.h4s6.20
Ionic ICL3 R 396 - G.H4 D 343 G.H4.13
Polar ICL3 R 396 - G.H4 D 343 G.H4.13
Hydrophobic ICL3 R 396 - G.H4 D 343 G.H4.13
Van-der-waals ICL3 R 396 - G.H4 D 343 G.H4.13
Hydrophobic TM5 L 385 5x61 G.H5 L 394 G.H5.26
Van-der-waals TM5 L 385 5x61 G.H5 L 394 G.H5.26
Hydrophobic TM3 I 310 3x58 G.H5 L 388 G.H5.20
Van-der-waals TM3 I 310 3x58 G.H5 L 388 G.H5.20
Hydrophobic ICL3 R 396 - G.H4 L 346 G.H4.16
Hydrophobic ICL3 A 394 - G.H4 L 346 G.H4.16
Van-der-waals ICL3 A 394 - G.H4 L 346 G.H4.16
Polar TM3 I 310 3x58 G.H5 Q 384 G.H5.16
Hydrophobic TM3 I 310 3x58 G.H5 Q 384 G.H5.16
Van-der-waals TM3 I 310 3x58 G.H5 Q 384 G.H5.16
Aromatic ICL2 F 314 - G.H5 R 380 G.H5.12
Hydrophobic ICL2 F 314 - G.H5 R 380 G.H5.12
Polar TM6 S 409 6x41 G.H5 L 393 G.H5.25
Hydrophobic TM6 S 409 6x41 G.H5 L 393 G.H5.25
Van-der-waals TM6 S 409 6x41 G.H5 L 393 G.H5.25
Hydrophobic TM3 L 306 3x54 G.H5 Y 391 G.H5.23
Van-der-waals TM3 L 306 3x54 G.H5 Y 391 G.H5.23
Polar ICL1 H 216 12x51 G.H5 Q 390 G.H5.22
Van-der-waals ICL1 H 216 12x51 G.H5 Q 390 G.H5.22
Hydrophobic TM5 K 388 5x64 G.H5 R 385 G.H5.17
Hydrophobic TM5 L 385 5x61 G.H5 L 393 G.H5.25
Van-der-waals TM5 L 385 5x61 G.H5 L 393 G.H5.25
Hydrophobic TM5 L 389 5x65 G.H5 L 394 G.H5.26
Hydrophobic ICL2 F 314 - G.H5 I 383 G.H5.15
Van-der-waals ICL2 F 314 - G.H5 I 383 G.H5.15
Aromatic ICL2 F 314 - G.S1 H 41 G.S1.02
Hydrophobic ICL2 F 314 - G.S1 H 41 G.S1.02
Hydrophobic ICL3 R 396 - G.H4 R 342 G.H4.12
Van-der-waals ICL3 R 396 - G.H4 R 342 G.H4.12
Ionic TM5 K 388 5x64 G.H5 D 381 G.H5.13
Polar TM5 K 388 5x64 G.H5 D 381 G.H5.13
Hydrophobic TM5 K 388 5x64 G.H5 D 381 G.H5.13
Hydrophobic ICL2 F 314 - G.H5 C 379 G.H5.11
Hydrophobic ICL3 R 396 - G.h4s6 T 350 G.h4s6.03
Hydrophobic TM5 L 385 5x61 G.H5 L 388 G.H5.20
Hydrophobic TM3 L 309 3x57 G.H5 Y 391 G.H5.23
Polar TM2 T 218 2x45 G.H5 Y 391 G.H5.23
Hydrophobic TM3 L 306 3x54 G.H5 L 393 G.H5.25
Van-der-waals TM3 L 306 3x54 G.H5 L 393 G.H5.25
Polar TM2 R 219 2x46 G.H5 Q 390 G.H5.22
Hydrophobic TM2 R 219 2x46 G.H5 Q 390 G.H5.22
Hydrophobic TM4 E 317 4x39 G.H5 H 387 G.H5.19
Hydrophobic TM5 I 381 5x57 G.H5 L 393 G.H5.25
Hydrophobic TM3 L 309 3x57 G.H5 H 387 G.H5.19
Van-der-waals TM3 L 309 3x57 G.H5 H 387 G.H5.19
Aromatic TM2 R 219 2x46 G.H5 Y 391 G.H5.23
Hydrophobic TM2 R 219 2x46 G.H5 Y 391 G.H5.23
Van-der-waals TM2 R 219 2x46 G.H5 Y 391 G.H5.23
Hydrophobic ICL2 F 314 - G.S3 V 217 G.S3.01
Van-der-waals ICL2 F 314 - G.S3 V 217 G.S3.01
Polar TM5 K 388 5x64 G.H5 Q 384 G.H5.16
Hydrophobic TM5 K 388 5x64 G.H5 Q 384 G.H5.16
Van-der-waals TM5 K 388 5x64 G.H5 Q 384 G.H5.16
Hydrophobic ICL3 T 392 - G.h4s6 Y 358 G.h4s6.20
Hydrophobic ICL2 A 313 - G.H5 R 380 G.H5.12
Polar TM3 M 312 3x60 G.H5 R 380 G.H5.12
Hydrophobic ICL3 N 393 - G.h4s6 T 350 G.h4s6.03
Van-der-waals ICL3 N 393 - G.h4s6 T 350 G.h4s6.03