Refined structure (8IRV) of Gs - D5 receptor

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

Gs

DATE

2024-02-01

3D VIEW

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Structure
GPCR
Gα
Gβ
Gγ
Model
AlphaFold2-Multimer

REFINED G PROTEIN RESIDUES

Residue backbones - 238 from structure (60.4%), 156 from model (39.6%)
Residue sidechains - 216 from structure (54.8%), 178 from model (45.2%)
Segment Seq.num. AA CGN# Backbone from Sidechain from
G.HN 1 M G.HN.01 AF2 AF2
G.HN 2 G G.HN.02 AF2 AF2
G.HN 3 C G.HN.09 AF2 AF2
G.HN 4 L G.HN.10 AF2 AF2
G.HN 5 G G.HN.11 AF2 AF2
G.HN 6 N G.HN.22 AF2 AF2
G.HN 7 S G.HN.23 AF2 AF2
G.HN 8 K G.HN.24 AF2 AF2
G.HN 9 T G.HN.26 AF2 AF2
G.HN 10 E G.HN.27 Structure AF2
G.HN 11 D G.HN.28 Structure AF2
G.HN 12 Q G.HN.29 Structure AF2
G.HN 13 R G.HN.30 Structure AF2
G.HN 14 N G.HN.31 Structure AF2
G.HN 15 E G.HN.32 Structure Structure
G.HN 16 E G.HN.33 Structure AF2
G.HN 17 K G.HN.34 Structure Structure
G.HN 18 A G.HN.35 Structure Structure
G.HN 19 Q G.HN.36 Structure AF2
G.HN 20 R G.HN.37 Structure AF2
G.HN 21 E G.HN.38 Structure Structure
G.HN 22 A G.HN.39 Structure AF2
G.HN 23 N G.HN.40 Structure AF2
G.HN 24 K G.HN.41 Structure Structure
G.HN 25 K G.HN.42 Structure AF2
G.HN 26 I G.HN.43 Structure Structure
G.HN 27 E G.HN.44 Structure Structure
G.HN 28 K G.HN.45 Structure Structure
G.HN 29 Q G.HN.46 Structure Structure
G.HN 30 L G.HN.47 Structure Structure
G.HN 31 Q G.HN.48 Structure Structure
G.HN 32 K G.HN.49 Structure Structure
G.HN 33 D G.HN.50 Structure Structure
G.HN 34 K G.HN.51 Structure Structure
G.HN 35 Q G.HN.52 Structure Structure
G.HN 36 V G.HN.53 Structure Structure
G.hns1 37 Y G.hns1.01 Structure Structure
G.hns1 38 R G.hns1.02 Structure Structure
G.hns1 39 A G.hns1.03 Structure Structure
G.S1 40 T G.S1.01 Structure Structure
G.S1 41 H G.S1.02 Structure Structure
G.S1 42 R G.S1.03 Structure Structure
G.S1 43 L G.S1.04 Structure Structure
G.S1 44 L G.S1.05 Structure Structure
G.S1 45 L G.S1.06 Structure Structure
G.S1 46 L G.S1.07 Structure Structure
G.s1h1 47 G G.s1h1.01 Structure Structure
G.s1h1 48 A G.s1h1.02 Structure Structure
G.s1h1 49 G G.s1h1.03 Structure AF2
G.s1h1 50 E G.s1h1.04 Structure AF2
G.s1h1 51 S G.s1h1.05 Structure Structure
G.s1h1 52 G G.s1h1.06 Structure Structure
G.H1 53 K G.H1.01 Structure Structure
G.H1 54 S G.H1.02 Structure Structure
G.H1 55 T G.H1.03 Structure Structure
G.H1 56 I G.H1.04 Structure Structure
G.H1 57 V G.H1.05 Structure Structure
G.H1 58 K G.H1.06 Structure Structure
G.H1 59 Q G.H1.07 Structure Structure
G.H1 60 M G.H1.08 Structure Structure
G.H1 61 R G.H1.09 Structure Structure
G.H1 62 I G.H1.10 Structure Structure
G.H1 63 L G.H1.11 Structure AF2
G.H1 64 H G.H1.12 Structure Structure
G.h1ha 65 V G.h1ha.01 AF2 AF2
G.h1ha 66 N G.h1ha.02 AF2 AF2
G.h1ha 67 G G.h1ha.03 AF2 AF2
G.h1ha 68 F G.h1ha.04 AF2 AF2
G.h1ha 69 N G.h1ha.05 AF2 AF2
G.h1ha 70 G G.h1ha.06 AF2 AF2
G.h1ha 71 E G.h1ha.07 AF2 AF2
G.h1ha 72 G G.h1ha.08 AF2 AF2
G.h1ha 73 G G.h1ha.09 AF2 AF2
G.h1ha 74 E G.h1ha.10 AF2 AF2
G.h1ha 75 E G.h1ha.11 AF2 AF2
G.h1ha 76 D G.h1ha.12 AF2 AF2
G.h1ha 77 P G.h1ha.13 AF2 AF2
G.h1ha 78 Q G.h1ha.14 AF2 AF2
G.h1ha 79 A G.h1ha.15 AF2 AF2
G.h1ha 80 A G.h1ha.16 AF2 AF2
G.h1ha 81 R G.h1ha.17 AF2 AF2
G.h1ha 82 S G.h1ha.18 AF2 AF2
G.h1ha 83 N G.h1ha.19 AF2 AF2
G.h1ha 84 S G.h1ha.20 AF2 AF2
H.HA 85 D H.HA.01 AF2 AF2
H.HA 86 G H.HA.02 AF2 AF2
H.HA 87 E H.HA.03 AF2 AF2
H.HA 88 K H.HA.04 AF2 AF2
H.HA 89 A H.HA.05 AF2 AF2
H.HA 90 T H.HA.06 AF2 AF2
H.HA 91 K H.HA.07 AF2 AF2
H.HA 92 V H.HA.08 AF2 AF2
H.HA 93 Q H.HA.09 AF2 AF2
H.HA 94 D H.HA.10 AF2 AF2
H.HA 95 I H.HA.11 AF2 AF2
H.HA 96 K H.HA.12 AF2 AF2
H.HA 97 N H.HA.13 AF2 AF2
H.HA 98 N H.HA.14 AF2 AF2
H.HA 99 L H.HA.15 AF2 AF2
H.HA 100 K H.HA.16 AF2 AF2
H.HA 101 E H.HA.17 AF2 AF2
H.HA 102 A H.HA.18 AF2 AF2
H.HA 103 I H.HA.19 AF2 AF2
H.HA 104 E H.HA.20 AF2 AF2
H.HA 105 T H.HA.21 AF2 AF2
H.HA 106 I H.HA.22 AF2 AF2
H.HA 107 V H.HA.23 AF2 AF2
H.HA 108 A H.HA.24 AF2 AF2
H.HA 109 A H.HA.25 AF2 AF2
H.HA 110 M H.HA.26 AF2 AF2
H.HA 111 S H.HA.27 AF2 AF2
H.HA 112 N H.HA.28 AF2 AF2
H.HA 113 L H.HA.29 AF2 AF2
H.hahb 114 V H.hahb.01 AF2 AF2
H.hahb 115 P H.hahb.02 AF2 AF2
H.hahb 116 P H.hahb.03 AF2 AF2
H.hahb 117 V H.hahb.04 AF2 AF2
H.hahb 118 E H.hahb.05 AF2 AF2
H.hahb 119 L H.hahb.06 AF2 AF2
H.hahb 120 A H.hahb.07 AF2 AF2
H.hahb 121 N H.hahb.08 AF2 AF2
H.hahb 122 P H.hahb.09 AF2 AF2
H.HB 123 E H.HB.01 AF2 AF2
H.HB 124 N H.HB.02 AF2 AF2
H.HB 125 Q H.HB.03 AF2 AF2
H.HB 126 F H.HB.04 AF2 AF2
H.HB 127 R H.HB.05 AF2 AF2
H.HB 128 V H.HB.06 AF2 AF2
H.HB 129 D H.HB.07 AF2 AF2
H.HB 130 Y H.HB.08 AF2 AF2
H.HB 131 I H.HB.09 AF2 AF2
H.HB 132 L H.HB.10 AF2 AF2
H.HB 133 S H.HB.11 AF2 AF2
H.HB 134 V H.HB.12 AF2 AF2
H.HB 135 M H.HB.13 AF2 AF2
H.HB 136 N H.HB.14 AF2 AF2
H.hbhc 137 V H.hbhc.01 AF2 AF2
H.hbhc 138 P H.hbhc.02 AF2 AF2
H.hbhc 139 D H.hbhc.03 AF2 AF2
H.hbhc 140 F H.hbhc.04 AF2 AF2
H.hbhc 141 D H.hbhc.13 AF2 AF2
H.hbhc 142 F H.hbhc.14 AF2 AF2
H.hbhc 143 P H.hbhc.15 AF2 AF2
H.HC 144 P H.HC.01 AF2 AF2
H.HC 145 E H.HC.02 AF2 AF2
H.HC 146 F H.HC.03 AF2 AF2
H.HC 147 Y H.HC.04 AF2 AF2
H.HC 148 E H.HC.05 AF2 AF2
H.HC 149 H H.HC.06 AF2 AF2
H.HC 150 A H.HC.07 AF2 AF2
H.HC 151 K H.HC.08 AF2 AF2
H.HC 152 A H.HC.09 AF2 AF2
H.HC 153 L H.HC.10 AF2 AF2
H.HC 154 W H.HC.11 AF2 AF2
H.HC 155 E H.HC.12 AF2 AF2
H.hchd 156 D H.hchd.01 AF2 AF2
H.HD 157 E H.HD.01 AF2 AF2
H.HD 158 G H.HD.02 AF2 AF2
H.HD 159 V H.HD.03 AF2 AF2
H.HD 160 R H.HD.04 AF2 AF2
H.HD 161 A H.HD.05 AF2 AF2
H.HD 162 C H.HD.06 AF2 AF2
H.HD 163 Y H.HD.07 AF2 AF2
H.HD 164 E H.HD.08 AF2 AF2
H.HD 165 R H.HD.09 AF2 AF2
H.HD 166 S H.HD.10 AF2 AF2
H.HD 167 N H.HD.11 AF2 AF2
H.HD 168 E H.HD.12 AF2 AF2
H.hdhe 169 Y H.hdhe.01 AF2 AF2
H.hdhe 170 Q H.hdhe.02 AF2 AF2
H.hdhe 171 L H.hdhe.03 AF2 AF2
H.hdhe 172 I H.hdhe.04 AF2 AF2
H.hdhe 173 D H.hdhe.05 AF2 AF2
H.HE 174 C H.HE.01 AF2 AF2
H.HE 175 A H.HE.02 AF2 AF2
H.HE 176 Q H.HE.03 AF2 AF2
H.HE 177 Y H.HE.04 AF2 AF2
H.HE 178 F H.HE.05 AF2 AF2
H.HE 179 L H.HE.06 AF2 AF2
H.HE 180 D H.HE.07 AF2 AF2
H.HE 181 K H.HE.08 AF2 AF2
H.HE 182 I H.HE.09 AF2 AF2
H.HE 183 D H.HE.10 AF2 AF2
H.HE 184 V H.HE.11 AF2 AF2
H.HE 185 I H.HE.12 AF2 AF2
H.HE 186 K H.HE.13 AF2 AF2
H.hehf 187 Q H.hehf.01 AF2 AF2
H.hehf 188 A H.hehf.02 AF2 AF2
H.hehf 189 D H.hehf.03 AF2 AF2
H.hehf 190 Y H.hehf.04 AF2 AF2
H.hehf 191 V H.hehf.05 AF2 AF2
H.hehf 192 P H.hehf.06 AF2 AF2
H.hehf 193 S H.hehf.07 AF2 AF2
H.HF 194 D H.HF.01 AF2 AF2
H.HF 195 Q H.HF.02 AF2 AF2
H.HF 196 D H.HF.03 AF2 AF2
H.HF 197 L H.HF.04 AF2 AF2
H.HF 198 L H.HF.05 AF2 AF2
H.HF 199 R H.HF.06 AF2 AF2
G.hfs2 200 C G.hfs2.01 AF2 AF2
G.hfs2 201 R G.hfs2.02 AF2 AF2
G.hfs2 202 V G.hfs2.03 Structure Structure
G.hfs2 203 L G.hfs2.04 Structure AF2
G.hfs2 204 T G.hfs2.05 Structure Structure
G.hfs2 205 S G.hfs2.06 Structure Structure
G.hfs2 206 G G.hfs2.07 Structure Structure
G.S2 207 I G.S2.01 Structure Structure
G.S2 208 F G.S2.02 Structure Structure
G.S2 209 E G.S2.03 Structure Structure
G.S2 210 T G.S2.04 Structure Structure
G.S2 211 K G.S2.05 Structure Structure
G.S2 212 F G.S2.06 Structure Structure
G.S2 213 Q G.S2.07 Structure Structure
G.S2 214 V G.S2.08 Structure Structure
G.s2s3 215 D G.s2s3.01 Structure Structure
G.s2s3 216 K G.s2s3.02 Structure Structure
G.S3 217 V G.S3.01 Structure Structure
G.S3 218 N G.S3.02 Structure Structure
G.S3 219 F G.S3.03 Structure Structure
G.S3 220 H G.S3.04 Structure Structure
G.S3 221 M G.S3.05 Structure Structure
G.S3 222 F G.S3.06 Structure Structure
G.S3 223 D G.S3.07 Structure Structure
G.S3 224 V G.S3.08 Structure Structure
G.s3h2 225 G G.s3h2.01 Structure Structure
G.s3h2 226 G G.s3h2.02 Structure AF2
G.s3h2 227 Q G.s3h2.03 Structure Structure
G.H2 228 R G.H2.01 Structure Structure
G.H2 229 D G.H2.02 Structure Structure
G.H2 230 E G.H2.03 Structure Structure
G.H2 231 R G.H2.04 Structure Structure
G.H2 232 R G.H2.05 Structure Structure
G.H2 233 K G.H2.06 Structure Structure
G.H2 234 W G.H2.07 Structure Structure
G.H2 235 I G.H2.08 Structure Structure
G.H2 236 Q G.H2.09 Structure Structure
G.H2 237 C G.H2.10 Structure Structure
G.h2s4 238 F G.h2s4.01 Structure Structure
G.h2s4 239 N G.h2s4.02 Structure Structure
G.h2s4 240 D G.h2s4.03 Structure Structure
G.h2s4 241 V G.h2s4.04 Structure Structure
G.h2s4 242 T G.h2s4.05 Structure Structure
G.S4 243 A G.S4.01 Structure Structure
G.S4 244 I G.S4.02 Structure Structure
G.S4 245 I G.S4.03 Structure Structure
G.S4 246 F G.S4.04 Structure Structure
G.S4 247 V G.S4.05 Structure Structure
G.S4 248 V G.S4.06 Structure Structure
G.S4 249 A G.S4.07 Structure AF2
G.s4h3 250 S G.s4h3.01 Structure Structure
G.s4h3 251 S G.s4h3.02 Structure Structure
G.s4h3 252 S G.s4h3.03 Structure AF2
G.s4h3 253 Y G.s4h3.04 Structure Structure
G.s4h3 254 N G.s4h3.05 Structure Structure
G.s4h3 255 M G.s4h3.06 AF2 AF2
G.s4h3 256 V G.s4h3.07 AF2 AF2
G.s4h3 257 I G.s4h3.08 AF2 AF2
G.s4h3 258 R G.s4h3.09 AF2 AF2
G.s4h3 259 E G.s4h3.10 AF2 AF2
G.s4h3 260 D G.s4h3.11 AF2 AF2
G.s4h3 261 N G.s4h3.12 AF2 AF2
G.s4h3 262 Q G.s4h3.13 AF2 AF2
G.s4h3 263 T G.s4h3.14 AF2 AF2
G.s4h3 264 N G.s4h3.15 AF2 AF2
G.H3 265 R G.H3.01 Structure Structure
G.H3 266 L G.H3.02 Structure Structure
G.H3 267 Q G.H3.03 Structure Structure
G.H3 268 E G.H3.04 Structure Structure
G.H3 269 A G.H3.05 Structure Structure
G.H3 270 L G.H3.06 Structure Structure
G.H3 271 N G.H3.07 Structure Structure
G.H3 272 L G.H3.08 Structure AF2
G.H3 273 F G.H3.09 Structure Structure
G.H3 274 K G.H3.10 Structure Structure
G.H3 275 S G.H3.11 Structure Structure
G.H3 276 I G.H3.12 Structure Structure
G.H3 277 W G.H3.13 Structure Structure
G.H3 278 N G.H3.14 Structure Structure
G.H3 279 N G.H3.15 Structure Structure
G.H3 280 R G.H3.16 Structure Structure
G.H3 281 W G.H3.17 Structure Structure
G.H3 282 L G.H3.18 Structure Structure
G.h3s5 283 R G.h3s5.01 Structure Structure
G.h3s5 284 T G.h3s5.02 Structure Structure
G.h3s5 285 I G.h3s5.03 Structure Structure
G.S5 286 S G.S5.01 Structure Structure
G.S5 287 V G.S5.02 Structure Structure
G.S5 288 I G.S5.03 Structure Structure
G.S5 289 L G.S5.04 Structure Structure
G.S5 290 F G.S5.05 Structure Structure
G.S5 291 L G.S5.06 Structure Structure
G.S5 292 N G.S5.07 Structure Structure
G.s5hg 293 K G.s5hg.01 Structure Structure
G.HG 294 Q G.HG.01 Structure Structure
G.HG 295 D G.HG.02 Structure Structure
G.HG 296 L G.HG.03 Structure Structure
G.HG 297 L G.HG.04 Structure Structure
G.HG 298 A G.HG.05 Structure Structure
G.HG 299 E G.HG.06 Structure Structure
G.HG 300 K G.HG.07 Structure Structure
G.HG 301 V G.HG.08 Structure Structure
G.HG 302 L G.HG.09 Structure Structure
G.HG 303 A G.HG.10 Structure Structure
G.HG 304 G G.HG.11 Structure Structure
G.HG 305 K G.HG.12 Structure Structure
G.HG 306 S G.HG.13 Structure Structure
G.HG 307 K G.HG.14 Structure Structure
G.HG 308 I G.HG.15 Structure Structure
G.HG 309 E G.HG.16 Structure Structure
G.HG 310 D G.HG.17 Structure Structure
G.hgh4 311 Y G.hgh4.01 Structure Structure
G.hgh4 312 F G.hgh4.02 Structure Structure
G.hgh4 313 P G.hgh4.03 Structure Structure
G.hgh4 314 E G.hgh4.04 Structure Structure
G.hgh4 315 F G.hgh4.05 Structure Structure
G.hgh4 316 A G.hgh4.06 Structure Structure
G.hgh4 317 R G.hgh4.07 Structure Structure
G.hgh4 318 Y G.hgh4.08 Structure Structure
G.hgh4 319 T G.hgh4.09 Structure Structure
G.hgh4 320 T G.hgh4.10 Structure Structure
G.hgh4 321 P G.hgh4.11 Structure Structure
G.hgh4 322 E G.hgh4.12 Structure Structure
G.hgh4 323 D G.hgh4.13 Structure Structure
G.hgh4 324 A G.hgh4.14 Structure Structure
G.hgh4 325 T G.hgh4.15 Structure Structure
G.hgh4 326 P G.hgh4.16 Structure Structure
G.hgh4 327 E G.hgh4.17 Structure Structure
G.hgh4 328 P G.hgh4.18 Structure Structure
G.hgh4 329 G G.hgh4.19 Structure Structure
G.hgh4 330 E G.hgh4.20 Structure Structure
G.hgh4 331 D G.hgh4.21 Structure Structure
G.H4 332 P G.H4.01 Structure Structure
G.H4 333 R G.H4.02 Structure Structure
G.H4 334 V G.H4.03 Structure Structure
G.H4 335 T G.H4.04 Structure Structure
G.H4 336 R G.H4.05 Structure Structure
G.H4 337 A G.H4.06 Structure Structure
G.H4 338 K G.H4.07 Structure Structure
G.H4 339 Y G.H4.08 Structure Structure
G.H4 340 F G.H4.10 Structure Structure
G.H4 341 I G.H4.11 Structure Structure
G.H4 342 R G.H4.12 Structure Structure
G.H4 343 D G.H4.13 Structure Structure
G.H4 344 E G.H4.14 Structure Structure
G.H4 345 F G.H4.15 Structure Structure
G.H4 346 L G.H4.16 Structure Structure
G.H4 347 R G.H4.17 Structure Structure
G.h4s6 348 I G.h4s6.01 Structure Structure
G.h4s6 349 S G.h4s6.02 Structure Structure
G.h4s6 350 T G.h4s6.03 Structure Structure
G.h4s6 351 A G.h4s6.04 Structure Structure
G.h4s6 352 S G.h4s6.08 Structure Structure
G.h4s6 353 G G.h4s6.09 Structure Structure
G.h4s6 354 D G.h4s6.10 Structure Structure
G.h4s6 355 G G.h4s6.11 Structure Structure
G.h4s6 356 R G.h4s6.12 Structure Structure
G.h4s6 357 H G.h4s6.13 Structure Structure
G.h4s6 358 Y G.h4s6.20 Structure Structure
G.S6 359 C G.S6.01 Structure Structure
G.S6 360 Y G.S6.02 Structure Structure
G.S6 361 P G.S6.03 Structure Structure
G.S6 362 H G.S6.04 Structure Structure
G.S6 363 F G.S6.05 Structure Structure
G.s6h5 364 T G.s6h5.01 Structure Structure
G.s6h5 365 C G.s6h5.02 Structure Structure
G.s6h5 366 A G.s6h5.03 Structure AF2
G.s6h5 367 V G.s6h5.04 Structure Structure
G.s6h5 368 D G.s6h5.05 Structure Structure
G.H5 369 T G.H5.01 Structure Structure
G.H5 370 E G.H5.02 Structure Structure
G.H5 371 N G.H5.03 Structure Structure
G.H5 372 I G.H5.04 Structure AF2
G.H5 373 R G.H5.05 Structure Structure
G.H5 374 R G.H5.06 Structure Structure
G.H5 375 V G.H5.07 Structure AF2
G.H5 376 F G.H5.08 Structure Structure
G.H5 377 N G.H5.09 Structure Structure
G.H5 378 D G.H5.10 Structure Structure
G.H5 379 C G.H5.11 Structure Structure
G.H5 380 R G.H5.12 Structure Structure
G.H5 381 D G.H5.13 Structure Structure
G.H5 382 I G.H5.14 Structure Structure
G.H5 383 I G.H5.15 Structure Structure
G.H5 384 Q G.H5.16 Structure Structure
G.H5 385 R G.H5.17 Structure Structure
G.H5 386 M G.H5.18 Structure Structure
G.H5 387 H G.H5.19 Structure Structure
G.H5 388 L G.H5.20 Structure Structure
G.H5 389 R G.H5.21 Structure Structure
G.H5 390 Q G.H5.22 Structure Structure
G.H5 391 Y G.H5.23 Structure Structure
G.H5 392 E G.H5.24 Structure Structure
G.H5 393 L G.H5.25 Structure Structure
G.H5 394 L G.H5.26 Structure Structure

REFINED GPCR RESIDUES

Residue backbones - 278 from structure (72.4%), 106 from model (27.6%)
Residue sidechains - 278 from structure (72.4%), 106 from model (27.6%)
Segment Seq.num. AA GPCRdb# Backbone from Sidechain from
N-term 1 M - AF2 AF2
N-term 2 L - AF2 AF2
N-term 3 P - AF2 AF2
N-term 4 P - AF2 AF2
N-term 5 G - AF2 AF2
N-term 6 S - AF2 AF2
N-term 7 N - AF2 AF2
N-term 8 G - AF2 AF2
N-term 9 T - AF2 AF2
N-term 10 A - AF2 AF2
N-term 11 Y - AF2 AF2
N-term 12 P - AF2 AF2
N-term 13 G - AF2 AF2
N-term 14 Q - AF2 AF2
N-term 15 F - AF2 AF2
N-term 16 A - AF2 AF2
N-term 17 L - AF2 AF2
N-term 18 Y - AF2 AF2
N-term 19 Q - AF2 AF2
N-term 20 Q - AF2 AF2
N-term 21 L - AF2 AF2
N-term 22 A - AF2 AF2
N-term 23 Q - AF2 AF2
N-term 24 G - AF2 AF2
N-term 25 N - AF2 AF2
N-term 26 A - AF2 AF2
N-term 27 V - AF2 AF2
N-term 28 G - AF2 AF2
N-term 29 G - AF2 AF2
N-term 30 S - AF2 AF2
N-term 31 A - AF2 AF2
N-term 32 G - AF2 AF2
N-term 33 A - AF2 AF2
N-term 34 P - AF2 AF2
N-term 35 P - AF2 AF2
N-term 36 L - AF2 AF2
N-term 37 G - AF2 AF2
TM1 38 P 1.30x30 Structure Structure
TM1 39 S 1.31x31 Structure Structure
TM1 40 Q 1.32x32 Structure Structure
TM1 41 V 1.33x33 Structure Structure
TM1 42 V 1.34x34 Structure Structure
TM1 43 T 1.35x35 Structure Structure
TM1 44 A 1.36x36 Structure Structure
TM1 45 C 1.37x37 Structure Structure
TM1 46 L 1.38x38 Structure Structure
TM1 47 L 1.39x39 Structure Structure
TM1 48 T 1.40x40 Structure Structure
TM1 49 L 1.41x41 Structure Structure
TM1 50 L 1.42x42 Structure Structure
TM1 51 I 1.43x43 Structure Structure
TM1 52 I 1.44x44 Structure Structure
TM1 53 W 1.45x45 Structure Structure
TM1 54 T 1.46x46 Structure Structure
TM1 55 L 1.47x47 Structure Structure
TM1 56 L 1.48x48 Structure Structure
TM1 57 G 1.49x49 Structure Structure
TM1 58 N 1.50x50 Structure Structure
TM1 59 V 1.51x51 Structure Structure
TM1 60 L 1.52x52 Structure Structure
TM1 61 V 1.53x53 Structure Structure
TM1 62 C 1.54x54 Structure Structure
TM1 63 A 1.55x55 Structure Structure
TM1 64 A 1.56x56 Structure Structure
TM1 65 I 1.57x57 Structure Structure
TM1 66 V 1.58x58 Structure Structure
TM1 67 R 1.59x59 Structure Structure
TM1 68 S 1.60x60 Structure Structure
ICL1 69 R 12.48x48 Structure Structure
ICL1 70 H 12.49x49 Structure Structure
ICL1 71 L 12.50x50 Structure Structure
ICL1 72 R 12.51x51 Structure Structure
ICL1 73 A 12.52x52 Structure Structure
TM2 74 N 2.37x37 Structure Structure
TM2 75 M 2.38x38 Structure Structure
TM2 76 T 2.39x39 Structure Structure
TM2 77 N 2.40x40 Structure Structure
TM2 78 V 2.41x41 Structure Structure
TM2 79 F 2.42x42 Structure Structure
TM2 80 I 2.43x43 Structure Structure
TM2 81 V 2.44x44 Structure Structure
TM2 82 S 2.45x45 Structure Structure
TM2 83 L 2.46x46 Structure Structure
TM2 84 A 2.47x47 Structure Structure
TM2 85 V 2.48x48 Structure Structure
TM2 86 S 2.49x49 Structure Structure
TM2 87 D 2.50x50 Structure Structure
TM2 88 L 2.51x51 Structure Structure
TM2 89 F 2.52x52 Structure Structure
TM2 90 V 2.53x53 Structure Structure
TM2 91 A 2.54x54 Structure Structure
TM2 92 L 2.55x55 Structure Structure
TM2 93 L 2.56x551 Structure Structure
TM2 94 V 2.57x56 Structure Structure
TM2 95 M 2.58x57 Structure Structure
TM2 96 P 2.59x58 Structure Structure
TM2 97 W 2.60x59 Structure Structure
TM2 98 K 2.61x60 Structure Structure
TM2 99 A 2.62x61 Structure Structure
TM2 100 V 2.63x62 Structure Structure
TM2 101 A 2.64x63 Structure Structure
TM2 102 E 2.65x64 Structure Structure
TM2 103 V 2.66x65 Structure Structure
TM2 104 A 2.67x66 Structure Structure
TM2 105 G 2.68x67 Structure Structure
ECL1 106 Y 23.49x49 Structure Structure
ECL1 107 W 23.50x50 Structure Structure
ECL1 108 P 23.51x51 Structure Structure
ECL1 109 F 23.52x52 Structure Structure
TM3 110 G 3.22x22 Structure Structure
TM3 111 A 3.23x23 Structure Structure
TM3 112 F 3.24x24 Structure Structure
TM3 113 C 3.25x25 Structure Structure
TM3 114 D 3.26x26 Structure Structure
TM3 115 V 3.27x27 Structure Structure
TM3 116 W 3.28x28 Structure Structure
TM3 117 V 3.29x29 Structure Structure
TM3 118 A 3.30x30 Structure Structure
TM3 119 F 3.31x31 Structure Structure
TM3 120 D 3.32x32 Structure Structure
TM3 121 I 3.33x33 Structure Structure
TM3 122 M 3.34x34 Structure Structure
TM3 123 C 3.35x35 Structure Structure
TM3 124 S 3.36x36 Structure Structure
TM3 125 T 3.37x37 Structure Structure
TM3 126 A 3.38x38 Structure Structure
TM3 127 S 3.39x39 Structure Structure
TM3 128 I 3.40x40 Structure Structure
TM3 129 L 3.41x41 Structure Structure
TM3 130 N 3.42x42 Structure Structure
TM3 131 L 3.43x43 Structure Structure
TM3 132 C 3.44x44 Structure Structure
TM3 133 V 3.45x45 Structure Structure
TM3 134 I 3.46x46 Structure Structure
TM3 135 S 3.47x47 Structure Structure
TM3 136 V 3.48x48 Structure Structure
TM3 137 D 3.49x49 Structure Structure
TM3 138 R 3.50x50 Structure Structure
TM3 139 Y 3.51x51 Structure Structure
TM3 140 W 3.52x52 Structure Structure
TM3 141 A 3.53x53 Structure Structure
TM3 142 I 3.54x54 Structure Structure
TM3 143 S 3.55x55 Structure Structure
TM3 144 R 3.56x56 Structure Structure
ICL2 145 P 34.50x50 Structure Structure
ICL2 146 F 34.51x51 Structure Structure
ICL2 147 R 34.52x52 Structure Structure
ICL2 148 Y 34.53x53 Structure Structure
ICL2 149 K 34.54x54 Structure Structure
ICL2 150 R 34.55x55 Structure Structure
ICL2 151 K 34.56x56 Structure Structure
ICL2 152 M 34.57x57 Structure Structure
TM4 153 T 4.38x38 Structure Structure
TM4 154 Q 4.39x39 Structure Structure
TM4 155 R 4.40x40 Structure Structure
TM4 156 M 4.41x41 Structure Structure
TM4 157 A 4.42x42 Structure Structure
TM4 158 L 4.43x43 Structure Structure
TM4 159 V 4.44x44 Structure Structure
TM4 160 M 4.45x45 Structure Structure
TM4 161 V 4.46x46 Structure Structure
TM4 162 G 4.47x47 Structure Structure
TM4 163 L 4.48x48 Structure Structure
TM4 164 A 4.49x49 Structure Structure
TM4 165 W 4.50x50 Structure Structure
TM4 166 T 4.51x51 Structure Structure
TM4 167 L 4.52x52 Structure Structure
TM4 168 S 4.53x53 Structure Structure
TM4 169 I 4.54x54 Structure Structure
TM4 170 L 4.55x55 Structure Structure
TM4 171 I 4.56x56 Structure Structure
TM4 172 S 4.57x57 Structure Structure
TM4 173 F 4.58x58 Structure Structure
TM4 174 I 4.59x59 Structure Structure
TM4 175 P 4.60x60 Structure Structure
TM4 176 V 4.61x61 Structure Structure
TM4 177 Q 4.62x62 Structure Structure
TM4 178 L 4.63x63 Structure Structure
TM4 179 N 4.64x64 Structure Structure
ECL2 180 W - Structure Structure
ECL2 181 H - Structure Structure
ECL2 182 R - Structure Structure
ECL2 183 D - Structure Structure
ECL2 184 Q - AF2 AF2
ECL2 185 A - AF2 AF2
ECL2 186 A - AF2 AF2
ECL2 187 S - AF2 AF2
ECL2 188 W - AF2 AF2
ECL2 189 G - AF2 AF2
ECL2 190 G - AF2 AF2
ECL2 191 L - AF2 AF2
ECL2 192 D - AF2 AF2
ECL2 193 L - AF2 AF2
ECL2 194 P - AF2 AF2
ECL2 195 N - AF2 AF2
ECL2 196 N - AF2 AF2
ECL2 197 L - AF2 AF2
ECL2 198 A - AF2 AF2
ECL2 199 N - AF2 AF2
ECL2 200 W - AF2 AF2
ECL2 201 T - AF2 AF2
ECL2 202 P - AF2 AF2
ECL2 203 W - AF2 AF2
ECL2 204 E - AF2 AF2
ECL2 205 E - AF2 AF2
ECL2 206 D - AF2 AF2
ECL2 207 F - AF2 AF2
ECL2 208 W - AF2 AF2
ECL2 209 E - AF2 AF2
ECL2 210 P - AF2 AF2
ECL2 211 D - AF2 AF2
ECL2 212 V - AF2 AF2
ECL2 213 N - AF2 AF2
ECL2 214 A - AF2 AF2
ECL2 215 E - Structure Structure
ECL2 216 N - Structure Structure
ECL2 217 C 45.50x50 Structure Structure
ECL2 218 D 45.51x51 Structure Structure
ECL2 219 S 45.52x52 Structure Structure
ECL2 220 S - Structure Structure
ECL2 221 L - Structure Structure
TM5 222 N 5.35x36 Structure Structure
TM5 223 R 5.36x37 Structure Structure
TM5 224 T 5.37x38 Structure Structure
TM5 225 Y 5.38x39 Structure Structure
TM5 226 A 5.39x40 Structure Structure
TM5 227 I 5.40x41 Structure Structure
TM5 228 S 5.41x42 Structure Structure
TM5 229 S 5.42x43 Structure Structure
TM5 230 S 5.43x44 Structure Structure
TM5 231 L 5.44x45 Structure Structure
TM5 232 I 5.45x46 Structure Structure
TM5 233 S 5.46x461 Structure Structure
TM5 234 F 5.47x47 Structure Structure
TM5 235 Y 5.48x48 Structure Structure
TM5 236 I 5.49x49 Structure Structure
TM5 237 P 5.50x50 Structure Structure
TM5 238 V 5.51x51 Structure Structure
TM5 239 A 5.52x52 Structure Structure
TM5 240 I 5.53x53 Structure Structure
TM5 241 M 5.54x54 Structure Structure
TM5 242 I 5.55x55 Structure Structure
TM5 243 V 5.56x56 Structure Structure
TM5 244 T 5.57x57 Structure Structure
TM5 245 Y 5.58x58 Structure Structure
TM5 246 T 5.59x59 Structure Structure
TM5 247 R 5.60x60 Structure Structure
TM5 248 I 5.61x61 Structure Structure
TM5 249 Y 5.62x62 Structure Structure
TM5 250 R 5.63x63 Structure Structure
TM5 251 I 5.64x64 Structure Structure
TM5 252 A 5.65x65 Structure Structure
TM5 253 Q 5.66x66 Structure Structure
TM5 254 V 5.67x67 Structure Structure
TM5 255 Q 5.68x68 Structure Structure
TM5 256 I 5.69x69 Structure Structure
TM5 257 R 5.70x70 Structure Structure
TM5 258 R 5.71x71 Structure Structure
TM5 259 I 5.72x72 Structure Structure
TM5 260 S 5.73x73 Structure Structure
TM5 261 S 5.74x74 Structure Structure
TM5 262 L 5.75x75 Structure Structure
TM5 263 E 5.76x76 Structure Structure
TM5 264 R 5.77x77 Structure Structure
TM5 265 A 5.78x78 Structure Structure
TM5 266 A 5.79x79 Structure Structure
TM5 267 E 5.80x80 Structure Structure
TM5 268 H 5.81x81 Structure Structure
TM5 269 A 5.82x82 Structure Structure
TM5 270 Q 5.83x83 Structure Structure
TM5 271 S 5.84x84 Structure Structure
TM5 272 C 5.85x85 AF2 AF2
TM5 273 R 5.86x86 AF2 AF2
ICL3 274 S - AF2 AF2
ICL3 275 S - AF2 AF2
ICL3 276 A - AF2 AF2
ICL3 277 A - AF2 AF2
ICL3 278 C - AF2 AF2
ICL3 279 A - AF2 AF2
ICL3 280 P - AF2 AF2
ICL3 281 D - AF2 AF2
ICL3 282 T - AF2 AF2
ICL3 283 S - AF2 AF2
ICL3 284 L - AF2 AF2
TM6 285 R 6.24x24 AF2 AF2
TM6 286 A 6.25x25 AF2 AF2
TM6 287 S 6.26x26 AF2 AF2
TM6 288 I 6.27x27 AF2 AF2
TM6 289 K 6.28x28 Structure Structure
TM6 290 K 6.29x29 Structure Structure
TM6 291 E 6.30x30 Structure Structure
TM6 292 T 6.31x31 Structure Structure
TM6 293 K 6.32x32 Structure Structure
TM6 294 V 6.33x33 Structure Structure
TM6 295 L 6.34x34 Structure Structure
TM6 296 K 6.35x35 Structure Structure
TM6 297 T 6.36x36 Structure Structure
TM6 298 L 6.37x37 Structure Structure
TM6 299 S 6.38x38 Structure Structure
TM6 300 V 6.39x39 Structure Structure
TM6 301 I 6.40x40 Structure Structure
TM6 302 M 6.41x41 Structure Structure
TM6 303 G 6.42x42 Structure Structure
TM6 304 V 6.43x43 Structure Structure
TM6 305 F 6.44x44 Structure Structure
TM6 306 V 6.45x45 Structure Structure
TM6 307 C 6.46x46 Structure Structure
TM6 308 C 6.47x47 Structure Structure
TM6 309 W 6.48x48 Structure Structure
TM6 310 L 6.49x49 Structure Structure
TM6 311 P 6.50x50 Structure Structure
TM6 312 F 6.51x51 Structure Structure
TM6 313 F 6.52x52 Structure Structure
TM6 314 I 6.53x53 Structure Structure
TM6 315 L 6.54x54 Structure Structure
TM6 316 N 6.55x55 Structure Structure
TM6 317 C 6.56x56 Structure Structure
TM6 318 M 6.57x57 Structure Structure
TM6 319 V 6.58x58 Structure Structure
TM6 320 P 6.59x59 Structure Structure
TM6 321 F 6.60x60 Structure Structure
TM6 322 C 6.61x61 Structure Structure
ECL3 323 S - Structure Structure
ECL3 324 G - AF2 AF2
ECL3 325 H - AF2 AF2
ECL3 326 P - AF2 AF2
ECL3 327 E - AF2 AF2
ECL3 328 G - AF2 AF2
ECL3 329 P - AF2 AF2
ECL3 330 P - AF2 AF2
ECL3 331 A - AF2 AF2
ECL3 332 G - AF2 AF2
ECL3 333 F - AF2 AF2
ECL3 334 P - AF2 AF2
ECL3 335 C - Structure Structure
ECL3 336 V - Structure Structure
TM7 337 S 7.31x30 Structure Structure
TM7 338 E 7.32x31 Structure Structure
TM7 339 T 7.33x32 Structure Structure
TM7 340 T 7.34x33 Structure Structure
TM7 341 F 7.35x34 Structure Structure
TM7 342 D 7.36x35 Structure Structure
TM7 343 V 7.37x36 Structure Structure
TM7 344 F 7.38x37 Structure Structure
TM7 345 V 7.39x38 Structure Structure
TM7 346 W 7.40x39 Structure Structure
TM7 347 F 7.41x40 Structure Structure
TM7 348 G 7.42x41 Structure Structure
TM7 349 W 7.43x42 Structure Structure
TM7 350 A 7.44x43 Structure Structure
TM7 351 N 7.45x45 Structure Structure
TM7 352 S 7.46x46 Structure Structure
TM7 353 S 7.47x47 Structure Structure
TM7 354 L 7.48x48 Structure Structure
TM7 355 N 7.49x49 Structure Structure
TM7 356 P 7.50x50 Structure Structure
TM7 357 V 7.51x51 Structure Structure
TM7 358 I 7.52x52 Structure Structure
TM7 359 Y 7.53x53 Structure Structure
TM7 360 A 7.54x54 Structure Structure
TM7 361 F 7.55x55 Structure Structure
H8 362 N 8.47x47 Structure Structure
H8 363 A 8.48x48 Structure Structure
H8 364 D 8.49x49 Structure Structure
H8 365 F 8.50x50 Structure Structure
H8 366 Q 8.51x51 Structure Structure
H8 367 K 8.52x52 Structure Structure
H8 368 V 8.53x53 Structure Structure
H8 369 F 8.54x54 Structure Structure
H8 370 A 8.55x55 Structure Structure
H8 371 Q 8.56x56 Structure Structure
H8 372 L 8.57x57 Structure Structure
H8 373 L 8.58x58 Structure Structure
H8 374 G 8.59x59 Structure Structure
C-term 375 C - AF2 AF2
C-term 376 S - AF2 AF2
C-term 377 H - AF2 AF2
C-term 378 F - AF2 AF2
C-term 379 C - AF2 AF2
C-term 380 S - AF2 AF2
C-term 381 R - AF2 AF2
C-term 382 T - AF2 AF2
C-term 383 P - AF2 AF2
C-term 384 V - AF2 AF2



GPCR - G protein interface interactions



The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.


Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):





Structures

Sequence Color

Gα, Gβ, Gγ, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Interaction
type		 GPCR
Segment
AA
Number		 Generic
number		 Gα
segment
AA
Number		 Generic
number
Polar TM5 R 273 5x86 G.hgh4 R 317 G.hgh4.07
Hydrophobic TM5 R 273 5x86 G.hgh4 R 317 G.hgh4.07
Van-der-waals TM5 R 273 5x86 G.hgh4 R 317 G.hgh4.07
Hydrophobic ICL2 K 149 34x54 G.H5 I 383 G.H5.15
Hydrophobic TM5 L 262 5x75 G.S6 P 361 G.S6.03
Hydrophobic TM6 V 294 6x33 G.H5 L 393 G.H5.25
Van-der-waals TM6 V 294 6x33 G.H5 L 393 G.H5.25
Hydrophobic ICL2 F 146 34x51 G.H5 R 380 G.H5.12
Van-der-waals ICL2 F 146 34x51 G.H5 R 380 G.H5.12
Hydrophobic TM5 I 259 5x72 G.H5 L 394 G.H5.26
Polar ICL2 R 150 34x55 G.hns1 R 38 G.hns1.02
Van-der-waals ICL2 R 150 34x55 G.hns1 R 38 G.hns1.02
Ionic TM5 R 264 5x77 G.hgh4 D 323 G.hgh4.13
Polar TM5 R 264 5x77 G.hgh4 D 323 G.hgh4.13
Hydrophobic TM5 R 264 5x77 G.hgh4 D 323 G.hgh4.13
Van-der-waals TM5 R 264 5x77 G.hgh4 D 323 G.hgh4.13
Hydrophobic TM5 A 269 5x82 G.H4 D 343 G.H4.13
Van-der-waals TM5 A 269 5x82 G.H4 D 343 G.H4.13
Aromatic TM3 R 138 3x50 G.H5 Y 391 G.H5.23
Hydrophobic TM3 R 138 3x50 G.H5 Y 391 G.H5.23
Polar TM5 H 268 5x81 G.hgh4 T 319 G.hgh4.09
Hydrophobic TM5 H 268 5x81 G.hgh4 T 319 G.hgh4.09
Van-der-waals TM5 H 268 5x81 G.hgh4 T 319 G.hgh4.09
Hydrophobic TM5 I 248 5x61 G.H5 L 393 G.H5.25
Van-der-waals TM5 I 248 5x61 G.H5 L 393 G.H5.25
Aromatic ICL2 F 146 34x51 G.S1 H 41 G.S1.02
Hydrophobic ICL2 F 146 34x51 G.S1 H 41 G.S1.02
Van-der-waals ICL2 F 146 34x51 G.S1 H 41 G.S1.02
Hydrophobic TM6 T 297 6x36 G.H5 L 393 G.H5.25
Van-der-waals TM6 T 297 6x36 G.H5 L 393 G.H5.25
Hydrophobic ICL2 K 149 34x54 G.S1 H 41 G.S1.02
Ionic ICL2 R 150 34x55 G.h1ha E 75 G.h1ha.11
Hydrophobic ICL2 R 150 34x55 G.h1ha E 75 G.h1ha.11
Van-der-waals ICL2 R 150 34x55 G.h1ha E 75 G.h1ha.11
Hydrophobic TM5 A 266 5x79 G.H4 L 346 G.H4.16
Hydrophobic TM5 R 273 5x86 G.H4 R 347 G.H4.17
Van-der-waals TM5 R 273 5x86 G.H4 R 347 G.H4.17
Polar TM3 A 141 3x53 G.H5 H 387 G.H5.19
Hydrophobic TM3 A 141 3x53 G.H5 H 387 G.H5.19
Van-der-waals TM3 A 141 3x53 G.H5 H 387 G.H5.19
Ionic TM5 R 273 5x86 G.hgh4 E 314 G.hgh4.04
Polar TM5 R 273 5x86 G.hgh4 E 314 G.hgh4.04
Hydrophobic TM5 R 273 5x86 G.hgh4 E 314 G.hgh4.04
Van-der-waals TM5 R 273 5x86 G.hgh4 E 314 G.hgh4.04
Hydrophobic ICL2 R 150 34x55 G.hns1 A 39 G.hns1.03
Polar TM6 K 293 6x32 G.H5 L 394 G.H5.26
Hydrophobic TM6 K 293 6x32 G.H5 L 394 G.H5.26
Van-der-waals TM6 K 293 6x32 G.H5 L 394 G.H5.26
Hydrophobic TM5 I 259 5x72 G.H5 R 385 G.H5.17
Van-der-waals TM5 I 259 5x72 G.H5 R 385 G.H5.17
Hydrophobic TM3 I 142 3x54 G.H5 H 387 G.H5.19
Aromatic ICL2 F 146 34x51 G.H5 F 376 G.H5.08
Hydrophobic ICL2 F 146 34x51 G.H5 F 376 G.H5.08
Van-der-waals ICL2 F 146 34x51 G.H5 F 376 G.H5.08
Hydrophobic TM6 L 298 6x37 G.H5 L 393 G.H5.25
Polar TM5 C 272 5x85 G.hgh4 R 317 G.hgh4.07
Hydrophobic TM5 C 272 5x85 G.hgh4 R 317 G.hgh4.07
Van-der-waals TM5 C 272 5x85 G.hgh4 R 317 G.hgh4.07
Hydrophobic TM6 K 293 6x32 G.H5 E 392 G.H5.24
Polar TM5 A 269 5x82 G.H4 R 347 G.H4.17
Hydrophobic TM5 A 269 5x82 G.H4 R 347 G.H4.17
Van-der-waals TM5 A 269 5x82 G.H4 R 347 G.H4.17
Hydrophobic ICL2 P 145 34x50 G.H5 I 383 G.H5.15
Van-der-waals ICL2 P 145 34x50 G.H5 I 383 G.H5.15
Hydrophobic TM5 I 251 5x64 G.H5 Q 384 G.H5.16
Ionic TM5 R 258 5x71 G.H5 D 381 G.H5.13
Polar TM5 R 258 5x71 G.H5 D 381 G.H5.13
Van-der-waals TM5 R 258 5x71 G.H5 D 381 G.H5.13
Hydrophobic TM6 K 290 6x29 G.H5 L 394 G.H5.26
Van-der-waals TM6 K 290 6x29 G.H5 L 394 G.H5.26
Hydrophobic ICL2 F 146 34x51 G.H5 C 379 G.H5.11
Hydrophobic TM5 A 252 5x65 G.H5 L 388 G.H5.20
Hydrophobic ICL2 P 145 34x50 G.H5 R 380 G.H5.12
Hydrophobic TM5 A 265 5x78 G.H4 L 346 G.H4.16
Hydrophobic TM5 C 272 5x85 G.hgh4 Y 318 G.hgh4.08
Van-der-waals TM5 C 272 5x85 G.hgh4 Y 318 G.hgh4.08
Hydrophobic TM5 I 259 5x72 G.h4s6 Y 358 G.h4s6.20
Polar TM5 Q 255 5x68 G.H5 R 385 G.H5.17
Hydrophobic TM5 Q 255 5x68 G.H5 R 385 G.H5.17
Van-der-waals TM5 Q 255 5x68 G.H5 R 385 G.H5.17
Hydrophobic TM5 A 266 5x79 G.H4 R 347 G.H4.17
Hydrophobic ICL2 P 145 34x50 G.H5 Q 384 G.H5.16
Van-der-waals ICL2 P 145 34x50 G.H5 Q 384 G.H5.16
Hydrophobic TM3 I 142 3x54 G.H5 Y 391 G.H5.23
Van-der-waals TM3 I 142 3x54 G.H5 Y 391 G.H5.23
Hydrophobic ICL2 F 146 34x51 G.S3 F 219 G.S3.03
Hydrophobic TM5 A 269 5x82 G.hgh4 Y 318 G.hgh4.08
Hydrophobic TM4 T 153 4x38 G.hns1 R 38 G.hns1.02
Hydrophobic ICL2 F 146 34x51 G.H5 I 383 G.H5.15
Van-der-waals ICL2 F 146 34x51 G.H5 I 383 G.H5.15
Hydrophobic ICL2 Y 148 34x53 G.H5 H 387 G.H5.19
Polar TM5 Q 255 5x68 G.H5 Q 384 G.H5.16
Van-der-waals TM5 Q 255 5x68 G.H5 Q 384 G.H5.16
Polar TM3 I 142 3x54 G.H5 Q 384 G.H5.16
Van-der-waals TM3 I 142 3x54 G.H5 Q 384 G.H5.16
Polar H8 N 362 8x47 G.H5 Q 390 G.H5.22
Hydrophobic TM5 L 262 5x75 G.H4 L 346 G.H4.16
Polar TM5 Q 270 5x83 G.H4 R 347 G.H4.17
Hydrophobic TM5 Q 270 5x83 G.H4 R 347 G.H4.17
Van-der-waals TM5 Q 270 5x83 G.H4 R 347 G.H4.17
Hydrophobic TM5 I 256 5x69 G.H5 L 394 G.H5.26
Van-der-waals TM5 I 256 5x69 G.H5 L 394 G.H5.26
Hydrophobic TM5 Q 255 5x68 G.H5 L 388 G.H5.20
Hydrophobic TM5 E 263 5x76 G.h4s6 T 350 G.h4s6.03
Polar TM5 Q 255 5x68 G.H5 D 381 G.H5.13
Hydrophobic TM5 Q 255 5x68 G.H5 D 381 G.H5.13
Van-der-waals TM5 Q 255 5x68 G.H5 D 381 G.H5.13
Van-der-waals TM5 A 265 5x78 G.H4 R 342 G.H4.12
Polar ICL2 K 149 34x54 G.hns1 R 38 G.hns1.02
Van-der-waals ICL2 K 149 34x54 G.hns1 R 38 G.hns1.02
Hydrophobic ICL2 F 146 34x51 G.S3 V 217 G.S3.01
Polar TM6 T 297 6x36 G.H5 E 392 G.H5.24
Van-der-waals TM6 T 297 6x36 G.H5 E 392 G.H5.24
Hydrophobic TM3 I 142 3x54 G.H5 L 388 G.H5.20
Van-der-waals TM3 I 142 3x54 G.H5 L 388 G.H5.20
Ionic TM5 R 273 5x86 G.H4 E 344 G.H4.14
Polar TM5 R 273 5x86 G.H4 E 344 G.H4.14
Hydrophobic TM5 R 273 5x86 G.H4 E 344 G.H4.14
Van-der-waals TM5 R 273 5x86 G.H4 E 344 G.H4.14
Polar TM3 S 143 3x55 G.H5 R 380 G.H5.12
Van-der-waals TM3 S 143 3x55 G.H5 R 380 G.H5.12
Hydrophobic TM3 I 142 3x54 G.H5 L 393 G.H5.25
Hydrophobic TM5 A 266 5x79 G.h4s6 T 350 G.h4s6.03
Van-der-waals TM5 A 266 5x79 G.h4s6 T 350 G.h4s6.03