Refined structure (8TB0) of Gs - GPR61

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

Gs

DATE

2024-07-12

3D VIEW

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Structure
GPCR
Gα
Gβ
Gγ
Model
AlphaFold2-Multimer

REFINED G PROTEIN RESIDUES

Residue backbones - 222 from structure (56.3%), 172 from model (43.7%)
Residue sidechains - 196 from structure (49.7%), 198 from model (50.3%)
Segment Seq.num. AA CGN# Backbone from Sidechain from
G.HN 1 M G.HN.01 AF2 AF2
G.HN 2 G G.HN.02 AF2 AF2
G.HN 3 C G.HN.09 AF2 AF2
G.HN 4 L G.HN.10 AF2 AF2
G.HN 5 G G.HN.11 AF2 AF2
G.HN 6 N G.HN.22 AF2 AF2
G.HN 7 S G.HN.23 AF2 AF2
G.HN 8 K G.HN.24 AF2 AF2
G.HN 9 T G.HN.26 AF2 AF2
G.HN 10 E G.HN.27 AF2 AF2
G.HN 11 D G.HN.28 AF2 AF2
G.HN 12 Q G.HN.29 Structure AF2
G.HN 13 R G.HN.30 Structure AF2
G.HN 14 N G.HN.31 Structure AF2
G.HN 15 E G.HN.32 Structure Structure
G.HN 16 E G.HN.33 Structure AF2
G.HN 17 K G.HN.34 Structure Structure
G.HN 18 A G.HN.35 Structure Structure
G.HN 19 Q G.HN.36 Structure AF2
G.HN 20 R G.HN.37 Structure AF2
G.HN 21 E G.HN.38 Structure Structure
G.HN 22 A G.HN.39 Structure AF2
G.HN 23 N G.HN.40 Structure AF2
G.HN 24 K G.HN.41 Structure Structure
G.HN 25 K G.HN.42 Structure AF2
G.HN 26 I G.HN.43 Structure Structure
G.HN 27 E G.HN.44 Structure Structure
G.HN 28 K G.HN.45 Structure Structure
G.HN 29 Q G.HN.46 Structure Structure
G.HN 30 L G.HN.47 Structure Structure
G.HN 31 Q G.HN.48 Structure Structure
G.HN 32 K G.HN.49 Structure Structure
G.HN 33 D G.HN.50 Structure Structure
G.HN 34 K G.HN.51 Structure Structure
G.HN 35 Q G.HN.52 Structure Structure
G.HN 36 V G.HN.53 Structure Structure
G.hns1 37 Y G.hns1.01 Structure Structure
G.hns1 38 R G.hns1.02 Structure Structure
G.hns1 39 A G.hns1.03 Structure Structure
G.S1 40 T G.S1.01 Structure Structure
G.S1 41 H G.S1.02 Structure Structure
G.S1 42 R G.S1.03 Structure Structure
G.S1 43 L G.S1.04 Structure Structure
G.S1 44 L G.S1.05 Structure Structure
G.S1 45 L G.S1.06 Structure Structure
G.S1 46 L G.S1.07 Structure Structure
G.s1h1 47 G G.s1h1.01 Structure Structure
G.s1h1 48 A G.s1h1.02 Structure Structure
G.s1h1 49 G G.s1h1.03 Structure Structure
G.s1h1 50 E G.s1h1.04 Structure Structure
G.s1h1 51 S G.s1h1.05 Structure Structure
G.s1h1 52 G G.s1h1.06 Structure Structure
G.H1 53 K G.H1.01 Structure Structure
G.H1 54 S G.H1.02 Structure AF2
G.H1 55 T G.H1.03 Structure Structure
G.H1 56 I G.H1.04 Structure Structure
G.H1 57 V G.H1.05 Structure Structure
G.H1 58 K G.H1.06 Structure AF2
G.H1 59 Q G.H1.07 Structure AF2
G.H1 60 M G.H1.08 AF2 AF2
G.H1 61 R G.H1.09 AF2 AF2
G.H1 62 I G.H1.10 AF2 AF2
G.H1 63 L G.H1.11 AF2 AF2
G.H1 64 H G.H1.12 AF2 AF2
G.h1ha 65 V G.h1ha.01 AF2 AF2
G.h1ha 66 N G.h1ha.02 AF2 AF2
G.h1ha 67 G G.h1ha.03 AF2 AF2
G.h1ha 68 F G.h1ha.04 AF2 AF2
G.h1ha 69 N G.h1ha.05 AF2 AF2
G.h1ha 70 G G.h1ha.06 AF2 AF2
G.h1ha 71 E G.h1ha.07 AF2 AF2
G.h1ha 72 G G.h1ha.08 AF2 AF2
G.h1ha 73 G G.h1ha.09 AF2 AF2
G.h1ha 74 E G.h1ha.10 AF2 AF2
G.h1ha 75 E G.h1ha.11 AF2 AF2
G.h1ha 76 D G.h1ha.12 AF2 AF2
G.h1ha 77 P G.h1ha.13 AF2 AF2
G.h1ha 78 Q G.h1ha.14 AF2 AF2
G.h1ha 79 A G.h1ha.15 AF2 AF2
G.h1ha 80 A G.h1ha.16 AF2 AF2
G.h1ha 81 R G.h1ha.17 AF2 AF2
G.h1ha 82 S G.h1ha.18 AF2 AF2
G.h1ha 83 N G.h1ha.19 AF2 AF2
G.h1ha 84 S G.h1ha.20 AF2 AF2
H.HA 85 D H.HA.01 AF2 AF2
H.HA 86 G H.HA.02 AF2 AF2
H.HA 87 E H.HA.03 AF2 AF2
H.HA 88 K H.HA.04 AF2 AF2
H.HA 89 A H.HA.05 AF2 AF2
H.HA 90 T H.HA.06 AF2 AF2
H.HA 91 K H.HA.07 AF2 AF2
H.HA 92 V H.HA.08 AF2 AF2
H.HA 93 Q H.HA.09 AF2 AF2
H.HA 94 D H.HA.10 AF2 AF2
H.HA 95 I H.HA.11 AF2 AF2
H.HA 96 K H.HA.12 AF2 AF2
H.HA 97 N H.HA.13 AF2 AF2
H.HA 98 N H.HA.14 AF2 AF2
H.HA 99 L H.HA.15 AF2 AF2
H.HA 100 K H.HA.16 AF2 AF2
H.HA 101 E H.HA.17 AF2 AF2
H.HA 102 A H.HA.18 AF2 AF2
H.HA 103 I H.HA.19 AF2 AF2
H.HA 104 E H.HA.20 AF2 AF2
H.HA 105 T H.HA.21 AF2 AF2
H.HA 106 I H.HA.22 AF2 AF2
H.HA 107 V H.HA.23 AF2 AF2
H.HA 108 A H.HA.24 AF2 AF2
H.HA 109 A H.HA.25 AF2 AF2
H.HA 110 M H.HA.26 AF2 AF2
H.HA 111 S H.HA.27 AF2 AF2
H.HA 112 N H.HA.28 AF2 AF2
H.HA 113 L H.HA.29 AF2 AF2
H.hahb 114 V H.hahb.01 AF2 AF2
H.hahb 115 P H.hahb.02 AF2 AF2
H.hahb 116 P H.hahb.03 AF2 AF2
H.hahb 117 V H.hahb.04 AF2 AF2
H.hahb 118 E H.hahb.05 AF2 AF2
H.hahb 119 L H.hahb.06 AF2 AF2
H.hahb 120 A H.hahb.07 AF2 AF2
H.hahb 121 N H.hahb.08 AF2 AF2
H.hahb 122 P H.hahb.09 AF2 AF2
H.HB 123 E H.HB.01 AF2 AF2
H.HB 124 N H.HB.02 AF2 AF2
H.HB 125 Q H.HB.03 AF2 AF2
H.HB 126 F H.HB.04 AF2 AF2
H.HB 127 R H.HB.05 AF2 AF2
H.HB 128 V H.HB.06 AF2 AF2
H.HB 129 D H.HB.07 AF2 AF2
H.HB 130 Y H.HB.08 AF2 AF2
H.HB 131 I H.HB.09 AF2 AF2
H.HB 132 L H.HB.10 AF2 AF2
H.HB 133 S H.HB.11 AF2 AF2
H.HB 134 V H.HB.12 AF2 AF2
H.HB 135 M H.HB.13 AF2 AF2
H.HB 136 N H.HB.14 AF2 AF2
H.hbhc 137 V H.hbhc.01 AF2 AF2
H.hbhc 138 P H.hbhc.02 AF2 AF2
H.hbhc 139 D H.hbhc.03 AF2 AF2
H.hbhc 140 F H.hbhc.04 AF2 AF2
H.hbhc 141 D H.hbhc.13 AF2 AF2
H.hbhc 142 F H.hbhc.14 AF2 AF2
H.hbhc 143 P H.hbhc.15 AF2 AF2
H.HC 144 P H.HC.01 AF2 AF2
H.HC 145 E H.HC.02 AF2 AF2
H.HC 146 F H.HC.03 AF2 AF2
H.HC 147 Y H.HC.04 AF2 AF2
H.HC 148 E H.HC.05 AF2 AF2
H.HC 149 H H.HC.06 AF2 AF2
H.HC 150 A H.HC.07 AF2 AF2
H.HC 151 K H.HC.08 AF2 AF2
H.HC 152 A H.HC.09 AF2 AF2
H.HC 153 L H.HC.10 AF2 AF2
H.HC 154 W H.HC.11 AF2 AF2
H.HC 155 E H.HC.12 AF2 AF2
H.hchd 156 D H.hchd.01 AF2 AF2
H.HD 157 E H.HD.01 AF2 AF2
H.HD 158 G H.HD.02 AF2 AF2
H.HD 159 V H.HD.03 AF2 AF2
H.HD 160 R H.HD.04 AF2 AF2
H.HD 161 A H.HD.05 AF2 AF2
H.HD 162 C H.HD.06 AF2 AF2
H.HD 163 Y H.HD.07 AF2 AF2
H.HD 164 E H.HD.08 AF2 AF2
H.HD 165 R H.HD.09 AF2 AF2
H.HD 166 S H.HD.10 AF2 AF2
H.HD 167 N H.HD.11 AF2 AF2
H.HD 168 E H.HD.12 AF2 AF2
H.hdhe 169 Y H.hdhe.01 AF2 AF2
H.hdhe 170 Q H.hdhe.02 AF2 AF2
H.hdhe 171 L H.hdhe.03 AF2 AF2
H.hdhe 172 I H.hdhe.04 AF2 AF2
H.hdhe 173 D H.hdhe.05 AF2 AF2
H.HE 174 C H.HE.01 AF2 AF2
H.HE 175 A H.HE.02 AF2 AF2
H.HE 176 Q H.HE.03 AF2 AF2
H.HE 177 Y H.HE.04 AF2 AF2
H.HE 178 F H.HE.05 AF2 AF2
H.HE 179 L H.HE.06 AF2 AF2
H.HE 180 D H.HE.07 AF2 AF2
H.HE 181 K H.HE.08 AF2 AF2
H.HE 182 I H.HE.09 AF2 AF2
H.HE 183 D H.HE.10 AF2 AF2
H.HE 184 V H.HE.11 AF2 AF2
H.HE 185 I H.HE.12 AF2 AF2
H.HE 186 K H.HE.13 AF2 AF2
H.hehf 187 Q H.hehf.01 AF2 AF2
H.hehf 188 A H.hehf.02 AF2 AF2
H.hehf 189 D H.hehf.03 AF2 AF2
H.hehf 190 Y H.hehf.04 AF2 AF2
H.hehf 191 V H.hehf.05 AF2 AF2
H.hehf 192 P H.hehf.06 AF2 AF2
H.hehf 193 S H.hehf.07 AF2 AF2
H.HF 194 D H.HF.01 AF2 AF2
H.HF 195 Q H.HF.02 AF2 AF2
H.HF 196 D H.HF.03 AF2 AF2
H.HF 197 L H.HF.04 AF2 AF2
H.HF 198 L H.HF.05 AF2 AF2
H.HF 199 R H.HF.06 AF2 AF2
G.hfs2 200 C G.hfs2.01 AF2 AF2
G.hfs2 201 R G.hfs2.02 AF2 AF2
G.hfs2 202 V G.hfs2.03 AF2 AF2
G.hfs2 203 L G.hfs2.04 AF2 AF2
G.hfs2 204 T G.hfs2.05 AF2 AF2
G.hfs2 205 S G.hfs2.06 AF2 AF2
G.hfs2 206 G G.hfs2.07 AF2 AF2
G.S2 207 I G.S2.01 Structure Structure
G.S2 208 F G.S2.02 Structure Structure
G.S2 209 E G.S2.03 Structure Structure
G.S2 210 T G.S2.04 Structure Structure
G.S2 211 K G.S2.05 Structure Structure
G.S2 212 F G.S2.06 Structure Structure
G.S2 213 Q G.S2.07 Structure Structure
G.S2 214 V G.S2.08 Structure Structure
G.s2s3 215 D G.s2s3.01 Structure Structure
G.s2s3 216 K G.s2s3.02 Structure AF2
G.S3 217 V G.S3.01 Structure Structure
G.S3 218 N G.S3.02 Structure Structure
G.S3 219 F G.S3.03 Structure Structure
G.S3 220 H G.S3.04 Structure Structure
G.S3 221 M G.S3.05 Structure Structure
G.S3 222 F G.S3.06 Structure Structure
G.S3 223 D G.S3.07 Structure Structure
G.S3 224 V G.S3.08 Structure Structure
G.s3h2 225 G G.s3h2.01 Structure Structure
G.s3h2 226 G G.s3h2.02 Structure AF2
G.s3h2 227 Q G.s3h2.03 Structure Structure
G.H2 228 R G.H2.01 Structure Structure
G.H2 229 D G.H2.02 Structure Structure
G.H2 230 E G.H2.03 Structure Structure
G.H2 231 R G.H2.04 Structure Structure
G.H2 232 R G.H2.05 Structure Structure
G.H2 233 K G.H2.06 Structure Structure
G.H2 234 W G.H2.07 Structure Structure
G.H2 235 I G.H2.08 Structure Structure
G.H2 236 Q G.H2.09 Structure Structure
G.H2 237 C G.H2.10 Structure Structure
G.h2s4 238 F G.h2s4.01 Structure Structure
G.h2s4 239 N G.h2s4.02 Structure Structure
G.h2s4 240 D G.h2s4.03 Structure AF2
G.h2s4 241 V G.h2s4.04 Structure Structure
G.h2s4 242 T G.h2s4.05 Structure Structure
G.S4 243 A G.S4.01 Structure Structure
G.S4 244 I G.S4.02 Structure Structure
G.S4 245 I G.S4.03 Structure Structure
G.S4 246 F G.S4.04 Structure Structure
G.S4 247 V G.S4.05 Structure Structure
G.S4 248 V G.S4.06 Structure Structure
G.S4 249 A G.S4.07 Structure Structure
G.s4h3 250 S G.s4h3.01 Structure Structure
G.s4h3 251 S G.s4h3.02 Structure Structure
G.s4h3 252 S G.s4h3.03 Structure Structure
G.s4h3 253 Y G.s4h3.04 AF2 AF2
G.s4h3 254 N G.s4h3.05 AF2 AF2
G.s4h3 255 M G.s4h3.06 AF2 AF2
G.s4h3 256 V G.s4h3.07 AF2 AF2
G.s4h3 257 I G.s4h3.08 AF2 AF2
G.s4h3 258 R G.s4h3.09 AF2 AF2
G.s4h3 259 E G.s4h3.10 AF2 AF2
G.s4h3 260 D G.s4h3.11 AF2 AF2
G.s4h3 261 N G.s4h3.12 AF2 AF2
G.s4h3 262 Q G.s4h3.13 AF2 AF2
G.s4h3 263 T G.s4h3.14 Structure Structure
G.s4h3 264 N G.s4h3.15 Structure Structure
G.H3 265 R G.H3.01 Structure Structure
G.H3 266 L G.H3.02 Structure Structure
G.H3 267 Q G.H3.03 Structure Structure
G.H3 268 E G.H3.04 Structure AF2
G.H3 269 A G.H3.05 Structure Structure
G.H3 270 L G.H3.06 Structure Structure
G.H3 271 N G.H3.07 Structure AF2
G.H3 272 L G.H3.08 Structure Structure
G.H3 273 F G.H3.09 Structure Structure
G.H3 274 K G.H3.10 Structure AF2
G.H3 275 S G.H3.11 Structure Structure
G.H3 276 I G.H3.12 Structure Structure
G.H3 277 W G.H3.13 Structure Structure
G.H3 278 N G.H3.14 Structure Structure
G.H3 279 N G.H3.15 Structure Structure
G.H3 280 R G.H3.16 Structure AF2
G.H3 281 W G.H3.17 Structure Structure
G.H3 282 L G.H3.18 Structure Structure
G.h3s5 283 R G.h3s5.01 Structure Structure
G.h3s5 284 T G.h3s5.02 Structure AF2
G.h3s5 285 I G.h3s5.03 Structure AF2
G.S5 286 S G.S5.01 Structure Structure
G.S5 287 V G.S5.02 Structure Structure
G.S5 288 I G.S5.03 Structure Structure
G.S5 289 L G.S5.04 Structure Structure
G.S5 290 F G.S5.05 Structure Structure
G.S5 291 L G.S5.06 Structure Structure
G.S5 292 N G.S5.07 Structure Structure
G.s5hg 293 K G.s5hg.01 Structure Structure
G.HG 294 Q G.HG.01 Structure Structure
G.HG 295 D G.HG.02 Structure Structure
G.HG 296 L G.HG.03 Structure Structure
G.HG 297 L G.HG.04 Structure Structure
G.HG 298 A G.HG.05 Structure Structure
G.HG 299 E G.HG.06 Structure Structure
G.HG 300 K G.HG.07 Structure AF2
G.HG 301 V G.HG.08 Structure Structure
G.HG 302 L G.HG.09 Structure Structure
G.HG 303 A G.HG.10 Structure Structure
G.HG 304 G G.HG.11 Structure Structure
G.HG 305 K G.HG.12 AF2 AF2
G.HG 306 S G.HG.13 AF2 AF2
G.HG 307 K G.HG.14 Structure AF2
G.HG 308 I G.HG.15 Structure Structure
G.HG 309 E G.HG.16 Structure Structure
G.HG 310 D G.HG.17 Structure Structure
G.hgh4 311 Y G.hgh4.01 Structure Structure
G.hgh4 312 F G.hgh4.02 Structure Structure
G.hgh4 313 P G.hgh4.03 Structure Structure
G.hgh4 314 E G.hgh4.04 Structure Structure
G.hgh4 315 F G.hgh4.05 Structure Structure
G.hgh4 316 A G.hgh4.06 Structure Structure
G.hgh4 317 R G.hgh4.07 Structure Structure
G.hgh4 318 Y G.hgh4.08 Structure Structure
G.hgh4 319 T G.hgh4.09 Structure Structure
G.hgh4 320 T G.hgh4.10 Structure Structure
G.hgh4 321 P G.hgh4.11 Structure Structure
G.hgh4 322 E G.hgh4.12 Structure AF2
G.hgh4 323 D G.hgh4.13 Structure Structure
G.hgh4 324 A G.hgh4.14 Structure Structure
G.hgh4 325 T G.hgh4.15 Structure Structure
G.hgh4 326 P G.hgh4.16 Structure Structure
G.hgh4 327 E G.hgh4.17 Structure Structure
G.hgh4 328 P G.hgh4.18 Structure Structure
G.hgh4 329 G G.hgh4.19 Structure Structure
G.hgh4 330 E G.hgh4.20 Structure Structure
G.hgh4 331 D G.hgh4.21 Structure Structure
G.H4 332 P G.H4.01 Structure Structure
G.H4 333 R G.H4.02 Structure Structure
G.H4 334 V G.H4.03 Structure Structure
G.H4 335 T G.H4.04 Structure Structure
G.H4 336 R G.H4.05 Structure Structure
G.H4 337 A G.H4.06 Structure Structure
G.H4 338 K G.H4.07 Structure Structure
G.H4 339 Y G.H4.08 Structure Structure
G.H4 340 F G.H4.10 Structure Structure
G.H4 341 I G.H4.11 Structure Structure
G.H4 342 R G.H4.12 Structure Structure
G.H4 343 D G.H4.13 Structure Structure
G.H4 344 E G.H4.14 Structure Structure
G.H4 345 F G.H4.15 Structure Structure
G.H4 346 L G.H4.16 Structure Structure
G.H4 347 R G.H4.17 Structure Structure
G.h4s6 348 I G.h4s6.01 Structure Structure
G.h4s6 349 S G.h4s6.02 Structure Structure
G.h4s6 350 T G.h4s6.03 Structure Structure
G.h4s6 351 A G.h4s6.04 Structure Structure
G.h4s6 352 S G.h4s6.08 Structure Structure
G.h4s6 353 G G.h4s6.09 Structure Structure
G.h4s6 354 D G.h4s6.10 Structure AF2
G.h4s6 355 G G.h4s6.11 Structure Structure
G.h4s6 356 R G.h4s6.12 Structure Structure
G.h4s6 357 H G.h4s6.13 Structure Structure
G.h4s6 358 Y G.h4s6.20 Structure Structure
G.S6 359 C G.S6.01 Structure Structure
G.S6 360 Y G.S6.02 Structure Structure
G.S6 361 P G.S6.03 Structure Structure
G.S6 362 H G.S6.04 Structure Structure
G.S6 363 F G.S6.05 Structure Structure
G.s6h5 364 T G.s6h5.01 Structure Structure
G.s6h5 365 C G.s6h5.02 Structure Structure
G.s6h5 366 A G.s6h5.03 AF2 AF2
G.s6h5 367 V G.s6h5.04 AF2 AF2
G.s6h5 368 D G.s6h5.05 Structure Structure
G.H5 369 T G.H5.01 Structure AF2
G.H5 370 E G.H5.02 Structure Structure
G.H5 371 N G.H5.03 Structure Structure
G.H5 372 I G.H5.04 Structure Structure
G.H5 373 R G.H5.05 Structure Structure
G.H5 374 R G.H5.06 Structure Structure
G.H5 375 V G.H5.07 Structure Structure
G.H5 376 F G.H5.08 Structure Structure
G.H5 377 N G.H5.09 Structure Structure
G.H5 378 D G.H5.10 Structure Structure
G.H5 379 C G.H5.11 Structure Structure
G.H5 380 R G.H5.12 Structure Structure
G.H5 381 D G.H5.13 Structure Structure
G.H5 382 I G.H5.14 Structure Structure
G.H5 383 I G.H5.15 Structure Structure
G.H5 384 Q G.H5.16 Structure Structure
G.H5 385 R G.H5.17 Structure Structure
G.H5 386 M G.H5.18 Structure Structure
G.H5 387 H G.H5.19 Structure Structure
G.H5 388 L G.H5.20 Structure Structure
G.H5 389 R G.H5.21 Structure Structure
G.H5 390 Q G.H5.22 Structure Structure
G.H5 391 Y G.H5.23 Structure Structure
G.H5 392 E G.H5.24 Structure Structure
G.H5 393 L G.H5.25 Structure Structure
G.H5 394 L G.H5.26 Structure Structure

REFINED GPCR RESIDUES

Residue backbones - 252 from structure (71.6%), 100 from model (28.4%)
Residue sidechains - 252 from structure (71.6%), 100 from model (28.4%)
Segment Seq.num. AA GPCRdb# Backbone from Sidechain from
N-term 1 M - AF2 AF2
N-term 2 E - AF2 AF2
N-term 3 S - AF2 AF2
N-term 4 S - AF2 AF2
N-term 5 P - AF2 AF2
N-term 6 I - AF2 AF2
N-term 7 P - AF2 AF2
N-term 8 Q - AF2 AF2
N-term 9 S - AF2 AF2
N-term 10 S - AF2 AF2
N-term 11 G - AF2 AF2
N-term 12 N - AF2 AF2
N-term 13 S - AF2 AF2
N-term 14 S - AF2 AF2
N-term 15 T - AF2 AF2
N-term 16 L - AF2 AF2
N-term 17 G - AF2 AF2
N-term 18 R - AF2 AF2
N-term 19 V - AF2 AF2
N-term 20 P - AF2 AF2
N-term 21 Q - AF2 AF2
N-term 22 T - AF2 AF2
N-term 23 P - AF2 AF2
N-term 24 G - AF2 AF2
N-term 25 P - AF2 AF2
N-term 26 S - AF2 AF2
N-term 27 T - AF2 AF2
N-term 28 A - AF2 AF2
N-term 29 S - AF2 AF2
N-term 30 G - AF2 AF2
N-term 31 V - AF2 AF2
N-term 32 P - AF2 AF2
N-term 33 E - AF2 AF2
N-term 34 V - AF2 AF2
N-term 35 G - AF2 AF2
TM1 36 L 1.26x26 AF2 AF2
TM1 37 R 1.27x27 AF2 AF2
TM1 38 D 1.28x28 AF2 AF2
TM1 39 V 1.29x29 AF2 AF2
TM1 40 A 1.30x30 AF2 AF2
TM1 41 S 1.31x31 AF2 AF2
TM1 42 E 1.32x32 AF2 AF2
TM1 43 S 1.33x33 AF2 AF2
TM1 44 V 1.34x34 AF2 AF2
TM1 45 A 1.35x35 Structure Structure
TM1 46 L 1.36x36 Structure Structure
TM1 47 F 1.37x37 Structure Structure
TM1 48 F 1.38x38 Structure Structure
TM1 49 M 1.39x39 Structure Structure
TM1 50 L 1.40x40 Structure Structure
TM1 51 L 1.41x41 Structure Structure
TM1 52 L 1.42x42 Structure Structure
TM1 53 D 1.43x43 Structure Structure
TM1 54 L 1.44x44 Structure Structure
TM1 55 T 1.45x45 Structure Structure
TM1 56 A 1.46x46 Structure Structure
TM1 57 V 1.47x47 Structure Structure
TM1 58 A 1.48x48 Structure Structure
TM1 59 G 1.49x49 Structure Structure
TM1 60 N 1.50x50 Structure Structure
TM1 61 A 1.51x51 Structure Structure
TM1 62 A 1.52x52 Structure Structure
TM1 63 V 1.53x53 Structure Structure
TM1 64 M 1.54x54 Structure Structure
TM1 65 A 1.55x55 Structure Structure
TM1 66 V 1.56x56 Structure Structure
TM1 67 I 1.57x57 Structure Structure
TM1 68 A 1.58x58 Structure Structure
TM1 69 K 1.59x59 Structure Structure
TM1 70 T 1.60x60 Structure Structure
ICL1 71 P 12.48x48 Structure Structure
ICL1 72 A 12.49x49 Structure Structure
ICL1 73 L 12.50x50 Structure Structure
ICL1 74 R 12.51x51 Structure Structure
TM2 75 K 2.39x39 Structure Structure
TM2 76 F 2.40x40 Structure Structure
TM2 77 V 2.41x41 Structure Structure
TM2 78 F 2.42x42 Structure Structure
TM2 79 V 2.43x43 Structure Structure
TM2 80 F 2.44x44 Structure Structure
TM2 81 H 2.45x45 Structure Structure
TM2 82 L 2.46x46 Structure Structure
TM2 83 C 2.47x47 Structure Structure
TM2 84 L 2.48x48 Structure Structure
TM2 85 V 2.49x49 Structure Structure
TM2 86 D 2.50x50 Structure Structure
TM2 87 L 2.51x51 Structure Structure
TM2 88 L 2.52x52 Structure Structure
TM2 89 A 2.53x53 Structure Structure
TM2 90 A 2.54x54 Structure Structure
TM2 91 L 2.55x55 Structure Structure
TM2 92 T 2.56x551 Structure Structure
TM2 93 L 2.57x56 Structure Structure
TM2 94 M 2.58x57 Structure Structure
TM2 95 P 2.59x58 Structure Structure
TM2 96 L 2.60x59 Structure Structure
TM2 97 A 2.61x60 Structure Structure
TM2 98 M 2.62x61 Structure Structure
TM2 99 L 2.63x62 Structure Structure
TM2 100 S 2.64x63 Structure Structure
TM2 101 S 2.65x64 Structure Structure
TM2 102 S 2.66x65 Structure Structure
TM2 103 A 2.67x66 Structure Structure
TM2 104 L 2.68x67 Structure Structure
ECL1 105 F - Structure Structure
ECL1 106 D 23.49x49 Structure Structure
ECL1 107 H 23.50x50 Structure Structure
ECL1 108 A 23.51x51 Structure Structure
ECL1 109 L 23.52x52 Structure Structure
TM3 110 F 3.20x20 Structure Structure
TM3 111 G 3.21x21 Structure Structure
TM3 112 E 3.22x22 Structure Structure
TM3 113 V 3.23x23 Structure Structure
TM3 114 A 3.24x24 Structure Structure
TM3 115 C 3.25x25 Structure Structure
TM3 116 R 3.26x26 Structure Structure
TM3 117 L 3.27x27 Structure Structure
TM3 118 Y 3.28x28 Structure Structure
TM3 119 L 3.29x29 Structure Structure
TM3 120 F 3.30x30 Structure Structure
TM3 121 L 3.31x31 Structure Structure
TM3 122 S 3.32x32 Structure Structure
TM3 123 V 3.33x33 Structure Structure
TM3 124 C 3.34x34 Structure Structure
TM3 125 F 3.35x35 Structure Structure
TM3 126 V 3.36x36 Structure Structure
TM3 127 S 3.37x37 Structure Structure
TM3 128 L 3.38x38 Structure Structure
TM3 129 A 3.39x39 Structure Structure
TM3 130 I 3.40x40 Structure Structure
TM3 131 L 3.41x41 Structure Structure
TM3 132 S 3.42x42 Structure Structure
TM3 133 V 3.43x43 Structure Structure
TM3 134 S 3.44x44 Structure Structure
TM3 135 A 3.45x45 Structure Structure
TM3 136 I 3.46x46 Structure Structure
TM3 137 N 3.47x47 Structure Structure
TM3 138 V 3.48x48 Structure Structure
TM3 139 E 3.49x49 Structure Structure
TM3 140 R 3.50x50 Structure Structure
TM3 141 Y 3.51x51 Structure Structure
TM3 142 Y 3.52x52 Structure Structure
TM3 143 Y 3.53x53 Structure Structure
TM3 144 V 3.54x54 Structure Structure
TM3 145 V 3.55x55 Structure Structure
TM3 146 H 3.56x56 Structure Structure
ICL2 147 P 34.50x50 Structure Structure
ICL2 148 M 34.51x51 Structure Structure
ICL2 149 R 34.52x52 Structure Structure
ICL2 150 Y 34.53x53 Structure Structure
ICL2 151 E 34.54x54 Structure Structure
ICL2 152 V 34.55x55 Structure Structure
ICL2 153 R 34.56x56 Structure Structure
ICL2 154 M 34.57x57 Structure Structure
TM4 155 T 4.38x38 Structure Structure
TM4 156 L 4.39x39 Structure Structure
TM4 157 G 4.40x40 Structure Structure
TM4 158 L 4.41x41 Structure Structure
TM4 159 V 4.42x42 Structure Structure
TM4 160 A 4.43x43 Structure Structure
TM4 161 S 4.44x44 Structure Structure
TM4 162 V 4.45x45 Structure Structure
TM4 163 L 4.46x46 Structure Structure
TM4 164 V 4.47x47 Structure Structure
TM4 165 G 4.48x48 Structure Structure
TM4 166 V 4.49x49 Structure Structure
TM4 167 W 4.50x50 Structure Structure
TM4 168 V 4.51x51 Structure Structure
TM4 169 K 4.52x52 Structure Structure
TM4 170 A 4.53x53 Structure Structure
TM4 171 L 4.54x54 Structure Structure
TM4 172 A 4.55x55 Structure Structure
TM4 173 M 4.56x56 Structure Structure
TM4 174 A 4.57x57 Structure Structure
TM4 175 S 4.58x58 Structure Structure
TM4 176 V 4.59x59 Structure Structure
TM4 177 P 4.60x60 Structure Structure
TM4 178 V 4.61x61 Structure Structure
TM4 179 L 4.62x62 Structure Structure
TM4 180 G 4.63x63 Structure Structure
TM4 181 R 4.64x64 AF2 AF2
TM4 182 V 4.65x65 AF2 AF2
TM4 183 S 4.66x66 AF2 AF2
TM4 184 W 4.67x67 AF2 AF2
TM4 185 E 4.68x68 AF2 AF2
ECL2 186 E - AF2 AF2
ECL2 187 G - AF2 AF2
ECL2 188 A - AF2 AF2
ECL2 189 P - AF2 AF2
ECL2 190 S - AF2 AF2
ECL2 191 V - AF2 AF2
ECL2 192 P - AF2 AF2
ECL2 193 P - AF2 AF2
ECL2 194 G - Structure Structure
ECL2 195 C 45.50x50 Structure Structure
ECL2 196 S 45.51x51 Structure Structure
ECL2 197 L 45.52x52 Structure Structure
ECL2 198 Q - Structure Structure
ECL2 199 W - Structure Structure
ECL2 200 S - Structure Structure
ECL2 201 H - Structure Structure
TM5 202 S 5.32x33 Structure Structure
TM5 203 A 5.33x34 Structure Structure
TM5 204 Y 5.34x35 Structure Structure
TM5 205 C 5.35x36 Structure Structure
TM5 206 Q 5.36x37 Structure Structure
TM5 207 L 5.37x38 Structure Structure
TM5 208 F 5.38x39 Structure Structure
TM5 209 V 5.39x40 Structure Structure
TM5 210 V 5.40x41 Structure Structure
TM5 211 V 5.41x42 Structure Structure
TM5 212 F 5.42x43 Structure Structure
TM5 213 A 5.43x44 Structure Structure
TM5 214 V 5.44x45 Structure Structure
TM5 215 L 5.45x46 Structure Structure
TM5 216 Y 5.46x461 Structure Structure
TM5 217 F 5.47x47 Structure Structure
TM5 218 L 5.48x48 Structure Structure
TM5 219 L 5.49x49 Structure Structure
TM5 220 P 5.50x50 Structure Structure
TM5 221 L 5.51x51 Structure Structure
TM5 222 L 5.52x52 Structure Structure
TM5 223 L 5.53x53 Structure Structure
TM5 224 I 5.54x54 Structure Structure
TM5 225 L 5.55x55 Structure Structure
TM5 226 V 5.56x56 Structure Structure
TM5 227 V 5.57x57 Structure Structure
TM5 228 Y 5.58x58 Structure Structure
TM5 229 C 5.59x59 Structure Structure
TM5 230 S 5.60x60 Structure Structure
TM5 231 M 5.61x61 Structure Structure
TM5 232 F 5.62x62 Structure Structure
TM5 233 R 5.63x63 Structure Structure
TM5 234 V 5.64x64 Structure Structure
TM5 235 A 5.65x65 Structure Structure
TM5 236 R 5.66x66 Structure Structure
TM5 237 V 5.67x67 Structure Structure
TM5 238 A 5.68x68 Structure Structure
TM5 239 A 5.69x69 AF2 AF2
TM5 240 M 5.70x70 AF2 AF2
TM5 241 Q 5.71x71 AF2 AF2
TM5 242 H 5.72x72 AF2 AF2
TM5 243 G 5.73x73 AF2 AF2
TM5 244 P 5.74x74 AF2 AF2
TM5 245 L 5.75x75 AF2 AF2
TM5 246 P 5.76x76 AF2 AF2
ICL3 247 T - AF2 AF2
ICL3 248 W - AF2 AF2
ICL3 249 M - AF2 AF2
ICL3 250 E - AF2 AF2
ICL3 251 T - AF2 AF2
ICL3 252 P - AF2 AF2
ICL3 253 R - AF2 AF2
ICL3 269 S - AF2 AF2
ICL3 270 G - AF2 AF2
ICL3 271 A - AF2 AF2
ICL3 272 P - AF2 AF2
ICL3 273 Q - AF2 AF2
ICL3 274 T - AF2 AF2
ICL3 275 T - AF2 AF2
TM6 276 P 6.24x24 AF2 AF2
TM6 277 H 6.25x25 AF2 AF2
TM6 278 R 6.26x26 AF2 AF2
TM6 279 T 6.27x27 AF2 AF2
TM6 280 F 6.28x28 AF2 AF2
TM6 281 G 6.29x29 AF2 AF2
TM6 282 G 6.30x30 AF2 AF2
TM6 283 G 6.31x31 Structure Structure
TM6 284 K 6.32x32 Structure Structure
TM6 285 A 6.33x33 Structure Structure
TM6 286 A 6.34x34 Structure Structure
TM6 287 V 6.35x35 Structure Structure
TM6 288 V 6.36x36 Structure Structure
TM6 289 L 6.37x37 Structure Structure
TM6 290 L 6.38x38 Structure Structure
TM6 291 A 6.39x39 Structure Structure
TM6 292 V 6.40x40 Structure Structure
TM6 293 G 6.41x41 Structure Structure
TM6 294 G 6.42x42 Structure Structure
TM6 295 Q 6.43x43 Structure Structure
TM6 296 F 6.44x44 Structure Structure
TM6 297 L 6.45x45 Structure Structure
TM6 298 L 6.46x46 Structure Structure
TM6 299 C 6.47x47 Structure Structure
TM6 300 W 6.48x48 Structure Structure
TM6 301 L 6.49x49 Structure Structure
TM6 302 P 6.50x50 Structure Structure
TM6 303 Y 6.51x51 Structure Structure
TM6 304 F 6.52x52 Structure Structure
TM6 305 S 6.53x53 Structure Structure
TM6 306 F 6.54x54 Structure Structure
TM6 307 H 6.55x55 Structure Structure
TM6 308 L 6.56x56 Structure Structure
TM6 309 Y 6.57x57 Structure Structure
TM6 310 V 6.58x58 Structure Structure
TM6 311 A 6.59x59 Structure Structure
TM6 312 L 6.60x60 Structure Structure
TM6 313 S 6.61x61 Structure Structure
ECL3 314 A - Structure Structure
ECL3 315 Q - Structure Structure
ECL3 316 P - Structure Structure
ECL3 317 I - Structure Structure
ECL3 318 S - Structure Structure
TM7 319 T 7.31x30 Structure Structure
TM7 320 G 7.32x31 Structure Structure
TM7 321 Q 7.33x32 Structure Structure
TM7 322 V 7.34x33 Structure Structure
TM7 323 E 7.35x34 Structure Structure
TM7 324 S 7.36x35 Structure Structure
TM7 325 V 7.37x36 Structure Structure
TM7 326 V 7.38x37 Structure Structure
TM7 327 T 7.39x38 Structure Structure
TM7 328 W 7.40x39 Structure Structure
TM7 329 I 7.41x40 Structure Structure
TM7 330 G 7.42x41 Structure Structure
TM7 331 Y 7.43x42 Structure Structure
TM7 332 F 7.44x43 Structure Structure
TM7 333 C 7.45x45 Structure Structure
TM7 334 F 7.46x46 Structure Structure
TM7 335 T 7.47x47 Structure Structure
TM7 336 S 7.48x48 Structure Structure
TM7 337 N 7.49x49 Structure Structure
TM7 338 P 7.50x50 Structure Structure
TM7 339 F 7.51x51 Structure Structure
TM7 340 F 7.52x52 Structure Structure
TM7 341 Y 7.53x53 Structure Structure
TM7 342 G 7.54x54 Structure Structure
TM7 343 C 7.55x55 Structure Structure
TM7 344 L 7.56x56 Structure Structure
H8 345 N 8.47x47 Structure Structure
H8 346 R 8.48x48 Structure Structure
H8 347 Q 8.49x49 Structure Structure
H8 348 I 8.50x50 Structure Structure
H8 349 R 8.51x51 Structure Structure
H8 350 G 8.52x52 Structure Structure
H8 351 E 8.53x53 Structure Structure
H8 352 L 8.54x54 Structure Structure
H8 353 S 8.55x55 Structure Structure
H8 354 K 8.56x56 AF2 AF2
H8 355 Q 8.57x57 AF2 AF2
H8 356 F 8.58x58 AF2 AF2
H8 357 V 8.59x59 AF2 AF2
C-term 358 C - AF2 AF2
C-term 359 F - AF2 AF2
C-term 360 F - AF2 AF2
C-term 361 K - AF2 AF2
C-term 362 P - AF2 AF2
C-term 363 A - AF2 AF2
C-term 364 P - AF2 AF2
C-term 365 E - AF2 AF2
C-term 366 E - AF2 AF2
C-term 367 E - AF2 AF2



GPCR - G protein interface interactions



The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.


Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):





Structures

Sequence Color

Gα, Gβ, Gγ, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Interaction
type		 GPCR
Segment
AA
Number		 Generic
number		 Gα
segment
AA
Number		 Generic
number
Hydrophobic TM3 V 144 3x54 G.H5 L 388 G.H5.20
Van-der-waals TM3 V 144 3x54 G.H5 L 388 G.H5.20
Hydrophobic ICL3 M 249 - G.H4 R 347 G.H4.17
Van-der-waals ICL3 M 249 - G.H4 R 347 G.H4.17
Hydrophobic H8 N 345 8x47 G.H5 Y 391 G.H5.23
Van-der-waals H8 N 345 8x47 G.H5 Y 391 G.H5.23
Hydrophobic ICL2 P 147 34x50 G.H5 R 380 G.H5.12
Polar TM5 Q 241 5x71 G.H5 R 385 G.H5.17
Van-der-waals TM5 Q 241 5x71 G.H5 R 385 G.H5.17
Polar TM3 Y 143 3x53 G.H5 Q 390 G.H5.22
Hydrophobic TM3 Y 143 3x53 G.H5 Q 390 G.H5.22
Van-der-waals TM3 Y 143 3x53 G.H5 Q 390 G.H5.22
Hydrophobic TM5 L 245 5x75 G.h4s6 T 350 G.h4s6.03
Van-der-waals TM5 L 245 5x75 G.h4s6 T 350 G.h4s6.03
Ionic H8 R 349 8x51 G.H5 E 392 G.H5.24
Polar H8 R 349 8x51 G.H5 E 392 G.H5.24
Hydrophobic H8 R 349 8x51 G.H5 E 392 G.H5.24
Van-der-waals H8 R 349 8x51 G.H5 E 392 G.H5.24
Hydrophobic ICL3 M 249 - G.h4s6 A 351 G.h4s6.04
Van-der-waals ICL3 M 249 - G.h4s6 A 351 G.h4s6.04
Hydrophobic ICL3 W 248 - G.h4s6 T 350 G.h4s6.03
Van-der-waals ICL3 W 248 - G.h4s6 T 350 G.h4s6.03
Hydrophobic TM5 A 238 5x68 G.H5 L 394 G.H5.26
Hydrophobic TM5 M 231 5x61 G.H5 Y 391 G.H5.23
Hydrophobic TM5 A 239 5x69 G.H5 L 394 G.H5.26
Hydrophobic TM5 A 235 5x65 G.H5 L 393 G.H5.25
Polar TM5 P 246 5x76 G.h4s6 T 350 G.h4s6.03
Hydrophobic TM5 P 246 5x76 G.h4s6 T 350 G.h4s6.03
Van-der-waals TM5 P 246 5x76 G.h4s6 T 350 G.h4s6.03
Polar H8 R 346 8x48 G.H5 R 389 G.H5.21
Aromatic TM3 R 140 3x50 G.H5 Y 391 G.H5.23
Hydrophobic TM3 R 140 3x50 G.H5 Y 391 G.H5.23
Hydrophobic TM3 V 144 3x54 G.H5 Y 391 G.H5.23
Van-der-waals TM3 V 144 3x54 G.H5 Y 391 G.H5.23
Hydrophobic ICL3 W 248 - G.H4 L 346 G.H4.16
Van-der-waals ICL3 W 248 - G.H4 L 346 G.H4.16
Polar TM3 Y 143 3x53 G.H5 H 387 G.H5.19
Aromatic TM3 Y 143 3x53 G.H5 H 387 G.H5.19
Hydrophobic TM3 Y 143 3x53 G.H5 H 387 G.H5.19
Van-der-waals TM3 Y 143 3x53 G.H5 H 387 G.H5.19
Hydrophobic ICL2 P 147 34x50 G.H5 I 383 G.H5.15
Hydrophobic TM3 V 144 3x54 G.H5 H 387 G.H5.19
Hydrophobic ICL2 M 148 34x51 G.H5 I 383 G.H5.15
Hydrophobic TM5 M 231 5x61 G.H5 L 393 G.H5.25
Van-der-waals TM5 M 231 5x61 G.H5 L 393 G.H5.25
Hydrophobic TM3 Y 143 3x53 G.H5 Y 391 G.H5.23
Van-der-waals TM3 Y 143 3x53 G.H5 Y 391 G.H5.23
Polar TM5 A 238 5x68 G.H5 R 385 G.H5.17
Hydrophobic TM5 A 238 5x68 G.H5 R 385 G.H5.17
Van-der-waals TM5 A 238 5x68 G.H5 R 385 G.H5.17
Hydrophobic TM5 L 245 5x75 G.h4s6 A 351 G.h4s6.04
Polar TM6 K 284 6x32 G.H5 E 392 G.H5.24
Hydrophobic TM6 K 284 6x32 G.H5 E 392 G.H5.24
Van-der-waals TM6 K 284 6x32 G.H5 E 392 G.H5.24
Ionic H8 R 346 8x48 G.H5 E 392 G.H5.24
Polar H8 R 346 8x48 G.H5 E 392 G.H5.24
Hydrophobic H8 R 346 8x48 G.H5 E 392 G.H5.24
Van-der-waals H8 R 346 8x48 G.H5 E 392 G.H5.24
Hydrophobic ICL3 M 249 - G.h4s6 I 348 G.h4s6.01
Van-der-waals ICL3 M 249 - G.h4s6 I 348 G.h4s6.01
Hydrophobic TM7 L 344 7x56 G.H5 Y 391 G.H5.23
Van-der-waals TM7 L 344 7x56 G.H5 Y 391 G.H5.23
Hydrophobic ICL2 M 148 34x51 G.S3 V 217 G.S3.01
Hydrophobic ICL2 P 147 34x50 G.H5 Q 384 G.H5.16
Van-der-waals ICL2 P 147 34x50 G.H5 Q 384 G.H5.16
Hydrophobic TM5 L 245 5x75 G.h4s6 G 353 G.h4s6.09
Van-der-waals TM5 L 245 5x75 G.h4s6 G 353 G.h4s6.09
Polar TM5 H 242 5x72 G.H5 R 385 G.H5.17
Hydrophobic TM5 H 242 5x72 G.H5 R 385 G.H5.17
Van-der-waals TM5 H 242 5x72 G.H5 R 385 G.H5.17
Hydrophobic TM6 A 285 6x33 G.H5 L 393 G.H5.25
Polar H8 Q 347 8x49 G.H5 Q 390 G.H5.22
Hydrophobic H8 Q 347 8x49 G.H5 Q 390 G.H5.22
Van-der-waals H8 Q 347 8x49 G.H5 Q 390 G.H5.22
Polar TM6 K 284 6x32 G.H5 L 394 G.H5.26
Hydrophobic TM6 K 284 6x32 G.H5 L 394 G.H5.26
Van-der-waals TM6 K 284 6x32 G.H5 L 394 G.H5.26
Van-der-waals TM7 L 344 7x56 G.H5 Q 390 G.H5.22
Hydrophobic ICL2 M 148 34x51 G.H5 F 376 G.H5.08
Van-der-waals ICL2 M 148 34x51 G.H5 F 376 G.H5.08
Hydrophobic ICL2 M 148 34x51 G.S1 H 41 G.S1.02
Van-der-waals ICL2 M 148 34x51 G.S1 H 41 G.S1.02
Hydrophobic TM5 L 245 5x75 G.h4s6 S 352 G.h4s6.08
Van-der-waals TM5 L 245 5x75 G.h4s6 S 352 G.h4s6.08
Hydrophobic ICL3 M 249 - G.h4s6 T 350 G.h4s6.03
Van-der-waals ICL3 M 249 - G.h4s6 T 350 G.h4s6.03
Hydrophobic ICL2 P 147 34x50 G.H5 H 387 G.H5.19
Van-der-waals ICL2 P 147 34x50 G.H5 H 387 G.H5.19
Polar TM3 V 145 3x55 G.H5 Q 384 G.H5.16
Van-der-waals TM3 V 145 3x55 G.H5 Q 384 G.H5.16
Hydrophobic TM6 V 288 6x36 G.H5 L 393 G.H5.25
Hydrophobic TM6 K 284 6x32 G.H5 L 393 G.H5.25
Hydrophobic TM5 L 245 5x75 G.h4s6 S 349 G.h4s6.02
Van-der-waals TM5 L 245 5x75 G.h4s6 S 349 G.h4s6.02
Aromatic ICL3 W 248 - G.H4 R 347 G.H4.17
Hydrophobic ICL3 W 248 - G.H4 R 347 G.H4.17
Van-der-waals ICL3 W 248 - G.H4 R 347 G.H4.17
Polar H8 R 346 8x48 G.H5 Q 390 G.H5.22
Hydrophobic H8 R 346 8x48 G.H5 Q 390 G.H5.22
Hydrophobic TM5 A 238 5x68 G.H5 L 388 G.H5.20
Hydrophobic TM5 A 235 5x65 G.H5 L 388 G.H5.20
Polar ICL2 E 151 34x54 G.HN Q 35 G.HN.52
Van-der-waals ICL2 E 151 34x54 G.HN Q 35 G.HN.52
Aromatic TM5 H 242 5x72 G.h4s6 Y 358 G.h4s6.20
Hydrophobic TM5 H 242 5x72 G.h4s6 Y 358 G.h4s6.20
Van-der-waals TM5 H 242 5x72 G.h4s6 Y 358 G.h4s6.20
Hydrophobic ICL2 M 148 34x51 G.S3 F 219 G.S3.03
Polar TM3 V 144 3x54 G.H5 Q 384 G.H5.16