GPCRdb

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Ligand source activities (1 row/activity)

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

	CHEMBL2219665	84439	None	0	Human	Binding	IC50	=	1071.52	5.97	-	1	Antagonist activity at human P2Y13	ChEMBL	430.0	7	3	9	3.49	Cc1nc(/N=N/c2cc([N+](=O)[O-])ccc2Cl)c(COP(=O)(O)O)c(C=O)c1O	https://dx.doi.org/10.1021/acs.jmedchem.5b01972
	MRS2603	2653	None	10	Human	Binding	IC50	=	660.69	6.18	-	1	Antagonist activity at human P2Y13	ChEMBL	430.0	7	3	8	1.62	CC1=N/C(=N\Nc2ccc(Cl)c([N+](=O)[O-])c2)C(COP(=O)(O)O)=C(C=O)C1=O	https://dx.doi.org/10.1021/acs.jmedchem.5b01972
	PPADS	3153	None	14	Human	Binding	IC50	=	11600.00	4.94	-	6	Antagonist activity at P2Y13 (unknown origin)	ChEMBL	511.0	8	5	11	1.43	Cc1nc(/N=N/c2ccc(S(=O)(=O)O)cc2S(=O)(=O)O)c(COP(=O)(O)O)c(C=O)c1O	https://dx.doi.org/10.1021/acs.jmedchem.5b01972
	reactive blue-2	3296	None	17	Human	Binding	IC50	=	1900.00	5.72	-	10	Antagonist activity at P2Y13 (unknown origin)	ChEMBL	773.0	9	7	15	3.85	Nc1c(S(=O)(=O)O)cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(S(=O)(=O)O)c4)n3)c(S(=O)(=O)O)c2)c2c1C(=O)c1ccccc1C2=O	https://dx.doi.org/10.1021/acs.jmedchem.5b01972
	suramin	3710	None	26	Human	Binding	IC50	=	2300.00	5.64	-	11	Antagonist activity at P2Y13 (unknown origin)	ChEMBL	1296.0	16	12	17	6.74	Cc1ccc(C(=O)Nc2ccc(S(=O)(=O)O)c3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)cc1NC(=O)c1cccc(NC(=O)Nc2cccc(C(=O)Nc3cc(C(=O)Nc4ccc(S(=O)(=O)O)c5cc(S(=O)(=O)O)cc(S(=O)(=O)O)c45)ccc3C)c2)c1	https://dx.doi.org/10.1021/acs.jmedchem.5b01972

Showing 1 to 5 of 5 entries

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI